BASEC ID Project title Type of project Type of clinical trial Study phase (clinical trials only) multi- / monocentric Category Principal investigator Sponsor Investigational sites Lead EC Local EC(s) Approval date Minors Study Ended
2022-02136 M23-696: A Phase 3b/4 Randomized, Open-label, Efficacy Assessor Blinded Study, Comparing the Safety and Assessor Blinded Efficacy of Upadacitinib to Dupilumab in Subjects with Moderate to Severe Atopi More ... clinical trial drugs phase 3 multicentric C Dr. Ieva Saulite AbbVie Inc. Kantonsspital St. Gallen, St. Gallen
Inselspital, Universitätsklinik für Dermatologie, Bern
Universitätsspital Basel, Dermatologie, Basel
Universitätsspital Zürich, Dermatologische Klinik, Zürich
Ethikkommission Ostschweiz (EKOS) Ethikkommission Nordwest- und Zentralschweiz EKNZ, Kantonale Ethikkommission Bern, Kantonale Ethikkommission Zürich 09.03.2023 yes
2022-02134 Risk factors for the use of a primary higher-constrained total knee arthroplasty
– a retrospective single-center analysis
personal data/biological material monocentric Prof. Dr. med. Sandro Fucentese Universitätsklinik Balgrist Universitätsklinik Balgrist, Zürich
Kantonale Ethikkommission Zürich 22.12.2022
2022-02131 A multicenter, international, randomized, active comparator-controlled, double-blind, doubledummy, parallel-group, 2-arm, Phase 3 study to compare the efficacy and safety of the oral FXIa inhibitor as More ... clinical trial drugs phase 3 multicentric C Prof. Dr. med. Angelo Auricchio Bayer AG Istituto Cardiocentro Ticino, Lugano
lnselspital Bern, Bern
Universitätsspital Basel, Basel
Kantonspital Aarau AG, Aarau
Kantonsspital Baden AG, Baden
Kantonsspital St. Gallen, St. Gallen
Universitäts More ...
Comitato etico cantonale Ticino Ethikkommission Nordwest- und Zentralschweiz EKNZ, Ethikkommission Ostschweiz (EKOS), Kantonale Ethikkommission Bern, Kantonale Ethikkommission Zürich 13.02.2023
2022-02130 CAIN457C22301 - A randomized, parallel-group, double-blind, placebo-controlled, multicenter Phase III trial to evaluate efficacy and safety of secukinumab administered subcutaneously versus placebo, i More ... clinical trial drugs phase 3 multicentric C Prof. Dr. med. Andrea Rubbert-Roth Novartis Pharma Schweiz AG Kantonsspital St. Gallen, St. Gallen
Universitätsspital, Basel
HFR Fribourg – Hôpital Cantonal, Fribourg
Ethikkommission Ostschweiz (EKOS) Ethikkommission Nordwest- und Zentralschweiz EKNZ, Commission cantonale d'Éthique de la Recherche sur l'être humain Vaud (CER-VD) 16.02.2023
2022-02129 A two-part, randomized, placebo controlled, double blind, multicenter, Phase 3 study to evaluate the efficacy and safety of linerixibat for the treatment of cholestatic pruritus in participants with p More ... clinical trial drugs phase 3 monocentric C PD Dr. med. Benedetta Terziroli Beretta-Piccoli GlaxoSmithKline Research & Development Limited Epatocentro Ticino, Lugano
Comitato etico cantonale Ticino 27.02.2023
2022-02127 An exploratory study on autoantibodies in cancer patients – IOSI-IRB-001 study personal data/biological material monocentric Dr. med. Ilaria Colombo Istituto Oncologico della Svizzera Italiana Istituto Oncologico della Svizzera Italiana, Bellinzona
Comitato etico cantonale Ticino 25.01.2023
2022-02124 Sleep disordered breathing in children and adolescents with obesity non clinical, involving persons monocentric A Dre Virginie Bayon CHUV - CIRS - BH 06 CHUV, Lausanne
Commission cantonale d'Éthique de la Recherche sur l'être humain Vaud (CER-VD) 26.01.2023 yes
2022-02123 Cancer du sein et CAFs (cancer associated fibroblasts) : identification de marqueurs de surface prédictifs de la réponse à la chimiothérapie néoadjuvante personal data/biological material monocentric Dr Loïc Lelièvre Fondation pour le perfectionnement et la recherche en gynécologie et obstétrique CHUV/UNIL, Lausanne
Commission cantonale d'Éthique de la Recherche sur l'être humain Vaud (CER-VD) 23.03.2023
2022-02121 Bleeding of unknown cause, insight into a multifactorial bleeding disorder: a Swiss case-control study non clinical, involving persons multicentric A Dr Alessandro Casini University Hospitals of Geneva, Geneva
Ente Ospedaliero Cantonale, Bellinzona
Clinica Luganese Moncucco, Lugano
Commission Cantonale d'éthique de la recherche Genève (CCER) Comitato etico cantonale Ticino 01.02.2023
2022-02119 Mechanisms of type 1 diabetes endophenotypes, by cluster analysis non clinical, involving persons monocentric A Prof. Valérie Schwitzgebel Hôpitaux Universitaire de Genève HUG, Geneva
Commission Cantonale d'éthique de la recherche Genève (CCER) 17.01.2023 yes
2022-02118 Optimized post mortem, multi-scale imaging and transcriptomic analysis of the human thalamus and cortex deceased persons monocentric Prof. Andras Jakab University of Zürich University Children's Hospital Zürich / University of Zürich, Zürich
Kantonale Ethikkommission Zürich 27.01.2023
2022-02116 Introduction of a documentation protocol for Rezum water therapy of the prostate and analysis of practice patterns via retrospective application in a multiuser high-volume center. personal data/biological material monocentric Prof. Dr. Christian Wetterauer University Hospital Basel University Hospital Basel, Basel
Ethikkommission Nordwest- und Zentralschweiz EKNZ 04.01.2023
2022-02114 Measured values of clotting times and coagulation factors in patients treated with asparaginase for acute lymphoblastic leukemia personal data/biological material monocentric Dr Vasiliki Papadopoulou CHUV - Oncologie CHUV, Lausanne
Commission cantonale d'Éthique de la Recherche sur l'être humain Vaud (CER-VD) 12.12.2022
2022-02113 LOST DIAGNOSES? EINE UNTERSUCHUNG ZU ADHS-DIAGNOSEN BEI PERSONEN MIT EINER STRAFRECHTLICH ANGEORDNETEN THERAPEUTISCHEN MASSNAHME. personal data/biological material monocentric Prof. Dr. med. Michael Liebrenz Forensisch-Psychiatrischer Dienst, Universität Bern Forensisch-Psychiatrischer Dienst, Universität Bern, Bern
Kantonale Ethikkommission Bern 24.02.2023
2022-02111 Epidemiology of invasive Candida infections in solid organ transplant recipients over time and risk factor analysis based on the Swiss Transplant Cohort Study. personal data/biological material multicentric Dr Dionysios Neofytos Hôpitaux Universitaires de Genève Hôpitaux universitaires de Genève, Geneva
Insel Spital Bern, Bern
Unispital Basel, Basel
Cantonal Hospital St.Gallen, St Gallen
Centre hospitalier universitaire vaudois, Lausanne
Universitätsspital Zü More ...
Commission Cantonale d'éthique de la recherche Genève (CCER) Ethikkommission Nordwest- und Zentralschweiz EKNZ, Ethikkommission Ostschweiz (EKOS), Kantonale Ethikkommission Bern, Kantonale Ethikkommission Zürich, Commission cantonale d'Éthique de la Recherche s More ... 06.12.2022
2022-02110 Fuite biliaire après hépatectomie : incidence, facteurs de risque et prise en charge. personal data/biological material monocentric Dr Gaëtan-Romain Joliat CHUV - Chirurgie viscérale Centre hospitalier universitaire vaudois, Lausanne
Commission cantonale d'Éthique de la Recherche sur l'être humain Vaud (CER-VD) 13.12.2022
2022-02108 Influences in intracranial aneurysms – multicentre approach to develop a registry and biomedical resource in patients affected by intracranial aneurysms non clinical, involving persons monocentric A PD Dr. med. Isabel Charlotte Hostettler Canton Hospital St. Gallen Canton Hospital St. Gallen, St. Gallen
Ethikkommission Ostschweiz (EKOS) 26.01.2023
2022-02107 Swiss Hereditary Angioedema (HAE) Cohort study non clinical, involving persons multicentric A PD Dr. med. Urs Steiner Inselspital Bern Inselspital Bern, Department of Rheumatology and Immunology, Bern
Allergologie/Klinische Immunologie, Bern
Kantonsspital Luzern, Luzern
Kantonsspital St. Gallen, St. Gallen
Ostschweizer Kinderspital, More ...
Kantonale Ethikkommission Bern Ethikkommission Nordwest- und Zentralschweiz EKNZ, Ethikkommission Ostschweiz (EKOS), Kantonale Ethikkommission Bern, Kantonale Ethikkommission Zürich 20.02.2023 yes
2022-02102 Activité et aptitude physique de la population âgée de la Fondation de Vernand : comparaison entre les usagers journaliers et les résidents internes non clinical, involving persons monocentric A PhD Davide Malatesta ISSUL-UNIL - Sciences du Sport Université de Lausanne, Lausanne
Commission cantonale d'Éthique de la Recherche sur l'être humain Vaud (CER-VD) 03.02.2023
2022-02100 Distribution of short-term heart rate variability patterns in long covid patients personal data/biological material monocentric Cyril Besson CHUV - Médecine du sport CHUV, Lausanne
Commission cantonale d'Éthique de la Recherche sur l'être humain Vaud (CER-VD) 02.02.2023