| BASEC ID | Project title | Type of project | Type of clinical trial | Study phase (clinical trials only) | multi- / monocentric | Category | Principal investigator | Sponsor | Investigational sites | Lead EC | Local EC(s) | Approval date | Minors | Study Ended | |
|---|---|---|---|---|---|---|---|---|---|---|---|---|---|---|---|
| 2022-01879 | A Phase 1/2 Study to Evaluate the Safety, Tolerability, and Efficacy of VX-880 in Subjects Who Have Type 1 Diabetes Mellitus with Impaired Hypoglycemic Awareness and Severe Hypoglycemia | clinical trial | transplant products | monocentric | C | Dr. Fadi Haidar | Vertex Pharmaceuticals (Germany) GmbH |
Hospiteaux universitaire Geneve, Geneve |
Commission Cantonale d'éthique de la recherche Genève (CCER) | 25.01.2023 | |||||
| 2022-01878 | Pre‑emptive luminal vacuum drainage (pLVD) of the anastomotic area after upper gastrointestinal tract resection | personal data/biological material | monocentric | Prof. Dr. med. Christian Gutschow | Department of Visceral- and Transplant Surgery, University Hospital Zurich |
UniversitätsSpital Zürich, Zürich |
Kantonale Ethikkommission Zürich | 18.11.2022 | |||||||
| 2022-01877 | A PHASE IB/II RANDOMIZED, OPEN LABEL DRUG REPURPOSING TRIAL OF GLUTAMATE SIGNALING INHIBITORS IN COMBINATION WITH CHEMORADIOTHERAPY IN PATIENTS WITH NEWLY DIAGNOSED GLIOBLASTOMA (GLUGLIO) | clinical trial | drugs | phase 1/2 | multicentric | C | Dr med. Hans-Georg Wirsching | Universitätsspital Zurich |
Universitätsspital Zurich, Zurich Inselspital, University Hospital Bern, Bern University Hospital Basel, Basel Cantonal Hospital Lucerne, Luzerne University of Geneva and Geneva University Hospital, G More ... |
Kantonale Ethikkommission Zürich | Ethikkommission Nordwest- und Zentralschweiz EKNZ, Ethikkommission Ostschweiz (EKOS), Kantonale Ethikkommission Bern, Kantonale Ethikkommission Zürich, Commission cantonale d'Éthique de la Recherche s More ... | 20.12.2022 | |||
| 2022-01876 | MRI-BASED RADIOMICS MODEL FOR PROGNOSTIC PROFILING OF HUMAN PAPILLOMA VIRUS (HPV) DRIVEN CANCERS (OROPHARYNGEAL, CERVICAL AND ANO-GENITAL CANCERS) | personal data/biological material | monocentric | PD dr med Stefania Rizzo |
Ente Ospedaliero Cantonale, Lugano |
Comitato etico cantonale Ticino | 16.01.2023 | ||||||||
| 2022-01875 | Single center comparative study of Kawasaki disease in children before and during the COVID-19 pandemic | personal data/biological material | monocentric | Professeur Nicole Sekarski | CHUV - Cardiogie pédiatrique |
CHUV, Lausanne |
Commission cantonale d'Éthique de la Recherche sur l'être humain Vaud (CER-VD) | 21.02.2023 | |||||||
| 2022-01874 | Assessment of the treatment of keratoconus using customized corneal cross-linking. | clinical trial | other clinical trials | monocentric | A | Prof. Dr. Dr. Farhad Hafezi | ELZA Institute |
ELZA Institute AG, Dietikon |
Kantonale Ethikkommission Zürich | 07.02.2023 | yes | ||||
| 2022-01873 | “To what extend are perceptual deficits caused by ophthalmological factors? An investigation in patients undergoing cataract surgery” | non clinical, involving persons | monocentric | A | Dr. Hanna Zuche | LPSY, BMI, EPFL |
Universitätsspital Basel, Augenklinik, Basel |
Ethikkommission Nordwest- und Zentralschweiz EKNZ | 22.11.2022 | ||||||
| 2022-01872 | Correlation of Anatomic and Measured Specific Knee Footprints using Compressed Lateral and anteroposterior Anatomical Systematic Sequence (“CLASS”) | deceased persons | monocentric | Dr.med. Grégoire Thürig | Department Orthopedic Surgery and Traumatology, HFR cantonal Hospital Fribourg, University of Fribourg |
Orthopädie - HFR, Fribourg |
Commission cantonale d'Éthique de la Recherche sur l'être humain Vaud (CER-VD) | 30.11.2022 | |||||||
| 2022-01871 | Heart Rate Variability, Physical Activity and Exhaustion in the Inpatient Treatment of Stress-Related Disorders - HARMODI. | non clinical, involving persons | monocentric | A | Dr. Thomas Russmann | Department Sport, Exercise and Health, University Basel |
Clinica Holistica Engiadina, Susch |
Kantonale Ethikkommission Zürich | 22.12.2022 | ||||||
| 2022-01870 | Sodium lactate versus Hypertonic Saline Solution in the treatment of intracranial hypertensive episodes in severe brain-injured patients. SLHYSS study | clinical trial | drugs | phase 3 | monocentric | C | Pr Hervé QUINTARD | HUG |
HUG, Gèneve |
Commission Cantonale d'éthique de la recherche Genève (CCER) | 17.01.2023 | ||||
| 2022-01869 | Feasibility study on the use of Redormin® 500 (Ze 91019) on day-time cognition and quality of life in people with occasional sleep problems | clinical trial | drugs | phase 4 | monocentric | B | Dr. Christiane Gerhards | Zeller Medical AG |
University of Basel, Basel |
Ethikkommission Nordwest- und Zentralschweiz EKNZ | 25.11.2022 | Study has ended | |||
| 2022-01868 | An Open-Label Extension Study to Assess the Safety, Tolerability, and Effectiveness of the Long-Term use of Treprostinil Palmitil Inhalation Powder in Participants with Pulmonary Arterial Hypertension | clinical trial | drugs | phase 2 | monocentric | C | Dr Benoît Lechartier | Insmed Switzerland GmbH |
CHUV, Lausanne |
Commission cantonale d'Éthique de la Recherche sur l'être humain Vaud (CER-VD) | 27.01.2023 | ||||
| 2022-01866 | A 2-Part Seamless Part A (Phase 2)/Part B (Phase 3) Randomized, Double-Blind, Placebo-Controlled, Multicenter Study to Evaluate the Efficacy and Safety of BIIB059 in Participants with Active Subacute More ... | clinical trial | drugs | phase 3 | multicentric | C | Prof. Antonio Cozzio | Biogen Idec Research Limited |
Kantonsspital St. Gallen, St. Gallen Centre Hospitalier Universitaire Vaudois (CHUV), Lausanne Universitätsspital Zürich, Zürich |
Ethikkommission Ostschweiz (EKOS) | Kantonale Ethikkommission Zürich, Commission cantonale d'Éthique de la Recherche sur l'être humain Vaud (CER-VD) | 22.12.2022 | |||
| 2022-01863 | Zurich Infant Faces: Development of the Zurich Infant Faces Database for Neutral and Happy Faces | non clinical, involving persons | monocentric | A | Prof.Dr.med Giancarlo Natalucci | University Hospital of Zurich |
University Hospital Zurich/ University of Zurich, Zurich |
Kantonale Ethikkommission Zürich | 27.01.2023 | yes | |||||
| 2022-01862 | Stationary psilocybin-assisted versus treatment as usual psychodynamic psychotherapy for treatment-resistant depression: A qualitative and observational pilot study | non clinical, involving persons | monocentric | A | PD Dr. med. Rainer Krähenmann | Psychiatrische Dienste Thurgau |
Psychiatric Services Thurgau, Münsterlingen |
Ethikkommission Ostschweiz (EKOS) | 29.11.2022 | ||||||
| 2022-01861 | Effect of Glyceroltrinitrate on human energy expenditure and brown adipose tissue thermogenesis | clinical trial | other clinical trials | monocentric | B | PD Dr.med. Matthias J. Betz | University Hospital Basel |
Department of Endocrinology, Diabetes and Metabolism, University Hospital Basel, Basel |
Ethikkommission Nordwest- und Zentralschweiz EKNZ | 03.01.2023 | |||||
| 2022-01860 | Long term outcome in adolescent and young adult treated with Ponseti manipulative technique | non clinical, involving persons | monocentric | A | Ambra Donzelli | BPR |
CHUV, Lausanne |
Commission cantonale d'Éthique de la Recherche sur l'être humain Vaud (CER-VD) | 02.12.2022 | yes | |||||
| 2022-01859 | Boosting and guiding neuroplasticity by combining ketamine with neurofeedback-assisted learning – towards an individualized and integrated pharmaco-psychotherapy for cocaine addiction | clinical trial | drugs | phase 2 | monocentric | B | Dr. med. Marcus Herdener | Psychiatrische Universitätsklinik Zürich |
Psychiatrische Universitätsklinik Zürich, Universität Zürich, Zürich |
Kantonale Ethikkommission Zürich | 06.12.2022 | ||||
| 2022-01858 | Vessel pathology and vascular-device interaction | deceased persons | monocentric | Dr. Max Gay | BIOTRONIK AG |
Biotronik AG, Bülach |
Kantonale Ethikkommission Zürich | 18.08.2023 | |||||||
| 2022-01857 | Individualized cephalometry: an update of the Segner-Hasund harmony box. | personal data/biological material | monocentric | Dr. Vasiliki Koretsi | Klinik für Kieferorthopädie und Kinderzahnmedizin |
Klinik für Kieferorthopädie und Kinderzahnmedizin, Zürich |
Kantonale Ethikkommission Zürich | 18.11.2022 | |||||||