| BASEC ID | Project title | Type of project | Type of clinical trial | Study phase (clinical trials only) | multi- / monocentric | Category | Principal investigator | Sponsor | Investigational sites | Lead EC | Local EC(s) | Approval date | Minors | Study Ended | |
|---|---|---|---|---|---|---|---|---|---|---|---|---|---|---|---|
| 2025-02419 | A Phase 3 Study of the Selective Anaplastic Lymphoma Kinase (ALK) Inhibitor NVL-655 Compared to Alectinib in First-Line Treatment of Patients With ALK-Positive Advanced Non-Small Cell Lung Cancer (ALK More ... | clinical trial | drugs | phase 3 | multicentric | C | Dr. Anna Allemann | Nuvalent Inc. |
Luzerner Kantonsspital (LUKS), Luzern EOC - Istituto Oncologico della Svizzera Italiana (IOSI), Via Gallino 12, 6500 Bellinzona |
Ethikkommission Nordwest- und Zentralschweiz EKNZ | Comitato etico cantonale Ticino | 24.02.2026 | |||
| 2025-02418 | Long-term drug adherence and clinical effectiveness of secukinumab in patients with psoriatic arthritis up to 60 months: Results from the EuroSpA collaboration. | personal data/biological material | monocentric | Prof Dr Burkhard Möller | Inselspital - University Hospital Bern |
Inselspital - University Hospital Bern, Bern |
Kantonale Ethikkommission Bern | 13.01.2026 | |||||||
| 2025-02417 | Multicenter Machine Learning-based 1-year Mortality Prediction in Aneurysmal Subarachnoid Hemorrhage (aSAH) | personal data/biological material | monocentric | PD Dr. med. Johannes Goldberg | University Hospital RVVTH Aachen |
Inselspital, Universitätsklinik für Neurochirurgie, Bern |
Kantonale Ethikkommission Bern | 03.02.2026 | |||||||
| 2025-02416 | Retrospective Analysis of Technical Proton Therapy Data at PSI (2014-2025) - REACT study | personal data/biological material | monocentric | Dr. Francesca Albertini | Center for Proton Therapy at Paul Scherrer Institute |
Center for Proton Therapy at Paul Scherrer Institut, Villigen |
Ethikkommission Nordwest- und Zentralschweiz EKNZ | 13.01.2026 | |||||||
| 2025-02415 | The causes and consequences of historical contingencies in the evolution of extensively drug- resistant Mycobacterium tuberculosis | personal data/biological material | monocentric | Professor Sebastien Gagneux |
Swiss Tropical and Public Health institute, Basel |
Ethikkommission Nordwest- und Zentralschweiz EKNZ | 10.12.2025 | ||||||||
| 2025-02413 | Identification of novel autoantibodies in patients with inflammatory demyelinating diseases of the central nervous system | personal data/biological material | monocentric | Prof. Dr. med. Andrew Chan | Inselspital |
Department of Neurology, Inselspital, Bern, Bern |
Kantonale Ethikkommission Bern | 16.03.2026 | |||||||
| 2025-02411 | Persistent incidental FDG-uptake in the prostate as a predictor of prostate cancer | personal data/biological material | monocentric | Dr. med. Hannes Grünig | Luzerner Kantonsspital |
Institut für Radiologie und Nuklearmedizin, Luzern |
Ethikkommission Nordwest- und Zentralschweiz EKNZ | 17.12.2025 | |||||||
| 2025-02407 | Effectiveness of Systemic Perioperative Dexamethasone in Managing Postoperative Pain in Outpatient Hand Surgery | personal data/biological material | monocentric | Médecin adjoint, MERc/Laurent/Wehrli | CHUV |
CHUV, Lausanne |
Commission cantonale d'Éthique de la Recherche sur l'être humain Vaud (CER-VD) | 20.01.2026 | |||||||
| 2025-02406 | Patterns of recurrence in surgically treated high-grade glioma patients in relation to initial tumor stage at primary diagnosis | personal data/biological material | monocentric | Dr. med. Severina Leu | Universitätsspital Basel |
Universitätsspital Basel, Basel |
Ethikkommission Nordwest- und Zentralschweiz EKNZ | 10.12.2025 | |||||||
| 2025-02403 | Utility of Isotopic Red Blood Cell Mass Measurement in the Diagnostic Work-p of Erythrocytosis in 2025 | personal data/biological material | monocentric | Prof Dr Med Lorenzo Alberio | CHUV - Laboratoire |
CHUV, Lausanne |
Commission cantonale d'Éthique de la Recherche sur l'être humain Vaud (CER-VD) | 22.01.2026 | |||||||
| 2025-02399 | Characterisation of Patients Who Received Systemic cancer Therapy Within 30 Days Before Death | personal data/biological material | monocentric | Dr Özdemir Berna |
Inselspital, Bern |
Kantonale Ethikkommission Bern | 27.01.2026 | ||||||||
| 2025-02398 | Evaluation of Side Effects Following Intravesical Onabotulinum Toxin A Injections in Individuals with Spinal Cord Injury or Disease | non clinical, involving persons | monocentric | A | Prof. Dr. med. Jens Wöllner | Schweizer Paraplegiker-Zentrum Nottwil |
Schweizer Paraplegiker-Zentrum, Nottwil |
Ethikkommission Nordwest- und Zentralschweiz EKNZ | 26.01.2026 | ||||||
| 2025-02396 | An emotional-distress-based integrated care programme in patients with stable COPD – A feasibility study (EmoD-2) | clinical trial | other clinical trials | monocentric | A | PhD Christine Hübsch | Unversitätsspital Zürich |
Universitätsspital Zürich, Zürich |
Kantonale Ethikkommission Zürich | 20.02.2026 | |||||
| 2025-02395 | Postoperative MRI evaluation of symptomatic patients after posterior cruciate ligament reconstruction | personal data/biological material | monocentric | Prof. Dr. med. Reto Sutter | Balgrist University Hospital |
Balgrist University Hospital, 8008 Zürich |
Kantonale Ethikkommission Zürich | 18.12.2025 | |||||||
| 2025-02393 | Heimbasierte transkranielle Gleichstromstimulation mittels FLOW- Geräts zur Behandlung von Fatigue bei Personen mit Post-COVID- Syndrom. | clinical trial | other clinical trials | monocentric | A | PD Dr. med. Margret Hund-Georgiadis | REHAB Basel Klinik für Neurorehabilitation und Paraplegiologie |
REHAB Basel, Basel |
Ethikkommission Nordwest- und Zentralschweiz EKNZ | 05.02.2026 | |||||
| 2025-02392 | Bedeutung des Ruheenergieverbrauchs bei Querschnittlähmung: Erkenntnisse für die Erstrehabilitation | personal data/biological material | monocentric | Prof. Dr. Claudio Perret | Swiss Paraplegic Research |
Swiss Paraplegic Research, Nottwil |
Ethikkommission Nordwest- und Zentralschweiz EKNZ | 02.12.2025 | |||||||
| 2025-02391 | The impact of decidual inclusion or sparing in a single unlocked closure of a Cesarean uterine incision: randomized controlled trial | clinical trial | other clinical trials | monocentric | A | PD Dr. Amr Sherif Hamza | Kantonsspital Baden |
Kantonsspital Baden, Baden |
Ethikkommission Nordwest- und Zentralschweiz EKNZ | 25.02.2026 | |||||
| 2025-02389 | A Phase 1 single ascending dose study to evaluate the safety, tolerability, acute effects, and pharmacokinetics of oral ZEN-101 in healthy subjects | clinical trial | drugs | phase 1 | monocentric | C | PD Dr. med. Yasmin Schmid | ZENON Therapeutics AG |
Division of Clinical Pharmacology and Toxicology, University Hospital Basel, 4031 Basel |
Ethikkommission Nordwest- und Zentralschweiz EKNZ | 30.01.2026 | ||||
| 2025-02388 | Neural extracellular vesicles as a liquid biopsy platform for biomarker discovery in pediatric neurological disorders with a severe or progressive phenotype | non clinical, involving persons | monocentric | A | PD Dr. med. Lucia Abela, PhD | University Children's Hospital Zurich |
University Children's Hospital Zurich, Zurich |
Kantonale Ethikkommission Zürich | 14.04.2026 | yes | |||||
| 2025-02387 | Acute subjective effects, physiological effects, and pharmacokinetics of intravenous 5-MeO-DMT infusions in a double-blind, placebo-controlled, single ascending dose study in healthy participants | clinical trial | other clinical trials | monocentric | B | Dr. med. Severin Benjamin Vogt | Universitätsspital Basel |
Universitätsspital Basel, Basel |
Ethikkommission Nordwest- und Zentralschweiz EKNZ | 12.02.2026 | |||||