BASEC ID Project title Type of project Type of clinical trial Study phase (clinical trials only) multi- / monocentric Category Principal investigator Sponsor Investigational sites Lead EC Local EC(s) Approval date Minors Study Ended
2021-01269 Gait performance and cognitive decline in community-dwelling older adults: a post-hoc analysis of the DO-HEALTH Basel cohort personal data/biological material monocentric Dr. med. Stephanie A. Bridenbaugh Universitäre Altersmedizin FELIX PLATTER Universitäre Altersmedizin FELIX PLATTER, Basel
Ethikkommission Nordwest- und Zentralschweiz EKNZ 21.07.2021
2021-01268 Voxel-based lesion symptom mapping in minor acute ischemic stroke with mild baseline symptoms treated with acute stroke therapy personal data/biological material monocentric PD Dr. med. MSc Mirjam Heldner Department of Neurology, Bern
Kantonale Ethikkommission Bern 06.01.2022
2021-01266 Value of monochromatic CT images versus polychromatic conventional CT images for the detection of acute bowel ischemia (ABI) personal data/biological material monocentric Professor Sabine Schmidt Kobbe CHUV - Radiodiagnostic et CHUV, Lausanne
Commission cantonale d'Éthique de la Recherche sur l'être humain Vaud (CER-VD) 26.08.2021
2021-01265 Diagnostic accuracy of regional body composition indices by dual-energy X-ray absorptiometry for lipedema detection: a case-control study in a Swiss University Hospital. personal data/biological material monocentric Ms Lucia Mazzolai CHUV - Angiologie CHUV, Lausanne
Commission cantonale d'Éthique de la Recherche sur l'être humain Vaud (CER-VD) 14.10.2021 Study has ended
2021-01264 Alignment in ORIGIN® knee prostheses non clinical, involving persons monocentric A Prof. Dr. med. Markus P. Arnold Praxis MEIN KNIE Praxis MEIN KNIE, Münchenstein
Ethikkommission Nordwest- und Zentralschweiz EKNZ 07.12.2021
2021-01263 Patient-and Significant Informal Caregiver-Reported Experience Measures following discharge from the Valais Hospital during the second wave of the COVID-19 pandemic non clinical, involving persons monocentric A Mrs Nadine Tacchini-Jacquier Hôpital du Valais Valais Hospital, Sion
Commission cantonale d'Éthique de la Recherche sur l'être humain Vaud (CER-VD) 20.07.2021
2021-01262 Studying the impact of a low carbohydrate diet on the small intestinal microbiota clinical trial other clinical trials monocentric A Prof. Dr. med. Benjamin Misselwitz Universitätsklinik für Viszerale Chirurgie und Medizin Inselspital Bern, Bern
Kantonale Ethikkommission Bern 19.08.2021
2021-01261 Long-term quality of life outcomes after gastric band removal and concomitant gastric bypass: A single centre cohort study. personal data/biological material monocentric med. pract. Matthias Pfister Kantonsspital Frauenfeld STGAG, Kantonsspital Frauenfeld, Frauenfeld
Ethikkommission Ostschweiz (EKOS) 10.06.2021
2021-01260 Health Status and Healthcare Services Utilization among Unaccompanied Asylum-Seeking Minors Settled in Switzerland: Protocol for a Retrospective Cohort Study from a Hospital-based Youth Outpatient Cli More ... personal data/biological material monocentric Dre Magdalini PATSEADOU Consultation Santé Jeunes, HUG Consultation Santé Jeunes, HUG & Institut Universitaire de Médecine de Famille et de l'Enfance (UniGe), Geneva
Commission Cantonale d'éthique de la recherche Genève (CCER) 09.08.2021
2021-01259 Abdominal or Transanal TME in Therapy of Rectal Cancer: A Retrospective Cohort Study personal data/biological material monocentric Dr. med. Lukas Marti Klinik für Chirurgie, Kantonsspital St. Gallen Klinik für Chirurgie, Kantonsspital St. Gallen, St. Gallen
Ethikkommission Ostschweiz (EKOS) 14.06.2021
2021-01258 COAV101A12306 - A Phase IIIb, open-label, single-arm, single-dose, multicenter study to evaluate the safety, tolerability and efficacy of gene replacement therapy with intravenous OAV101 (AVXS-101) in More ... clinical trial drugs phase 3 monocentric C PD Dr. med. Andrea Klein Novartis Pharma Schweiz AG Universitäts-Kinderspital beider Basel, Basel
Ethikkommission Nordwest- und Zentralschweiz EKNZ 16.11.2021 yes Study has ended
2021-01257 FaR-RMS: An overarching study for children and adults with Frontline and Relapsed RhabdoMyoSarcoma clinical trial drugs phase 1/2 multicentric C Dr. med. Willemijn Breunis University of Birmingham Universitäts-Kinderspital Zürich, Zürich
Inselspital Bern, 3010 Bern
Kantonsspital Aarau AG, Aarau
Universitäts-Kinderspital beider Basel (UKBB), 4031 Basel
Luzerner Kantonsspital, Luzern
HUG Hôpitaux More ...
Kantonale Ethikkommission Zürich Ethikkommission Nordwest- und Zentralschweiz EKNZ, Ethikkommission Ostschweiz (EKOS), Kantonale Ethikkommission Bern, Commission cantonale d'Éthique de la Recherche sur l'être humain Vaud (CER-VD), Co More ... 24.08.2021 yes
2021-01256 Does kidney transplantation improve survival in the current era in Europe? personal data/biological material monocentric Prof. Patrice Ambühl ERA-EDTA Registry Institute of Nephrology, Zurich
Kantonale Ethikkommission Zürich 22.12.2021
2021-01255 A phase II, open label, multicenter study to investigate the efficacy and safety of domatinostat in combination with avelumab in patients with treatment-naïve metastatic Merkel Cell Carcinoma - the ME More ... clinical trial drugs phase 2 monocentric C Prof. Dr. med., Dr. sc. nat. Antonio Cozzio 4SC AG Kantonspital St. Gallen; Klinik für Dermatologie, Venerologie und Allergologie, St. Gallen
Ethikkommission Ostschweiz (EKOS) 19.07.2021 Study has ended
2021-01254 Impact de la Iatrogénie médicamenteuse chez les personnes âgées de 75 ans et plus dans le service des Urgences non clinical, involving persons monocentric A Dr. Francois-Xavier AGERON CHUV Centre Hospitalier Universitaire Vaudois, Lausanne
Commission cantonale d'Éthique de la Recherche sur l'être humain Vaud (CER-VD) 21.07.2021
2021-01253 Perception des patients et des infirmières d'orthopédie d’être prêts pour le départ de l’hôpital non clinical, involving persons monocentric A Dr. Sc. Cédric Mabire UNIL - Proline CHUV, Lausanne
Commission cantonale d'Éthique de la Recherche sur l'être humain Vaud (CER-VD) 31.08.2021
2021-01252 MK-3475-B98: A Phase 1b/2 Study to Evaluate the Efficacy and Safety of Pembrolizumab in Combination with Investigational Agents for the Treatment of Participants With PD-1/L1-refractory Extensive-Stag More ... clinical trial drugs phase 1/2 monocentric C Carolin Lips Merck Sharp & Dohme Corp LLC Kantonsspital St. Gallen, St. Gallen
Ethikkommission Ostschweiz (EKOS) 16.09.2021
2021-01251 Development of clinical pupillometry as a tool to grade photoreceptor function for patients with retinal and optic nerve disease non clinical, involving persons monocentric A Aki Kawasaki Hôpital ophtalmique Hôpital Ophtalmique Jules Gonin, Lausanne
Commission cantonale d'Éthique de la Recherche sur l'être humain Vaud (CER-VD) 16.08.2021
2021-01250 Difference of Spatial Contrast Sensitivity in Patients with Cataract and Healthy Controls non clinical, involving persons multicentric A Prof. Lucas Bachmann medignition AG medignition AG, Zürich
Augenmobil, Zürich
Augenarztpraxis Stemmle AG, Zürich
Kantonale Ethikkommission Zürich Kantonale Ethikkommission Zürich 15.10.2021
2021-01249 Comparison of traditional outcome measures and self-assessed goal achievement in patients treated surgically for benign prostatic hyperplasia personal data/biological material monocentric Dr. med. Manolis Pratsinis Klinik für Urologie Klinik für Urologie, Kantonsspital St. Gallen, St. Gallen
Ethikkommission Ostschweiz (EKOS) 17.06.2021