| BASEC ID | Project title | Type of project | Type of clinical trial | Study phase (clinical trials only) | multi- / monocentric | Category | Principal investigator | Sponsor | Investigational sites | Lead EC | Local EC(s) | Approval date | Minors | Study Ended | |
|---|---|---|---|---|---|---|---|---|---|---|---|---|---|---|---|
| 2024-D0045 | Overnight treatment of subacute stroke patients with insomnia using vestibular stimulation from a rocking bed (Somnomat Casa) – A feasibility study | clinical trial | medical devices | monocentric | C2 | Prof. Dr. med. Karsten Krakow | Sensory-Motor Systems Lab, IRIS, ETH Zurich |
Rehaklinik Zihlschlacht AG, 8588 Zihlschlacht |
Ethikkommission Ostschweiz (EKOS) | 27.06.2024 | |||||
| 2024-D0044 | Evaluation of correlations between volatile organic compounds (VOCs) spectra measured with GC-IMS and MOx-sensors and venous blood glucose in subjects with Type 2 Diabetes | clinical trial | in vitro diagnostic medical devices IVD-MD | monocentric | A2 | Prof. Dr. med. Markus Laimer | BOYDSense SAS |
Universitätsklinik für Diabetologie, Endokrinologie, Ernährungsmedizin & Metabolismus (UDEM) Inselspital, Bern |
Kantonale Ethikkommission Bern | 21.08.2024 | |||||
| 2024-D0043 | Single-center evaluation of Sleepiz One+ algorithms in estimating respiration rate and heart rate compared to gold standard | clinical trial | medical devices | monocentric | A1 | Dr. med. Christian Neumann | Sleepiz AG |
Zentrum für Schlafmedizin ‘Schlaflabor Fluntern’, Zurich |
Kantonale Ethikkommission Zürich | 16.07.2024 | |||||
| 2024-D0042 | LUNAR-2: Pivotal, Randomized, Open-Label Study of Tumor Treating Fields (TTFields, 150 kHz) Concomitant with Pembrolizumab and Platinum Based Chemotherapy for the Treatment of Metastatic Non-Small Cel More ... | clinical trial | medical devices | multicentric | C1 | Prof. Dr. med. Alessandra Curioni-Fontecedro | Novocure GmbH |
HFR Freiburg-Kantonsspital, Fribourg Kantonsspital Baden, Zentrum Onkologie/ Hämatologie, Im Ergel 1 |
Commission cantonale d'Éthique de la Recherche sur l'être humain Vaud (CER-VD) | Ethikkommission Nordwest- und Zentralschweiz EKNZ | 23.01.2025 | ||||
| 2024-D0041 | Artificial Intelligence assisted tracheal video intubation: an observational trial about correctness of Larynguide | clinical trial | medical devices | monocentric | A1 | Prof. Dr. med. Thomas Riva | aiEndoscopic AG |
Inselspital - Universitätsspital Bern, Bern |
Kantonale Ethikkommission Bern | 30.05.2024 | |||||
| 2024-D0040 | TicIn for the Treatment of coronAry lesioNs – PlAque Regression AnD stabilIsation with Sirolimus Elution Pilot Study | clinical trial | medical devices | monocentric | A2 | Prof. Marco Valgimigli | Istituto Cardiocentro Ticino, EOC |
Istituto Cardiocentro Ticino, Lugano |
Comitato etico cantonale Ticino | 09.01.2025 | |||||
| 2024-D0039 | Optimization of transcranial motor evoked potentials in supratentorial surgeries | clinical trial | medical devices | monocentric | A1 | Prof. Dr. med. Kathleen Seidel | Universitätsklinik für Neurochirurgie, Inselspital Bern |
Universitätsklinik für Neurochirurgie, Inselspital Bern, Bern |
Kantonale Ethikkommission Bern | 27.06.2024 | |||||
| 2024-D0037 | The DEXTER-assisted non-emergent and acute cholecystectomy Study | clinical trial | medical devices | multicentric | A1 | Prof. Dr. med. Stefan Breitenstein | Distalmotion SA |
Kantonsspital Winterthur, Winterthur Centre Hospitalier Universitaire Vaudois, Rue du Bugnon 46 Hirslanden Zurich, Chirurgisches Zentrum Zürich Witellikerstrasse 40 |
Kantonale Ethikkommission Zürich | Commission cantonale d'Éthique de la Recherche sur l'être humain Vaud (CER-VD), Kantonale Ethikkommission Zürich | 14.06.2024 | Study has ended | |||
| 2024-D0036 | A prospective, multinational, multicentre, open-label, randomised, non-inferiority trial to compare safety and effectiveness of Meril’s Myval Transcatheter Heart Valve (THV) series vs. Contemporary Va More ... | clinical trial | medical devices | monocentric | A1 | PD Dr. med. / Thomas / Nestelberger | Meril Life Sciences Pvt. Ltd. |
Universitätsspital Basel, Universitäres Herzzentrum, Basel |
Ethikkommission Nordwest- und Zentralschweiz EKNZ | 16.05.2024 | |||||
| 2024-D0035 | 20210081_Phase 3 Multicenter, Randomized, Open-label, Active-controlled Study of Sotorasib, Panitumumab and FOLFIRI Versus FOLFIRI With or Without Bevacizumab-awwb for Treatment-naïve Subjects With Me More ... | clinical trial | in vitro diagnostic medical devices IVD-MD | monocentric | C2 | Dr. med. Ralph Fritsch | AMGEN |
Universitätsspital Zürich, Zürich |
Kantonale Ethikkommission Zürich | 06.09.2024 | |||||
| 2024-D0034 | INCREASED PERI-IMPLANT BONE FORMATION AROUND SIMULTANEOUSLY GRAFTED HYDROPHILIC MICROROUGH TITANIUM IMPLANTS - AN EXPLORATORY HUMAN HISTOMETRIC ANALYSIS | clinical trial | combination drugs/devices | monocentric | A1 | Dr. Alexandre Perez | Hôpitaux Universitaires de Genève |
HUG, Genève |
Commission Cantonale d'éthique de la recherche Genève (CCER) | 26.06.2024 | |||||
| 2024-D0033 | BradycArdia paCemaKer with AV interval modulation for Blood prEssure treAtmenT (BACKBEAT Trial) | clinical trial | medical devices | multicentric | C2 | Dr. Tardu Özkartal | Orchestra Biomed |
Istituto Cardiocentro Ticino, Lugano Universitätsspital Bern, Bern University Hospital Basel, Cardiology Petersgaben 4 |
Comitato etico cantonale Ticino | Kantonale Ethikkommission Bern, Ethikkommission Nordwest- und Zentralschweiz EKNZ | 14.10.2024 | ||||
| 2024-D0028 | Telerehabilitation after a stroke: Feasibility, safety and performance evaluation of an application-based training programme for patients after a stroke in the subacute phase | clinical trial | medical devices | monocentric | C2 | PD Dr. Corina Schuster-Amft | Reha Rheinfelden |
Reha Rheinfelden, Rheinfelden |
Ethikkommission Nordwest- und Zentralschweiz EKNZ | 14.06.2024 | |||||
| 2024-D0027 | Volumetric dimensional changes after surgical pontic site development procedures with connective tissue graft or collagen matrix: A noninferiority randomized controlled trial | clinical trial | medical devices | monocentric | A1 | Dr. med. dent. Manrique Fonseca | Klinik für Rekonstruktive Zahnmedizin und Gerodontologie, Universität Bern |
Klinik für Rekonstruktive Zahnmedizin und Gerodontologie, Universität Bern, Bern |
Kantonale Ethikkommission Bern | 26.08.2024 | |||||
| 2024-D0026 |
Treatment of periodontal intra-bony defects with a volume-stable collagen matrix or deproteinized bovine bone mineral with 10% collagen. A 12-month multi-center randomized controlled trial |
clinical trial | medical devices | monocentric | A1 | Giovanni Salvi | University of Bern |
University of Bern, Berne |
Kantonale Ethikkommission Bern | 28.06.2024 | |||||
| 2024-D0025 | Clinical evaluation of a new printable denture base material: A prospective single-arm study | clinical trial | medical devices | monocentric | C2 | Dr. med. dent. Ronny Watzke | Ivoclar Vivadent AG |
Ivoclar Vivadent AG, Schaan |
Kantonale Ethikkommission Zürich | 25.06.2024 | |||||
| 2024-D0023 | Single-center prospective comparison of diagnostic performance of deep-learning agumented UTE/ZTE MRI sequences and standard-of-care low dose CT for rheumatologic patients with musculoskeletal disease | clinical trial | medical devices | monocentric | A1 | Dr. med. Falko Ensle | UniversitätsSpital Zürich, Institut für Diagnostische und Interventionelle Radiologie |
UniversitätsSpital Zürich, Institut für Diagnostische und Interventionelle Radiologie, Zürich |
Kantonale Ethikkommission Zürich | 12.07.2024 | |||||
| 2024-D0021 |
OBPM_Calfree2024 Recording of physiological data via an optical sensor at the fingertip alongside with double auscultatory and pulse oximetry to evaluate the effectiveness of an Optical Blood Pressur More ... |
clinical trial | medical devices | monocentric | C2 | Pr Grégoire WUERZNER | Aktiia SA |
CHUV, Lausanne |
Commission cantonale d'Éthique de la Recherche sur l'être humain Vaud (CER-VD) | 21.05.2024 | |||||
| 2024-D0018 | A performance evaluation study for the testing of DNA extracted from tumor tissue samples, using the therascreen® KRAS RGQ PCR Kit, from participants with Non-Small Cell Lung Cancer in Lilly’s Clinica More ... | clinical trial | in vitro diagnostic medical devices IVD-MD | multicentric | A2 | Ulrich Richer | Qiagen Manchester Limited |
University Hospital of Zurich, Zürich Cantonal Hospital Winterhur, Brauerstrasse 15, Postfach 834 CH-8401 Winterhur |
Kantonale Ethikkommission Zürich | Kantonale Ethikkommission Zürich | 28.06.2024 | ||||
| 2024-D0017 | Stabilizing mandibular overdentures with a single implant placed in the canine region of the preferred chewing side compared to the midline single-implant overdenture treatment concept: an RCT with 5 More ... | clinical trial | medical devices | monocentric | A1 | Dr Sabrina Maniewicz | Clinique universitaire de médecine dentaire |
University Clinics of Dental Medicine, Geneva |
Commission Cantonale d'éthique de la recherche Genève (CCER) | 04.12.2024 | |||||