| BASEC ID | Project title | Type of project | Type of clinical trial | Study phase (clinical trials only) | multi- / monocentric | Category | Principal investigator | Sponsor | Investigational sites | Lead EC | Local EC(s) | Approval date | Minors | Study Ended | |
|---|---|---|---|---|---|---|---|---|---|---|---|---|---|---|---|
| 2020-02394 | EFC16295 - A Phase 3 open-label, multicenter study of the safety, efficacy and pharmacokinetics of intravenous recombinant coagulation Factor VIII Fc-von Willebrand Factor-XTEN fusion protein (rFVIIIF More ... | clinical trial | drugs | phase 3 | monocentric | C | Prof. Dr. med. Manuela Albisetti Pedroni | Bioverativ Therapeutics Inc. (a Sanofi Company) |
Universitäts-Kinderspital Zürich – Eleonorenstiftung, Zürich |
Kantonale Ethikkommission Zürich | 24.11.2020 | yes | Study has ended | ||
| 2020-02393 | GR41987 A MULTICENTER, OPEN-LABEL EXTENSION STUDY TO EVALUATE THE LONG-TERM SAFETY AND TOLERABILITY OF FARICIMAB IN PATIENTS WITH DIABETIC MACULAR EDEMA | clinical trial | drugs | phase 3 | monocentric | C | Dr. Katja Hatz | Roche Pharma (Schweiz) AG |
Vistaklinik, Binningen |
Ethikkommission Nordwest- und Zentralschweiz EKNZ | 26.11.2020 | Study has ended | |||
| 2020-02392 | Motor and non-motor outcomes of deep brain stimulation | personal data/biological material | monocentric | Prof Paul Krack | Inselspital Bern |
Inselspital, Bern |
Kantonale Ethikkommission Bern | 27.07.2021 | |||||||
| 2020-02391 | A Phase III, Multicenter, Randomized, Parallel Group, Double Blind, Double Dummy, Active Controlled Study of Evobrutinib Compared with Teriflunomide, in Participants with Relapsing Multiple Sclerosis More ... | clinical trial | drugs | phase 3 | multicentric | C | Prof. Dr. med. Chiara Zecca | Merck Healthcare KGaA |
Ospedale Regionale di Lugano, Lugano Inselspital, Universitätspital Bern, Bern Kantonsspital Aarau, Aarau |
Comitato etico cantonale Ticino | Ethikkommission Nordwest- und Zentralschweiz EKNZ, Kantonale Ethikkommission Bern | 19.01.2021 | Study has ended | ||
| 2020-02390 | Cardiac function in patients with Duchenne Muscular Dystrophy treated with Tamoxifen compared to Placebo | personal data/biological material | monocentric | Prof. Dr. med. Dirk Fischer |
Universitätskinderspital beider Basel (UKBB), Basel |
Ethikkommission Nordwest- und Zentralschweiz EKNZ | 19.10.2020 | ||||||||
| 2020-02389 | Postoperative complications at the Luzerner Kantonsspital | personal data/biological material | monocentric | PD Dr. med. Christian Fankhauser | Luzerner Kantonsspital, Klinik für Urologie |
Luzerner Kantosspital, Luzern |
Ethikkommission Nordwest- und Zentralschweiz EKNZ | 26.11.2020 | |||||||
| 2020-02388 | Feasibility of technology-based cognitive-motor training in rehabilitation: A pilot-trial | clinical trial | other clinical trials | multicentric | A | Prof. Eling D. de Bruin | ETH Zurich |
ETH Zurich, Zurich Rehaklinik Zihlschlacht, Zihlschlacht Rehaklinik Dussnang, Dussnang Rehaklinik Seewis, Seewis |
Kantonale Ethikkommission Zürich | Ethikkommission Ostschweiz (EKOS), Kantonale Ethikkommission Zürich | 01.12.2020 | ||||
| 2020-02387 | Impact of gut microbiota and immune contexture on effectiveness of neo-adjuvant chemo-radiotherapy in locally advanced rectal cancer | personal data/biological material | multicentric | Prof. Dr. med. D. Christoforidis | EOC |
EOC Surgical Department, Lugano Unità di ricerca clinica/Servizio di Radioterapia Clinica Luganese Moncucco, Lugano |
Comitato etico cantonale Ticino | Comitato etico cantonale Ticino | 09.11.2020 | ||||||
| 2020-02386 | The Lugano classification for diverticulitis | non clinical, involving persons | monocentric | A | Prof. Dr.med | EOC Surgery Department |
EOC Surgery Department, Lugano |
Comitato etico cantonale Ticino | 29.10.2020 | Study has ended | |||||
| 2020-02385 | A Phase 3 Randomized, Double-blind, Multicenter, Global Study of Monalizumab or Placebo in Combination With Cetuximab in Participants With Recurrent or Metastatic Squamous Cell Carcinoma of the Head a More ... | clinical trial | drugs | phase 3 | multicentric | C | Dr. Petr Szturz | AstraZeneca AB |
CHUV, Centre hospitalier universitaire vaudois, Lausanne Inselspital Bern, Universitätsklinik für Medizinische Onkologie, Bern Universitätsspital Basel - Klinik für Onkologie, Basel |
Commission cantonale d'Éthique de la Recherche sur l'être humain Vaud (CER-VD) | Ethikkommission Nordwest- und Zentralschweiz EKNZ, Kantonale Ethikkommission Bern | 09.03.2021 | Study has ended | ||
| 2020-02384 | Transcantonal early detection and intervention in adolescents and young adults with high psychosis risk (PsyYoung) | non clinical, involving persons | multicentric | A | Christian Huber | CHUV |
UPK Basel, Basel Unité de psychiatrie du jeune adulte / HUG, Geneva Service de Psychiatrie générale-DP/CHUV, Lausanne |
Ethikkommission Nordwest- und Zentralschweiz EKNZ | Commission cantonale d'Éthique de la Recherche sur l'être humain Vaud (CER-VD), Commission Cantonale d'éthique de la recherche Genève (CCER) | 08.02.2021 | yes | ||||
| 2020-02383 | Characterization of intestinal microbiota in children with inborn errors of metabolism (IEM) | non clinical, involving persons | monocentric | A | Prof. Dr. med. Johannes Häberle | ETH Zürich |
Universitäts-Kinderspital, Zürich |
Kantonale Ethikkommission Zürich | 17.11.2020 | yes | Study has ended | ||||
| 2020-02381 | Suivi clinique rétrospectif et prospectif des patients ayant bénéficié d’une fermeture percutanée de l’appendice auriculaire gauche | non clinical, involving persons | monocentric | A | Dr Stéphane Noble | Service de Cardiologie |
Hôpitaux universitaires de Genève, Genève |
Commission Cantonale d'éthique de la recherche Genève (CCER) | 09.02.2021 | ||||||
| 2020-02380 | Prevalence of enterococcal groin colonization in cardiological patients | personal data/biological material | monocentric | PD Dr. med., MSc, Anna Conen | Kantonsspital Aarau |
Kantonsspital Aarau, Aarau |
Ethikkommission Nordwest- und Zentralschweiz EKNZ | 23.10.2020 | Study has ended | ||||||
| 2020-02379 | Validation de la stabilité inter-rater et intra-rater du codage du diagnostic des troubles cognitifs selon les critères de la Banque Nationale Alzheimer dans le Centre Leenaards de la Mémoire du CHUV. | personal data/biological material | monocentric | Prof.Jean-françois Démonet | Centre Leenaards de la mémoire |
Centre Leenaards de la mémoire, Lausanne |
Commission cantonale d'Éthique de la Recherche sur l'être humain Vaud (CER-VD) | 24.11.2020 | |||||||
| 2020-02378 | Evaluation of the efficacy of Methylene Blue administration in SARS-CoV2- affected patients: a phase 2, randomized, placebo- controlled, single blind clinical trial | clinical trial | drugs | phase 2 | monocentric | C | Prof Dr Med Andreas Cerny | Epatocentro Ticino |
Epatocentro Ticino, Lugano |
Comitato etico cantonale Ticino | 05.11.2020 | Study has ended | |||
| 2020-02377 | Evaluation of Arm-level Alterations in Individual Cancer Patients | personal data/biological material | monocentric | Dr Petros Tsantoulis | Hôpitaux Universitaire de Genève |
Hôpitaux Universitaire de Genève, Genève |
Commission Cantonale d'éthique de la recherche Genève (CCER) | 21.12.2020 | Study has ended | ||||||
| 2020-02376 | 19225 ASSESS-CKD: A randomized, double-blind, placebo-controlled, multi-center study to assess the efficacy and safety of BAY 2327949 in patients with chronic kidney disease (eGFR range from 25 to 60 More ... | clinical trial | drugs | phase 2 | multicentric | C | PD Dr. med. Stefan Bilz | Bayer (Schweiz) AG |
Kantonsspital St. Gallen, St. Gallen Inselspital Bern, Bern Centre Hospitalier Universitaire Vaudois (CHUV), Lausanne |
Ethikkommission Ostschweiz (EKOS) | Kantonale Ethikkommission Bern, Commission cantonale d'Éthique de la Recherche sur l'être humain Vaud (CER-VD) | 23.11.2020 | Study has ended | ||
| 2020-02375 | Phenotypic and molecular characterization of leukocytes in human bladder cancer | non clinical, involving persons | monocentric | A | Dr Petros Tsantoulis | Université de genève |
Hôpitaux universitaire de Genève, Genève |
Commission Cantonale d'éthique de la recherche Genève (CCER) | 14.12.2020 | ||||||
| 2020-02373 | Neural correlates of heartbeat and auditory processing in awake and sleeping individuals | non clinical, involving persons | multicentric | A | Dr Marzia De Lucia | CHUV - EEG platform - LREN |
Lausanne University Hospital, Lausanne Université de Genève, Genève |
Commission cantonale d'Éthique de la Recherche sur l'être humain Vaud (CER-VD) | Commission Cantonale d'éthique de la recherche Genève (CCER) | 25.11.2020 | |||||