BASEC ID Project title Type of project Type of clinical trial Study phase (clinical trials only) multi- / monocentric Category Principal investigator Sponsor Investigational sites Lead EC Local EC(s) Approval date Minors Study Ended
2023-D0119 A randomized, open-label, multicentric, two-arm pivotal trial of SonoCloud-9 combined with carboplatin (CBDCA) vs standard of care lomustine (CCNU) or temozolomide (TMZ) in patients undergoing planned More ... clinical trial combination drugs/devices multicentric C2 Adjunct Professor Andreas Felix Hottinger CARTHERA Centre Hospitalier Universitaire Vaudois (CHUV), Department of Clinical Neurosciences, Lausanne
Department of Neurosurgery, Bern
Commission cantonale d'Éthique de la Recherche sur l'être humain Vaud (CER-VD) Kantonale Ethikkommission Bern 04.07.2024
2023-D0118 Effect of implant surface material and topography on bone regeneration: A two-centre, parallel-group, pilot study clinical trial medical devices monocentric A1 Dr. med. dent. Anina Zürcher Queen Mary University of London (QMUL) Clinic of Reconstructive Dentistry, Centre of Dental Medicine, University of Zurich, Zurich
Kantonale Ethikkommission Zürich 05.03.2024
2023-D0117 Brain circuitry therapeutics for schizophrenia – A randomized controlled clinical study to treat negative symptoms of schizophrenia using non-invasive stimulation of the cerebellum clinical trial medical devices monocentric C1 Prof. Indrit Bègue University of Geneva University of Geneva, Geneva
Commission Cantonale d'éthique de la recherche Genève (CCER) 15.05.2024
2023-D0116 Protocol-optimization in computed tomography for the quantification of bone mineral density (BMD) clinical trial medical devices monocentric A1 Prof. Dr. med. Hatem Alkadhi Diagnostic and Interventional Radiology University Hospital Zurich Diagnostic and Interventional Radiology University Hospital Zurich, Zurich
Kantonale Ethikkommission Zürich 23.01.2024
2023-D0113 PEERLESS II - Randomized Controlled Trial of FlowTriever vs. Anticoagulation alone in Pulmonary Embolism clinical trial medical devices multicentric A1 Dr. Gregor Leibundgut Inari Medical Europe GmbH Universitätsspital Basel, Basel
Inselspital Bern, Bern
Luzerner Kantonsspital, Spitalstrasse
Ethikkommission Nordwest- und Zentralschweiz EKNZ Kantonale Ethikkommission Bern, Ethikkommission Nordwest- und Zentralschweiz EKNZ 25.01.2024
2023-D0112 Internet-Based Treatment for Depression: A Randomized Trial Comparing Therapist Support and Peer-Support Using an Online Forum. clinical trial medical devices monocentric A1 Prof. Dr. Chantal Martin-Soelch University of Fribourg University of Fribourg, Fribourg
Commission cantonale d'Éthique de la Recherche sur l'être humain Vaud (CER-VD) 27.05.2024
2023-D0111 A novel endoscopic attachment cap for benign esophageal stricture dilation in children: a randomized, multicentric pilot study. clinical trial medical devices multicentric A1 Dr. med. Vasiliki Spyropoulou University Children’s Hospital Zurich University Children’s Hospital, Zurich
Universitäts-Kinderspital beider Basel, Spitalstrasse 33, 4056 Basel, Switzerland
Kantonale Ethikkommission Zürich Ethikkommission Nordwest- und Zentralschweiz EKNZ 19.03.2024 yes
2023-D0110 Brain aging – a comparative study in healthy and patients with Multiple Sclerosis as model of a chronic neuroinflammatory disorder clinical trial medical devices monocentric C2 PD Dr. med Robert Hoepner Inselgruppe AG Inselgruppe AG, Bern
Kantonale Ethikkommission Bern 07.03.2024
2023-D0109 Evaluation of the safety and efficacy of the reSept ASD Occluder to treat patients with clinically significant secundum atrial septal defect (ASCENT ASD Study) clinical trial medical devices multicentric C2 Prof Dr med Oliver Kretschmar atHeart Medical LLC KISPI, Zurich
CHUV, Rue de Bugnon 21
Kantonale Ethikkommission Zürich Commission cantonale d'Éthique de la Recherche sur l'être humain Vaud (CER-VD) 28.05.2024 yes
2023-D0108 PREPICare: Assessment of an Innovative Air Mattress on Critically Ill Infants clinical trial medical devices monocentric C2 Prof. Dr. med. Barbara Brotschi Audenblatten Empa Universitätskinderspital Zürich, Zürich
Kantonale Ethikkommission Zürich 19.03.2024 yes
2023-D0107 A Non-Randomized, Prospective or Retrospective, Open-Label, Multi-Center, Observational Clinical Study with Two Arms to Further Evaluate Safety and Performance of the NEXUS® Aortic Arch Stent Graft Sy More ... clinical trial medical devices monocentric A1 Prof. Dr. med. Mario Lachat Endospan ltd Hirslanden Klinik, Zürich
Kantonale Ethikkommission Zürich 12.12.2023
2023-D0106 Exploratory study of NeuroLF, an investigational medical device without CE-marking for PET imaging of the human brain clinical trial medical devices monocentric C2 Prof. Dr. Martin Hüllner Positrigo AG University Hospital Zurich, Zurich
Kantonale Ethikkommission Zürich 14.05.2024
2023-D0105 A mobile application as supportive treatment of endometriosis: the effect on quality of life and endometriosis-associated pain. A randomized controlled trial. clinical trial medical devices monocentric A1 Dr. med. Marietta Gulz University Hospital of Obstetrics and Gynaecology University Hospital of Bern Department of Gynecology and Obstetrics, Bern
Kantonale Ethikkommission Bern 20.12.2023
2023-D0103 Safety and performance of the Biphasic Plate Distal Femur: A multicenter case series clinical trial medical devices multicentric A1 Dr.Med Christian Michelitsch 41medical AG Kantonsspital Graubunden, Chur
University Hospital Basel, Department of Orthopaedics and Traumatology
Unive
Universitätsspital Zürich, Rämistrasse 100
Kantonale Ethikkommission Zürich Kantonale Ethikkommission Zürich, Ethikkommission Nordwest- und Zentralschweiz EKNZ 23.01.2024
2023-D0102 Brain Controlled Spinal Cord Stimulation in Participants with Spinal Cord Injury for Lower Limb Rehabilitation clinical trial medical devices monocentric C2 Prof. Dr. Jocelyne Bloch EPFL SV BMI UPCOURTINE CHUV, Lausanne
Commission cantonale d'Éthique de la Recherche sur l'être humain Vaud (CER-VD) 14.03.2024
2023-D0101 A multicentric, prospective clinical investigation to evaluate microwave imaging via MammoWave® in a population-based screening program for early breast cancer detection to make breast cancer screeni More ... clinical trial medical devices monocentric C2 Prof. Thomas Frauenfelder Umbria Bioenergeenering Technologies (UBT) srl University Hospital Zurich, Zurich
Kantonale Ethikkommission Zürich 07.06.2024
2023-D0100 Overnight Treatment of Parkinson's Disease Using Vestibular Stimulation from a Rocking Bed (Somnomat Casa) – A Feasibility Study clinical trial medical devices monocentric C2 Dr. med. Lenard Lachenmayer Inselspital, Universitätsspital Bern Inselspital, University Hospital, Bern
Kantonale Ethikkommission Bern 11.01.2024
2023-D0097 CAMBRIA-2 (ClinO-MD)
A Phase III, Open-Label, Randomised Study to Assess the Efficacy and Safety of Camizestrant (AZD9833, a Next-Generation, Oral Selective Estrogen Receptor Degrader) Versus Standar More ...
clinical trial in vitro diagnostic medical devices multicentric C2 Dr. med. Ursina Zürrer-Härdi AstraZeneca AB Kantonsspital Winterthur, Klinik für Medizinische Onkologie und Hämatologie, Winterthur
Kantonsspital Baden, Im Ergel
Hirslandenklinik St. Anna, Zentrum für Onkologie
St. Anna-Strasse 32
Universitäts More ...
Kantonale Ethikkommission Zürich Commission cantonale d'Éthique de la Recherche sur l'être humain Vaud (CER-VD), Ethikkommission Ostschweiz (EKOS), Kantonale Ethikkommission Zürich, Ethikkommission Nordwest- und Zentralschweiz EKNZ, More ... 28.03.2024
2023-D0096 BIO|MASTER.Amvia
Post Market Clinical Follow-up Study for the Amvia/Solvia Pacemaker Family
clinical trial medical devices monocentric A1 Dr. Christian Grebmer BIOTRONIK SE & Co. KG Luzerner Kantonsspital, Luzern
Ethikkommission Nordwest- und Zentralschweiz EKNZ 21.11.2023
2023-D0094 A Single-Arm Pilot Study to Evaluate the Safety of Adipearl Injection in the Subcutanaeous Tissues of Adults clinical trial medical devices monocentric C2 Dr. Johann Wary Volumina Medical S.A. Summit Clinic, Crans-Montana
Commission cantonale d'Éthique de la Recherche sur l'être humain Vaud (CER-VD) 19.01.2024