| BASEC ID | Project title | Type of project | Type of clinical trial | Study phase (clinical trials only) | multi- / monocentric | Category | Principal investigator | Sponsor | Investigational sites | Lead EC | Local EC(s) | Approval date | Minors | Study Ended | |
|---|---|---|---|---|---|---|---|---|---|---|---|---|---|---|---|
| 2024-02210 | Association of gut and bile microbiome and hepatic inflammation in patients with cholangitis | non clinical, involving persons | monocentric | A | PD Dr. med. Sena Blümel | University Hospital Zurich |
University Hospital Zurich, Zürich |
Kantonale Ethikkommission Zürich | 04.03.2025 | ||||||
| 2024-02209 | Antimicrobial resistance of Helicobacter pylori in Zürich | non clinical, involving persons | monocentric | A | Dr. med. Bernhard Morell | Stadtspital Zürich |
Stadtspital Zürich, Zürich |
Kantonale Ethikkommission Zürich | 07.03.2025 | ||||||
| 2024-02208 | Indikation von wachstumslenkenden Operationen und deren Einfluss auf das Gangbild bei Kindern und Jugendlichen mit orthopädischen Fehlstellungen der unteren Extremitäten | personal data/biological material | monocentric | Dr. rer. nat. Nathalie Alexander | Ostschweizer Kinderspital |
Stiftung Ostschweizer Kinderspital, St. Gallen |
Ethikkommission Ostschweiz (EKOS) | 31.10.2024 | |||||||
| 2024-02207 | CPIT565B12101: A phase Ib, open-label, ascending dose study with step-up doses to assess safety, tolerability, and pharmacokinetics of PIT565 in participants with systemic lupus erythematosus (SLE) | clinical trial | drugs | phase 1 | multicentric | C | Andrea Rubbert-Roth | Novartis Pharma Schweiz AG |
Kantonsspital St. Gallen, St Gallen Inselspital, Bern |
Ethikkommission Ostschweiz (EKOS) | Kantonale Ethikkommission Bern | 19.12.2024 | |||
| 2024-02206 | Urine incontinence occurrence and sexual hormones in women with chronic spinal cord injury/disease | non clinical, involving persons | monocentric | A | Prof. Dr. med. Jürgen Pannek | Schweizer Paraplegiker-Zentrum Nottwil |
Swiss Paraplegic Centre, Nottwil |
Ethikkommission Nordwest- und Zentralschweiz EKNZ | 04.12.2024 | ||||||
| 2024-02205 | Conservative Treatment of Acute Pediatric ACL-Ruptures Following a Modified Cross-Bracing-Protocol | clinical trial | other clinical trials | monocentric | A | Dr. med. Samuel Tschudi | Universitäts Kinderspital Zürich |
Universitäts Kinderspital Zürich, Zürich |
Kantonale Ethikkommission Zürich | 01.07.2025 | yes | ||||
| 2024-02204 | Osseous healing of non-surgically treated infrabony defects and prognostic factors: a retrospective case series | personal data/biological material | monocentric | Dr. med. dent. (HU) Tobias M. Janson | Center for dental medicine |
Clinic of Conservative and Preventive Dentistry, University of Zurich, Center of Dental Medicine, Zurich |
Kantonale Ethikkommission Zürich | 17.01.2025 | |||||||
| 2024-02203 | Functional biomechanics of healthy and symptomatic temporomandibular joints | personal data/biological material | monocentric | PD Dr. Vera Colombo | Universität Zürich |
Klinik für Kaufunktionsstörungen und dentale Materialwissenschaften, Zentrum für Zahnmedizin, Universität Zürich, Zürich |
Kantonale Ethikkommission Zürich | 08.07.2025 | |||||||
| 2024-02202 | Hybrid vs. complete surgical therapy for combined coronary artery disease and aortic valve pathology | personal data/biological material | multicentric | Prof. Dr. med. Patric Biaggi |
HerzKlinik Hirslanden, 8032 Zürich HerzZentrum Hirslanden, Zürich |
Kantonale Ethikkommission Zürich | Kantonale Ethikkommission Zürich | 07.02.2025 | |||||||
| 2024-02201 | Bösch osteotomy for hallux valgus correction: clinical and radiographic outcomes in patients with cerebral palsy. | personal data/biological material | monocentric | Dr / Geraldo / De Coulon | Hôpitaux Universitaires de Genève |
HUG, Genève |
Commission Cantonale d'éthique de la recherche Genève (CCER) | 20.02.2025 | |||||||
| 2024-02200 | Qualitätssicherung und -verbesserung mittels "Quality Improvement Cycle" bei rechtsseitigen Kolonresektionen und tief anterioren Rektumresektionen - ein Vergleich mit dem internationalen Benchmark | personal data/biological material | monocentric | Dr. Michaela Ramser | Universitätsspital Zürich |
Universitätsspital Zürich, Zürich |
Kantonale Ethikkommission Zürich | 04.02.2025 | |||||||
| 2024-02199 | PROtective ventilation with FLOW–controlled ventilation to improve postoperative pulmonary outcome after ROBOT–assisted laparoscopic surgery – an international multicenter pilot randomized clinical tr More ... | clinical trial | other clinical trials | monocentric | A | Dr. med. Timur Yurttas | Kantonsspital St. Gallen |
Department of Anesthesia, Rescue- and Pain Medicine, Kantonsspital St. Gallen, St. Gallen |
Ethikkommission Ostschweiz (EKOS) | 03.07.2025 | Study has ended | ||||
| 2024-02198 | Étude rétrospective sur la corrélation entre marqueurs ALDH1 + HIF-1alpha et les images de nécrose à l’IRM et la réponse à la chimiothérapie néoadjuvante dans le cancer du sein | personal data/biological material | monocentric | Dr. Loïc Lelièvre | CHUV - DFME - Gynécologie |
Centre universitaire hospitalier vaudois, Lausanne |
Commission cantonale d'Éthique de la Recherche sur l'être humain Vaud (CER-VD) | 31.10.2025 | |||||||
| 2024-02196 | A Randomized, Double-Blinded, Placebo-Controlled, Phase 2, Parallel-Group Study to Evaluate the Efficacy, Safety, Tolerability, Pharmacodynamics, Pharmacokinetics, and Immunogenicity of Efgartigimod P More ... | clinical trial | drugs | phase 2 | multicentric | C | Prof. Dr. Frauke Förger | argenx BV |
HOCH Health Ostschweiz, Kantonsspital St. Gallen, St. Gallen Universitätsspital Zürich, Zürich |
Ethikkommission Ostschweiz (EKOS) | Kantonale Ethikkommission Zürich | 16.01.2025 | |||
| 2024-02195 | TRI0382 - Biomarker long term stability assessment of Cystatin C and creatinine in human urine | personal data/biological material | monocentric | Sandrine Kretz | Novartis Pharma AG - Biomedical Research |
Novartis Pharma AG - Biomedical Research, Basel |
Ethikkommission Nordwest- und Zentralschweiz EKNZ | 09.12.2024 | |||||||
| 2024-02194 | SURGICAL OUTCOME OF TOTALLY IMPLANTABLE VENOUS ACCESS PORTS VIA PERCUTANEOUS SUBCLAVIAN VEIN PUNCTURE PERFORMED BY RESIDENTS: A single-centre retrospective Analysis. | personal data/biological material | monocentric | PD Dr. Edin Mujagic | University Hospital Basel |
University Hospital, Basel |
Ethikkommission Nordwest- und Zentralschweiz EKNZ | 14.11.2024 | |||||||
| 2024-02193 | A Phase 3, Randomized, Double-Blind, Placebo-Controlled, 3-Arm, 3-Period Study to Assess the Efficacy and Safety of a New Formulation of Oral Cladribine Compared with Placebo in Participants with Gene More ... | clinical trial | drugs | phase 3 | monocentric | C | PD Dr. med. Robert Hoepner | Merck Healthcare KGaA |
Inselspital Bern, Universitätsspital Bern, Bern |
Kantonale Ethikkommission Bern | 23.04.2025 | ||||
| 2024-02192 | Investigating neuroplasticity associated with psilocybin-assisted and mindfulness-based relapse prevention group therapy in alcohol use disorder - an observational 7 Tesla MRI-study | non clinical, involving persons | monocentric | A | Prof. Dr. Leila M. Soravia | Universitätsklinik für Psychiatrie und Psychotherapie, Universitäre Psychiatrische Dienste, Universität Bern |
Universitätsklinik für Psychiatrie und Psychotherapie (UPD) Bern, Bern |
Kantonale Ethikkommission Bern | 06.01.2025 | ||||||
| 2024-02191 | Impact of gestational diabetes on the mother and her child during and after pregnancy | personal data/biological material | monocentric | Prof Jardena J. Puder | CHUV - DFME - Obstétrique |
CHUV, Lausanne |
Commission cantonale d'Éthique de la Recherche sur l'être humain Vaud (CER-VD) | 21.01.2025 | |||||||
| 2024-02188 | A Novel 3D Base of the Heart Transoesophageal Echocardiography View for Identifying Valve Pathology: A Comparison of 3D Images with a Gold Standard 2D transoesophageal Echocardiography Exam | personal data/biological material | multicentric | Dr.med. Isabelle Frei | Universitätsspital Basel, Departement für Anästhesie |
Universitätsspital Basel, Basel Stadtspital Zürich, Triemli, Zürich University Hospital Zurich, Zurich |
Ethikkommission Nordwest- und Zentralschweiz EKNZ | Kantonale Ethikkommission Zürich | 14.10.2025 | ||||||