| BASEC ID | Project title | Type of project | Type of clinical trial | Study phase (clinical trials only) | multi- / monocentric | Category | Principal investigator | Sponsor | Investigational sites | Lead EC | Local EC(s) | Approval date | Minors | Study Ended | |
|---|---|---|---|---|---|---|---|---|---|---|---|---|---|---|---|
| 2022-01886 | Retrospective safety study of the use of cultured epithelial autografts in severely burned patients | personal data/biological material | multicentric | Dr PD Anthony de Buys Roessingh | CHUV - Chirurgie de l'enfant |
CHUV, Lausanne University Children's Hospital Zurich, Zurich Klinik für Plastische Chirurgie und Handchirurgie, Zurich |
Commission cantonale d'Éthique de la Recherche sur l'être humain Vaud (CER-VD) | Kantonale Ethikkommission Zürich | 09.06.2023 | ||||||
| 2022-01885 | Transcutaneous compression suture with Iodine gauze for fragile wound conditions in shoulder and elbow surgery | personal data/biological material | monocentric | Dr. med. Florian Grubhofer | Universitätsklinik Balgrist |
Universitätsklink Balgrist, Zürich |
Kantonale Ethikkommission Zürich | 25.11.2022 | |||||||
| 2022-01884 | Korrelation von Patient Reported Outcome Measures mit endoskopischen Aktivitätindizes bei IBD | personal data/biological material | monocentric | Jan Hendrik Niess | Clarunis |
Clarunis, Basel |
Ethikkommission Nordwest- und Zentralschweiz EKNZ | 16.12.2022 | |||||||
| 2022-01883 | Oncological outcomes of stage IIIA, IIIB or oligo-metastatic stage IV non-small cell lung cancer treated by induction chemo-immunotherapy followed or not by surgery. | personal data/biological material | monocentric | Dr Jean Yannis Perentes | CHUV - Chirurgie thoracique |
CHUV, Lausanne |
Commission cantonale d'Éthique de la Recherche sur l'être humain Vaud (CER-VD) | 01.11.2022 | |||||||
| 2022-01882 | Functional effect of AD-associated IL-18R gene variants | non clinical, involving persons | monocentric | A | Prof. Dr. med. et. Dr. phil. nat. Christoph Schlapbach | Dept. of Dermatology, Inselspital, Bern University Hospital |
Department of Dermatology, Inselspital, Bern |
Kantonale Ethikkommission Bern | 13.01.2023 | ||||||
| 2022-01881 | Adaptation culturelle et validation psychométrique de la version française du test d’évaluation neurocognitive Six-Item Cognitive Impairment Test | non clinical, involving persons | monocentric | A | Henk Verloo | Haute École de Santé |
Haute École de Santé, HES-SO Valais/Wallis, Sion |
Commission cantonale d'Éthique de la Recherche sur l'être humain Vaud (CER-VD) | 06.04.2023 | Study has ended | |||||
| 2022-01880 | First prospective randomized trial to examine a differential therapeutic response in symptomatic pa-tients with non-obstructive coronary artery disease after coronary physiological testing - EXAMINE-C More ... | clinical trial | drugs | phase 4 | multicentric | C | Prof. Dr. med. Barbara E. Stähli | Charité – Universitätsmedizin Berlin |
Universitätsspital Zürich, Universitäres Herzzentrum Zürich, Zurich Inselspital, Universitätsspital Bern, Bern |
Kantonale Ethikkommission Zürich | Kantonale Ethikkommission Bern | 17.01.2023 | Study has ended | ||
| 2022-01879 | A Phase 1/2 Study to Evaluate the Safety, Tolerability, and Efficacy of VX-880 in Subjects Who Have Type 1 Diabetes Mellitus with Impaired Hypoglycemic Awareness and Severe Hypoglycemia | clinical trial | transplant products | monocentric | C | Dr. Fadi Haidar | Vertex Pharmaceuticals (Germany) GmbH |
Hospiteaux universitaire Geneve, Geneve |
Commission Cantonale d'éthique de la recherche Genève (CCER) | 25.01.2023 | |||||
| 2022-01878 | Pre‑emptive luminal vacuum drainage (pLVD) of the anastomotic area after upper gastrointestinal tract resection | personal data/biological material | monocentric | Prof. Dr. med. Christian Gutschow | Department of Visceral- and Transplant Surgery, University Hospital Zurich |
UniversitätsSpital Zürich, Zürich |
Kantonale Ethikkommission Zürich | 18.11.2022 | |||||||
| 2022-01877 | A PHASE IB/II RANDOMIZED, OPEN LABEL DRUG REPURPOSING TRIAL OF GLUTAMATE SIGNALING INHIBITORS IN COMBINATION WITH CHEMORADIOTHERAPY IN PATIENTS WITH NEWLY DIAGNOSED GLIOBLASTOMA (GLUGLIO) | clinical trial | drugs | phase 1/2 | multicentric | C | Dr med. Hans-Georg Wirsching | Universitätsspital Zurich |
Universitätsspital Zurich, Zurich Inselspital, University Hospital Bern, Bern University Hospital Basel, Basel Cantonal Hospital Lucerne, Luzerne University of Geneva and Geneva University Hospital, G More ... |
Kantonale Ethikkommission Zürich | Ethikkommission Nordwest- und Zentralschweiz EKNZ, Ethikkommission Ostschweiz (EKOS), Kantonale Ethikkommission Bern, Kantonale Ethikkommission Zürich, Commission cantonale d'Éthique de la Recherche s More ... | 20.12.2022 | |||
| 2022-01876 | MRI-BASED RADIOMICS MODEL FOR PROGNOSTIC PROFILING OF HUMAN PAPILLOMA VIRUS (HPV) DRIVEN CANCERS (OROPHARYNGEAL, CERVICAL AND ANO-GENITAL CANCERS) | personal data/biological material | monocentric | PD dr med Stefania Rizzo |
Ente Ospedaliero Cantonale, Lugano |
Comitato etico cantonale Ticino | 16.01.2023 | ||||||||
| 2022-01875 | Single center comparative study of Kawasaki disease in children before and during the COVID-19 pandemic | personal data/biological material | monocentric | Professeur Nicole Sekarski | CHUV - Cardiogie pédiatrique |
CHUV, Lausanne |
Commission cantonale d'Éthique de la Recherche sur l'être humain Vaud (CER-VD) | 21.02.2023 | |||||||
| 2022-01874 | Assessment of the treatment of keratoconus using customized corneal cross-linking. | clinical trial | other clinical trials | monocentric | A | Prof. Dr. Dr. Farhad Hafezi | ELZA Institute |
ELZA Institute AG, Dietikon |
Kantonale Ethikkommission Zürich | 07.02.2023 | yes | ||||
| 2022-01873 | “To what extend are perceptual deficits caused by ophthalmological factors? An investigation in patients undergoing cataract surgery” | non clinical, involving persons | monocentric | A | Dr. Hanna Zuche | LPSY, BMI, EPFL |
Universitätsspital Basel, Augenklinik, Basel |
Ethikkommission Nordwest- und Zentralschweiz EKNZ | 22.11.2022 | Study has ended | |||||
| 2022-01872 | Correlation of Anatomic and Measured Specific Knee Footprints using Compressed Lateral and anteroposterior Anatomical Systematic Sequence (“CLASS”) | deceased persons | monocentric | Dr.med. Grégoire Thürig | Department Orthopedic Surgery and Traumatology, HFR cantonal Hospital Fribourg, University of Fribourg |
Orthopädie - HFR, Fribourg |
Commission cantonale d'Éthique de la Recherche sur l'être humain Vaud (CER-VD) | 30.11.2022 | |||||||
| 2022-01871 | Heart Rate Variability, Physical Activity and Exhaustion in the Inpatient Treatment of Stress-Related Disorders - HARMODI. | non clinical, involving persons | monocentric | A | Dr. Thomas Russmann | Department Sport, Exercise and Health, University Basel |
Clinica Holistica Engiadina, Susch |
Kantonale Ethikkommission Zürich | 22.12.2022 | Study has ended | |||||
| 2022-01870 | Sodium lactate versus Hypertonic Saline Solution in the treatment of intracranial hypertensive episodes in severe brain-injured patients. SLHYSS study | clinical trial | drugs | phase 3 | monocentric | C | Pr Hervé QUINTARD | HUG |
HUG, Gèneve |
Commission Cantonale d'éthique de la recherche Genève (CCER) | 17.01.2023 | ||||
| 2022-01869 | Feasibility study on the use of Redormin® 500 (Ze 91019) on day-time cognition and quality of life in people with occasional sleep problems | clinical trial | drugs | phase 4 | monocentric | B | Dr. Christiane Gerhards | Zeller Medical AG |
University of Basel, Basel |
Ethikkommission Nordwest- und Zentralschweiz EKNZ | 25.11.2022 | Study has ended | |||
| 2022-01868 | An Open-Label Extension Study to Assess the Safety, Tolerability, and Effectiveness of the Long-Term use of Treprostinil Palmitil Inhalation Powder in Participants with Pulmonary Arterial Hypertension | clinical trial | drugs | phase 2 | monocentric | C | Dr Benoît Lechartier | Insmed Switzerland GmbH |
CHUV, Lausanne |
Commission cantonale d'Éthique de la Recherche sur l'être humain Vaud (CER-VD) | 27.01.2023 | ||||
| 2022-01866 | A 2-Part Seamless Part A (Phase 2)/Part B (Phase 3) Randomized, Double-Blind, Placebo-Controlled, Multicenter Study to Evaluate the Efficacy and Safety of BIIB059 in Participants with Active Subacute More ... | clinical trial | drugs | phase 3 | multicentric | C | Prof. Antonio Cozzio | Biogen Idec Research Limited |
Kantonsspital St. Gallen, St. Gallen Centre Hospitalier Universitaire Vaudois (CHUV), Lausanne Universitätsspital Zürich, Dermatologische Klinik, Zürich |
Ethikkommission Ostschweiz (EKOS) | Kantonale Ethikkommission Zürich, Commission cantonale d'Éthique de la Recherche sur l'être humain Vaud (CER-VD) | 22.12.2022 | |||