| BASEC ID | Project title | Type of project | Type of clinical trial | Study phase (clinical trials only) | multi- / monocentric | Category | Principal investigator | Sponsor | Investigational sites | Lead EC | Local EC(s) | Approval date | Minors | Study Ended | |
|---|---|---|---|---|---|---|---|---|---|---|---|---|---|---|---|
| 2021-01835 | SARS-CoV-2 mRNA vaccination in lactating mothers (VLAC) – Characterization of immune responses in serum and breast milk of lactating women | non clinical, involving persons | monocentric | A | Dr Jasmin C Hiestand | EBPI |
EBPI, Zürich |
Kantonale Ethikkommission Zürich | 01.11.2021 | ||||||
| 2021-01834 | A Phase 3 Open-label Rollover Clinical Study of Doravirine/Islatravir (DOR/ISL) Once-daily for the Treatment of HIV-1 Infection in Participants Who Previously Received DOR/ISL in a Phase 2 or Phase 3 More ... | clinical trial | drugs | phase 3 | multicentric | C | PD Dr. med. Dominique Braun | Merck Sharp & Dohme LLC. |
UniversitätsSpital Zürich (USZ), Zürich Inselspital, Universitätsspital Bern, Bern Universitätsspital Basel, Basel Hôpitaux Universitaires de Genève (HUG), Genève Kantonsspital St.Gallen, St.Gallen Os More ... |
Kantonale Ethikkommission Zürich | Ethikkommission Nordwest- und Zentralschweiz EKNZ, Ethikkommission Ostschweiz (EKOS), Kantonale Ethikkommission Bern, Commission Cantonale d'éthique de la recherche Genève (CCER), Comitato etico canto More ... | 09.11.2021 | |||
| 2021-01833 | Ansprechen der Checkpoint-Inhibitor Therapie bei Patienten mit hepato- und cholangiozellulärem Karzinom sowie Analyse unerwünschter immunmediierter Nebenwirkungen | personal data/biological material | monocentric | Prof. Dr. Michael Scharl | Universitätsspital Zürich |
Universitätsspital Zürich, Zürich |
Kantonale Ethikkommission Zürich | 24.09.2021 | |||||||
| 2021-01832 | A Phase 3, Randomized, Double-blind, Placebo-controlled Study to Evaluate Sotatercept When Added to Background Pulmonary Arterial Hypertension (PAH) Therapy in Newly Diagnosed Intermediate- and High-r More ... | clinical trial | drugs | phase 3 | monocentric | C | Prof. Dr. med. Silvia Ulrich | Acceleron Pharma Inc., a wholly-owned subsidiary of Merck & Co., Inc., Rahway, NJ, USA |
Universitätsspital Zürich, Zürich |
Kantonale Ethikkommission Zürich | 15.10.2021 | ||||
| 2021-01831 | AI (artificial intelligence)-based prediction of onset of intracerebral hemorrhage (ICH): Potential and limits | personal data/biological material | monocentric | PD Dr. med. Peter Sporns | Universitätsspital Basel |
Universitätsspital Basel, Radiologie, Basel |
Ethikkommission Nordwest- und Zentralschweiz EKNZ | 14.09.2021 | |||||||
| 2021-01830 | Impact de la raideur de coude sur la performance en course à pied | non clinical, involving persons | monocentric | A | Dr. Frédéric VAUCLAIR | CHUV - Bureau BH/10/238 |
CHUV, Lausanne |
Commission cantonale d'Éthique de la Recherche sur l'être humain Vaud (CER-VD) | 25.11.2021 | ||||||
| 2021-01829 | Reliability and validity study of the measurement procedure for the evaluation of hip abductors strength in an unipodal, standing position - A study protocol | non clinical, involving persons | monocentric | A | Ms Simone Gafner | University of Applied Sciences, Geneva |
University of Applied Sciences, Geneva |
Kantonale Ethikkommission Bern | 21.12.2021 | Study has ended | |||||
| 2021-01828 | Evaluation of a speech test in noise with normal hearing and hearing impaired | non clinical, involving persons | monocentric | A | Prof. Martin Kompis | Inselspital Bern |
Inselspital, Bern |
Kantonale Ethikkommission Bern | 22.11.2021 | Study has ended | |||||
| 2021-01827 | Post Market Clinical Follow Up Study POYA 3.5mm Proximal Tibia System | personal data/biological material | multicentric | Prof. Dr. med Christian Gerber | Bonebridge AG |
University Hospital Balgrist, Zürich Spital Interlaken, Interlaken Spital Nidwalden, Stans Kantonsspital St.Gallen, St.Gallen Department of Orthopaedics, Hopital du Valais, Martigny Kantonsspital Wint More ... |
Kantonale Ethikkommission Zürich | Ethikkommission Nordwest- und Zentralschweiz EKNZ, Ethikkommission Ostschweiz (EKOS), Kantonale Ethikkommission Bern, Kantonale Ethikkommission Zürich, Commission cantonale d'Éthique de la Recherche s More ... | 01.12.2021 | ||||||
| 2021-01826 |
Automatisierte Interpretation von Laborwerten mittels maschinellen Lernens |
personal data/biological material | monocentric | Prof. Stefan Balabanov | privat |
University Hospital Zürich, Zürich |
Kantonale Ethikkommission Zürich | 25.03.2022 | |||||||
| 2021-01825 | TRI0343 – Biomarkers profiling in CSF and plasma samples from human ALS patients | personal data/biological material | monocentric | PhD Magdalena Koziczak-Holbro | Novartis Pharma AG - NIBR |
Novartis Pharma AG, Basel |
Ethikkommission Nordwest- und Zentralschweiz EKNZ | 09.09.2021 | |||||||
| 2021-01824 | Effect of individual nutritional therapy in patients at risk for malnutrition and sarcopenia in pulmonary rehabilitation - a randomized controlled trial | clinical trial | other clinical trials | monocentric | A | Dr. Thimo Marcin | Berner Reha Zentrum AG |
Berner Reha Zentrum, Heiligenschwendi |
Kantonale Ethikkommission Bern | 09.11.2021 | Study has ended | ||||
| 2021-01823 | Validating pErsoNalized 3D-printed Unique breaSt SHELLs for radiotherapy: a proof of concept study | non clinical, involving persons | monocentric | B | Mrs Giovanna Dipasquale | HUG |
HUG, Genève |
Commission Cantonale d'éthique de la recherche Genève (CCER) | 12.10.2021 | Study has ended | |||||
| 2021-01822 | A Phase 3 Randomized Study Comparing Bortezomib, Lenalidomide and Dexamethasone (VRd) followed by Ciltacabtagene Autoleucel, a Chimeric Antigen Receptor T cell (CAR-T) Therapy Directed Against BCMA ve More ... | clinical trial | pathogenic organisms / gmo | multicentric | C | Prof. Dr. Thomas Pabst | Janssen-Cilag International N.V. |
Inselspital, Bern Universitätsspital Basel, Klinik für Hämatologie, Basel Kantonsspital St. Gallen, Onkologie/Hämatologie, St. Gallen |
Kantonale Ethikkommission Bern | Ethikkommission Nordwest- und Zentralschweiz EKNZ, Ethikkommission Ostschweiz (EKOS) | 25.05.2022 | ||||
| 2021-01821 | Using mobile assessments to characterize mental and physical health behaviors in youth (mSanté) | non clinical, involving persons | monocentric | A | Prof / Kerstin /von Plessen | CHUV - SUPEA - Psychiatrie |
SUPEA CHUV, Lausanne |
Commission cantonale d'Éthique de la Recherche sur l'être humain Vaud (CER-VD) | 19.04.2022 | yes | |||||
| 2021-01820 | Understanding the impact of COVID-19 on bacterial sepsis, antibiotic consumption and stewardship, and antimicrobial resistance | personal data/biological material | monocentric | Prof Stephan Harbarth | University of Oxford |
Hôpitaux Universitaires de Genève, Geneva |
Commission Cantonale d'éthique de la recherche Genève (CCER) | 23.11.2021 | |||||||
| 2021-01819 | Gait analysis after fibular (FFF), anterolateral femoral perforator (ALT) and deep circumflex iliac artery perforator free flap (DCIA) harvesting using the Gait-Up device | non clinical, involving persons | monocentric | A | May Laurence | CHUV - Chirurgie orale et maxillo faciale |
CHUV, Lausanne |
Commission cantonale d'Éthique de la Recherche sur l'être humain Vaud (CER-VD) | 26.09.2022 | ||||||
| 2021-01818 | Joint Tissue Collection in Patients with Traumatic and Degenerative Joint Diseases | non clinical, involving persons | monocentric | A | Prof.Dr.med. Oliver Distler | Klinik für Rheumatologie, USZ |
Department of Rheumatology, University Hospital Zurich, Zurich |
Kantonale Ethikkommission Zürich | 26.10.2021 | ||||||
| 2021-01817 | A MULTICENTER, OBSERVATIONAL, 6-MONTH FOLLOW-UP STUDY OF PATIENTS WITH COVID-19 PREVIOUSLY ENROLLED IN A RO7496998 (AT-527) STUDY | non clinical, involving persons | multicentric | A | Prof. Dr. med. Huldrych Günthard | F. Hoffmann La Roche Ltd. |
Universitätsspital Zürich, Klinik für Infektionskrankheiten und Spitalhygiene, Zürich Geneva University Hospital HIV unit - Internal Medicine Department, Geneva |
Kantonale Ethikkommission Zürich | Commission Cantonale d'éthique de la recherche Genève (CCER) | 26.11.2021 | Study has ended | ||||
| 2021-01815 | Aesthetic evaluation of cosmetic results after auricular reconstructive surgery for atresia auris congenita | personal data/biological material | monocentric | Prof. Dr. med. Thomas Linder | Klinik für Hals, Nasen und Ohren |
Klinik für Hals, Nasen und Ohren, Luzerner Kantonsspital, Luzern |
Ethikkommission Nordwest- und Zentralschweiz EKNZ | 29.09.2021 | |||||||