BASEC ID Project title Type of project Type of clinical trial Study phase (clinical trials only) multi- / monocentric Category Principal investigator Sponsor Investigational sites Lead EC Local EC(s) Approval date Minors Study Ended
2024-00248 Identifying risk factors that influence the glomerular filtration rate trajectory in patients with microvascular inflammation in allograft biopsies personal data/biological material monocentric Dr. Matthias Diebold Clinic for Transplantationimmunology and Nephrology, University Hospital Basel University Hospital Basel, Basel Switzerland, Basel
Ethikkommission Nordwest- und Zentralschweiz EKNZ 20.03.2024
2024-00246 CT-guided Lung Biopsy Risk Optimization Method - Effect of Fluid Application in the Pleural Cavity and the Gravitational Effect of Pleural Pressure (BROM-I) clinical trial other clinical trials monocentric B Dr. med. Michael P. Brönnimann Insel Gruppe AG Insel Gruppe AG, Department of Diagnostic, Interventional and Pediatric Radiology, Bern
Kantonale Ethikkommission Bern 15.04.2024
2024-00243 Real-world experience of Faricimab (Vabysmo) treatment for macular pathology in Switzerland personal data/biological material monocentric PD. Dr. med. Martin K. Schmid Luzerner Kantonsspital Augenklinik Luzerner Kantonsspital, Luzern
Ethikkommission Nordwest- und Zentralschweiz EKNZ 14.03.2024
2024-00242 Exploring systemic manifestation of cutaneous T-cell lymphoma non clinical, involving persons monocentric A Dr. med. Dr. sc. med. Egle Ramelyte University Hospital Zürich Universitätsspital Zürich, Zürich
Kantonale Ethikkommission Zürich 17.05.2024
2024-00241 CRISPR-Cas9 screening in colorectal cancer organoids personal data/biological material monocentric Dr. Esposito Roberta Medical Oncology Department, Inselspital Department for BioMedical Research, University of Bern; Medical Oncology, Inselspital, Bern
Kantonale Ethikkommission Bern 18.07.2024
2024-00239 Retrospective analysis of clinical and paraclinical parameters from patients with multiple sclerosis and related disorders personal data/biological material monocentric Prof. Dr. Patrick Roth University Hospital Zurich University Hospital Zurich, Zurich
Kantonale Ethikkommission Zürich 05.07.2024
2024-00238 Inspiratory effort during assisted ventilation: what is normal? personal data/biological material multicentric Francesca Porta Kantonspital Graubünden Kantonspital Graubünden, Chur
Ospedale Civico di Lugano, Lugano
Kantonale Ethikkommission Zürich Comitato etico cantonale Ticino 26.03.2024
2024-00237 The Effect of Acute High Altitude Exposure on Rescuer Performance and Patient Care clinical trial other clinical trials monocentric B Priv.-Doz. Dr. med. Jürgen Knapp Klinik für Anästhesiologie und Schmerztherapie, Universitätsspital Bern Klinik für Anästhesiologie und Schmerztherapie, Universitätsspital Bern, Bern
Kantonale Ethikkommission Bern 08.07.2024
2024-00236 Patient severity based on the NACA Score in Polytrauma: an observational retrospective study personal data/biological material monocentric Prof Dr. med Christian Candrian EOC EOC, Lugano
Comitato etico cantonale Ticino 15.04.2024
2024-00234 CTQJ230A12203 - A randomized double-blind, placebo-controlled, multi-center trial assessing the impact of lipoprotein(a) lowering with pelacarsen (TQJ230) on the progression of calcific aortic valve s More ... clinical trial drugs phase 2 multicentric C Dr. med. Jonathan Michel Novartis Pharma Schweiz Universitätsspital Zürich, Zürich
Universitätsspital Basel, Basel
HUG, Geneve
EOC, Lugano
Kantonale Ethikkommission Zürich Ethikkommission Nordwest- und Zentralschweiz EKNZ, Commission Cantonale d'éthique de la recherche Genève (CCER), Comitato etico cantonale Ticino 19.04.2024
2024-00231 Ticin regIstry for caTheter-based treAtments iN patIents with acute pUlmonary eMbolism non clinical, involving persons monocentric A Prof Marco Valgimigli Cardiocentro Ticino Institute, EOC Cardiocentro Ticino Institute, EOC, Lugano, Lugano
Comitato etico cantonale Ticino 14.05.2024
2024-00230 MK-2870-019: A Phase 3 Randomized Open-Label Study of Adjuvant Pembrolizumab With or Without MK-2870 in Participants With Resectable Stage II to IIIB (N2) NSCLC not Achieving pCR After Receiving Neoad More ... clinical trial drugs phase 3 multicentric C PD Dr. med. Michael Mark Merck Sharp & Dohme LLC Kantonsspital Graubünden, Chur
Spital Thurgau AG, Thurgau
HFR hôpital fribourgeois, Fribourg
Kantonale Ethikkommission Zürich Ethikkommission Ostschweiz (EKOS), Commission cantonale d'Éthique de la Recherche sur l'être humain Vaud (CER-VD) 30.04.2024
2024-00229 Biomechanical Evaluation of Various Refixation Techniques Following Extended Trochanteric Osteotomy and Trochanteric Fractures in a Cadaver Model deceased persons monocentric Prof. Dr. med. Patrick Zingg Universitätsklinik Balgrist Universitätsklinik Balgrist, Zürich
Kantonale Ethikkommission Zürich 12.04.2024
2024-00224 One year results and comparison of two double mobility prostheses for trapeziometacarpal arthritis personal data/biological material monocentric Sebastian Hediger Kantonsspital Frauenfeld Kantonsspital Frauenfeld, Frauenfeld
Ethikkommission Ostschweiz (EKOS) 08.02.2024
2024-00223 Efficacy of Transversus Thoracic Muscle Plane Block in Patients undergoing Cardiac Surgery
A randomized controlled, double blind trial
clinical trial other clinical trials monocentric A PD Dr Sina Grape Hôpital du Valais Service d'Anesthésiologie, Centre Hospitalier du Valais Romand, Sion
Commission cantonale d'Éthique de la Recherche sur l'être humain Vaud (CER-VD) 30.04.2024
2024-00222 Malleostapedotomy: a 20-year updated review of surgical results personal data/biological material monocentric Prof. Dr. med. Thomas Linder HNO LUKS HNO LUKS, Luzern
Ethikkommission Nordwest- und Zentralschweiz EKNZ 27.02.2024
2024-00220 ADE (adverse drug event) Hospitalization – inadäquate Medikation bei geriatrisch hämatologisch-onkologischen Patientinnen und Patienten personal data/biological material monocentric Dr. med. Wiebke Rösler University Hospital Zurich University Hospital Zurich, Zurich
Kantonale Ethikkommission Zürich 25.06.2024
2024-00219 Clinical, radiological and patient related outcomes in Legg-Calvé-Perthès disease. A monocentric case series non clinical, involving persons monocentric A Dre Sophie Merkaert CHUV - DFME - Chirurgie Hôpital de l’enfance, Centre Hospitalier Universitaire Vaudois, Lausanne
Commission cantonale d'Éthique de la Recherche sur l'être humain Vaud (CER-VD) 13.05.2024 yes
2024-00218 Evaluation of the electrical and mechanical properties of the glioblastoma microenvironment and the tumor interactions with existing neural circuits personal data/biological material monocentric Prof. Dr. Dr. G. Hutter NCH Basel NCH Basel, Basel
Ethikkommission Nordwest- und Zentralschweiz EKNZ 14.02.2024
2024-00217 Brachytherapy versus surgery in localized squamous cell carcinoma of the lip: a propensity-matched survival analysis non clinical, involving persons monocentric A PD Dr. med. Olgun Elicin Inselspital Universitätsklinik für Radio-Onkologie, Bern
Kantonale Ethikkommission Bern 03.07.2024