| BASEC ID | Project title | Type of project | Type of clinical trial | Study phase (clinical trials only) | multi- / monocentric | Category | Principal investigator | Sponsor | Investigational sites | Lead EC | Local EC(s) | Approval date | Minors | Study Ended | |
|---|---|---|---|---|---|---|---|---|---|---|---|---|---|---|---|
| 2024-01795 | Federated Analysis/Federated learning Architecture in Imaging - Proof of Concept Study | personal data/biological material | monocentric | Prof. Cristina Granziera |
Research Center for Clinical Neuroimmunology and Neuroscience Basel (RC2NB), Basel |
Ethikkommission Nordwest- und Zentralschweiz EKNZ | 25.09.2024 | ||||||||
| 2024-01794 | CARE-INSIGHTS: Cancer and Realistic Expectations - Insights into Prognostic understanding, Preferences, Inequalities, Needs, Support, and Empowerment for Patients and Family Members Study | non clinical, involving persons | multicentric | A | Dr. Christoph Becker | University Hospital Basel |
University Hospital Basel, Basel St. Claraspital, Basel Kantonsspital Baden, Baden Kantonsspital Baselland Liestal, Liestal |
Ethikkommission Nordwest- und Zentralschweiz EKNZ | Ethikkommission Nordwest- und Zentralschweiz EKNZ | 26.11.2024 | |||||
| 2024-01793 | Effect of feeding jejunostomy placement on sarcopenia in patients with advanced stages of esophageal cancer in curate cancer treatment | personal data/biological material | monocentric | Dr. med. Stefan Gutknecht | Stadtspital Zürich Triemli |
Stadtspital Zürich Triemli, Zürich |
Kantonale Ethikkommission Zürich | 19.11.2024 | |||||||
| 2024-01791 | Clinical outcomes of kidney transplant in obese recipients: a retrospective study | personal data/biological material | monocentric | PD Dr David Martin | CHUV - Chirurgie viscérale |
CHUV, Lausanne |
Commission cantonale d'Éthique de la Recherche sur l'être humain Vaud (CER-VD) | 10.10.2024 | |||||||
| 2024-01788 |
M24-885: A Phase 2a Multicenter, Randomized, Platform Study of Targeted Therapies for the Treatment of Adult Subjects with Moderate to Severe Crohn's Disease |
clinical trial | drugs | phase 2 | monocentric | C | Dr. Pascal Juillerat | AbbVie Inc. |
Intesto - Gastroenterologische Praxis & Crohn-Colitis Zentrum, Bern |
Kantonale Ethikkommission Bern | 17.12.2024 | ||||
| 2024-01787 | Learning curves in robotic liver surgery | personal data/biological material | monocentric | PD Dr. med. Philip Müller | Clarunis, University Hospital Basel |
Clarunis, University Hospital Basel, Basel |
Ethikkommission Nordwest- und Zentralschweiz EKNZ | 06.09.2024 | |||||||
| 2024-01784 | Cone beam computed tomography (CBCT) image calibration and dental implant stability assessment | deceased persons | monocentric | Patrik Wili | Universität Bern |
ARTORG Centre, Universität Bern, Bern |
Kantonale Ethikkommission Bern | 05.11.2024 | |||||||
| 2024-01781 | Utilisation des techniques d’anesthésie locorégional dans un service héliporté médicalisé d’urgence alpin | personal data/biological material | monocentric | Dr. med. Alexandre Moser | Air Glaciers SA |
Air Glaciers SA, Sion |
Commission cantonale d'Éthique de la Recherche sur l'être humain Vaud (CER-VD) | 12.11.2024 | |||||||
| 2024-01779 | Vorkommen von Sehstörungen bei Kindern in der Kinder-Reha Schweiz - Eine retrospektive Analyse. | personal data/biological material | monocentric | Prof. Dr. med. Christina Gerth-Kahlert |
UniversitätsSpital Zürich, Zürich |
Kantonale Ethikkommission Zürich | 31.10.2024 | ||||||||
| 2024-01778 | Age-associated NAD decline impairs mitochondrial metabolism and function of CAR-T cells | personal data/biological material | monocentric | Pr Denis Migliorini | University of Geneva |
UNIGE, Geneva |
Commission Cantonale d'éthique de la recherche Genève (CCER) | 28.10.2024 | |||||||
| 2024-01776 | UVASC - Urethral vascularization and urodynamics | non clinical, involving persons | monocentric | A | Dr. Med. Diana Höhn |
Universitätsfrauenklinik, Inselspital, Bern |
Kantonale Ethikkommission Bern | 06.01.2025 | |||||||
| 2024-01774 | Sensory Perception Abnormalities in Children with developmental delays: Observations and Testing (SPOT) | non clinical, involving persons | monocentric | A | PD Dr. med. Michael von Rhein | Universitäts-Kinderspital Zürich |
University Childrens Hospital Zürich, Zürich |
Kantonale Ethikkommission Zürich | 06.12.2024 | yes | |||||
| 2024-01773 | Early Detection of Lung Cancer by analyzing Volatile Organic Compounds in Human Breath | non clinical, involving persons | monocentric | A | Prof. Dr. med. Othmar Schöb | Klinik Hirslanden Zürich |
Klinik Hirslanden, Zürich |
Kantonale Ethikkommission Zürich | 10.01.2025 | ||||||
| 2024-01768 | A Phase II, Open-label Study to Evaluate the Safety, Tolerability, Pharmacokinetics, Immunogenicity, and Antitumor Activity of Volrustomig Priming Regimens in Combination with other Anticancer Agents More ... | clinical trial | drugs | phase 2 | multicentric | C | Dr. med. Laetitia Mauti | AstraZeneca AB |
Kantonsspital Winterthur, Winterthur Hôpitaux Universitaires de Genève, Genève CHUV, Centre hospitalier universitaire vaudois, Lausanne UniversitätsSpital Zürich, Zürich |
Kantonale Ethikkommission Zürich | Kantonale Ethikkommission Zürich, Commission cantonale d'Éthique de la Recherche sur l'être humain Vaud (CER-VD), Commission Cantonale d'éthique de la recherche Genève (CCER) | 17.12.2024 | |||
| 2024-01767 |
The Swiss Integrated Care (INCA) Study: Establishing a Cohort Study of Patients in Supported Family Care |
non clinical, involving persons | monocentric | A | Prof. Dr. Viktor von Wyl | University of Zurich |
University of Zurich, Zurich |
Kantonale Ethikkommission Zürich | 10.01.2025 | ||||||
| 2024-01765 | A Phase 3, Randomized, Open-Label, Active-Controlled Study to Evaluate a Switch to an Oral Weekly Islatravir/Lenacapavir Regimen in People With HIV‑1 Who Are Virologically Suppressed on Standard of Ca More ... | clinical trial | drugs | phase 3 | multicentric | C | Prof. Dr. med. Matthias Cavassini | Gilead Sciences, Inc. |
CHUV, Lausanne Inselspital, Bern HUG, Genève |
Commission cantonale d'Éthique de la Recherche sur l'être humain Vaud (CER-VD) | Kantonale Ethikkommission Bern, Commission Cantonale d'éthique de la recherche Genève (CCER) | 23.12.2024 | |||
| 2024-01764 | Utilization of Volatile Organic Compounds for Monitoring Treatment Responses, Detection of Postoperative Complications and Tumor Follow Up in Esophageal Cancer | non clinical, involving persons | monocentric | A | Dr. med. Dr. sc. nat. Marcel Schneider | UniversitätsSpital Zürich |
Department of Visceral- and Transplant Surgery, University Hospital Zurich, Zurich |
Kantonale Ethikkommission Zürich | 10.01.2025 | ||||||
| 2024-01763 | A Phase 3, Randomized, Double-Blind, Active-Controlled Study to Evaluate a Switch to an Oral Weekly Islatravir/Lenacapavir Regimen in People With HIV-1 Who Are Virologically Suppressed on Bictegravir/ More ... | clinical trial | drugs | phase 3 | multicentric | C | Prof. Dr. med. Matthias Cavassini | Gilead Sciences, Inc. |
CHUV, Lausanne Inselspital, Bern USZ, Zürich |
Commission cantonale d'Éthique de la Recherche sur l'être humain Vaud (CER-VD) | Kantonale Ethikkommission Bern, Kantonale Ethikkommission Zürich | 23.12.2024 | |||
| 2024-01761 | MK-1022-011: A Phase 1/2 Study to Evaluate the Safety and Efficacy of Patritumab Deruxtecan in Gastrointestinal Cancers | clinical trial | drugs | phase 1/2 | multicentric | C | Dr. med. Thibaud Kössler | Merck Sharp & Dohme LLC |
Hôpitaux Universitaires Genève (HUG), Genève UniversitätsSpital Zürich, Zürich |
Commission Cantonale d'éthique de la recherche Genève (CCER) | Kantonale Ethikkommission Zürich | 07.11.2024 | |||
| 2024-01760 | Epidemiologische Analyse von Krankheiten und Risikofaktoren anhand von Autopsien. | personal data/biological material | monocentric | Dr. Umberto Maccio | Universitätsspital Zürich |
Universitätsspital Zürich, Institut für Pathologie und Molekularpathologie, Zürich |
Kantonale Ethikkommission Zürich | 17.12.2024 | |||||||