| BASEC ID | Project title | Type of project | Type of clinical trial | Study phase (clinical trials only) | multi- / monocentric | Category | Principal investigator | Sponsor | Investigational sites | Lead EC | Local EC(s) | Approval date | Minors | Study Ended | |
|---|---|---|---|---|---|---|---|---|---|---|---|---|---|---|---|
| 2020-01699 | A study to evaluate the safety and efficacy of the tumor-targeting human antibody-cytokine fusion protein L19TNF plus standard temozolomide chemoradiotherapy in patients with newly diagnosed glioblast More ... | clinical trial | drugs | phase 1/2 | monocentric | C | Dr. Tobias Weiss | Philogen S.p.A. |
UniversitätsSpital Zürich, Zürich |
Kantonale Ethikkommission Zürich | 30.07.2020 | ||||
| 2020-01698 | Comparative bioavailability study of Sildenafil 100 mg oral film vs. Viagra® 100 mg film-coated tablet administered to healthy men under fed conditions | clinical trial | drugs | phase 1 | monocentric | B | Dr. Milko Radicioni | IBSA Institut Biochimique S.A. |
CROSS Research S.A. Phase I Unit, CH-6864 Arzo, Switzerland |
Comitato etico cantonale Ticino | 16.07.2020 | Study has ended | |||
| 2020-01696 | Identifying predictive markers for long-term mortality in patients with cerebrovascular disease. A retrospective analysis of patients from the Swiss Stroke Registry | personal data/biological material | monocentric | Prof Dr. med. Urs Fischer, MSc | Department of Neurology, Inselspital, University of Bern |
Inselspital, Department of Neurology, Bern |
Kantonale Ethikkommission Bern | 04.08.2020 | |||||||
| 2020-01695 | Neuro-behavioral basis of (multi)sensory-motor integration in humans | non clinical, involving persons | monocentric | A | Prof. Silvio IONTA | Fondation Asile des Aveugles - University of Lausanne |
Fondation Asile des Aveugles, Lausanne |
Commission cantonale d'Éthique de la Recherche sur l'être humain Vaud (CER-VD) | 28.09.2020 | ||||||
| 2020-01694 | Evaluation of Endo-FLIP to individualize per-oral endoscopic pyloromyotomy (G-POEM) or surgical pyloromyotomy and to predict therapeutic response in patients with refractory gastroparesis: POM-FLIP | non clinical, involving persons | monocentric | B | Prof. Dr. med. Reiner Wiest | Gastroenterologie |
Universitätsklinik für Viszerale Chirurgie und Medizin Bauchzentrum Bern, Inselspital, Bern |
Kantonale Ethikkommission Bern | 06.03.2023 | ||||||
| 2020-01693 | The Diagnostic Value and Feasibility of Dual-energy CT in the Differentiation of Metastatic from Benign small pulmonary nodules: Comparison with PET-scan | non clinical, involving persons | monocentric | A | PD Dr. Jon A. Lutz Médecin agréé | HFR - Hôpital cantonal Fribourg |
Clinique de chirurgie, Hôpital cantonale de Fribourg, Fribourg |
Commission cantonale d'Éthique de la Recherche sur l'être humain Vaud (CER-VD) | 14.07.2022 | ||||||
| 2020-01692 | Structural Studies of Human Brain in Neurodegeneration | personal data/biological material | monocentric | Prof. Henning Stahlberg | EPFL |
EPFL, Lausanne |
Commission cantonale d'Éthique de la Recherche sur l'être humain Vaud (CER-VD) | 17.08.2020 | |||||||
| 2020-01691 | Cerebrospinal fluid features in SARS-CoV-2 RT-PCR positive patients | personal data/biological material | monocentric | Doctor Manuel Schibler |
Geneva University Hospitals, Geneva |
Commission Cantonale d'éthique de la recherche Genève (CCER) | 04.08.2020 | Study has ended | |||||||
| 2020-01690 | Multimodal prehabilitation for major surgery in elderly patients to lower complications: A randomised, prospective, single-centre, multidisciplinary trial. | clinical trial | other clinical trials | monocentric | A | Dr. Dominique Engel | University Hospital Bern, Inselspital Bern |
Inselspital Berne, University of Berne, Berne |
Kantonale Ethikkommission Bern | 13.07.2021 | |||||
| 2020-01689 | Analysis of antimicrobial drug penetration in human body fluids and tissues | non clinical, involving persons | monocentric | A | Dr. Frédéric Lamoth | CHUV - Institut |
CHUV, Lausanne |
Commission cantonale d'Éthique de la Recherche sur l'être humain Vaud (CER-VD) | 22.07.2020 | ||||||
| 2020-01687 | Dapagliflozin and Myocardial Fat Content in Heart Failure with reduced Ejection Fraction Study | clinical trial | drugs | n/a | monocentric | B | associate Professor Roger Hullin M.D. executive eMBA FH CAS Heart failure | CHUV - Cardiologie |
CHUV, Lausanne |
Commission cantonale d'Éthique de la Recherche sur l'être humain Vaud (CER-VD) | 01.03.2022 | ||||
| 2020-01686 | DeID : De-identification of clinical narrative data in French, German, and Italian | personal data/biological material | monocentric | Jean-Philippe Goldman | Division of Medical Information Sciences (HUG & UNIGE) |
SIMED (HUG & UNIGE), Geneva |
Commission Cantonale d'éthique de la recherche Genève (CCER) | 21.10.2020 | Study has ended | ||||||
| 2020-01685 | Helicopter transferred patients suffering acute aortic dissection: A five-year, retrospective, single-center study. | personal data/biological material | monocentric | Kirsch Matthias | CHUV |
CHUV : Centre Hospitalier Universitaire Vaudois, Lausanne |
Commission cantonale d'Éthique de la Recherche sur l'être humain Vaud (CER-VD) | 15.12.2020 | |||||||
| 2020-01684 | Diagnostic, prognostic and predictive modelling for patient with COVID-19: multicentric prospective validation and new hypothesis-generating modelling – A multilayer Rapid Learning Health Care approac More ... | personal data/biological material | monocentric | Dr. Med. Carla Puligheddu | Ente Ospedaliero Cantonale |
EOC, Bellinzona |
Comitato etico cantonale Ticino | 08.09.2020 | |||||||
| 2020-01683 | Molecular Features of Multidrug-Resistant Enterobacterales Colonizing Swiss Expats and Their Relatives | non clinical, involving persons | monocentric | A | Prof. Andrea Endimiani | University of Bern |
University of Bern, Institut for Infectious Diseases, Bern |
Kantonale Ethikkommission Bern | 09.10.2020 | ||||||
| 2020-01682 | In vitro Fertilisation (IVF) – Analysis of follicular physiology in stimulated IVF therapies (conventional IVF) and in unstimulated IVF therapies (Natural Cycle IVF) | personal data/biological material | monocentric | Prof. Michael von Wolff | University Womens hospital, Inselspital |
University Womens hospital, Inselspital, Bern |
Kantonale Ethikkommission Bern | 08.09.2020 | |||||||
| 2020-01681 | Closed loop ventilation versus standard pressure support ventilation in SARS-CoV-2 ARDS | personal data/biological material | monocentric | Dr. med. Philipp Karl Buehler | Institute of Intensive Care Medicine |
Institute of intensive Care Medicine, Zurich |
Kantonale Ethikkommission Zürich | 28.07.2020 | |||||||
| 2020-01680 | Embodiment in monolingual and bilingual people with aphasia – making use of motor-language interaction therapy in L1 and L2 | clinical trial | other clinical trials | monocentric | A | Professor Jean-Marie Annoni | JHFR - Hôpital cantonal |
University of Fribourg, Fribourg |
Commission cantonale d'Éthique de la Recherche sur l'être humain Vaud (CER-VD) | 03.08.2020 | Study has ended | ||||
| 2020-01679 | Intraoperative assessment of the influence of cleft repair on microcirculation of the palate | non clinical, involving persons | monocentric | A | Dr. Benito Benitez | University Hospital Basel |
University Hospital Basel, Basel |
Ethikkommission Nordwest- und Zentralschweiz EKNZ | 30.07.2020 | yes | |||||
| 2020-01678 | COMB157G23101 - A single-arm, prospective, multicentre, open-label study to evaluate ofatumumab treatment effectiveness and patientreported outcomes in patients with relapsing multiple sclerosis trans More ... | clinical trial | drugs | phase 3 | multicentric | C | Prof. Dr. med. Tobias Derfuss | Novartis Pharma Schweiz AG |
Universitätsspital, Basel Kantonsspital St. Gallen, St. Gallen Centro Sclerosi Multipla, Ospedale Regionale di Lugano, Lugano |
Ethikkommission Nordwest- und Zentralschweiz EKNZ | Ethikkommission Ostschweiz (EKOS), Comitato etico cantonale Ticino | 17.11.2020 | Study has ended | ||