| BASEC ID | Project title | Type of project | Type of clinical trial | Study phase (clinical trials only) | multi- / monocentric | Category | Principal investigator | Sponsor | Investigational sites | Lead EC | Local EC(s) | Approval date | Minors | Study Ended | |
|---|---|---|---|---|---|---|---|---|---|---|---|---|---|---|---|
| 2021-02162 | Investigating the molecular mechanisms of the ADP-ribosyltransferase PARP6 in manifestation and progression of heart failure | personal data/biological material | monocentric | Prof/Michael/Hottiger | University of Zurich |
University of Zurich, Zurich |
Kantonale Ethikkommission Zürich | 01.03.2022 | |||||||
| 2021-02161 |
20170104_A Phase 2, Dose-finding, Randomized, Double-blind, Placebo-controlled, Multicenter Study to Evaluate the Safety and Efficacy of Efavaleukin Alfa Induction Therapy in Subjects with Mod More ... |
clinical trial | drugs | phase 2 | multicentric | C | Dr. Biedermann Luc | One Amgen Center Drive Thousand Oaks, CA 91320 |
Universitätsspital Zürich, Zürich Intesto BE, Bern Inselspital Bern, Bern Kantonsspital St. Gallen, St. Gallen |
Kantonale Ethikkommission Zürich | Ethikkommission Ostschweiz (EKOS), Kantonale Ethikkommission Bern | 07.01.2022 | |||
| 2021-02160 | Understanding the pathomechanisms leading to Autophagic Vacuolar Myopathies | personal data/biological material | monocentric | Prof. Perrine CASTETS | Centre Médical Universitaire |
CMU, Faculté de Médecine, Genève |
Commission Cantonale d'éthique de la recherche Genève (CCER) | 02.11.2021 | |||||||
| 2021-02159 | Untersuchung von Stromazellen und Immunzellen im Knochenmark von Patienten mit akuter myeloischer Leukämie zur Charakterisierung der Mikroumgebung und Identifikation neuer Therapiestrategien | non clinical, involving persons | monocentric | A | Prof. Dr. med. Markus Manz |
Universitätsspital Zürich, Zürich |
Kantonale Ethikkommission Zürich | 23.11.2021 | |||||||
| 2021-02158 |
ENTYVIO® Real-World Outcomes in Bio-naïve Crohn’s Disease Patients in Belgium, Australia, and Switzerland: An EVOLVE Observational Expansion Study |
personal data/biological material | multicentric | Michael Scharl | Takeda Development Center Americas, Inc. (TDC Americas) |
Universitätsspital Zürich, Zürich Inselspital Bern, Bern Berner IBD Study Group c/o Intesto KLG, Gastroenterologische Praxis, Crohn-Colitis-Zentrum, Bern Clarunis Universitäres Bauchzenturm Basel, Bas More ... |
Kantonale Ethikkommission Zürich | Ethikkommission Nordwest- und Zentralschweiz EKNZ, Kantonale Ethikkommission Bern, Kantonale Ethikkommission Zürich | 14.01.2022 | Study has ended | |||||
| 2021-02157 | Randomised, double-blind, placebo-controlled and parallel group trial to investigate the effects of two doses (up-titration to a fixed dose regimen) of oral BI 685509 on portal hypertension after 24 w More ... | clinical trial | drugs | phase 2 | multicentric | C | Prof. Dr. Markus Heim | Boehringer Ingelheim RCV GmbH & Co KG |
Universitätsspital Basel, Clarunis Universitäres Bauchzentrum, Basel Ente Ospedaliero Cantonale, Servicio di Gastroenterologia e Epatologia, Ospedale Italiano di Lugano, 6962 Lugano-Viganello |
Ethikkommission Nordwest- und Zentralschweiz EKNZ | Comitato etico cantonale Ticino | 08.02.2022 | |||
| 2021-02155 |
A PHASE 3, MULTICENTER, MULTINATIONAL, OPEN-LABEL EXTENSION STUDY TO EVALUATE THE LONG-TERM SAFETY OF CC-93538 IN ADULT AND ADOLESCENT SUBJECTS WITH EOSINOPHILIC ESOPHAGITIS |
clinical trial | drugs | phase 3 | multicentric | C | Prof. Alain Schoepfer | Celgene International II Sàrl |
FMH Medicine Interne, Lausanne Kantonsspital Baselland, Liestal |
Commission cantonale d'Éthique de la Recherche sur l'être humain Vaud (CER-VD) | Ethikkommission Nordwest- und Zentralschweiz EKNZ | 16.03.2023 | |||
| 2021-02153 | Appropriateness of in-hospital intravenous iron therapy in a Swiss tertiary care hospital – a quality control study | personal data/biological material | monocentric | PD Dr. med. Michael Osthoff | Universitätsspital Basel |
Universitätsspital Basel, Basel |
Ethikkommission Nordwest- und Zentralschweiz EKNZ | 18.11.2021 | |||||||
| 2021-02152 | Regard croisé du physiothérapeute et du patient avec une lombalgie chronique non spécifique sur la communication verbale autour de la douleur. | non clinical, involving persons | monocentric | A | Claude Pichonnaz | Haute école de Santé Vaud |
HESAV and CHUV, Lausanne |
Commission cantonale d'Éthique de la Recherche sur l'être humain Vaud (CER-VD) | 06.01.2022 | Study has ended | |||||
| 2021-02151 | Metabolic Bone Disease in Children with prolonged stay in Intensive Care Units (ICU) | personal data/biological material | monocentric | PD Dr. med. Giuseppina Spartà | Universitäts-Kinderspital Zürich |
Universitäts-Kinderspital Zürich, Zürich |
Kantonale Ethikkommission Zürich | 14.12.2021 | |||||||
| 2021-02150 |
Betreuungs- und begegnungsfreie Zeiträume: Methodenplurale Erkundungen zum Erleben von Personen mit Demenz Times without care and encounters: Exploring the experiences of persons with dementia: More ... |
non clinical, involving persons | monocentric | A | Prof. Dr. Thomas Beer | Ost - Ostschweizer Fachhochschule |
OST - Ostschweizer Fachhochschule, St.Gallen |
Ethikkommission Ostschweiz (EKOS) | 09.12.2021 | ||||||
| 2021-02147 | ML42393 - IMPACT OF OCRELIZUMAB ON PATIENT REPORTED FATIGUE AND QUALITY OF LIFE IN RMS PATIENTS TREATED FOR THE FIRST TIME WITH OCRELIZUMAB (MOOZART): AN OBSERVATIONAL STUDY | non clinical, involving persons | multicentric | A | PD Dr. med. Robert Hoepner | Roche Pharma (Schweiz) AG |
Inselspital, Universitätsspital Bern, Bern Luzerner Kantonsspital, Luzern Ospedale Regionale di Lugano, Lugano |
Kantonale Ethikkommission Bern | Ethikkommission Nordwest- und Zentralschweiz EKNZ, Comitato etico cantonale Ticino | 14.02.2022 | |||||
| 2021-02145 | Estimating Time to Deterioration Using Artificial Intelligence to Avoid Overtreatment of Patients with Brain Metastases during the End of Life Phase | personal data/biological material | monocentric | PD Robert Förster | Institut für Radioonkologie, Kantonsspital Winterthur |
Institut für Radioonkologie, Kantonsspital Winterthur, Winterthur |
Kantonale Ethikkommission Zürich | 22.11.2021 | |||||||
| 2021-02144 | The bioavailability and effect on pouch pH of esomeprazole as tablets or in solution after laparoscopic proximal RYGB for morbid obesity – an investigator blinded pilot study | clinical trial | drugs | phase 4 | monocentric | A | Prof. Dr. Urs Zingg | Spital Limmattal |
Spital Limmattal, Schlieren |
Kantonale Ethikkommission Zürich | 17.12.2021 | ||||
| 2021-02142 | Ischaemic PReconditioning In Non Cardiac surgEry (PRINCE trial) | clinical trial | other clinical trials | monocentric | B | PD Dr. med. Christoph Czarnetzki | IRCCS Ospedale San Raffaele |
Ospedale Regionale di Lugano, Lugano |
Comitato etico cantonale Ticino | 04.04.2022 | |||||
| 2021-02141 | Evaluation of cellular functions triggered by antibodies against the SARS-CoV-2 spike protein | non clinical, involving persons | monocentric | A | Prof. Jörg D. Seebach | University Hospitals Geneva and Medical Faculty |
University Hospitals Geneva and Medical Faculty, Geneva |
Commission Cantonale d'éthique de la recherche Genève (CCER) | 30.11.2021 | ||||||
| 2021-02140 | Fast-track in the Emergency Department for wrist and scaphoid fractures: a randomized trial | clinical trial | other clinical trials | monocentric | A | Dr.med Laura Uccella | EOC |
EOC, Lugano |
Comitato etico cantonale Ticino | 03.12.2021 | |||||
| 2021-02139 | Percutaneous Fogarty® thrombectomy using large bore sheaths – a novel technique with indefinite possibilities | personal data/biological material | monocentric | PD Dr. Edin Mujagic | Universitätsspital Basel |
Universitätsspital, Basel |
Ethikkommission Nordwest- und Zentralschweiz EKNZ | 17.11.2021 | |||||||
| 2021-02138 | Analysis of potential clinicopathological prognostic factors in patients with cutaneous melanoma at stage IIIA, to more accurately identify groups at higher and lower risk of disease progression. | personal data/biological material | monocentric | Dr. Vittoria Espeli | Melanoma & Sarcoma Surgical Unit |
IOSI, Bellinzona |
Comitato etico cantonale Ticino | 25.10.2022 | |||||||
| 2021-02137 | Etude in vitro de l’effet du PRP et PRP-HA (dispositifs CuteCellTM) sur la prolifération des cellules de muqueuse vaginale (HMVG) isolées à partir d’un prélèvement de tissu vaginal obtenu lors d’une More ... | non clinical, involving persons | monocentric | A | Prof Patrick Dällenbach | RegenLab |
HUG, Genève |
Commission Cantonale d'éthique de la recherche Genève (CCER) | 30.03.2022 | ||||||