| BASEC ID | Project title | Type of project | Type of clinical trial | Study phase (clinical trials only) | multi- / monocentric | Category | Principal investigator | Sponsor | Investigational sites | Lead EC | Local EC(s) | Approval date | Minors | Study Ended | |
|---|---|---|---|---|---|---|---|---|---|---|---|---|---|---|---|
| 2020-01929 | A phase II, open label, single arm, single center study to evaluate pyrexia management (with or without any other cytokine release symptoms) using tocilizumab, an humanized monoclonal antibody against More ... | clinical trial | drugs | phase 2 | monocentric | A | Prof. Dr. Reinhard Dummer | Universitätsspital Zürich |
Dermatologische Klinik/ Universitätsspital Zürich, Züich |
Kantonale Ethikkommission Zürich | 22.09.2020 | Study has ended | |||
| 2020-01928 | Bakterielle Zusammensetzung des Mekoniums und der Brustmilch in Assoziation mit der mütterlichen Ernährung, der Schlafqualität sowie der subjektiven und objektiven Stressreaktion während der Schwanger More ... | non clinical, involving persons | monocentric | A | Prof. Dr. rer. nat. Ulrike Ehlert | Universität Zürich |
Psychologisches Institut, Universität Zürich, Oerlikon |
Kantonale Ethikkommission Zürich | 01.12.2020 | Study has ended | |||||
| 2020-01926 | A retrospective study on Transanal total mesorectal excision (TaTME) versus conventional laparoscopic total mesorectal excision TME (lapTME) in mid and low rectal cancer | personal data/biological material | monocentric | Prof Dr med Dimitri Christoforidis | EOC |
EOC, Lugano |
Comitato etico cantonale Ticino | 31.08.2020 | Study has ended | ||||||
| 2020-01925 | Effects of immortalized human islet-derived MSC (hISC)-conditioned medium (CM) on human beta cells | personal data/biological material | monocentric | Pr. Anne Wojtusciszyn | CHUV - Endocrinologie, |
Centre Hospitalier Universitaire Vaudois, Lausanne |
Commission cantonale d'Éthique de la Recherche sur l'être humain Vaud (CER-VD) | 28.09.2021 | |||||||
| 2020-01924 | Adenovirus persistence in human T cells | personal data/biological material | monocentric | Prof. Urs. F. Greber | UZH |
UZH, Zurich |
Kantonale Ethikkommission Zürich | 25.08.2020 | |||||||
| 2020-01922 | Ethics of communication & ethics in communication: An exploratory analysis of Advance Care Planning encounters | clinical trial | other clinical trials | monocentric | A | Anca-Cristina Sterie | Chaire de soins palliatifs gériatriques |
Lausanne University Hospital, Chaire de soins palliatifs gériatriques, Lausanne |
Commission cantonale d'Éthique de la Recherche sur l'être humain Vaud (CER-VD) | 30.10.2020 | Study has ended | ||||
| 2020-01921 | BO42864: A PHASE III, RANDOMIZED, OPEN-LABEL STUDY OF PRALSETINIB VERSUS STANDARD OF CARE FOR FIRST-LINE TREATMENT OF RET FUSION−POSITIVE, METASTATIC NON−SMALL CELL LUNG CANCER | clinical trial | drugs | phase 3 | monocentric | C | Dr. med. Ulrich Richter | Roche Pharma (Schweiz) AG |
Universitätsspital Zürich, Zürich |
Kantonale Ethikkommission Zürich | 06.10.2020 | ||||
| 2020-01920 |
Effects of Dapagliflozin on blood volume status and vascular function in clinically compensated heart failure patients after an acute heart failure event. DAPAGLIFLOZIN ON VOLUME VASCULAR OUTCOME More ... |
clinical trial | drugs | phase 4 | monocentric | C | Prof. Dr. med. Frank Ruschitzka | University Hospital Zurich |
Cardiology, Zurich |
Kantonale Ethikkommission Zürich | 15.10.2020 | ||||
| 2020-01919 | Bronchiectasis and Microbiome: a monocentric descriptive study | non clinical, involving persons | monocentric | A | Dre Jesica Mazza Stalder | CHUV - Pneumologie |
Centre universitaire vaudois, Lausanne |
Commission cantonale d'Éthique de la Recherche sur l'être humain Vaud (CER-VD) | 13.10.2020 | ||||||
| 2020-01918 | Evaluation of the surgical method: ultrasound-guided ultra-minimalinvasive thread carpal tunnel release | personal data/biological material | monocentric | Prof. Dirk Schaefer | University hospital Basel |
University Hospital Basel, Basel |
Ethikkommission Nordwest- und Zentralschweiz EKNZ | 09.10.2020 | |||||||
| 2020-01917 | Effects of the SGLT2 inhibitor empagliflozin in patients with euvolemic and hypervolemic hyponatremia – a monocentric randomized double-blind placebo-controlled trial - the EMPOWER study | clinical trial | drugs | phase 4 | multicentric | C | Dr. Julie Refardt | University Hospital Basel |
University Hospital Basel, Basel Spitalzentrum Biel, Biel/Bienne Luzerner Kantonsspital, Luzern CHUV, Lausanne |
Ethikkommission Nordwest- und Zentralschweiz EKNZ | Ethikkommission Nordwest- und Zentralschweiz EKNZ, Kantonale Ethikkommission Bern, Commission cantonale d'Éthique de la Recherche sur l'être humain Vaud (CER-VD) | 07.10.2020 | |||
| 2020-01916 | Vissuto dei famigliari durante la limitazione delle visite per il COVID-19 e percezione dell’utilità dell’incontro con i curanti dopo il decesso del proprio congiunto | non clinical, involving persons | monocentric | A | Prof. Dr. Med. Tiziano Cassina | Fondazione Cardiocentro Ticino |
Fondazione Cardiocentro Ticino, Lugano |
Comitato etico cantonale Ticino | 31.08.2020 | Study has ended | |||||
| 2020-01915 | Image-guided personalized medicine in Multiple Sclerosis | non clinical, involving persons | monocentric | A | PD Dr. med. Franca Wagner | Inselspital Bern |
Inselspital, Bern |
Kantonale Ethikkommission Bern | 08.12.2020 | ||||||
| 2020-01914 | Sichere Type & Screen Analyse aus Verwurfsprobe des ZVK | personal data/biological material | monocentric | Barbara Mihm | Stiftung Blutspende SRK AG-SO |
Stiftung Blutspende SRK AG-SO, Aarau |
Ethikkommission Nordwest- und Zentralschweiz EKNZ | 12.08.2020 | Study has ended | ||||||
| 2020-01913 | Acoustics-based drill state, screw stability and implant insertion analysis: a cadaver study | deceased persons | monocentric | Prof. Philipp Fürnstahl | Universitätsklinik Balgrist |
Universitätsklinik Balgrist, Zürich |
Kantonale Ethikkommission Zürich | 15.09.2020 | |||||||
| 2020-01912 |
The importance of monitoring wet AMD patients during COVID- 19 pandemic: A retrospective study of assessment of functional and structural outcomes. |
non clinical, involving persons | monocentric | A | Dr PD Aude Ambresin | Swissvisio Medical Retina Unit |
Swissvisio Medical retina unit, Lausanne |
Commission cantonale d'Éthique de la Recherche sur l'être humain Vaud (CER-VD) | 20.10.2020 | ||||||
| 2020-01911 | Intravitreal brolucizumab in patients with exudative non-responding age-related macular degeneration switched from aflibercept | non clinical, involving persons | monocentric | A | Dr Aude Ambresin | Swissvisio, medical retina unit |
Swissvisio Medical retina unit, Lausanne |
Commission cantonale d'Éthique de la Recherche sur l'être humain Vaud (CER-VD) | 03.11.2020 | ||||||
| 2020-01910 | A Phase 3, Randomized, Double-Blind, Trial of Pamrevlumab (FG-3019) or Placebo in Combination with Systemic Corticosteroids in Subjects with Non ambulatory Duchenne Muscular Dystrophy (DMD) | clinical trial | drugs | phase 3 | monocentric | C | PD Dr. med. Klein Andrea | FibroGen, Inc. |
Inselspital Universitätsspital Bern, Bern 3010 |
Kantonale Ethikkommission Bern | 29.03.2021 | yes | Study has ended | ||
| 2020-01909 | M20-178 A Randomized, Open-Label, Phase 3 Study Evaluating Efficacy and Safety of Navitoclax in Combination with Ruxolitinib Versus Best Available Therapy in Subjects with Relapsed/Refractory Myelofib More ... | clinical trial | drugs | phase 3 | multicentric | C | PD Dr. med. Dominik Heim | AbbVie AG |
Universitätsspital Basel, Basel Universitätsspital Bern, Bern |
Ethikkommission Nordwest- und Zentralschweiz EKNZ | Kantonale Ethikkommission Bern | 28.10.2021 | Study has ended | ||
| 2020-01908 | Deliberate updating of schematic memory with new emotional experiences: An experimental demonstration | non clinical, involving persons | monocentric | A | PD Dr. Ueli Kramer | CHUV - Psychiatrie |
Department of Psychiatry-CHUV, Lausanne |
Commission cantonale d'Éthique de la Recherche sur l'être humain Vaud (CER-VD) | 26.10.2020 | ||||||