| BASEC ID | Project title | Type of project | Type of clinical trial | Study phase (clinical trials only) | multi- / monocentric | Category | Principal investigator | Sponsor | Investigational sites | Lead EC | Local EC(s) | Approval date | Minors | Study Ended | |
|---|---|---|---|---|---|---|---|---|---|---|---|---|---|---|---|
| 2021-00490 | ACTION: Phase I/II Trial of Abiraterone Acetate in Combination with Tildrakizumab (anti-IL23 targeting monoclonal antibody) in Men with Metastatic Castration-Resistant Prostate Cancer (mCRPC) | clinical trial | drugs | phase 1/2 | monocentric | C | Prof. Andrea Alimonti | The Institute of Cancer Research |
Oncology Institute of Southern Switzerland (IOSI), Bellinzona |
Comitato etico cantonale Ticino | 06.05.2021 | Study has ended | |||
| 2021-00489 |
An observational pilot study to define a liquid biopsy-based fingerprint for Alzheimer's disease (fingerpriAD) |
non clinical, involving persons | monocentric | A | Dr. med. Leonardo Sacco | Tivenix SA |
Istituto di Neuroscienze Cliniche della Svizzera Italiana, Lugano |
Comitato etico cantonale Ticino | 19.04.2021 | Study has ended | |||||
| 2021-00488 | Retrospective monocentric clinical study to assess SI joint screw clinical and radiological performance | personal data/biological material | monocentric | Prof. Dr. med. Clément M.L. Werner | Ortho Clinic Zürich - Klinik im Park |
Ortho Clinic Zürich - Klinik im Park, Zürich |
Kantonale Ethikkommission Zürich | 14.09.2021 | |||||||
| 2021-00487 | Posterolateral Fusion with PEEK (Polyetheretherketone) Rods versus TLIF (Transforaminal Lumbar Interbody Fusion) With Titanium Rods for Single-level Lumbar Spine Degenerative Disease in Patients >70 Y More ... | personal data/biological material | monocentric | Dr. med. Maria Kamenova | Spinale Chirurgie, Universitätsspital Basel |
Unispital Basel, Basel |
Ethikkommission Nordwest- und Zentralschweiz EKNZ | 11.03.2021 | |||||||
| 2021-00486 | Return to Work After Arthroscopic Rotator Cuff Repair | non clinical, involving persons | monocentric | A | Prof Dr.med Christian Candrian | EOC |
EOC, Lugano |
Comitato etico cantonale Ticino | 29.04.2021 | Study has ended | |||||
| 2021-00485 | EMETPRO: Characteristics, treatments and outcomes of metastatic hormone sensitive prostate cancer patients progressing within 6 months of beginning systemic therapy (ADT or ADT with docetaxel or with More ... | personal data/biological material | multicentric | dr. med. Ricardo Pereira Mestre | Oncology Institute of Southern Switzerland (IOSI) |
Istituto Oncologico della Svizzera Italiana (IOSI), Bellinzona Kantonsspital St. Gallen, St. Gallen Kantonsspital Graubünden, Chur |
Comitato etico cantonale Ticino | Ethikkommission Ostschweiz (EKOS), Kantonale Ethikkommission Zürich | 30.03.2021 | ||||||
| 2021-00484 |
A prospective observational study to assess the association between gut microbiome/use of antibiotics and response to treatments for metastatic castration resistant prostate cancer (mCRPC) |
non clinical, involving persons | monocentric | A | Prof. Dr. Med. Andrea Alimonti | Institute of Oncology Research |
Institute of Oncology Research, Bellinzona |
Comitato etico cantonale Ticino | 22.03.2021 | ||||||
| 2021-00483 | Serum Biomarker zur Diagnose einer Neuroborreliose | personal data/biological material | monocentric | Dr. med. Cédric Hirzel | Universitätsklinik für Infektiologie |
Universitätsklinik für Infektiologie, Bern |
Kantonale Ethikkommission Bern | 08.07.2021 | Study has ended | ||||||
| 2021-00482 | Clubfoot recurrence and complications in children managed by Ponseti technique: retrospective analysis of failure rate when single versus multiple providers administered the treatment. | personal data/biological material | monocentric | Dr/Geraldo/De Coulon | Hôpitaux Universitaires de Genève |
Hôpitaux Universitaires de Genève, Geneve |
Commission Cantonale d'éthique de la recherche Genève (CCER) | 18.05.2021 | |||||||
| 2021-00481 | Developing chromatin biomarkers to evaluate tumor state from blood samples of patients undergoing Proton Therapy at PSI | non clinical, involving persons | monocentric | A | Prof.Dr.med. Damien C. Weber | Center for Proton Therapy at Paul Scherrer Institut |
Center for Proton Therapy at Paul Scherrer Institute, Villigen |
Ethikkommission Nordwest- und Zentralschweiz EKNZ | 04.05.2021 | yes | |||||
| 2021-00480 | Neuronal mechanisms underlying the perception and production of speech and communicative signals | non clinical, involving persons | monocentric | A | Dr. Pierre Mégevand | Hôpital Universitaire de Genève |
Hôpital Universitaire de Genève, Genève |
Commission Cantonale d'éthique de la recherche Genève (CCER) | 06.05.2021 | ||||||
| 2021-00479 | Risk factors for failure after surgical therapy in patients with diabetic foot syndrome | personal data/biological material | monocentric | Dr.med. helen Anwander |
Inselspital Bern, Bern |
Kantonale Ethikkommission Bern | 15.04.2021 | ||||||||
| 2021-00477 | Anticoagulants and anti-platelet drugs as an independent risk factor in mild traumatic brain injury: a prospective trial | personal data/biological material | monocentric | Dr. med Laura Uccella | EOC |
EOC Critical Area Department, Lugano |
Comitato etico cantonale Ticino | 29.03.2021 | Study has ended | ||||||
| 2021-00475 | Studio descrittivo retrospettivo e prospettico sull'outcome dei pazienti COVID-19 intubati presso l'Ospedale Regionale di Locarno | personal data/biological material | monocentric | Dr. med. Michele Arigoni | Ospedale Regionale di Locarno |
Ospedale Regionale di Locarno, Locarno |
Comitato etico cantonale Ticino | 25.03.2021 | |||||||
| 2021-00474 | Multiparametric MRI for assessment of changes of renal hemodynamics after fistula closure in kidney transplant patients: a pilot study | non clinical, involving persons | monocentric | A | Prof. Dr. med. Thomas Müller | University Hospital Zurich |
Department of Nephrology, Zürich |
Kantonale Ethikkommission Zürich | 25.05.2021 | ||||||
| 2021-00473 | Multimodal characterizations of central nervous system neoplasms | non clinical, involving persons | monocentric | A | PD Dr. Marian Christoph Neidert | Kantonsspital St.Gallen |
Kantonsspital St.Gallen, St.Gallen |
Ethikkommission Ostschweiz (EKOS) | 29.03.2021 | ||||||
| 2021-00472 | Le ratio neutrophile/lymphocyte mesuré au premier trimestre de la grossesse comme marqueur de détection précoce des fœtus de petit poids pour l'âge gestationnel. | non clinical, involving persons | monocentric | A | Pr Anis Feki | HFR Fribourg-Hôpital Cantonal |
HFR (Hôpital Cantonal de Fribourg), Fribourg |
Commission cantonale d'Éthique de la Recherche sur l'être humain Vaud (CER-VD) | 20.05.2021 | Study has ended | |||||
| 2021-00471 | Structural equation modelling of the interaction between mental state and inflammatory bowel disease | personal data/biological material | monocentric | Prof. Dr. med. Benjamin Misselwitz | Inselspital Bern |
Inselspital - Universitätsklinik für Viszerale Chirurgie und Medizin, Bern |
Kantonale Ethikkommission Bern | 08.06.2021 | |||||||
| 2021-00470 |
Study on feasibility of Targeted Epidural Spinal Stimulation (TESS) to improve mobility in patients with Parkinson’s disease |
clinical trial | medical devices | monocentric | C2 | Prof. Dr. Jocelyne Bloch | CHUV - BH.08.633 |
CHUV, Lausanne |
Commission cantonale d'Éthique de la Recherche sur l'être humain Vaud (CER-VD) | 10.05.2021 | |||||
| 2021-00468 | Immune landscape in breast cancer subtypes, a prospective study | non clinical, involving persons | monocentric | A | Dr. MD Lorenzo Rossi | Oncology Institute of Southern Switzerland (IOSI) |
Oncology Institute of Southern Switzerland (IOSI), Bellinzona |
Comitato etico cantonale Ticino | 29.03.2021 | ||||||