| BASEC ID | Project title | Type of project | Type of clinical trial | Study phase (clinical trials only) | multi- / monocentric | Category | Principal investigator | Sponsor | Investigational sites | Lead EC | Local EC(s) | Approval date | Minors | Study Ended | |
|---|---|---|---|---|---|---|---|---|---|---|---|---|---|---|---|
| 2022-01742 | A pilot study on home treatment for individuals suffering from severe addictive disorders | clinical trial | other clinical trials | monocentric | A | Dr Louise Penzenstadler | Hôpitaux Universitaires Genève |
Hôpitaux Universitaires Genève, Genève |
Commission Cantonale d'éthique de la recherche Genève (CCER) | 19.12.2022 | |||||
| 2022-01740 | Pre-amputation assessment of the extent of infected bone in diabetic foot osteomyelitis with the 7-Tesla MRI - a pilot evaluation | clinical trial | other clinical trials | monocentric | B | PD Dr. med. Felix Waibel | Universitätsklinik Balgrist |
Universitätsklinik Balgrist, Zürich |
Kantonale Ethikkommission Zürich | 21.10.2022 | |||||
| 2022-01739 | Schätzung des intrauterinen kindlichen Gewichts mittels abdominaler Palpation und Ultraschallbiometrie in einem Schweizer Zentrumsspital - eine vergleichende, diagnostische Validitäts-Studie | personal data/biological material | monocentric | Prof. Dr. Susanne Grylka |
Zürcher Fachhochschule für angewandte Wissenschaft, 8840 Winterthur |
Ethikkommission Nordwest- und Zentralschweiz EKNZ | 22.11.2022 | ||||||||
| 2022-01738 | Analyse comparative rétrospective des paramètres du ROTEM sigma avec les tests de laboratoire standards afin de déterminer les valeurs seuil ROTEM optimales de substitution hémostatique dans le contex More ... | personal data/biological material | monocentric | Dre Emmanuelle Scala | CHUV - Anesthésiologie |
CHUV, Lausanne |
Commission cantonale d'Éthique de la Recherche sur l'être humain Vaud (CER-VD) | 25.11.2022 | |||||||
| 2022-01737 |
CABL001J12302 - A phase IIIb, multi-center, open-label, randomized study of tolerability and efficacy of oral asciminib versus nilotinib in patients with newly diagnosed Philadelphia Chromosome Posi More ... |
clinical trial | drugs | phase 3 | monocentric | C | Prof. Yves Chalandon | Novartis Pharma Schweiz AG |
HUG, Geneve |
Commission Cantonale d'éthique de la recherche Genève (CCER) | 27.03.2023 | ||||
| 2022-01736 | Initial Covid-19 mitigation measures in 2020 and preterm birth, low birth weight and mode of delivery in Switzerland: difference-in-differences analyses based on the statistics of independent midwifes | personal data/biological material | monocentric | Dr. Marlene Rauch | Basel Pharmacoepidemiology Unit |
Basel Pharmacoepidemiology Unit, Basel |
Ethikkommission Nordwest- und Zentralschweiz EKNZ | 09.11.2022 | |||||||
| 2022-01735 | Cell-free DNA based biomarker detection for personalized cancer monitoring | personal data/biological material | monocentric | Prof. Michael Krauthammer | Universität Zürich |
Institut für Quantitative Biomedizin, Zürich |
Kantonale Ethikkommission Zürich | 17.01.2023 | |||||||
| 2022-01734 | A Randomized, Multicenter, Open-label, Phase III Study of Lurbinectedin Single-Agent or Lurbinectedin in Combination with Irinotecan versus Investigator’s Choice (Topotecan or Irinotecan) in Relapsed More ... | clinical trial | drugs | phase 3 | multicentric | C | Dr. Hasna Bouchaab | PharmaMar S.A. |
Centre Hospitalier Universitaire Vaudois, Lausanne Kantonspital Baselland, Baselland University Hospital Basel, Basel Spital Thurgau AG, Munsterlingen / Frauenfeld Istituto Oncologico della Svizzera I More ... |
Commission cantonale d'Éthique de la Recherche sur l'être humain Vaud (CER-VD) | Ethikkommission Nordwest- und Zentralschweiz EKNZ, Ethikkommission Ostschweiz (EKOS), Commission cantonale d'Éthique de la Recherche sur l'être humain Vaud (CER-VD), Comitato etico cantonale Ticino | 17.07.2023 | |||
| 2022-01733 | Long-term outcome of patients treated with a leadless pacemaker (MICRA) in Switzerland | personal data/biological material | multicentric | Dr. med. Tardu Özkartal | Cardiocentro Institute Ticino - EOC |
Cardiocentro Institute Ticino, Lugano Universitätsspital Bern, Bern Universitätsspital Basel, Basel Kantonsspital Luzern, Luzern Kantonsspital St. Gallen, St. Gallen Universitätsspital Zürich, Zürich |
Comitato etico cantonale Ticino | Ethikkommission Nordwest- und Zentralschweiz EKNZ, Ethikkommission Ostschweiz (EKOS), Kantonale Ethikkommission Bern, Kantonale Ethikkommission Zürich | 16.03.2023 | ||||||
| 2022-01732 | Association between left-ventricular unloading during extracorporeal cardio-pulmonary resuscitation in patients with cardiac arrest caused by acute myocardial infarction on 30-day mortality. | personal data/biological material | monocentric | Prof. Dr. | Charité – University Hospital Berlin |
Universitätsspital Zürich USZ, Zürich |
Kantonale Ethikkommission Zürich | 11.07.2023 | |||||||
| 2022-01728 | Evolution of growth following anti-TNFα therapy in paediatric Crohn’s disease. | personal data/biological material | monocentric | Dr Andreas Nydegger | CHUV - DFME |
CHUV, Lausanne |
Commission cantonale d'Éthique de la Recherche sur l'être humain Vaud (CER-VD) | 05.01.2023 | |||||||
| 2022-01726 | Predictability of astigmatism correction by arcuate incisions with a femtosecond laser using the Gauss approximation calculation. | personal data/biological material | monocentric | Prof. Dr. med. Bojan Pajic |
Orasis Augenklinik, Reinach AG |
Ethikkommission Nordwest- und Zentralschweiz EKNZ | 02.11.2022 | Study has ended | |||||||
| 2022-01725 | Retrospective study: Assessment of the suitability of the newborn screening for the prevention of an alimentary vitamin B12 deficiency in infancy. | personal data/biological material | multicentric | Prof. Dr. Martina Huemer |
Kinderspital Zürich, Zürich Inselspital Bern, Bern University Children’s Hospital Basel (UKBB), Basel Kantonsspital Aarau AG Kinderspital, Aarau Luzerner Kantonsspital Kinderspital, Luzern Ostschweize More ... |
Kantonale Ethikkommission Zürich | Ethikkommission Nordwest- und Zentralschweiz EKNZ, Ethikkommission Ostschweiz (EKOS), Kantonale Ethikkommission Bern, Kantonale Ethikkommission Zürich | 16.02.2024 | |||||||
| 2022-01724 | MK-6598-001: A Phase 1, Open-label, Multicenter Study to Assess Safety, Tolerability, PK, and Efficacy of MK-6598 as Monotherapy and in Combination With Pembrolizumab in Participants With Advanced Sol More ... | clinical trial | drugs | phase 1 | multicentric | C | PD Dr. med. Anastasios Stathis | Merck Sharp & Dohme Corp. Whitehouse Station, NJ (USA) |
Istituto Oncologico della Svizzera Italiana (IOSI), Bellinzona Hôpitaux Universitaires de Genève (HUG), Genève Kantonsspital St. Gallen, St. Gallen |
Comitato etico cantonale Ticino | Ethikkommission Ostschweiz (EKOS), Commission Cantonale d'éthique de la recherche Genève (CCER) | 13.12.2022 | |||
| 2022-01722 |
Mucosal Immunity: Influence on Infectious Viral Load: a prospective observational study |
non clinical, involving persons | monocentric | A | Prof. Isabella Eckerle | University Hospital of Geneva |
University Hospitals of Geneva, Geneva |
Commission Cantonale d'éthique de la recherche Genève (CCER) | 19.12.2022 | ||||||
| 2022-01721 | Kardiale Gewebespende und Homograftgewinnung | personal data/biological material | monocentric | Dr med. Martin O. Schmiady | USZ |
USZ, Zürich |
Kantonale Ethikkommission Zürich | 18.10.2022 | |||||||
| 2022-01720 | OPtimisation of antiviral Therapy in Immunocompromised COVID-19 patients: a randomized factorial controlled strategy trial | clinical trial | drugs | phase 2 | multicentric | A | Prof. Alexandra Calmy | Geneva University Hospitals |
HUG, Geneva University of Basel, Department Biomedicine, Basel CHUV, Lausanne Zurich University Hospital, Zurich |
Commission Cantonale d'éthique de la recherche Genève (CCER) | Ethikkommission Nordwest- und Zentralschweiz EKNZ, Kantonale Ethikkommission Zürich, Commission cantonale d'Éthique de la Recherche sur l'être humain Vaud (CER-VD) | 31.10.2022 | |||
| 2022-01719 | Pediatric Acute Asthma Management in the Emergency Department and Associated Outcomes: A Pediatric Emergency Research Network Study (Global Asthma Study) | personal data/biological material | multicentric | PD Dr. med. Michelle Seiler | University Children's Hospital Zurich |
University Children's Hospital Zurich, Zurich Inselspital, Bern |
Kantonale Ethikkommission Zürich | Kantonale Ethikkommission Bern | 18.10.2022 | ||||||
| 2022-01718 | A Pilot Study to Assess the Feasibility of Non-Invasive, Transcutaneous Glucose Measurement | non clinical, involving persons | monocentric | A | Fabien Rebeaud, Ph.D. | Spiden AG |
Spiden AG, Pfaeffikon SZ |
Ethikkommission Nordwest- und Zentralschweiz EKNZ | 25.10.2022 | ||||||
| 2022-01716 | Artificial Intelligence for the immune profiling of Hepatocellular carcinoma. | personal data/biological material | monocentric | Dr Antonia Digklia | Henri Mondor University Hospital |
chuv, Lausanne |
Commission cantonale d'Éthique de la Recherche sur l'être humain Vaud (CER-VD) | 08.11.2022 | |||||||