| BASEC ID | Project title | Type of project | Type of clinical trial | Study phase (clinical trials only) | multi- / monocentric | Category | Principal investigator | Sponsor | Investigational sites | Lead EC | Local EC(s) | Approval date | Minors | Study Ended | |
|---|---|---|---|---|---|---|---|---|---|---|---|---|---|---|---|
| 2020-02372 | Etude Companion Diagnostic: “ D159559; Performance of VENTANA PD-L1 (SP263) CDx Assay with OptiView DAB IHC Detection on the BenchMark ULTRA Instrument for Determining the PD-L1 Expression Level of N More ... | personal data/biological material | monocentric | Dr Paul Mesange | Covance CLS |
Covance CLS, Geneva |
Commission Cantonale d'éthique de la recherche Genève (CCER) | 06.10.2020 | Study has ended | ||||||
| 2020-02371 | Efficacité technique et clinique dans le cadre de la prise en charge endoscopique de la pancréatite chronique calcifiante et de ses complications. | personal data/biological material | monocentric | Dr Sébastien Godat | CHUV-Gastro-entérologie |
CHUV, Lausanne |
Commission cantonale d'Éthique de la Recherche sur l'être humain Vaud (CER-VD) | 16.02.2021 | |||||||
| 2020-02370 | Uncovering the Neural Representation of Epistemic Curiosity. | non clinical, involving persons | monocentric | A | David Sander | Swiss Center for Affective Sciences |
Swiss Center for Affective Sciences, Geneva, Switzerland |
Commission Cantonale d'éthique de la recherche Genève (CCER) | 29.09.2021 | ||||||
| 2020-02369 | Follow-up Assessment of Rhinitis - Quality of Life in Allergic Patients Treated with Intralymphatic Immunotherapy (ILIT) | non clinical, involving persons | monocentric | A | Professor Pål Johansen, PhD | University Hospital Zurich & University of Zurich |
University Hospital Zurich & University of Zurich, Zurich |
Kantonale Ethikkommission Zürich | 19.01.2021 | Study has ended | |||||
| 2020-02368 | Usage of the validated German Sino Nasal Outcome Test- 22 (SNOT-22) in clinics | non clinical, involving persons | monocentric | A | Dr Marlene Speth |
HNO, Kantonsspital Aarau, Aarau |
Ethikkommission Nordwest- und Zentralschweiz EKNZ | 11.11.2020 | |||||||
| 2020-02367 |
Development and external validation of an international, multicenter machine learning algorithm for prediction of anastomotic insufficiency after colonic or colorectal anastomosis. The Prediction of More ... |
personal data/biological material | multicentric | Dr. med. Anas Taha | Kantonsspital Winterthur |
Kantonsspital Winterthur, Winterthur Clarunis, Universitäres Bauchzentrum, 4031 Basel Geneva University Hospitals; Department of Surgery, 1211 Geneva 14 Kantonsspital St.Gallen; Klinik für Allgemein-, More ... |
Kantonale Ethikkommission Zürich | Ethikkommission Nordwest- und Zentralschweiz EKNZ, Ethikkommission Ostschweiz (EKOS), Commission Cantonale d'éthique de la recherche Genève (CCER) | 19.01.2021 | Study has ended | |||||
| 2020-02366 | Comparaison des risques de complications maternelles et néonatales après induction du travail par ballonnet simple versus par prostaglandines au CHUV : une étude rétrospective | personal data/biological material | monocentric | David Desseauve | CHUV - DFME |
CHUV, Lausanne |
Commission cantonale d'Éthique de la Recherche sur l'être humain Vaud (CER-VD) | 03.02.2021 | |||||||
| 2020-02365 | Upadacitinib treatment patterns, achievement of treatment targets, sleep evaluation and maintenance of response in moderate to severe Rheumatoid Arthritis patients in real-world practice (UPHOLD-SLEER More ... | non clinical, involving persons | multicentric | A | Prof. Dr. Andrea Rubbert-Roth | AbbVie AG |
KSSG, Klinik für Rheumatologie, St. Gallen Inselspital, Universitätsklinik für Rheumatologie, Immunologie und Allergologie, Bern Universitaetsspital Basel, Rheumatologie, Basel Kantonsspital Aarau, Rh More ... |
Ethikkommission Ostschweiz (EKOS) | Ethikkommission Nordwest- und Zentralschweiz EKNZ, Ethikkommission Ostschweiz (EKOS), Kantonale Ethikkommission Bern, Commission cantonale d'Éthique de la Recherche sur l'être humain Vaud (CER-VD) | 21.12.2020 | |||||
| 2020-02364 | Investigation of tumor kinetics, immune-related adverse events, serum biomarkers and clinicopathological risk factors in melanoma patients receiving systemic therapy. | personal data/biological material | monocentric | Dr. Nikolaus Wagner | Kantonsspital St. Gallen |
Kantonsspital St. Gallen, Klinik für Dermatologie, St. Gallen |
Ethikkommission Ostschweiz (EKOS) | 01.10.2020 | |||||||
| 2020-02363 | A PROSPECTIVE COMPARATIVE MONOCENTRIC RESEARCH PROJECT TO COMPARE CORTICAL BONE TRAJECTORY SCREW INSERTION TECHNIQUE WITH PEDICLE SCREW INSERTION TECHNIQUE BY USE OF PATIENT SPECIFIC DRILL GUIDES | personal data/biological material | monocentric | PD Dr. med François Porchet | Medacta International SA |
Schulthess Klinik, Zurich |
Kantonale Ethikkommission Zürich | 27.10.2020 | |||||||
| 2020-02361 | Joint line orientation after total knee arthroplasty does not affect joint awareness measured with the Forgotten Joint Score-12 | personal data/biological material | monocentric | MD Henrik Behrend | Dep of Orthopaedic Surgery, KSSG |
KSSG, St. Gallen |
Ethikkommission Ostschweiz (EKOS) | 19.11.2020 | |||||||
| 2020-02360 |
A Phase 3b Open-label Study Evaluating the Long-term Safety and Efficacy of Elexacaftor/Tezacaftor/Ivacaftor Combination Therapy in Cystic Fibrosis Subjects Ages 6 Years and Older Who Are Heterozygou More ... |
clinical trial | drugs | phase 3 | multicentric | C | Prof. Dr. med. Alexander Möller | Vertex Pharmaceuticals (Germany) GmbH |
Universitätskinderspital Zürich, Zürich Inselspital-Universitätsspital Bern, Bern |
Kantonale Ethikkommission Zürich | Kantonale Ethikkommission Bern | 01.12.2020 | yes | Study has ended | |
| 2020-02358 | Retinal imaging at a cellular level: Exploring retinal cellular topology and microvascular architecture in retinal diseases with a novel non-invasive retinal imaging camera | non clinical, involving persons | monocentric | A | Professor Thomas Wolfensberger | Hôpital ophtalmique Jules-Gonin |
Jules-Gonin Eye Hospital, Fondation Asile des Aveugles, Department of Ophthalmology, University of Lausanne, Lausanne |
Commission cantonale d'Éthique de la Recherche sur l'être humain Vaud (CER-VD) | 23.02.2021 | ||||||
| 2020-02357 | Confocal microscopy: a new and innovating way to detect positive margins in non palpable breast cancer? | non clinical, involving persons | monocentric | A | Dr. Colin Simonson | Hôpital du Valais |
Hôpital du Valais, Sion, Sion |
Commission cantonale d'Éthique de la Recherche sur l'être humain Vaud (CER-VD) | 10.03.2021 | Study has ended | |||||
| 2020-02356 |
SAKK 38/19 Assessing a ctDNA and PET-oriented therapy in patients with DLBCL A multicenter, open-label, phase II trial |
clinical trial | drugs | phase 2 | multicentric | C | PD Dr. med. Anastasios Stathis | SAKK |
IOSI, Bellinzona Inselspital Bern, Bern Kantonsspital Aarau, Aarau Kantonsspital Olten, Olten Luzerner Kantonsspital, Luzern St. Claraspital, Basel Kantonsspital Baden, Baden Hopitaux Universitaire de More ... |
Comitato etico cantonale Ticino | Ethikkommission Nordwest- und Zentralschweiz EKNZ, Ethikkommission Ostschweiz (EKOS), Kantonale Ethikkommission Bern, Kantonale Ethikkommission Zürich, Commission cantonale d'Éthique de la Recherche s More ... | 11.05.2021 | |||
| 2020-02355 |
AGO-OVAR 2.29 / ENGOT-ov34 Atezolizumab in combination with Bevacizumab and Chemotherapy versus Bevacizumab and Chemotherapy in recurrent ovarian cancer – a randomized Phase III trial - An ENGOT Tria More ... |
clinical trial | drugs | phase 3 | multicentric | C | Prof. Dr. med. Christian Kurzeder | AGO Reearch GmbH - Ago Study Group |
Universitätsspital Basel, Basel Inselspital, Bern Kantonsspital Aarau AG, Aarau Kantonsspital Olten, Olten Tumor Zentrum Aarau - Hirslanden Medical Center, Aarau Luzerner Kantonsspital, Luzern Kantons More ... |
Ethikkommission Nordwest- und Zentralschweiz EKNZ | Ethikkommission Nordwest- und Zentralschweiz EKNZ, Ethikkommission Ostschweiz (EKOS), Kantonale Ethikkommission Bern, Kantonale Ethikkommission Zürich, Commission Cantonale d'éthique de la recherche G More ... | 15.01.2021 | |||
| 2020-02354 | Analyse des facteurs pronostiques dans le cancer non à petites cellules du poumon | personal data/biological material | monocentric | Prof Sabina Berezowska | CHUV - Institut |
Institute of Pathology, Lausanne |
Commission cantonale d'Éthique de la Recherche sur l'être humain Vaud (CER-VD) | 05.01.2021 | Study has ended | ||||||
| 2020-02353 | Aquablation vs. Holmium Laser Enucleation of the Prostate in the Treatment of Benign Prostatic Hyperplasia in medium to large size prostates: A prospective randomized trial | clinical trial | medical devices | monocentric | A1 | PD Dr. med. Daniel Engeler | KSSG |
Klinik für Urologie, Kantonsspital St. Gallen, 9007, St. Gallen |
Ethikkommission Ostschweiz (EKOS) | 05.10.2020 | |||||
| 2020-02352 | Intracranial Neuroendoscopy in Children and Adults: A Comparative Analysis | personal data/biological material | monocentric | PD Dr. med Jehuda Soleman | Neurochirurgie Universiätsspital Basel |
Universitätsspital, Basel |
Ethikkommission Nordwest- und Zentralschweiz EKNZ | 03.03.2021 | |||||||
| 2020-02351 | Studio pilota per la valutazione dell’efficacia del dispositivo medico Jalosome® Soothing gel, in termini di riduzione della lesione e dell’intensità del dolore, nonché del miglioramento della QoL, ne More ... | clinical trial | medical devices | monocentric | A1 | PhD Loris Bonetti | Welcare Industries S.p.A |
ISTITUTO ONCOLOGICO DELLA SVIZZERA ITALIANA, Bellinzona |
Comitato etico cantonale Ticino | 21.10.2020 | Study has ended | ||||