BASEC ID Project title Type of project Type of clinical trial Study phase (clinical trials only) multi- / monocentric Category Principal investigator Sponsor Investigational sites Lead EC Local EC(s) Approval date Minors Study Ended
2022-00177 DynamoMet: Daily dynamics of metabolic rate in healthy adults in an office case study non clinical, involving persons monocentric A Assist. Prof. Dolaana KHOVALYG EPFL EPFL, Fribourg
Commission cantonale d'Éthique de la Recherche sur l'être humain Vaud (CER-VD) 21.03.2022 Study has ended
2022-00175 A Global, Phase 2 Study of ARX788 in HER2-positive Metastatic Breast Cancer Patients Whose Disease is Resistant or Refractory to T-DM1, and/or T-DXd, and/or Tucatinib-containing Regimens clinical trial drugs phase 2 multicentric C Dr. Müller Ambrx, Inc. Kantonsspital Winterthur, Winterthur
Hopitaux Universitaires de Genève, Genève
Kantonale Ethikkommission Zürich Commission Cantonale d'éthique de la recherche Genève (CCER) 12.07.2022 Study has ended
2022-00174 Mind-body online therapy in a somatic setting - a randomized-controlled, two-arm, multicenter study in oncologic gynecology clinical trial other clinical trials monocentric A Dr. phil. Katja Hämmerli Keller Kantonsspital St.Gallen Kantonsspital St.Gallen, CH-9007 St.Gallen
Ethikkommission Ostschweiz (EKOS) 21.07.2022 Study has ended
2022-00173 Comparaison du frottis nasopharyngé versus frottis salivaire pour la détection de la variante Omicron du SARS-CoV-2 (OMICRON) non clinical, involving persons monocentric A Dr/Antonios/Kritikos CHUV CHUV, Lausanne
Commission cantonale d'Éthique de la Recherche sur l'être humain Vaud (CER-VD) 02.02.2022 Study has ended
2022-00171 Rôle des peptides natriurétiques dans l'histoire naturelle du syndrome de Marfan. non clinical, involving persons monocentric A Prof. Lucia Mazzolai CHUV - Angiologie CHUV, Lausanne
Commission cantonale d'Éthique de la Recherche sur l'être humain Vaud (CER-VD) 06.05.2022
2022-00169 Gait pattern during preferred walking speed in patients with lipedema non clinical, involving persons monocentric A Prof Lucia Mazzolai CHUV - Angiologie Service d'angiologie, CHUV, Lausanne
Commission cantonale d'Éthique de la Recherche sur l'être humain Vaud (CER-VD) 28.02.2022
2022-00168 A single-center, patient-blinded, randomized, 2-year, parallel-group, superiority study to compare the efficacy of augmented ACL integration via platelet-rich-plasma enriched collected autologous bone More ... clinical trial other clinical trials monocentric B Prof. Dr. med. Gian Salzmann Schulthess Klinik Schulthess Klinik, Zürich
Kantonale Ethikkommission Zürich 20.05.2022
2022-00167 A Phase 3 Double-blind, Randomized, Placebo-controlled Study Evaluating the Efficacy and Safety of ELX/TEZ/IVA in Cystic Fibrosis Subjects 6 Years of Age and Older With a Non-F508del ELX/TEZ/IVA-respo More ... clinical trial drugs phase 3 monocentric C Prof. Dr. med. Alexander Möller Vertex Pharmaceuticals (Germany) GmbH Universitäts-Kinderspital, Zürich
Kantonale Ethikkommission Zürich 10.05.2022 yes Study has ended
2022-00166 Personalized rehabilitation system using gamification with virtual reality technology: a feasibility study. clinical trial other clinical trials monocentric A Dr. Alexandre Lädermann Artanim Foundation La Tour hospital, Meyrin
Commission Cantonale d'éthique de la recherche Genève (CCER) 03.03.2022
2022-00165 Microbiome Variations in Molecular Subtypes of Muscle Invasive Bladder Cancer personal data/biological material monocentric PD Dr. med. Cédric Poyet Departement of Urology Universitätsspital Zürich, Zürich
Kantonale Ethikkommission Zürich 08.03.2022
2022-00163 Clinical implications of endogenous carbon monoxide production during extracorporeal membrane oxygenation personal data/biological material monocentric Prof. Dr. med. Sascha David Universitätsspital Zürich Institut für Intensivmedizin, Universitätsspital Zürich, Zürich
Kantonale Ethikkommission Zürich 18.03.2022
2022-00162 Combined beta- plus Auger electron therapy using a novel somatostatin receptor subtype 2 antagonist labelled with terbium-161 (161Tb-DOTA-LM3): Beta plus Study clinical trial drugs n/a monocentric C Dr. med. Julia Fricke Universitätsspital Basel Division of Nuclear Medicine, University Hospital of Basel, Basel
Ethikkommission Nordwest- und Zentralschweiz EKNZ 31.03.2022
2022-00160 The effect of cooling with a bed topper and linen on itch in clinical routine - an exploratory study clinical trial other clinical trials monocentric A PD Dr. med. Simon Mueller University Hospital Basel University Hospital Basel, Basel
Ethikkommission Nordwest- und Zentralschweiz EKNZ 22.03.2022
2022-00159 Analysis of plasma proteins associated to DNA repair in Alzheimer’s disease personal data/biological material monocentric PD Dr. Paolo Paganetti Laboratori di Ricerca Traslazionale EOC Laboratori di Ricerca Traslazionale EOC, Bellinzona
Comitato etico cantonale Ticino 18.02.2022
2022-00158 Kesimpta® (Ofatumumab) in Swiss Multiple sclerosis patients – an Observational Study (KOSMOS) non clinical, involving persons multicentric A Dr. Petra Stellmes Novartis Pharma Schweiz AG Neurologie Loewenplatz, Luzern
Inselspital Bern Universitätsklinik für Neurologie, Bern
Luzerner Kantonspital, Luzern
Neurobaden Praxis für Neurologie, Baden-Dättwil
Neurologische Praxis Zug, Zug
Neur More ...
Ethikkommission Nordwest- und Zentralschweiz EKNZ Ethikkommission Nordwest- und Zentralschweiz EKNZ, Ethikkommission Ostschweiz (EKOS), Kantonale Ethikkommission Bern, Kantonale Ethikkommission Zürich, Commission cantonale d'Éthique de la Recherche s More ... 16.03.2022
2022-00157 PRophylactic cerebral Irradiation or active MAgnetic resonance imaging surveillance in small-cell Lung cancer patients (PRIMALung study) clinical trial other clinical trials multicentric A Andratschke Nicolaus European Organisation for Research and Treatment of Cancer (EORTC) UniversitaetsSpital Zurich, Zurich
Inselspital, Bern University Hospital, Bern
Kantonsspital St Gallen, St Gallen
Reseau Hospitalier Neuchatelois - RHNe - La Chaux de Fonds, La Chaux-de-Fonds
Kantonale Ethikkommission Zürich Ethikkommission Ostschweiz (EKOS), Kantonale Ethikkommission Bern, Commission cantonale d'Éthique de la Recherche sur l'être humain Vaud (CER-VD) 01.07.2022
2022-00156 Assessment of reward responses to oral erythritol using flavor preference learning and its effects on gastrointestinal hormones, glycemic control, appetite-related sensations and emotional state clinical trial other clinical trials monocentric A PD Dr. Anne Christin Meyer-Gerspach St. Clara Research Ltd St. Clara Research Ltd, Basel
Ethikkommission Nordwest- und Zentralschweiz EKNZ 25.02.2022 Study has ended
2022-00155 Two cohort registry study for patients with advanced CSCC treated
with Cemiplimab or other approaches
non clinical, involving persons multicentric A M.D. Egle Ramelyte sanofi-aventis (schweiz) ag GUSZ Flughafen Dermatologische Klinik, 8058 Zürich
Insel Gruppe AG, Universitätsklinik für Dermatologie, Freiburgstrasse, Bern
Kantonspital Aarau AG, Aarau
Universitätsspital, Basel
Kantonsspital, St. More ...
Kantonale Ethikkommission Zürich Ethikkommission Nordwest- und Zentralschweiz EKNZ, Ethikkommission Ostschweiz (EKOS), Kantonale Ethikkommission Bern 04.03.2022
2022-00153 Analysis of clinical-pathological features and response to treatments in an international cohort of patients affected by NUTM1-rearranged carcinomas: a multicentric retrospective observational study personal data/biological material monocentric PD Dr. Med. Anastasios Stathis Fondazione IRCCS Istituto Nazionale dei Tumori di Milano Istituto Oncologico della Svizzera Italiana, Bellinzona
Comitato etico cantonale Ticino 16.02.2022
2022-00152 Biomechanical Comparison of Anterior Cruciate Ligament Reconstruction Using a Single Bundle Round or Ribbon-Like Hamstring Graft deceased persons monocentric PD Dr med Peter Koch Gelenkzentrum Winterthur AG numex GmbH, Winterhur
Kantonale Ethikkommission Zürich 04.03.2022