| BASEC ID | Project title | Type of project | Type of clinical trial | Study phase (clinical trials only) | multi- / monocentric | Category | Principal investigator | Sponsor | Investigational sites | Lead EC | Local EC(s) | Approval date | Minors | Study Ended | |
|---|---|---|---|---|---|---|---|---|---|---|---|---|---|---|---|
| 2022-02076 | Exacerbations of Alpha-1 Antitrypsin Deficiency Lung Disease: Impact and Role of Augmentation Therapy | non clinical, involving persons | monocentric | A | PD Dr. med. Christian Clarenbach | University Hospital Zurich |
University Hospital Zurich, Department of Pulmonology, Zurich |
Kantonale Ethikkommission Zürich | 24.01.2023 | ||||||
| 2022-02075 | Artificial Intelligence for the Immune Profiling of Hepatocellular Carcinoma | personal data/biological material | monocentric | Dr. med. Iuliana-Pompilia Radu | UVCM Hepatology |
UVCM Hepatology, Bern |
Kantonale Ethikkommission Bern | 24.02.2023 | Study has ended | ||||||
| 2022-02073 |
Title: Automated detection of midface fractures using texture analysis Short title: AI-based automated midface fracture detection |
personal data/biological material | monocentric | Prof. Dr. Thomas Frauenfelder | DIR, UniversitätsSpital Zürich |
UniversitätsSpital Zürich, Zürich |
Kantonale Ethikkommission Zürich | 10.01.2023 | |||||||
| 2022-02072 | Similarities between left and right knee in terms of coronal, rotational and sagittal alignments. | personal data/biological material | monocentric | Prof. Michael T. Hirschmann | Kantonsspital Baselland |
Kantonsspital Baselland, Bruderholz |
Ethikkommission Nordwest- und Zentralschweiz EKNZ | 04.01.2023 | |||||||
| 2022-02071 | Predicting disease activity and rebound risk in MS patients treated with Sphingosine-1-Phosphate Receptor Modulators (S1PRM) - a biomarker study - The PATTERN Study | non clinical, involving persons | monocentric | A | PD Dr. med. Robert Hoepner |
Inselspital, Bern |
Kantonale Ethikkommission Bern | 31.01.2023 | |||||||
| 2022-02070 | Point-of-care measurement of Antifibrinolytic Activity of Tranexamic Acid in Cardiac Surgery | clinical trial | drugs | n/a | monocentric | A | Prof. Dr. Dr. med. Gabor Erdoes |
Inselspital, University hospital, Bern |
Kantonale Ethikkommission Bern | 24.02.2023 | |||||
| 2022-02069 | Conversion of Hip Resurfacing to Total Hip Arthroplasty: Is the outcome closer to Primary or Revision Total Hip Arthroplasty? | personal data/biological material | monocentric | Pr Julien Wegrzyn | CHUV - DAL - Orthopédie |
CHUV, Lausanne |
Commission cantonale d'Éthique de la Recherche sur l'être humain Vaud (CER-VD) | 10.01.2023 | Study has ended | ||||||
| 2022-02067 | Récidive du syndrome du tunnel carpien : résultats après prise en charge par neurolyse et lambeau synovial | personal data/biological material | monocentric | Prof. Jean-Yves Beaulieu | Hôpitaux Universitaires de Genève |
Hôpitaux Universitaires de Genève, Genève |
Commission Cantonale d'éthique de la recherche Genève (CCER) | 13.02.2023 | |||||||
| 2022-02066 | Epidemiology of methicillin-resistant Staphylococcus aureus (MRSA) and vancomycin-resistant Enterococcus spp. (VRE) colonization and infection in Swiss solid organ transplant recipients and risk facto More ... | personal data/biological material | multicentric | Prof. Dr. med. Nicolas Müller | University Hospital Zurich |
UniversitätsSpital Zürich, Zürich University Hospital Berne, Berne University Hospital Basel, Basel University Hospitals Geneva, Geneva Cantonal Hospital St. Gallen, St. Gallen University Hospital Lau More ... |
Kantonale Ethikkommission Zürich | Ethikkommission Nordwest- und Zentralschweiz EKNZ, Ethikkommission Ostschweiz (EKOS), Kantonale Ethikkommission Bern, Commission cantonale d'Éthique de la Recherche sur l'être humain Vaud (CER-VD), Co More ... | 17.02.2023 | ||||||
| 2022-02065 | Total Shoulder Arthroplasty Multi-Center Registry | non clinical, involving persons | monocentric | A | Prof. Dr. Philipp Moroder | Arthrex GmbH |
Schulthess Klinik, Zürich |
Kantonale Ethikkommission Zürich | 17.03.2023 | ||||||
| 2022-02064 | Comparaison entre les formes de libération immédiate et de libération prolongée du tacrolimus dans le contexte de la transplantation pulmonaire | personal data/biological material | monocentric | PD MER Dr. med Angela Koutsokera | CHUV - Pneumologie |
CHUV, Lausanne |
Commission cantonale d'Éthique de la Recherche sur l'être humain Vaud (CER-VD) | 05.01.2023 | |||||||
| 2022-02063 | Isolation and cultivation of bacteria from human saliva samples | non clinical, involving persons | monocentric | A | Dr. Alexander Zipperer | F. Hoffmann-La Roche Ltd |
F. Hoffmann - La Roche AG, Basel |
Ethikkommission Nordwest- und Zentralschweiz EKNZ | 11.01.2023 | ||||||
| 2022-02062 | Retrospective analysis of independency from glasses and quality of vision after cataract surgery with extended monovision. | personal data/biological material | monocentric | Dr.med. univ. (GR) Dimitrios Kyroudis | Pallas Klinik Olten |
Pallas Kliniken Olten, Olten |
Ethikkommission Nordwest- und Zentralschweiz EKNZ | 15.03.2023 | |||||||
| 2022-02061 | ARCR-SWE - Evaluation of functional and biomechanical outcome by shear-wave elastography in the short to intermediate follow-up after arthroscopic rotator cuff repair | non clinical, involving persons | monocentric | A | Dr Dominik Bühler | University Hospital Basel |
USB, Basel |
Ethikkommission Nordwest- und Zentralschweiz EKNZ | 22.12.2022 | ||||||
| 2022-02058 | Prospective observational study of dermatological immune-related adverse events in oncology patients receiving immune checkpoint inhibitors | non clinical, involving persons | monocentric | A | PD Dr. med. et. Dr. phil. nat. Laurence Feldmeyer |
Universitätsklinik für Dermatologie, Bern |
Kantonale Ethikkommission Bern | 20.03.2023 | |||||||
| 2022-02056 | Thrombin generation assay for evaluation of hemostasis in patients with a cerebral aneurysm with and without acute aneurysmal subarachnoid hemorrhage | non clinical, involving persons | monocentric | A | PD Dr. / Tilman / Schubert | Zurich University Hospital |
University Hospital Zurich, Dept. of Neuroradiologie, Zurich |
Kantonale Ethikkommission Zürich | 09.05.2023 | ||||||
| 2022-02055 | A Phase 2b Randomized, Double-blind, Active-and Placebo-controlled, Parallel-group, Multicenter Study to Evaluate the Efficacy and Safety of Induction and Maintenance Combination Therapy with Guselkum More ... | clinical trial | drugs | phase 2 | multicentric | C | Prof. Dr. med. Benjamin Misselwitz | Janssen-Cilag International NV |
Inselspital - Bauchzentrum Bern, Bern Intesto, Gastroenterologische Praxis - Crohn-Colitis-Zentrum, Bern Clarunis - Universitäres Bauchzentrum Basel, Universitätsspital Basel, Basel Kantonsspital St. More ... |
Kantonale Ethikkommission Bern | Ethikkommission Nordwest- und Zentralschweiz EKNZ, Ethikkommission Ostschweiz (EKOS), Kantonale Ethikkommission Bern, Kantonale Ethikkommission Zürich | 08.08.2023 | |||
| 2022-02054 | Applicability of Artificial Intelligence for Detection and Quantification of Intraretinal Fluid overlying Retinal Pigment Atrophy on OCT images of Patients with Age-Related Macular Degeneration | personal data/biological material | monocentric | Prof. Dr. med. Stephan Michels | Augenklinik Zürich West |
Augenklinik Zürich West, Zürich |
Kantonale Ethikkommission Zürich | 16.12.2022 | |||||||
| 2022-02053 | A Phase 2b Randomized, Double-blind, Active-and Placebo-controlled, Parallel-group, Multicenter Study to Evaluate the Efficacy and Safety of Induction and Maintenance Combination Therapy with Guselkum More ... | clinical trial | drugs | phase 2 | multicentric | C | Prof. Dr. med. Benjamin Misselwitz | Janssen-Cilag International NV |
Inselspital - Bauchzentrum Bern, Bern Intesto, Gastroenterologische Praxis - Crohn-Colitis-Zentrum, Bern Clarunis – Universitäres Bauchzentrum Basel; Universitätsspital Basel, Basel Kantonsspital St. More ... |
Kantonale Ethikkommission Bern | Ethikkommission Nordwest- und Zentralschweiz EKNZ, Ethikkommission Ostschweiz (EKOS), Kantonale Ethikkommission Bern, Kantonale Ethikkommission Zürich | 08.08.2023 | |||
| 2022-02052 | Parental Reported Outcome Measures (PROMs) after Surgery for Single-Suture Craniosynostosis | non clinical, involving persons | monocentric | A | Dr. med. Dr. med. dent. Benito Benitez | Universitätsspital Basel |
Universitätsspital Basel, 4031, Basel |
Ethikkommission Nordwest- und Zentralschweiz EKNZ | 04.01.2023 | yes | |||||