BASEC ID Project title Type of project Type of clinical trial Study phase (clinical trials only) multi- / monocentric Category Principal investigator Sponsor Investigational sites Lead EC Local EC(s) Approval date Minors Study Ended
2023-00198 Deciphering the mechanisms regulating human blood cell population size control non clinical, involving persons monocentric A Prof. Dr. Jean Pieters Biozentrum, Universität Basel Biozentrum, Umiversität Basel, Basel
Ethikkommission Nordwest- und Zentralschweiz EKNZ 31.03.2023
2023-00197 Outcomes of late compared to early truncus arteriosus surgical correction. personal data/biological material monocentric Dr Julie Wacker Hôpitaux Universitaires de Genève, Genève
Commission Cantonale d'éthique de la recherche Genève (CCER) 17.04.2023
2023-00196 Evaluation of age estimation tools for cancerous disease-affected individuals non clinical, involving persons monocentric A PD Dr. sc. nat. Cordula Haas University of Zurich University of Zurich, Zurich
Kantonale Ethikkommission Zürich 18.04.2023
2023-00195 A Randomized Phase 3 Study of Datopotamab Deruxtecan (Dato-DXd) and Pembrolizumab, with or Without Platinum Chemotherapy, in Subjects with No Prior Therapy for Advanced or Metastatic PD-L1 TPS <50% No More ... clinical trial drugs phase 3 multicentric C Dr. Pirmin Häuptle Daiichi Sankyo, Inc. Kantonsspital Baselland, Liestal
Spital STS AG Thun, Thun
Kantonspital St. Gallen, St. Gallen
Ethikkommission Nordwest- und Zentralschweiz EKNZ Ethikkommission Ostschweiz (EKOS), Kantonale Ethikkommission Bern 25.05.2023
2023-00193 Outcomes after transjugular intrahepatic portosystemic shunt (TIPS) in a Swiss cohort personal data/biological material monocentric Prof. Annalisa Berzigotti UVCM Hepatology UVCM Hepatology, 3010 Bern
Kantonale Ethikkommission Bern 30.03.2023
2023-00191 Temporal lobectomy series – Survival of patients with glioblastoma treated with temporal lobectomy compared to a historical cohort of patients treated with gross total resection personal data/biological material monocentric Dr. med. Jenny Kienzler Klinik für Neurochirurgie, Aarau
Ethikkommission Nordwest- und Zentralschweiz EKNZ 14.02.2023
2023-00189 Charakterisierung von HER2 low an primären Mammakarzinomen:
Bestimmung HER-2 Status anhand von mRNA im Vergleich zu Immunhistochemie und FISH Analyse
personal data/biological material monocentric Dr. med. Paula Klersy Kantonsspital St. Gallen Kantonsspital, St. Gallen
Ethikkommission Ostschweiz (EKOS) 09.02.2023
2023-00188 Seizure, cognitive, and functional outcomes of pediatric epilepsy surgery personal data/biological material monocentric Prof. Dr. med. Georgia Ramantani Universitäts-Kinderspital Zürich Universitäts-Kinderspital, Zürich
Kantonale Ethikkommission Zürich 04.04.2023
2023-00187 CA099-003:A Phase 1/2 Study of BMS-986408 Alone and in Combination with Nivolumab or with
Nivolumab and Ipilimumab in Participants with Advanced Solid Tumors
clinical trial drugs phase 1/2 multicentric C Prof. Dr. med. Markus Jörger Bristol-Myers Squibb International Corporation Kantonsspital St. Gallen, St. Gallen
University Hospital Basel, Medical Oncology, Basel
University Hospital Geneva, Geneva
Ethikkommission Ostschweiz (EKOS) Ethikkommission Nordwest- und Zentralschweiz EKNZ, Commission Cantonale d'éthique de la recherche Genève (CCER) 10.05.2023
2023-00186 Functional profiling of CD4 T cells in human cancer for optimized cancer immunotherapy personal data/biological material monocentric Camilla Jandus University of Geneva, 1211 Geneva
Commission Cantonale d'éthique de la recherche Genève (CCER) 03.04.2023
2023-00185 Life of lesions in ANCA-associated glomerulonephritis personal data/biological material monocentric PD Dr Helmut Hopfer Universitätsspital Basel Universitätsspital Basel, Basel
Ethikkommission Nordwest- und Zentralschweiz EKNZ 03.04.2023
2023-00184 Analysis of sexual health of patients with low grade glioma treated with pencil beam scanning proton therapy non clinical, involving persons monocentric A Prof.Dr.med. Damien C. Weber Center for Protontherapy at Paul Scherrer Institut Center for Protontherapy at Paul Scherrer Institut, Villigen
Ethikkommission Nordwest- und Zentralschweiz EKNZ 21.03.2023
2023-00182 Comparison of two perioperative analgesia strategies: epidural catheters vs. intravenous methadone personal data/biological material monocentric Prof. Dr. med. Donat R. Spahn Institut für Anästhesiologie Institut für Anästhesiologie - USZ, Zürich
Kantonale Ethikkommission Zürich 17.03.2023
2023-00180 Fat fractions of the rotator cuff muscles acquired with two-point Dixon MR imaging predicting outcome after arthroscopic rotator cuff repair personal data/biological material monocentric Prof. Dr. med. Reto Sutter University Hospital Balgrist University Hospital Balgrist, Zürich
Kantonale Ethikkommission Zürich 07.03.2023
2023-00179 Neural correlates of willful ignorance decisions – an observational fMRI study non clinical, involving persons monocentric A Dr Thomas Baumgartner University of Bern University of Bern, Bern
Kantonale Ethikkommission Bern 05.05.2023
2023-00176 The impact of exercise on cognitive performance and subjective feeling of fatigue non clinical, involving persons monocentric A Prof Nicolas Place ISSUL Université de Lausanne, Lausanne
Commission cantonale d'Éthique de la Recherche sur l'être humain Vaud (CER-VD) 09.05.2023
2023-00175 Evaluation of Safety and Tolerability of Salvia haenkei extract as a Dietary Supplement Ingredient in a Healthy Population: A Randomized, Open label, Parallel-arm, Two-dose Study clinical trial other clinical trials monocentric B Dr. Roberta Noseda IBSA Farmaceutici Italia Srl Istituto di Scienze Farmacologiche della Svizzera Italiana, Lugano
Comitato etico cantonale Ticino 13.04.2023
2023-00174 A Phase 1/2 open-label study of Debio 0123 in combination with temozolomide
in adult participants with recurrent or progressive glioblastoma and of
Debio 0123 in combination with temozolomide and r More ...
clinical trial drugs phase 1/2 monocentric C Prof. Dr. med. Patrick Roth Debiopharm International S.A. Department of Neurology, University Hospital Zürich, Zürich
Kantonale Ethikkommission Zürich 28.03.2023
2023-00173 IMPACT: Increasing mental health and psychological well-being in patients and healthy adults through nonexercise activity clinical trial other clinical trials monocentric A Prof. Dr. Claudio R. Nigg Universität Bern Institut für Sportwissenschaft, Universität Bern, Bern
Kantonale Ethikkommission Bern 21.04.2023
2023-00171 ONC201 for the Treatment of Newly Diagnosed H3 K27M-mutant Diffuse Glioma Following Completion of Radiotherapy: A Randomized, Double-Blind, Placebo-Controlled, Multicenter Study clinical trial drugs phase 3 multicentric C Dr Emilie Le Rhun Chimerix, Inc. University Hospital Zurich, Zurich
Lausanne University Hospital Center (CHUV), Lausanne
Kantonale Ethikkommission Zürich Commission cantonale d'Éthique de la Recherche sur l'être humain Vaud (CER-VD) 02.06.2023