| BASEC ID | Project title | Type of project | Type of clinical trial | Study phase (clinical trials only) | multi- / monocentric | Category | Principal investigator | Sponsor | Investigational sites | Lead EC | Local EC(s) | Approval date | Minors | Study Ended | |
|---|---|---|---|---|---|---|---|---|---|---|---|---|---|---|---|
| 2023-01033 | Companion Diagnostic: Clinical Performance Study Plan for Ki-67 IHC MIB-1 pharmDx (Dako Omnis) on early breast cancer specimens used to identify subjects for enrolment in AstraZeneca's Phase III CAMBR More ... | personal data/biological material | monocentric | Claire Begot | AstraZeneca |
Labcorp CLS, Meyrin |
Commission Cantonale d'éthique de la recherche Genève (CCER) | 19.06.2023 | |||||||
| 2023-01032 | Reliability and agreement between radiologists and an AI language model in the BI-RADS categorization of BI-RADS lexicon items | personal data/biological material | monocentric | Dr. Simone Schiaffino | Ente Ospedaliero Cantonale |
Ente Ospedaliero Cantonale, Lugano |
Comitato etico cantonale Ticino | 14.06.2023 | |||||||
| 2023-01031 | Companion Diagnostic: Clinical Performance Study Protocol for SK035 Claudin 18.2 IHC pharmDx and SK005 PD-L1 IHC 28-8 pharmDx on Gastric or Gastroesophageal Junction (Gastric/GEJ) Adenocarcinoma. | personal data/biological material | monocentric | Dr. Paul Mesange | Transcenta Suzhou |
Labcorp CLS, Meyrin |
Commission Cantonale d'éthique de la recherche Genève (CCER) | 12.06.2023 | |||||||
| 2023-01030 |
TAXONOMY, TREATMENT, TARGETS AND REMISSION: 3TR-SLE-Study |
non clinical, involving persons | monocentric | A | Prof. Dr. med. Anne-Katrin Pröbstel | GENYO/Pfizer |
University Hospital of Basel, Basel |
Ethikkommission Nordwest- und Zentralschweiz EKNZ | 14.08.2023 | ||||||
| 2023-01029 | Psychological symptoms and treatment for patients with cardiovascular disease | non clinical, involving persons | monocentric | A | Dr. phil. Sven Schmutz | University Hospital Bern, Inselspital |
University Hospital Bern, Inselspital, Bern |
Kantonale Ethikkommission Bern | 18.09.2023 | ||||||
| 2023-01028 | Two-part, first-in-human study on ODM-212 in subjects with selected advanced solid tumours | clinical trial | drugs | phase 1/2 | monocentric | C | Dr. med. Ilaria Colombo | Orion Corporation |
Istituto Oncologico della Svizzera Italiana - IOSI, Bellinzona |
Comitato etico cantonale Ticino | 28.08.2023 | ||||
| 2023-01027 | Safety and efficacy in long-term treatment with rituximab in myasthenia gravis patients: experience from tertiary referral centers in Switzerland and France | personal data/biological material | multicentric | Dre. Agustina M. Lascano, PhD, PD | Hôpitaux Universitaires de Genève |
Hôpitaux Universitaires de Genève, Genève CHUV, Lausanne |
Commission Cantonale d'éthique de la recherche Genève (CCER) | Commission cantonale d'Éthique de la Recherche sur l'être humain Vaud (CER-VD) | 17.09.2024 | ||||||
| 2023-01026 | Protocollo di studio per la definizione delle competenze e delle attività di un ruolo di infermiere di pratica avanzata (advanced practice nurse) all’interno del team interprofessionale dello Stroke C More ... | non clinical, involving persons | monocentric | A | Corina Elena Luca | Ente Ospedaliero Cantonale |
Ente Ospedaliero Cantonale, Lugano |
Comitato etico cantonale Ticino | 03.07.2023 | ||||||
| 2023-01025 | Analysis of volatile organic compounds in patients with type 1 diabetes in induced hypoglycaemia with a breath analyser | personal data/biological material | monocentric | Prof. Dr. Lilian Witthauer | University of Bern |
University of Bern, Switzerland |
Kantonale Ethikkommission Bern | 21.06.2023 | Study has ended | ||||||
| 2023-01024 | Registry on cardiac sarcoidosis and inflammatory disease | personal data/biological material | monocentric | Dr. Valentina A. Rossi |
University Heart Centre, University Hospital of Zurich, Zurich |
Kantonale Ethikkommission Zürich | 30.08.2023 | ||||||||
| 2023-01023 | Swiss pilot screening study for unruptured intracranial aneurysms to prevent subarachnoid hemorrhage in smokers | non clinical, involving persons | monocentric | A | PD Dr. med. Johannes Goldberg | Universitätsklinik für Neurochirurgie |
Universitätsklinik für Neurochirurgie, Bern |
Kantonale Ethikkommission Bern | 28.07.2023 | ||||||
| 2023-01022 | Recurrence ad survival after robotic versus laparoscopic liver resection in very-early to early (BCLC 0-A) hepatocellular carcinoma | personal data/biological material | monocentric | Dr.med Alessandra Cristaudi | EOC |
EOC, Lugano |
Comitato etico cantonale Ticino | 14.08.2023 | Study has ended | ||||||
| 2023-01021 |
Baseline features and outcome of patients with brain metastases from solid tumors. A retrospective single center experience. |
personal data/biological material | monocentric | Prof. Dr. med. Anastasios Stathis | Instituto Oncologico della Svizzera Italiana (IOSI) |
IOSI, Bellinzona |
Comitato etico cantonale Ticino | 15.06.2023 | |||||||
| 2023-01020 | Effects of acute exercise on experimental pain response and GABAergic signaling according to intensive regular training and chronic pain contexts: a multiple case study | non clinical, involving persons | monocentric | A | Dr Joelle N. Chabwine | UNIFR - Médecine |
University of Fribourg, Fribourg |
Commission cantonale d'Éthique de la Recherche sur l'être humain Vaud (CER-VD) | 02.11.2023 | ||||||
| 2023-01018 | Identification of the molecular mechanisms of non-response to treatments, relapses and remission in multiple sclerosis | non clinical, involving persons | monocentric | A | Prof.Dr.med.anne-Katrin Pröbstel | GENYO/Pfizer |
University Hospital Basel, Basel |
Ethikkommission Nordwest- und Zentralschweiz EKNZ | 15.08.2023 | ||||||
| 2023-01017 | Scapholunate ligament reconstruction: early dart throwing motion versus motion in anatomical planes | clinical trial | other clinical trials | monocentric | A | PD Dr. med. L. Reissner | Univeristätsklinik Balgrist |
Universitätsklinik Balgrist, Zürich |
Kantonale Ethikkommission Zürich | 15.09.2023 | |||||
| 2023-01016 | Orchestra in Class, a novel booster for executive functions and brain development in young primary school children | clinical trial | other clinical trials | monocentric | A | Prof. Dr. Clara James | University of Applied Sciences and Arts Western Switzerland HES-SO |
Haute école de santé de Genève HES-SO, 1206 Genève |
Commission Cantonale d'éthique de la recherche Genève (CCER) | 04.07.2023 | yes | ||||
| 2023-01015 | A retrospective analyzis of patients with Revitan revision hip prosthesis fracture, a comparison to the literature and a technical description of how to change a fractured Revitan stem | personal data/biological material | monocentric | Dr. med. PhD Karl Grob | Kantonsspital St.Gallen, Orthopädie und Traumatologie |
Kantonsspital St. Gallen, Klinik für Orthopädische Chirurgie und Traumatologie des Bewegungsapparates, St. Gallen |
Ethikkommission Ostschweiz (EKOS) | 01.06.2023 | |||||||
| 2023-01014 | Immediate implant placement versus alveolar ridge preservation with delayed implant placement: a randomized controlled clinical trial on patient-reported outcome measures | clinical trial | other clinical trials | monocentric | A | Prof.Dr. Daniel Thoma | University of Zurich |
University of Zürich, Zürich |
Kantonale Ethikkommission Zürich | 25.07.2023 | |||||
| 2023-01013 | Upwards Initial Adjustment of Wide-Spectrum Antibiotic Dosage in Pediatric Oncology Patients with Febrile Neutropenia and Suspected Augmented Renal Clearance : A Randomized Controlled Trial with Thera More ... | clinical trial | drugs | phase 4 | monocentric | A | Dr Pierre-Alex Crisinel | CHUV Centre Hospitalier Universitaire Vaudois |
CHUV, Lausanne |
Commission cantonale d'Éthique de la Recherche sur l'être humain Vaud (CER-VD) | 24.07.2023 | yes | |||