BASEC ID Project title Type of project Type of clinical trial Study phase (clinical trials only) multi- / monocentric Category Principal investigator Sponsor Investigational sites Lead EC Local EC(s) Approval date Minors Study Ended
2023-01734 Anterior Longitudinal Ligament (ALL) reconstruction improves biomechanical stability and controlled range of motion after cervical fusion or disc arthroplasty deceased persons monocentric Prof. Dr. med. Mazda Farshad Universitätsklinik Balgrist Universitätsklinik Balgrist, Zürich
Kantonale Ethikkommission Zürich 17.11.2023
2023-01732 Interreader-Variabilität in der Beurteilung von Kalziumablagerungen der Koronararterien mittels Low-dose-Computertomographie personal data/biological material monocentric PD Dr. med. Tobias Gassenmaier Luzerner Kantontsspital, Luzern
Ethikkommission Nordwest- und Zentralschweiz EKNZ 21.09.2023
2023-01731 TYK2 inhibition in paradoxical psoriasis (TYPP)
A randomized, double-blind, placebo-controlled multi-center study evaluating the effect of Deucravacitinib on severity of psoriasis in patients with pa More ...
clinical trial drugs phase 2 monocentric C Prof Curdin Conrad Dermatologie CHUV Dermatologie CHUV, Lausanne
Commission cantonale d'Éthique de la Recherche sur l'être humain Vaud (CER-VD) 11.04.2024
2023-01730 iCHECK: Impact of clonal haematopoiesis on the efficacy of checkpoint inhibition: A retrospective single center analysis. personal data/biological material monocentric Dr. med. Dr. sc. nat. Jeremy Deuel Universitätsspital Zürich Universitätsspital, Zürich
Kantonale Ethikkommission Zürich 19.12.2023
2023-01727 International Real-World Study of MET Overexpression in Patients with Non-Small Cell Lung Cancer (METRIX study) personal data/biological material monocentric PD Dr. med. Spasenija Savic Prince AbbVie AG Universitätsspital Basel, Basel
Ethikkommission Nordwest- und Zentralschweiz EKNZ 24.10.2023
2023-01726 COMPANION DIAGNOSTICS: Measurement of the GSM Phase 1 trial (BP44161) with CSF and blood based biomarker immunoassays - RD006619 personal data/biological material monocentric Ms Geraldine Peeters Roche Diagnostics GmbH Labcorp, Meyrin
Commission Cantonale d'éthique de la recherche Genève (CCER) 09.10.2023
2023-01724 Subsartorial Saphenous Nerve Block (SSNB) versus Femoral Nerve Block (FNB) in primary Total Knee Arthroplasty (TKA) combined with Infiltration between Popliteal Artery and Capsule of the Knee (IPACK) More ... clinical trial other clinical trials monocentric A Dr. med. Judith Bering Klinik für Orthopädie und Unfallchirurgie Klinik für Orthopädie und Unfallchirurgie Luzerner Kantonsspital, Luzern
Ethikkommission Nordwest- und Zentralschweiz EKNZ 25.10.2023
2023-01723 Gibt es einen Zusammenhang zwischen der Dosis, Wirksamkeit, Toxizität und fettfreien Körpermasse von Krebspatienten, die mit Tyrosinkinaseinhibitoren behandelt werden? personal data/biological material monocentric Dr Berna Özdemir Inselspital Inselspital, Bern
Kantonale Ethikkommission Bern 24.10.2023
2023-01721 AMBRA: Assessment of Microstructural Brain Alterations
Assessment of myelin content and tissue microstructure in multiple sclerosis: a repeated MRI study
non clinical, involving persons monocentric B Prof.Dr.med.Dr.phil. Cristina Granziera Research Center for Clinical Neuroimmunology and Neuroscience RC2NB University Hospital Basel, Basel
Ethikkommission Nordwest- und Zentralschweiz EKNZ 12.12.2023
2023-01719 Bland portal vein thrombosis in patients with hepatocellular carcinoma: characteristics, clinical features and response to anticoagulation personal data/biological material monocentric Prof. Annalisa Berzigotti Insel Gruppe AG Insel Gruppe AG, Bern
Kantonale Ethikkommission Bern 10.11.2023
2023-01718 Physiological activation measured by EEG during physical effort non clinical, involving persons monocentric A Petra Susan Hüppi Hôpitaux Universitaires de Genève University of Geneva, Geneva
Commission Cantonale d'éthique de la recherche Genève (CCER) 11.12.2023 yes
2023-01717 M23-698: A Phase 3, Randomized, Placebo-Controlled, Double-Blind Study to Evaluate Efficacy and Safety of Upadacitinib in Adult and Adolescent Subjects with Moderate to Severe Hidradenitis Suppurativa More ... clinical trial drugs phase 3 multicentric C Prof. Dr. med. Reinhard Dummer AbbVie Inc. USZ, Dermatologische Klinik, Zürich
Universitätsklinik für Dermatologie, Insel Bern, Bern
HUG,Dermatologie et Vénéréologie, Genève
KSSG, Klinik für Dermatologie, St.Gallen
Kantonale Ethikkommission Zürich Ethikkommission Ostschweiz (EKOS), Kantonale Ethikkommission Bern, Commission Cantonale d'éthique de la recherche Genève (CCER) 12.12.2023 yes
2023-01716 Effects of Intravenous [Pyr1]apelin-13 in Healthy Volunteers with Artificially Induced SIAD and Patients with SIAD – a monocentric randomized double-blind placebo-controlled cross-over study - the esc More ... clinical trial other clinical trials monocentric B Prof. Dr. med. Mirjam Christ-Crain Universitätsspital Basel Universitätsspital Basel, Basel
Ethikkommission Nordwest- und Zentralschweiz EKNZ 14.11.2023
2023-01715 Effect of Glucagon-like peptide-1 receptor agonists (GLP-1 RA) on alcohol consumption, metabolism and liver parameters in patients with obesity and fatty liver disease clinical trial drugs n/a monocentric A Dr. med. Sussana Gomes Rodrigues Insel Gruppe AG Insel Gruppe AG, Bern
Kantonale Ethikkommission Bern 11.01.2024
2023-01714 Sex disparities in infections after solid organ transplantation – A Swiss Transplant Cohort Study Registry Study personal data/biological material monocentric PD Dr Dr Vanessa Banz Universitätsklinik für Viszerale Chirurgie und Medizin Inselspital, Universitätsspital Bern, Bern
Kantonale Ethikkommission Bern 18.10.2023
2023-01713 Mécanismes moléculaires de la toxicité de la protéinurie lors de l'insuffisance rénale chronique personal data/biological material monocentric Prof. Sophie de Seigneux Geneva University Hospitals, Geneva
Commission Cantonale d'éthique de la recherche Genève (CCER) 19.03.2024
2023-01712 Longitudinale Analyse von Behandlungsergebnissen beim NSCLC im Stadium III personal data/biological material monocentric PD Dr. Tobias Finazzi Universitätsspital Basel Universitätsspital Basel, Basel
Ethikkommission Nordwest- und Zentralschweiz EKNZ 14.12.2023
2023-01711 CLNP023B12001B - An open-label, non-randomized extension study to evaluate the long-term efficacy, safety and tolerability of LNP023 in subjects with C3 glomerulopathy clinical trial drugs phase 3 monocentric C Prof. Dr. med. Uyen Huynh-Do Novartis Pharma Schweiz AG Inselspital, Bern
Kantonale Ethikkommission Bern 06.12.2023
2023-01710 Prospective validation of the EBJIS Definition of Periprosthetic Joint Infection personal data/biological material monocentric PD Dr. med UMC Groningen Martin, Clauss
Ethikkommission Nordwest- und Zentralschweiz EKNZ 26.09.2023
2023-01707 Einflussfaktoren auf das Delayed Gastric Emptying und die
Lebensqualität nach partieller Duodenopankreatektomie
personal data/biological material monocentric PD Dr. Ignazio Tarantino Kantonsspital St. Gallen Kantonsspital St. Gallen, St. Gallen
Ethikkommission Ostschweiz (EKOS) 14.09.2023