| BASEC ID | Project title | Type of project | Type of clinical trial | Study phase (clinical trials only) | multi- / monocentric | Category | Principal investigator | Sponsor | Investigational sites | Lead EC | Local EC(s) | Approval date | Minors | Study Ended | |
|---|---|---|---|---|---|---|---|---|---|---|---|---|---|---|---|
| 2022-01516 | A Dose-Escalation and Expansion Study of the Safety and Efficacy of XL092 in Combination with Immuno-Oncology Agents in Subjects with Unresectable Advanced or Metastatic Solid Tumors | clinical trial | drugs | phase 1 | multicentric | C | PD Dr. med. Richard Cathomas | Exelixis, Inc. |
Kantonsspital Graubünden, Chur Kantonspital St. Gallen, St. Gallen Medizinische Onkologie und Hämatologie Kantonspital Winterthur, Winterthur |
Kantonale Ethikkommission Zürich | Ethikkommission Ostschweiz (EKOS), Kantonale Ethikkommission Zürich | 29.11.2022 | |||
| 2022-01515 | Molecular imaging study of harmine/DMT: a basic research approach | clinical trial | other clinical trials | multicentric | B | Prof. Dr. Paul Cumming | Bern University Hospital |
Inselspital Bern, Universitätsklinik für Nuklearmedizin, Bern Department of Psychiatry, Psychotherapy and Psychosomatics, Psychiatric University Hospital Zurich, University of Zurich, Zurich |
Kantonale Ethikkommission Bern | Kantonale Ethikkommission Zürich | 20.01.2023 | ||||
| 2022-01514 | Utilizing fresh tumor explants for RNA sequencing and establishment of ex vivo models for the assessment of the activity of cancer immunotherapy agents | personal data/biological material | monocentric | Professor Mitch Levesque | Roche Glycart AG |
Department of Dermatology, Skin Cancer Center, University Hospital Zurich, Schlieren |
Kantonale Ethikkommission Zürich | 25.10.2022 | |||||||
| 2022-01513 | Impact du lichen scléreux vulvaire sur la sexualité féminine et amélioration de la prise en charge des patientes atteintes. | non clinical, involving persons | monocentric | A | Dre Martine Jacot-Guillarmod | CHUV |
CHUV, Lausanne |
Commission cantonale d'Éthique de la Recherche sur l'être humain Vaud (CER-VD) | 25.11.2022 | ||||||
| 2022-01512 | DFO - Antibiotische Therapie in Infektionen des diabetischen Fusssyndroms | personal data/biological material | monocentric | Dr Noémie Reinert | USB |
USB, Basel |
Ethikkommission Nordwest- und Zentralschweiz EKNZ | 12.10.2022 | |||||||
| 2022-01511 | GaitClass - Classification of gait patterns of patients with different degenerative diseases | personal data/biological material | monocentric | Prof. Dr. habil. Annegret Mündermann | University Hospital Basel |
University Hospital Basel, Basel |
Ethikkommission Nordwest- und Zentralschweiz EKNZ | 15.09.2022 | |||||||
| 2022-01510 | Determining postoperative recovery and the impact of adverse events in neurosurgery based on self-reported, app-based longitudinal assessment – a collaborative observational research project | non clinical, involving persons | multicentric | A | PD Dr. Martin N. Stienen | Kantonsspital St. Gallen |
Kantonsspital St.Gallen, St.Gallen UniversitätsSpital Zürich, Zürich |
Ethikkommission Ostschweiz (EKOS) | Kantonale Ethikkommission Zürich | 13.10.2022 | |||||
| 2022-01508 | MRI-basierte 3D Morphologie der Hüfte bei gesunden Proband:innen | non clinical, involving persons | monocentric | A | PD Dr. med. Simon D. Steppacher | Inselpsital Bern |
Department of Orthopaedic Surgery and Traumatology, Bern |
Kantonale Ethikkommission Bern | 17.10.2022 | ||||||
| 2022-01507 | Termination of long-term immunosuppressive therapy in paediatric onset inflammatory bowel disease | personal data/biological material | monocentric | Prof. Dr. Carsten Posovszky | Universitäts Kinderspital Zürich - Eleonorenstiftung |
Universitäts Kinderspital Zürich - Eleonorenstiftung, Zürich |
Kantonale Ethikkommission Zürich | 21.09.2022 | |||||||
| 2022-01506 | Ultrasonographical measurement of the intra-scaphoid angle | non clinical, involving persons | monocentric | A | Dr. Mauro Maniglio | CHUV |
CHUV - Centre hospitalier universitaire vaudois, Lausanne |
Commission cantonale d'Éthique de la Recherche sur l'être humain Vaud (CER-VD) | 22.12.2022 | ||||||
| 2022-01505 | Zygomaimplantat Nachkontrollen bei 82 Patienten über 14 Jahre | non clinical, involving persons | monocentric | A | PD Dr. Dr Dennis Rohner |
CFC Zentrum für Kiefer- und Gesichtschirurgie, Aarau |
Ethikkommission Nordwest- und Zentralschweiz EKNZ | 06.12.2022 | |||||||
| 2022-01503 | Tattoo and adult congenital heart disease: Is my heart disease my motivation having a tattoo? | non clinical, involving persons | monocentric | A | Mr. Tobias Rutz | Centre Hospitalier Universitaire Vaudois, Centre de Recherche Clinique |
Centre Hospitalier Universitaire Vaudois, Lausanne |
Commission cantonale d'Éthique de la Recherche sur l'être humain Vaud (CER-VD) | 19.01.2023 | ||||||
| 2022-01501 | A Phase 1b Proof of Concept Study to Evaluate the Safety, Tolerability, Pharmacokinetics, Pharmacodynamics, and Preliminary Efficacy of OMS906 in PNH Patients with a Sub-optimal Response to the C5 Inh More ... | clinical trial | drugs | phase 1 | monocentric | C | Dr Mathilde Gavillet-Marion | Omeros Corporation |
Lausanne University Hospital CHUV, Lausanne |
Commission cantonale d'Éthique de la Recherche sur l'être humain Vaud (CER-VD) | 16.01.2023 | ||||
| 2022-01499 | A Retrospective Analysis of Patients with Hair Loss | personal data/biological material | monocentric | Prof. R. Hunger |
Dermatology, Bern |
Kantonale Ethikkommission Bern | 11.10.2022 | ||||||||
| 2022-01498 | Antidepressant Withdrawal in primary cARE patients: AWARE | non clinical, involving persons | monocentric | A | PD Dr Michael P Hengartner | Zurich University of Applied Sciences |
Zurich University of Applied Sciences, Zurich |
Kantonale Ethikkommission Zürich | 27.09.2022 | ||||||
| 2022-01496 | Magnetic resonance imaging characteristics in aseptic femoral stem loosening in uncemented total hip arthroplasty | personal data/biological material | monocentric | Dr. Vincent Stadelmann | Schulthess Klinik |
Schulthess Klinik, Zürich |
Kantonale Ethikkommission Zürich | 21.09.2022 | |||||||
| 2022-01495 | Acute and chronic effect of Dapagliflozin on functional renal MRI parameters in non-diabetic patients with chronic kidney disease – the DAPA-BOLD study | clinical trial | drugs | phase 4 | monocentric | A | Dr. med. Laila-Yasmin Mani | Universitätsklinik für Nephrologie und Hypertonie Inselspital |
Universitätsklinik für Nephrologie und Hypertonie Inselspital, Bern |
Kantonale Ethikkommission Bern | 05.01.2023 | ||||
| 2022-01494 | Validating biological age sensors in human fibroblasts | personal data/biological material | monocentric | Sebastian Jessberger | University of Zurich |
University of Zurich, Zurich |
Kantonale Ethikkommission Zürich | 21.09.2022 | |||||||
| 2022-01492 | Sixteen-year mortality and morbidity in preterm infants in Switzerland. | personal data/biological material | monocentric | Porf Riccardo Pfister | University Hospitals of Geneva |
University Hospitals of Geneva, Geneva |
Commission Cantonale d'éthique de la recherche Genève (CCER) | 03.11.2022 | |||||||
| 2022-01491 | Anti-Thrombotic Therapy for Stroke Prevention in Cervical Artery Dissection (STOP-CAD) | personal data/biological material | monocentric | PD Dr. med. Mirjam Heldner |
University hospital Bern, Switzerland |
Kantonale Ethikkommission Bern | 06.09.2022 | ||||||||