| BASEC ID | Project title | Type of project | Type of clinical trial | Study phase (clinical trials only) | multi- / monocentric | Category | Principal investigator | Sponsor | Investigational sites | Lead EC | Local EC(s) | Approval date | Minors | Study Ended | |
|---|---|---|---|---|---|---|---|---|---|---|---|---|---|---|---|
| 2021-01200 |
Paroxysmal Nocturnal Hemoglobinuria (PNH) Registry [Register für paroxysmale nächtliche Hämoglobinurie (PNH)] |
non clinical, involving persons | monocentric | A | Dr. med. Marina Bissig | Alexion Pharmaceuticals, Inc. |
Universitätsspital Zürich, Zürich |
Kantonale Ethikkommission Zürich | 20.07.2021 | yes | |||||
| 2021-01199 | Effects of the Covid-19 Pandemic on clinical outcomes of patients with malnutrition included in the EFFORT trial | personal data/biological material | monocentric | Prof. Dr. med. Philipp Schütz | Kantonsspital Aarau |
Kantonsspital Aarau, Medizinische Universitätsklinik, Aarau |
Ethikkommission Nordwest- und Zentralschweiz EKNZ | 29.06.2021 | |||||||
| 2021-01198 |
A Phase 3 Open-Label, Randomized Study of LOXO-305 versus Investigator Choice of BTK Inhibitor in Patients with Previously Treated BTK Inhibitor Naïve Mantle Cell Lymphoma (BRUIN MCL-321) |
clinical trial | drugs | phase 3 | multicentric | C | Dr. med. Thilo Zander | Loxo Oncology Inc |
Luzerner Kantonsspital, Luzern Istituto Oncologico della Svizzera Italiana (IOSI), Bellinzona |
Ethikkommission Nordwest- und Zentralschweiz EKNZ | Comitato etico cantonale Ticino | 30.08.2021 | |||
| 2021-01197 | Communication clinique à l’hôpital avec les patients âgés et leurs proches dans le contexte des mesures de prévention et de gestion du Covid-19 | non clinical, involving persons | monocentric | A | Sterie Anca | CHUV - Soins palliatifs gériatriques |
CHUV, Lausanne |
Commission cantonale d'Éthique de la Recherche sur l'être humain Vaud (CER-VD) | 14.10.2021 | ||||||
| 2021-01196 | FAROS (Functionally Accurate Robotic Surgery) in spinal Surgery: Sensor data collection for deep learning, development of metrics and validation of an autonomous robot in spinal surgery | deceased persons | monocentric | Prof. Philipp Fürnstahl | Universitätsklinik Balgrist |
Universitätsklinik Balgrist, Zürich |
Kantonale Ethikkommission Zürich | 15.06.2021 | |||||||
| 2021-01195 | Relationship between delayed verbal episodic memory performance and brain morphometry in patients with acquired brain lesions | personal data/biological material | monocentric | Dr. phil. Martina Studer | Inselspital |
Universitätsklinik für Neurologie, Inselspital, 3010 Bern |
Kantonale Ethikkommission Bern | 14.07.2021 | |||||||
| 2021-01194 | The management of tuboovarian abscess: a single center cohort study | personal data/biological material | monocentric | Dr. med. Konstantinos Nirgianakis | Universitätsklinik für Frauenheilkunde, Inselspital |
Universitätsklinik für Frauenheilkunde, Inselspital, Bern |
Kantonale Ethikkommission Bern | 25.10.2021 | |||||||
| 2021-01192 |
Long-term Results after ReveL Osteotomy for Hallux valgus -Risk factors for recurrence after a minimum follow-up of 10 years |
non clinical, involving persons | monocentric | A | Dr. med. Lizzy Weigelt | Universitätsklinik Balgrist |
Universitätsklinik Balgrist, Zürich |
Kantonale Ethikkommission Zürich | 20.07.2021 | ||||||
| 2021-01191 | Posterior fossa lesions surgery and ventricular dilatation : multicenter retrospective study for the identification of risk factors for postoperative hydrocephalus development and evaluation of actual More ... | personal data/biological material | monocentric | Pr. Karl Schaller | Fondazione IRCCS istituto Neurologico Nazionale |
HUG, Geneva |
Commission Cantonale d'éthique de la recherche Genève (CCER) | 14.09.2021 | |||||||
| 2021-01190 | Clitoral Reconstruction (CR) in FGM/C Patients: Assessment of Multidisciplinary Care | non clinical, involving persons | monocentric | A | PD Dr. med Jasmin Abdulcadir | Universitätsspital Basel |
Hôpitaux Universitaires de Genève, Genève |
Commission Cantonale d'éthique de la recherche Genève (CCER) | 20.07.2021 | ||||||
| 2021-01189 | Comparison of factors impacting liver growth after regenerative liver procedures: a retrospective analysis based on a multicenter HPB register database | personal data/biological material | monocentric | Ass. prof. of surgery Erik Schadde | Department of Visceral and Thoracic Surgery |
Department of Visceral and Thoracic Surgery, Winterthur |
Kantonale Ethikkommission Zürich | 13.08.2021 | |||||||
| 2021-01188 | Effect of exercise and sport on anxiety in social situations | non clinical, involving persons | monocentric | A | Irma Heller | University of Lucerne |
University of Lucerne (PhD student), Lucerne |
Ethikkommission Nordwest- und Zentralschweiz EKNZ | 23.07.2021 | ||||||
| 2021-01187 | Randomized, double-blind, placebo-controlled crossover trial assessing the impact of the SGLT2 inhibitor empagliflozin on postprandial hypoglycaemia after gastric bypass | clinical trial | drugs | phase 3 | monocentric | B | Prof. Dr. med. et phil. Lia Bally | Department of Diabetes, Endocrinology, Nutritional Medicine and Metabolism, Inselspital, Bern University Hospital and University of Bern |
Department of Diabetes, Endocrinology, Nutritional Medicine and Metabolism, Inselspital, Bern University Hospital and University of Bern, Bern |
Kantonale Ethikkommission Bern | 23.09.2021 | Study has ended | |||
| 2021-01186 | Effect of a high intensity interval training (HIIT) rehabilitation program on exercise capacity in lung and kidney transplant recipients | clinical trial | other clinical trials | monocentric | A | Dr phil. Aurelien Bringard | Hôpitaux Universitaires de Genève |
Service de Pneumologie, Hôpitaux Universitaires de Genève, Genève |
Commission Cantonale d'éthique de la recherche Genève (CCER) | 08.12.2021 | |||||
| 2021-01185 |
APical puLmonary space-occupying lesions as incidental findings in CT- basEd acUte stRoke imAging – A retrospective single-center cohort study. The PLEURA Study. |
personal data/biological material | monocentric | PD Dr. med. Gian Marco De Marchis | University Hospital Basel |
University Hospital Basel, Basel |
Ethikkommission Nordwest- und Zentralschweiz EKNZ | 22.06.2021 | |||||||
| 2021-01184 | GBM AGILE Global Adaptive Trial Master Protocol: An International, Seamless Phase II/III Response Adaptive Randomization Platform Trial Designed To Evaluate Multiple Regimens In Newly Diagnosed and Re More ... | clinical trial | drugs | phase 2 | multicentric | C | Prof. Dr. Michael Weller | Global Coalition for Adaptive Research |
Universitätsspital Zürich, Klinik für Neurologie, Zürich Universitätsspital Basel, Basel CHUV, département d’oncologie, Lausanne |
Kantonale Ethikkommission Zürich | Ethikkommission Nordwest- und Zentralschweiz EKNZ, Commission cantonale d'Éthique de la Recherche sur l'être humain Vaud (CER-VD) | 07.12.2021 | |||
| 2021-01183 | „Validierte Sprachübertragung des Fragebogens Spinal Cord Injury-Spasticity Evaluation Tool in die deutsche Sprache“ | non clinical, involving persons | monocentric | A | Dr. med. Tim Reck | Schweizer Paraplegiker-Zentrum |
Schweizer Paraplegiker-Zentrum, Nottwil |
Ethikkommission Nordwest- und Zentralschweiz EKNZ | 05.07.2021 | ||||||
| 2021-01182 |
Post-operative outcomes of pain management in spinal fusion surgery (STX-101) |
non clinical, involving persons | monocentric | A | Prof. Dr. med. Lorin M. Benneker | SentryX B.V., the Netherlands |
Orthopädie Sonnenhof, 3006 Bern |
Kantonale Ethikkommission Bern | 01.11.2021 | ||||||
| 2021-01181 | Comparison between sacrocervicopexy (SCP) and sacro-spinous fixation (SSF) of the uterine cervix in the treatment of genital prolapse. A randomised controlled study. | clinical trial | other clinical trials | monocentric | A | Dr Chahin Achtari, PD, MER | CHUV - Gynécologie |
CHUV, Lausanne |
Commission cantonale d'Éthique de la Recherche sur l'être humain Vaud (CER-VD) | 07.12.2021 | |||||
| 2021-01180 | Sledding related trauma: a 10-year retrospective study of patients with injuries admitted to a single tertiary trauma center in Switzerland | personal data/biological material | monocentric | Prof. Aristomenis Exadaktylos | UNZ Inselspital Bern |
UNZ Inselspital Bern, Bern |
Kantonale Ethikkommission Bern | 13.07.2022 | |||||||