| BASEC ID | Project title | Type of project | Type of clinical trial | Study phase (clinical trials only) | multi- / monocentric | Category | Principal investigator | Sponsor | Investigational sites | Lead EC | Local EC(s) | Approval date | Minors | Study Ended | |
|---|---|---|---|---|---|---|---|---|---|---|---|---|---|---|---|
| 2023-01390 | A Phase 3 Randomized Clinical Study of MK-4280A (coformulated favezelimab [MK-4280] plus pembrolizumab [MK-3475]) Versus Physician’s Choice Chemotherapy in PD-(L)1-refractory, Relapsed or Refractory C More ... | clinical trial | drugs | phase 3 | monocentric | C | Dr. med. Maria Pirosa | Merck Sharp & Dohme LLC, a subsidiary of Merck & Co., Inc. |
Ente Ospedaliero Cantonale (EOC) Istituto Oncologico della Svizzera Italiana (IOSI), Bellinzona |
Comitato etico cantonale Ticino | 06.10.2023 | ||||
| 2023-01389 | Does sarcopenia affect survival or outcomes in patients with bone sarcomas? | personal data/biological material | monocentric | Docteur Fabio Becce |
CHUV, Lausanne |
Commission cantonale d'Éthique de la Recherche sur l'être humain Vaud (CER-VD) | 14.08.2023 | Study has ended | |||||||
| 2023-01388 | Individual renal unit sampling in patients with recurrent unilateral nephro- and ureterolithiasis to identify unilateral renal metabolic defects | non clinical, involving persons | monocentric | A | Dr Kevin Stritt | CHUV |
CHUV, Lausanne |
Commission cantonale d'Éthique de la Recherche sur l'être humain Vaud (CER-VD) | 27.11.2023 | Study has ended | |||||
| 2023-01387 |
A Multi-Centre, Randomised, Double-Blind, Placebo-Controlled Trial of the Safety and Efficacy of the Oral NLRP3 Inhibitor Dapansutrile in Subjects with Type 2 Diabetes Mellitus (Dapan-Dia-Study) Prot More ... |
clinical trial | drugs | phase 2 | multicentric | C | Prof. Dr. med. Marc Y. Donath | Kantonsspital Baden AG |
Kantonsspital Baden AG, Baden Stoffwechselzentrum, Kantonsspital Olten, 4600 Olten Universitätsspital Zürich, Klinik für Endokrinologie, Diabetologie und Klinische Ernährung, 8091 Zürich |
Ethikkommission Nordwest- und Zentralschweiz EKNZ | Ethikkommission Nordwest- und Zentralschweiz EKNZ, Kantonale Ethikkommission Zürich | 24.01.2024 | |||
| 2023-01385 | The first epileptic seizure: new insights into diagnosis and treatment, a 30-year monocentric population based study | personal data/biological material | monocentric | Pre Margitta Seeck | Neurology division - Hôpitaux Universitaires de Genève |
Hôpitaux Universitaires de Genève, Geneva |
Commission Cantonale d'éthique de la recherche Genève (CCER) | 13.11.2023 | |||||||
| 2023-01384 | Comparison of capillary and venous blood for nutritional and environmental biomonitoring studies | non clinical, involving persons | monocentric | A | Dr Serge Rezzi | OSAV |
SNHf, Epalinges |
Commission cantonale d'Éthique de la Recherche sur l'être humain Vaud (CER-VD) | 31.10.2023 | Study has ended | |||||
| 2023-01382 | Sustained effort network for treatment of status epilepticus/European Academy of Neurology Registry on adult refractory Status Epilepticus (SENSE-II/AROUSE) | personal data/biological material | monocentric | Dr. Pia De Stefano |
University Hospitals of Geneva, Geneva |
Commission Cantonale d'éthique de la recherche Genève (CCER) | 27.05.2025 | ||||||||
| 2023-01381 | Prevalence and clinical correlates of clinical red flags for rare diseases in patients presenting with HCM phenotype | personal data/biological material | monocentric | Dr. Niccolo' Maurizi | Centre Universitaire Hospitalier Vaudoise |
CHUV University Hospital, Lausanne |
Commission cantonale d'Éthique de la Recherche sur l'être humain Vaud (CER-VD) | 08.02.2024 | Study has ended | ||||||
| 2023-01380 | Monitored effects of physical activity on fetal heart rate by using a wireless non-invasive device | clinical trial | other clinical trials | multicentric | A | Dr. med. N. Wieloch | Universitätsklinik Balgrist |
Balgrist University Hospital, Zurich University Hospital Zurich, Zurich |
Kantonale Ethikkommission Zürich | Kantonale Ethikkommission Zürich | 04.06.2024 | ||||
| 2023-01379 | Influence of extracorporeal devices on serum levels of antimicrobial substances in the intensive care unit | personal data/biological material | monocentric | PD Dr. med. Daniel Hofmänner | University Hospital Zurich |
University Hospital Zurich, Zurich |
Kantonale Ethikkommission Zürich | 29.09.2023 | |||||||
| 2023-01378 | Model Trial Pretrial Detention | clinical trial | other clinical trials | monocentric | A | Andreas Beerli | ETH Zürich |
ETH Zurich, Zürich |
Kantonale Ethikkommission Zürich | 29.09.2023 | |||||
| 2023-01377 | Longitudinal Monitoring during different Intermittent Fasting Protocols in Obese Adults | clinical trial | other clinical trials | monocentric | A | Prof. Dr. med. Philipp Gerber | Department of Endocrinology, Diabetology and Clinical Nutrition, University Hospital Zurich |
University Hospital Zurich, Zurich |
Kantonale Ethikkommission Zürich | 07.11.2023 | |||||
| 2023-01376 | Influence of femorotibial rotation on patellofemoral stabilizing surgery: radiological and clinical outcomes | personal data/biological material | monocentric | Prof. Dr. med. Sandro Fucentese | Universitätsklinik Balgrist |
Universitätsklinik Balgrist, Zürich |
Kantonale Ethikkommission Zürich | 01.09.2023 | |||||||
| 2023-01375 | Presentations due to priapism in a University Hospital in Switzerland | personal data/biological material | monocentric | Prof. Dr. med. Evangelia Liakoni | Inselspital |
Inselspital, Bern |
Kantonale Ethikkommission Bern | 22.08.2023 | |||||||
| 2023-01374 | The effect of preoperative embolization in giant cell tumors of the bone localized in the iliosacral region of the pelvis | personal data/biological material | monocentric | PD Dr. med. Daniel Müller | Universitätsklinik Balgrist |
Universitätsklinik Balgrist, Zürich |
Kantonale Ethikkommission Zürich | 01.09.2023 | |||||||
| 2023-01373 | Analyse rétrospective de revues de polymédication en gériatrie : association entre les interactions médicamenteuses et les médicaments potentiellement inappropriés | personal data/biological material | monocentric | Dr Victoria Rollason |
Hôpitaux universitaires de Genève - HUG, Geneva |
Commission Cantonale d'éthique de la recherche Genève (CCER) | 12.09.2023 | ||||||||
| 2023-01372 | Retrospective analysis of flowcytometry data of patients with myeloid neoplasms to identify common co-expression profiles as targets for future therapies | personal data/biological material | monocentric | Dr. med. Astrid Beerlage | University Basel |
University Basel, Basel |
Ethikkommission Nordwest- und Zentralschweiz EKNZ | 07.08.2023 | |||||||
| 2023-01371 | Être âgé.e.s et vivre avec le cancer : Savoirs expérientiels et trajectoires longues des 70 ans et plus | non clinical, involving persons | monocentric | A | Rose-Anna Foley | Haute Ecole de Santé Vaud |
Haute Ecole de Santé Vaud, Lausanne |
Commission cantonale d'Éthique de la Recherche sur l'être humain Vaud (CER-VD) | 16.01.2024 | ||||||
| 2023-01370 |
The curious brain explored with 7T MRI: Dissecting the neurocomputational mechanisms of curiosity and rewards, and their impact on incidental learning through high resolution imaging |
non clinical, involving persons | monocentric | A | Dr. Giovanni Leone | Université de Genève |
Université de Genève, Geneva |
Commission Cantonale d'éthique de la recherche Genève (CCER) | 21.03.2024 | ||||||
| 2023-01369 | The UROPOT Trial, a multicentric, randomised, double-blind phase I/II trial for metabolism-based potentiation antimicrobial prophylaxis in the urological tract. | clinical trial | drugs | phase 1/2 | multicentric | B | Dr Kevin Stritt | CHUV Centre hospitalier universitaire vaudois |
CHUV, Lausanne Urology Department, Universitätsklinik für Urologie, Inselspital, Bern |
Commission cantonale d'Éthique de la Recherche sur l'être humain Vaud (CER-VD) | Kantonale Ethikkommission Bern | 09.11.2023 | |||