| BASEC ID | Project title | Type of project | Type of clinical trial | Study phase (clinical trials only) | multi- / monocentric | Category | Principal investigator | Sponsor | Investigational sites | Lead EC | Local EC(s) | Approval date | Minors | Study Ended | |
|---|---|---|---|---|---|---|---|---|---|---|---|---|---|---|---|
| 2021-01729 | The effect of physical and psychological stressors on memory | non clinical, involving persons | monocentric | A | Prof. Sophie Schwartz |
Unige, Geneva |
Commission Cantonale d'éthique de la recherche Genève (CCER) | 20.12.2021 | yes | ||||||
| 2021-01728 | Rejection sensitivity, emotion regulation, and mental health among youth (14-24 years) with and without migration background in Switzerland | personal data/biological material | monocentric | Prof. Dr. Eva Heim | University of Lausanne |
Université de Lausanne, Lausanne |
Kantonale Ethikkommission Bern | 21.06.2022 | Study has ended | ||||||
| 2021-01727 | CA224-098: A Phase 3, Randomized, Double-blind Study of Adjuvant Immunotherapy with Nivolumab + Relatlimab Fixed-dose Combination versus Nivolumab Monotherapy after Complete Resection of Stage III-IV More ... | clinical trial | drugs | phase 3 | multicentric | C | Prof. Dr. med. Reinhard Dummer | Bristol-Myers Squibb International Corporation |
UniversitätsSpital Zürich, Zürich Universitätsspital Basel, Basel Kantonsspital Graubünden, Chur |
Kantonale Ethikkommission Zürich | Ethikkommission Nordwest- und Zentralschweiz EKNZ, Kantonale Ethikkommission Zürich | 26.10.2021 | |||
| 2021-01726 | The standard 12-lead ECG for the prediction of size, remodelling, and pressure of the cardiac chambers – established criteria revisited based on echo and cardiac catheterization data. (ECG hypertrophy More ... | personal data/biological material | monocentric | Prof. Dr. Micha Maeder | Kantonsspital St.Gallen |
Kantonsspital St.Gallen, St.Gallen |
Ethikkommission Ostschweiz (EKOS) | 20.08.2021 | Study has ended | ||||||
| 2021-01725 | Description des profils des personnes âgées fragiles de 65 ans et plus hospitalisées dans un hôpital en Suisse romande : une analyse transversale de données longitudinales existantes dans les dossiers More ... | personal data/biological material | monocentric | Professeur Henk Verloo | HES-SO Valais/ Wallis |
Institut Universitaire de Formation de Recherche en Soins, Lausanne |
Commission cantonale d'Éthique de la Recherche sur l'être humain Vaud (CER-VD) | 16.12.2021 | |||||||
| 2021-01724 | Characterization of electroencephalographic (EEG) correlates of natural vision in healthy subjects | non clinical, involving persons | monocentric | A | Prof. Silvestro Micera | EPFL |
EPFL, Institute of Bioengineering, Geneva |
Commission Cantonale d'éthique de la recherche Genève (CCER) | 06.12.2021 | ||||||
| 2021-01723 | A Retrospective Comparison of Patients with Primary and Metastatic Melanoma | personal data/biological material | monocentric | Prof. Dr.Dr. Robert Hunger | Inselspital |
Dermatologie, Inselspital, Bern |
Kantonale Ethikkommission Bern | 13.10.2021 | |||||||
| 2021-01721 | Neuroendocrine Neoplasms Methylation based Classifier - the NEMESIs study | non clinical, involving persons | monocentric | A | Dr. Julie Refardt | University Hospital Basel |
University Hospital Basel, Basel |
Ethikkommission Nordwest- und Zentralschweiz EKNZ | 21.09.2021 | ||||||
| 2021-01720 |
A Phase 3 Open-Label, Randomized Study of Fixed Duration Pirtobrutinib (LOXO-305) plus Venetoclax and Rituximab versus Venetoclax and Rituximab in Previously Treated Chronic Lymphocytic Leukemia/Sma More ... |
clinical trial | drugs | phase 3 | multicentric | C | PD Dr. Davide Rossi | Loxo Oncology Inc |
Istituto Oncologico della Svizzera Italiana (IOSI), Bellinzona Luzerner Kantonsspital, Luzern |
Comitato etico cantonale Ticino | Ethikkommission Nordwest- und Zentralschweiz EKNZ | 10.01.2022 | |||
| 2021-01719 |
PROOF: "Penumbral Rescue by Normobaric O=O Administration in Patients with Ischemic Stroke and Target Mismatch ProFile: A Phase II Proof-of-Concept Trial" |
clinical trial | drugs | phase 2 | multicentric | B | Prof. Patrik Michel | Eberhard-Karls University Tübingen |
Centre Cérébrovasculaire, Service de Neurologie, Lausanne Department of Neurology, Canton Hospital of Aarau, Aarau |
Commission cantonale d'Éthique de la Recherche sur l'être humain Vaud (CER-VD) | Ethikkommission Nordwest- und Zentralschweiz EKNZ | 03.01.2022 | Study has ended | ||
| 2021-01718 | Preventing Oxygen Desaturation during Bronchoscopy using High Flow Oxygen vs Standard management in COPD Patients -PROSA2- | clinical trial | other clinical trials | monocentric | A | Prof. Daiana Stolz | University Hospital Basel |
Universitätsspital Basel, Basel |
Ethikkommission Nordwest- und Zentralschweiz EKNZ | 22.10.2021 | |||||
| 2021-01717 | Therapie-Dosis und Outcome nach Rehabilitation | personal data/biological material | monocentric | Stefan Bachmann | Kliniken Valens |
Kliniken Valens, 7317 Valens |
Ethikkommission Ostschweiz (EKOS) | 20.08.2021 | |||||||
| 2021-01716 | Characteristics and treatment of patients with Precursor B Acute Lymphoblastic Leukemia and Li-Fraumeni Syndrome – a retrospective study. | personal data/biological material | monocentric | PD Dr Med Francesco Ceppi | CHUV - BH11-969 |
CHUV Centre Hospitalier Universitaire Vaudois, Lausanne |
Commission cantonale d'Éthique de la Recherche sur l'être humain Vaud (CER-VD) | 17.09.2021 | |||||||
| 2021-01715 | “Drug survival" des Medikaments Omalizumab in einer Langzeitkohorte von Patienten mit chronisch spontaner Urtikaria (CSU). | personal data/biological material | monocentric | Prof. Dr. med. Peter Schmid-Grendelmeier | Universitätsspital Zürich, Dpt. of Dermatology |
USZ, Zurich |
Kantonale Ethikkommission Zürich | 05.10.2021 | |||||||
| 2021-01714 | Exploring the phenotypic capacity of transcription factors in human embryonic stem cells at the single cell level | personal data/biological material | monocentric | Prof David Suter | EPFL SV IBI-SV |
Ecole Polytechnique Federale de Lausanne, Lausanne |
Commission cantonale d'Éthique de la Recherche sur l'être humain Vaud (CER-VD) | 31.08.2021 | |||||||
| 2021-01713 | Implementation of video-observed therapy (VOT) as a new mode of directly observed therapy (DOT) in the follow-up of treatment for active tuberculosis: a proof of concept study | clinical trial | other clinical trials | monocentric | A | Professor Jean-Paul Janssens | Service de Pneumologie |
Geneva University Hospitals, Genève |
Commission Cantonale d'éthique de la recherche Genève (CCER) | 24.03.2022 | |||||
| 2021-01712 | Evaluating a smartphone-based digital patient portal to facilitate perioperative patient management and determine patient specific outcome measures in spine surgery | personal data/biological material | monocentric | Prof. Dr. med. Mazda Farshad | Universitätsklinik Balgrist |
Universitätsklinik Balgrist, Zürich |
Kantonale Ethikkommission Zürich | 31.08.2021 | |||||||
| 2021-01711 | Thrombocytopenia after aortic valve replacement: a comparison between the sutureless Perceval, the rapid deployment Intuity and the transcatheter Sapien bioprosthesis | personal data/biological material | monocentric | Prof. Dr. med. Dr. h. c. Omer Dzemali |
Stadtspital Triemli Zürich, Zürich |
Kantonale Ethikkommission Zürich | 24.09.2021 | ||||||||
| 2021-01709 | Inflammatory Neuropathy Consortium Base (INCbase). A prospective international CIDP registry. | non clinical, involving persons | multicentric | A | Dr.med. Paolo Ripellino | Neurocenter of Southern Switzerland |
Neurocenter of Southern Switzerland, Lugano Inselspital, Bern Universitaetspital Basel, Basel HUG, Geneva Kantonsspital St. Gallen, St. Gallen HFR Fribourg - Hôpital cantonal, Fribourg CHUV, Lausanne |
Comitato etico cantonale Ticino | Ethikkommission Nordwest- und Zentralschweiz EKNZ, Ethikkommission Ostschweiz (EKOS), Kantonale Ethikkommission Bern, Commission cantonale d'Éthique de la Recherche sur l'être humain Vaud (CER-VD), Co More ... | 31.08.2021 | |||||
| 2021-01708 | A PHASE IV MULTICENTER, OPEN-LABEL STUDY EVALUATING B CELL LEVELS IN INFANTS POTENTIALLY EXPOSED TO OCRELIZUMAB DURING PREGNANCY – THE MINORE STUDY | non clinical, involving persons | multicentric | B | Prof. Dr. med. Tobias Derfuss | F. Hoffmann-La Roche Ltd |
Universitätsspital Basel, Basel Universitätsklinik für Neurologie Inselspital, Bern |
Ethikkommission Nordwest- und Zentralschweiz EKNZ | Kantonale Ethikkommission Bern | 14.12.2021 | yes | ||||