| BASEC ID | Project title | Type of project | Type of clinical trial | Study phase (clinical trials only) | multi- / monocentric | Category | Principal investigator | Sponsor | Investigational sites | Lead EC | Local EC(s) | Approval date | Minors | Study Ended | |
|---|---|---|---|---|---|---|---|---|---|---|---|---|---|---|---|
| 2023-00108 | Evaluation of an RNA-based assay for subtyping breast cancer and characterizing its proliferativ potential | personal data/biological material | monocentric | PD Dr Marcus Vetter | Kantonsspital Baselland, Liestal |
Kantonsspital Baselland, Liestal, Liestal |
Ethikkommission Nordwest- und Zentralschweiz EKNZ | 20.04.2023 | |||||||
| 2023-00107 | E/I balance in schizophrenia and autism spectrum disorder | non clinical, involving persons | monocentric | A | Prof. Dr. Philipp Sterzer | University Psychiatric Clinics (UPK) Basel |
University Psychiatric Clinics (UPK) Basel, Basel |
Ethikkommission Nordwest- und Zentralschweiz EKNZ | 08.03.2023 | ||||||
| 2023-00106 | Structural neuroplasticity promoted by psilocybin-assisted group psychotherapy in alcohol use disorder: a prospective cohort study | non clinical, involving persons | monocentric | A | Prof. Dr. phil. Leila M. Soravia | Universitätsklinik für Psychiatrie und Psychotherapie |
Universitätsklinik für Psychiatrie und Psychotherapie, Bern |
Kantonale Ethikkommission Bern | 15.05.2023 | ||||||
| 2023-00105 | Hemodynamic phenotype-based, capillary refill time-targeted resuscitation in early septic shock: The ANDROMEDA-SHOCK-2 Randomized Clinical Trial study protocol | clinical trial | other clinical trials | monocentric | A | Prof. Dr. Sascha David | Erasmus University Medical Center Rotterdam |
University Hospital Zurich, Zurich |
Kantonale Ethikkommission Zürich | 16.05.2023 | |||||
| 2023-00104 | Role of soluble Tie2 in septic shock patients | personal data/biological material | monocentric | Prof. Dr. med. Sascha David |
Institut für Intensivmedizin USZ, Zürich |
Kantonale Ethikkommission Zürich | 28.02.2023 | ||||||||
| 2023-00103 | A Multi-Center, Retrospective Review of Implant-Based Post Mastectomy Breast Reconstruction Utilizing SurgiMend® Collagen Matrix in Prepectoral and Submuscular Surgical Approaches | personal data/biological material | monocentric | Prof. Dr. med. Yves Harder | Integra LifeSciences (United States) |
Ospedale Regionale di Lugano, Lugano |
Comitato etico cantonale Ticino | 16.03.2023 | Study has ended | ||||||
| 2023-00102 | BN42489: A PHASE II, RANDOMIZED, DOUBLE-BLIND, PLACEBO-CONTROLLED, DOSE-FINDING STUDY TO EVALUATE THE SAFETY, BIOMARKERS, AND EFFICACY OF TOMINERSEN IN INDIVIDUALS WITH PRODROMAL AND EARLY MANIFEST HU More ... | clinical trial | drugs | phase 2 | multicentric | C | Prof. em. Dr. med. Jean-Marc Burgunder | Roche Pharma (Schweiz) AG |
NeuroZentrum Siloah AG, Gümligen Neurologie und Neurologische Poliklinik, Universitätsspital Basel, Petersgraben 4, 4031 Basel |
Kantonale Ethikkommission Bern | Ethikkommission Nordwest- und Zentralschweiz EKNZ | 01.05.2023 | |||
| 2023-00101 | Severe Paediatric Asthma Collaborative in Europe | non clinical, involving persons | monocentric | A | Prof. Dr. Alexander Möller | Queen Mary University of London |
Universitäts-Kinderspital Zürich, Zürich |
Kantonale Ethikkommission Zürich | 21.04.2023 | yes | |||||
| 2023-00100 | Effect of anastomosis time on outcome after pancreas transplantation – a multicenter analysis | personal data/biological material | monocentric | Dr. med. Fabian Rössler | Universitätsspital Zürich - Department of Surgery and Transplantation |
Universitätsspital Zürich, Zürich |
Kantonale Ethikkommission Zürich | 28.03.2023 | |||||||
| 2023-00099 | Phase I clinical trial testing the dose escalation and expansion of Pressurized IntraThoracic Hyperthermic Aerosol Cisplatin administration (PITHAC) for the management of pleural carcinosis | clinical trial | drugs | phase 1/2 | monocentric | B | Dr Jean Yannis PERENTES | CHUV |
CHUV, Lausanne |
Commission cantonale d'Éthique de la Recherche sur l'être humain Vaud (CER-VD) | 17.07.2023 | ||||
| 2023-00098 | Computer-navigated, stereotactic, percutaneous radiofrequency ablation of osteoid osteomas: dose comparison and procedure times | personal data/biological material | monocentric | Dr. med. Frank Mosler | Inselspital |
Inselspital, Bern |
Kantonale Ethikkommission Bern | 16.03.2023 | |||||||
| 2023-00097 | SwissLEGIO-CAP: a multicentre case-control study on clinical, laboratory and radiological characteristics of community-acquired Legionnaires’ disease | personal data/biological material | multicentric | Prof Daniel Mäusezahl | Swiss Tropical and Public Health Institute |
Swiss Tropical and Public Health Institute, Allschwil Universitätsspital Basel, 4031 Basel Kantonsspital St. Gallen, 9007 St. Gallen |
Ethikkommission Nordwest- und Zentralschweiz EKNZ | Ethikkommission Nordwest- und Zentralschweiz EKNZ, Ethikkommission Ostschweiz (EKOS) | 08.03.2023 | ||||||
| 2023-00096 | Immediate versus delayed loading of single posterior zirconia implants: A multicenter randomized controlled clinical trial | clinical trial | other clinical trials | multicentric | A | PD Dr. Goran Benic | Università degli Studi di Milano |
Medici Dentisti Manno Lugano, Manno Medici Dentisti Manno Lugano, Manno Studio Dr. Kraus, Lugano |
Comitato etico cantonale Ticino | Comitato etico cantonale Ticino | 24.05.2023 | ||||
| 2023-00095 | General Skin and Nasal Decolonization with octenisan® Set be-fore and after Elective Orthopedic Surgery in Selected Patients at Elevated Risk for Revision Surgery and Surgical Site Infections | clinical trial | drugs | n/a | monocentric | A | Prof. Dr. med. Ilker Uçkay | UNIVERSITÄTSKLINIK BALGRIST |
Universitätsklinik Balgrist, Züerich |
Kantonale Ethikkommission Zürich | 24.02.2023 | ||||
| 2023-00094 | Characterization of patients with acute myocardial infarction and treatment using mechanical cardiovascular support systems | personal data/biological material | monocentric | Prof. Dr. Barbara Stähli | Universitätsspital Zürich |
Universitätsspital Zürich, Zürich |
Kantonale Ethikkommission Zürich | 12.05.2023 | |||||||
| 2023-00093 | Hands-on approach towards quantifiable and scientific useful data anonymization for large medical datasets | personal data/biological material | monocentric | Dr Patrick Stähli | IDSC, Insel Data Science Center |
IDSC, Bern |
Kantonale Ethikkommission Bern | 15.03.2023 | |||||||
| 2023-00092 | Patient-specific fully-automatic finite element modelling for the prediction of screw loos-ening following dorsal instrumentation of the lumbar spine | personal data/biological material | monocentric | Prof. Dr. med. Mazda Farshad | Universitätsklinik Balgrist |
Universitätsklinik Balgrist, Zürich |
Kantonale Ethikkommission Zürich | 24.02.2023 | |||||||
| 2023-00090 | Optimization of mesenteric vascular mapping by dual-energy computed tomography using a split-bolus injection of contrast medium | personal data/biological material | monocentric | Dr med Lucien Widmer |
HFR Fribourg - Hôpital cantonal, 1700 Fribourg |
Commission cantonale d'Éthique de la Recherche sur l'être humain Vaud (CER-VD) | 02.02.2023 | ||||||||
| 2023-00089 | Retrospektive Analyse von Azistespunktaten zur Identifikation potenzieller diskrimierender Faktoren für verschiedene Krankheitsentitäten. | personal data/biological material | monocentric | Prof. Dr. Dr. Andreas Wicki | Unviersitätsspital Zürich |
Universitätsspital Zürich, Zurich |
Kantonale Ethikkommission Zürich | 18.04.2023 | |||||||
| 2023-00088 | Understanding patient altruism at the end of life: An interdisciplinary approach | non clinical, involving persons | multicentric | A | Prof Mathieu Bernard | Palliative and Supportive Care Service, Lausanne University Hospital and University of Lausanne |
Palliative and Supportive Care Service, Lausanne University Hospital, Lausanne Bern University Hospital, Bern Ospedale Regionale di Bellinzona e Valli - Bellinzona, Bellinzona Zürich University Hospit More ... |
Commission cantonale d'Éthique de la Recherche sur l'être humain Vaud (CER-VD) | Kantonale Ethikkommission Bern, Kantonale Ethikkommission Zürich, Comitato etico cantonale Ticino | 25.07.2023 | |||||