| BASEC ID | Project title | Type of project | Type of clinical trial | Study phase (clinical trials only) | multi- / monocentric | Category | Principal investigator | Sponsor | Investigational sites | Lead EC | Local EC(s) | Approval date | Minors | Study Ended | |
|---|---|---|---|---|---|---|---|---|---|---|---|---|---|---|---|
| 2022-00619 | Novel Long Acting Injectable Antiretrovirals: Real-Life Therapeutic Drug Concentration Monitoring in Switzerland | non clinical, involving persons | multicentric | A | Prof Matthias Cavassini | CHUV |
CHUV, Lausanne HUG, Geneva |
Commission cantonale d'Éthique de la Recherche sur l'être humain Vaud (CER-VD) | Commission Cantonale d'éthique de la recherche Genève (CCER) | 14.07.2022 | |||||
| 2022-00618 | Automatische und patientenspezifische 3D-MRT-Modelle von Hüftknochen, Hüftknorpel und Labrum für verbesserte chirurgische Entscheidungsfindung | personal data/biological material | monocentric | PD Dr. med. Simon D. Steppacher | Inselspital Bern |
Department für Orthopädie und Traumatologie, Inselspital Bern, Bern |
Kantonale Ethikkommission Bern | 13.05.2022 | |||||||
| 2022-00616 | Harnessing the beneficial non-specific effects of measles-mumps-rubella vaccine on infection with unrelated pathogens and allergic diseases in children – a single-centre phase IV randomised controlle More ... | clinical trial | drugs | phase 4 | monocentric | A | Dr Laure PITTET | University Hospital of Geneva |
University Hospitals of Geneva, Geneva |
Commission Cantonale d'éthique de la recherche Genève (CCER) | 19.05.2022 | yes | |||
| 2022-00615 | ‘Quality of life evaluation for patients with rectal cancer having undergone sphincter sparing surgery: evaluation of the low anterior resection syndrome (LARS)’ | non clinical, involving persons | monocentric | A | Prof. Bernhard Egger | HFR Cantonal Hospital of Fribourg |
Department of general surgery, HFR Cantonal Hospital, Fribourg |
Commission cantonale d'Éthique de la Recherche sur l'être humain Vaud (CER-VD) | 30.09.2022 | ||||||
| 2022-00614 | Comparaison du Bioactive Glass avec d’autres substituts osseux : autogreffe, allogreffe et antibiotiques locaux dans le traitement des pseudarthroses et ostéomyélites : une étude rétrospective. | personal data/biological material | monocentric | MD, PD, MERc Sylvain Steinmetz | CHUV |
CHUV, Lausanne |
Commission cantonale d'Éthique de la Recherche sur l'être humain Vaud (CER-VD) | 26.04.2022 | |||||||
| 2022-00613 | A randomized, placebo-controlled, double-blind, monocenter, phase II trial to assess the efficacy of Calcium Dobesilate (CaD) vs. placebo on SARS-CoV-2 viral load amongst outpatients with COVID-19 | clinical trial | drugs | phase 2 | monocentric | B | MD Hervé Spechbach | Hôpitaux universitaire de Genève (HUG) |
Hôpitaux universitaire de Genève (HUG), Geneva |
Commission Cantonale d'éthique de la recherche Genève (CCER) | 17.05.2022 | yes | |||
| 2022-00611 | Geschlechterspezifische Unterschiede in den Ursachen von Synkopen | personal data/biological material | monocentric | PD Dr. med. Dr. phil. Ksenija Slankamenac | Institut für Notfallmedizin |
Institut für Notfallmedizin, Zürich |
Kantonale Ethikkommission Zürich | 08.04.2022 | Study has ended | ||||||
| 2022-00610 | Biological behavior of sparsely and densely granulated GH secreting pituitary adenomas: a retrospective observational study of surgical series | personal data/biological material | monocentric | Dr Giulia Cossu | CHUV |
CHUV, Lausanne |
Commission cantonale d'Éthique de la Recherche sur l'être humain Vaud (CER-VD) | 28.04.2022 | |||||||
| 2022-00609 | Comparison Of Accuracy Of Conventional Plating Vs. Intercus Plate In CARD Opening-Wedge Osteotomies Of Distal Radius Malunion | personal data/biological material | monocentric | Prof. Dr. med. Anderas Schweizer | Universitätsklinik Balgrist |
Universitätsklinik Balgrist, Zürich |
Kantonale Ethikkommission Zürich | 12.04.2022 | |||||||
| 2022-00608 | A Randomized, Double-blind, Placebo-controlled, Repeat-dose, Multicenter Trial to Evaluate the Efficacy, Safety, Tolerability and Pharmacokinetics of HZN-825 in Patients with Diffuse Cutaneous Systemi More ... | clinical trial | drugs | phase 2 | multicentric | C | Prof. Dr. Britta Maurer | Horizon Therapeutics Ireland DAC |
Inselspital Bern Anna Seiler Haus, Stock A Zimmer 315, Freiburgstrasse 18, 3010 Bern, Bern Kantonsspital St. Gallen, Klinik für Rheumatologie, St. Gallen HFR Fribourg - Hôpital cantonal, Department of More ... |
Kantonale Ethikkommission Bern | Ethikkommission Ostschweiz (EKOS), Commission cantonale d'Éthique de la Recherche sur l'être humain Vaud (CER-VD) | 28.11.2022 | |||
| 2022-00607 |
Efficacy of an unguided or guided app-based psychosocial intervention to enhance quality of life in Arabic-speaking refugees residing in Switzerland: A randomized controlled trial |
clinical trial | other clinical trials | monocentric | A | Prof. Dr. Thomas Berger | Universität Bern |
University of Bern, Institute of Psychology, Bern |
Kantonale Ethikkommission Bern | 08.08.2022 | |||||
| 2022-00606 | Personalized IMMUNOtherapy in SEPsis: A multicentre and multinational, double-blind, double-dummy randomized clinical trial | clinical trial | drugs | phase 2 | monocentric | C | Prof. Thierry Calandra | Hellenic Institute for the Study of Sepsis |
CHUV, Lausanne |
Commission cantonale d'Éthique de la Recherche sur l'être humain Vaud (CER-VD) | 01.06.2022 | ||||
| 2022-00605 | SERENA-4: A Randomised, Multicentre, Double-Blind, Phase III Study of AZD9833 (an Oral SERD) plus Palbociclib versus Anastrozole plus Palbociclib for the Treatment of Patients with Estrogen Receptor-P More ... | clinical trial | drugs | phase 3 | multicentric | C | PD Dr. med Marcus Vetter | AstraZeneca AB |
Kantonsspital Baselland, Onkologie Hämatologie & Immuntherapie, 4410 Liestal Inselspital, Universitätsspital Bern, Freiburgstrasse 15, 3010 Bern Brust-Zentrum Zürich, Onkologie, Zürich |
Ethikkommission Nordwest- und Zentralschweiz EKNZ | Kantonale Ethikkommission Bern, Kantonale Ethikkommission Zürich | 20.07.2022 | |||
| 2022-00604 | Controllability and the interoception of breathing (CITRO) | non clinical, involving persons | monocentric | A | Dr. Sandra Iglesias, PhD | UZH & ETHZ, Institut für Biomedizinische Technik, Translational Neuromodeling Unit |
Translational Neuromodeling Unit, Zurich |
Kantonale Ethikkommission Zürich | 06.05.2022 | ||||||
| 2022-00603 | SASCIA - Phase III postneoadjuvant study evaluating Sacituzumab Govitecan, an Antibody Drug Conjugate in primary HER2-negative breast cancer patients with high relapse risk after standard neoadjuvant More ... | clinical trial | drugs | phase 3 | multicentric | C | Dr. med. Ursina Zürrer | GBG (German Breast Group) |
Kantonsspital Winterthur, Winterthur Brustzentrum, University Hospital Basel, Basel Kantonsspital St. Gallen, St. Gallen Brustzentrum Zürich, Zürich Kantonsspital Graubünden, Chur |
Kantonale Ethikkommission Zürich | Ethikkommission Nordwest- und Zentralschweiz EKNZ, Ethikkommission Ostschweiz (EKOS), Kantonale Ethikkommission Zürich | 24.06.2022 | |||
| 2022-00602 | A brief report of an interesting bone marrow finding in systemic mastocytosis | personal data/biological material | monocentric | Dr Vasiliki Papadopoulou | CHUV |
CHUV, Lausanne |
Commission cantonale d'Éthique de la Recherche sur l'être humain Vaud (CER-VD) | 07.04.2022 | Study has ended | ||||||
| 2022-00600 |
Phase IIb, randomized, double-blind, placebo-controlled study in parallel groups assessing the efficacy and safety of two doses of SOM3355 in patients suffering from Huntington’s Disease with ch More ... |
clinical trial | drugs | phase 2 | monocentric | C | Michael Orth | SOM Innovation Biotech S.A. |
Neurozentrum Siloah, Gumlingen |
Kantonale Ethikkommission Bern | 03.02.2023 | ||||
| 2022-00597 | Evaluation of molecular and Next Generation Sequencing approaches for SARS-CoV-2 identification and characterization in clinical samples | personal data/biological material | monocentric | PD Dr. Alban Ramette | University of Bern |
University of Bern, Bern |
Kantonale Ethikkommission Bern | 15.09.2022 | |||||||
| 2022-00595 | Streptococcus bovis bacteraemia : metastatic malignancies in the gut are also a gateway | personal data/biological material | monocentric | Sylvain Meylan | CHUV |
CHUV, Lausanne |
Commission cantonale d'Éthique de la Recherche sur l'être humain Vaud (CER-VD) | 19.04.2022 | Study has ended | ||||||
| 2022-00594 | Fontan-associated Liver Disease (FALD): laboratory, clinical, histological and imaging characteristics of a Swiss, single-centre, adult cohort | personal data/biological material | monocentric | Prof. Annalisa Berzigotti | UVCM, Hepatology |
UVCM, Inselspital, Bern |
Kantonale Ethikkommission Bern | 09.12.2022 | |||||||