| BASEC ID | Project title | Type of project | Type of clinical trial | Study phase (clinical trials only) | multi- / monocentric | Category | Principal investigator | Sponsor | Investigational sites | Lead EC | Local EC(s) | Approval date | Minors | Study Ended | |
|---|---|---|---|---|---|---|---|---|---|---|---|---|---|---|---|
| 2026-00282 | Can diagnostic quality of thoraco-abdominal CT performed with a reduced dose of iodinated contrast medium be adequate, thanking the use of Photon-Counting Detector CT (PCCT) technology in oncologic im More ... | non clinical, involving persons | monocentric | A | Prof dr med Stefania Rizzo | Ente Ospedaliero Cantonale |
Ente Ospedaliero Cantonale, Lugano |
Comitato etico cantonale Ticino | 20.03.2026 | ||||||
| 2026-00280 | Understanding Youth’ Use, Perceptions, and Participation in Public Spaces in Basel-Stadt: An Exploratory Mixed-Methods Research Project | non clinical, involving persons | monocentric | A | Prof. Mirko Winkler | Swiss Tropical and Public Health Institute |
Swiss Tropical and Public Health Institute, Allschwil |
Ethikkommission Nordwest- und Zentralschweiz EKNZ | 11.03.2026 | yes | |||||
| 2026-00277 | Virtual extemporaneous histopathological assessment of sentinel lymph nodes with 3D X-ray grating interferometric imaging | non clinical, involving persons | monocentric | A | PD Dr med Simone Schiaffino | Ente Ospedaliero Cantonale |
Ente Ospedaliero Cantonale, Lugano |
Comitato etico cantonale Ticino | 29.04.2026 | ||||||
| 2026-00275 |
Behandlung depressiver Symptomatik mit Helleborus niger: Eine retrospektive beobachtende Studie auf Basis von PHQ9-Scores und ICD-11-Diagnosen |
personal data/biological material | monocentric | Prof Dr David Martin | Rontalpraxis |
Universität Witten Herdecke, 58313 Herdecke |
Ethikkommission Nordwest- und Zentralschweiz EKNZ | 26.02.2026 | |||||||
| 2026-00273 | Investigating pediatric tumors and neuroblastoma disease to improve biological understanding and develop new treatments | non clinical, involving persons | monocentric | A | Porf. Dr. med. Stephanie Gros | UKBB/ University of Basel |
UKBB, Basel |
Ethikkommission Nordwest- und Zentralschweiz EKNZ | 23.03.2026 | yes | |||||
| 2026-00271 | Master's thesis on the topic: Conservative versus surgical treatment of distraction type fractures in ankylosing spinal disorders: a comparative study | non clinical, involving persons | monocentric | A | Lukas Urbanschitz | Universitätsspital Basel |
Universitätsspital Basel, Basel |
Ethikkommission Nordwest- und Zentralschweiz EKNZ | 11.03.2026 | ||||||
| 2026-00270 | Cognitive profiles in relation to brain malformations, Epilepsy and genetics in Children, Adolescents and adults with LAMA2- Related Muscular Dystrophy (LAMA2-RD) | non clinical, involving persons | monocentric | A | Prof. Dr. med. Andrea Klein | Neuropädiatrie, Rehabilitation und Entwicklung Universitätsklinik für Kinderheilkunde |
Neuropädiatrie, Rehabilitation und Entwicklung , Universitätsklinik für Kinderheilkunde, Bern |
Kantonale Ethikkommission Bern | 31.03.2026 | yes | |||||
| 2026-00268 | Visus und Kontrastsensitivität des Auges | non clinical, involving persons | monocentric | A | Dr. Martin Lörtscher | Fachhochschule Nordwestschweiz |
Fachhochschule Nordwestschweiz, Institut für Optometrie, Olten |
Ethikkommission Nordwest- und Zentralschweiz EKNZ | 22.04.2026 | ||||||
| 2026-00267 | Pilot Study on Classification of Activities of Daily Living in Manual Wheelchair Users | non clinical, involving persons | monocentric | A | Dr. Diego Paez-Granados | ETHZ / SPF |
Swiss Paraplegic Research, Nottwil |
Ethikkommission Nordwest- und Zentralschweiz EKNZ | 21.04.2026 | ||||||
| 2026-00266 | TRUMATCH-Mobility of cancellous bone graft in segmental femoral bone defects under simulated physiological motion- a Cadaver Study | deceased persons | monocentric | PD Dr. med. Mario Morgenstern | University Hospital |
Universitätsspital Basel, Zentrum für muskuloskelettale Infektionen, Basel |
Ethikkommission Nordwest- und Zentralschweiz EKNZ | 30.03.2026 | |||||||
| 2026-00265 | Post-Radiotherapy Follow-Up of Basal Cell Carcinoma and Lentigo maligna using Line-Field Confocal Optical Coherence Tomography (LC-OCT): A Prospective Observational Study | non clinical, involving persons | monocentric | A | Dr. med. Dr. sc. med. Egle Ramelyte | Universitätsspital Zürich |
Universitätsspital Zürich, Zürich |
Kantonale Ethikkommission Zürich | 08.05.2026 | ||||||
| 2026-00264 | Investigating factors predicting iron absorption in order to improve iron supplementation | personal data/biological material | monocentric | Prof. Nicole Stoffel | ETH Zurich |
ETH Zurich, Zurich |
Kantonale Ethikkommission Zürich | 29.04.2026 | |||||||
| 2026-00263 | The Role of Cholinergic Signalling in Allogenic Hematopoietic Stem Cell Transplantation | personal data/biological material | monocentric | Prof. Dr. Petya Apostolova | University Hospital Basel |
University Hospital Basel, Basel |
Ethikkommission Nordwest- und Zentralschweiz EKNZ | 16.04.2026 | |||||||
| 2026-00259 | Détecter la reconnaissance d’objets en analysant l’activité cérébrale | non clinical, involving persons | monocentric | A | Dr Jérôme Barral | Université de Lausanne |
Université de Lausanne, Lausanne |
Commission cantonale d'Éthique de la Recherche sur l'être humain Vaud (CER-VD) | 07.04.2026 | ||||||
| 2026-00255 | From Under-reporting to Prevention: Real-World Evidence on the Burden, Costs, and Vaccination Impact of Influenza, SARS-CoV-2, and RSV in Swiss Adults | personal data/biological material | monocentric | Dr. med. Dr. sc. med. Maria Bösing | Kantonsspital Baselland |
Kantonsspital Baselland, Liestal |
Ethikkommission Nordwest- und Zentralschweiz EKNZ | 11.02.2026 | |||||||
| 2026-00254 | Extending the prediction power of proton therapy outcomes beyond the dose-volume paradigm - the EXTEND project | personal data/biological material | monocentric | Dr. Arturs Meijers | Center for Proton Therapy at Paul Scherrer Institut |
Center for Proton Therapy at Paul Scherrer Institut, Villigen |
Ethikkommission Nordwest- und Zentralschweiz EKNZ | 11.02.2026 | |||||||
| 2026-00253 | Post-authorization safety study of iptacopan in adult patients with paroxysmal nocturnal hemoglobinuria (PNH) using data from the non-interventional IPIG PNH Registry | personal data/biological material | monocentric | Jocelyn Buisker | Novartis Pharma AG |
Novartis Pharma AG, Basel |
Ethikkommission Nordwest- und Zentralschweiz EKNZ | 24.02.2026 | |||||||
| 2026-00252 | A single-centre open-label parallel two-arms pilot randomized clinical trial of a booster Recombinant Zoster vaccine in Solid-Organ Transplant Recipients | clinical trial | drugs | phase 2 | monocentric | B | Professeur Oriol Manuel | CHUV - Maladies Infectieuses |
Centre Hospitalier Universitaire Vaudois (CHUV), Lausanne |
Commission cantonale d'Éthique de la Recherche sur l'être humain Vaud (CER-VD) | 20.04.2026 | ||||
| 2026-00248 | Programmable shunt valves for intrathecal chemotherapy delivery in infants with high-grade central nervous system tumors and hydrocephalus | personal data/biological material | monocentric | Prof. Dr. med. Jehuda Soleman | Tel Aviv Sourasky Medical Centre |
Neurochirurgie, Universitätsspital basel, Basel |
Ethikkommission Nordwest- und Zentralschweiz EKNZ | 11.03.2026 | |||||||
| 2026-00247 | Hunting for the long-Term EffeCts of P2Y12 inhibitor monotHerapy and coagulation monitoring after PCI (HI-TECH 2): an open-label, randomized study | clinical trial | drugs | phase 3 | monocentric | A | Prof. Marco Valgimigli | Istituto Cardiocentro Ticino- EOC |
Istituto Cardiocentro Ticino, Lugano |
Comitato etico cantonale Ticino | 07.04.2026 | ||||