| BASEC ID | Project title | Type of project | Type of clinical trial | Study phase (clinical trials only) | multi- / monocentric | Category | Principal investigator | Sponsor | Investigational sites | Lead EC | Local EC(s) | Approval date | Minors | Study Ended | |
|---|---|---|---|---|---|---|---|---|---|---|---|---|---|---|---|
| 2022-00245 | Early prediction of chronic and refractory Immune Thrombocytopenia in pediatrics with machine learning | personal data/biological material | monocentric | Dr. med. Severin Kasser | Universitäts-Kinderspital beider Basel (UKBB) |
Universitäts-Kinderspital beider Basel (UKBB), Basel |
Ethikkommission Nordwest- und Zentralschweiz EKNZ | 28.02.2022 | |||||||
| 2022-00242 | Lymphvenöse Anastomosen bei Lappenrekonstruktionen vom postoperativen Defekt bei Sarkompatienten. | personal data/biological material | monocentric | pract. med. Audrius Poskevicius | Hirslanden Klinik St. Anna |
Hirslanden Klinik St. Anna, Luzern |
Ethikkommission Nordwest- und Zentralschweiz EKNZ | 22.03.2022 | |||||||
| 2022-00240 | FRONTIER 3 - Safety, efficacy and exposure of subcutaneously administered NNC0365-3769 (Mim8) prophylaxis in children with haemophilia A with or without FVIII inhibitors | clinical trial | drugs | phase 3 | monocentric | C | Dr. med. Freimut H. Schilling | Novo Nordisk Pharma AG |
Luzerner Kantonsspital, Luzern |
Ethikkommission Nordwest- und Zentralschweiz EKNZ | 31.05.2022 | yes | |||
| 2022-00238 | Mechanical, cardiorespiratory, and muscle oxygenation responses to a repeated sprint exercise with or without hand cooling under different hypoxic conditions: effects on DNA methylation levels | non clinical, involving persons | monocentric | A | PhD Fabio Borrani |
institut des siences du sport de l'université de Lausanne, Lausanne |
Commission cantonale d'Éthique de la Recherche sur l'être humain Vaud (CER-VD) | 24.03.2022 | |||||||
| 2022-00237 | Vascular Effects of Non-linear Periodized Exercise Training in Sedentary Adults with Elevated Cardiovascular Risk – The VascuFit Project. | clinical trial | other clinical trials | monocentric | A | Dr. med. Karsten Königstein | Sport und Bewegungsmedizin |
Department of Sport, Exercise and Health, Basel |
Ethikkommission Nordwest- und Zentralschweiz EKNZ | 07.04.2022 | |||||
| 2022-00236 | Developing an objective measure of experienced pain | clinical trial | other clinical trials | monocentric | A | Prof. Philippe Tobler | University of Zurich |
University of Zurich, Zurich |
Kantonale Ethikkommission Zürich | 10.05.2022 | |||||
| 2022-00235 | Delivery risk estimation in women admitted for threatened preterm labor: The PrePredict Study. A prediction model combining old and new clinical, ultrasonographic and biochemical parameters. | non clinical, involving persons | monocentric | A | Dr Océane Pécheux |
Geneva University Hospitals, Geneva |
Commission Cantonale d'éthique de la recherche Genève (CCER) | 28.07.2022 | |||||||
| 2022-00234 | SpineJack® versus percutaneous posterior instrumentation for osteoporotic and traumatic vertebral fractures with posterior wall injury | personal data/biological material | monocentric | Dr.med. Dominik Baschera | Luzerner Kantonsspital |
Luzerner Kantonsspital, Luzern |
Ethikkommission Nordwest- und Zentralschweiz EKNZ | 29.06.2022 | |||||||
| 2022-00232 | Patient reported outcome measures (PROMs) für die Rekonstruktion der unteren Extremität im klinischen Kontext | clinical trial | other clinical trials | monocentric | A | Prof. Dr. med. Nicole Lindenblatt | University Hospital Zurich |
University Hospital Zürich, Zürich |
Kantonale Ethikkommission Zürich | 06.05.2022 | |||||
| 2022-00231 | A Phase 3, Double-Blind, Multicenter Study to Evaluate the Efficacy and Safety of CAEL-101 and Plasma Cell Dyscrasia Treatment Versus Placebo and Plasma Cell Dyscrasia Treatment in Plasma Cell Dyscras More ... | clinical trial | drugs | phase 3 | multicentric | C | Dr. Med. Rahel Schwotzer | Caelum Biosciences Inc. |
University Hospital Zurich, Zurich Department of Hematology and Central Hematology Laboratory, University Hospital of Bern, Bern |
Kantonale Ethikkommission Zürich | Kantonale Ethikkommission Bern | 21.07.2022 | |||
| 2022-00230 | Temporalité et Morphologie Flexionnelle Verbale en Français : étude neuropsycholinguistique auprès de patients avec aphasie | non clinical, involving persons | monocentric | A | Prof. Mation Fossard | UNINE - FLSH - ISLo |
Université de Neuchâtel, Neuchâtel |
Commission cantonale d'Éthique de la Recherche sur l'être humain Vaud (CER-VD) | 07.04.2022 | ||||||
| 2022-00228 | CHDM201I12201 - A phase Ib/II open label dose confirmation, proof of concept study of siremadlin in combination with venetoclax plus azacitidine in unfit adult AML participants who responded sub-optim More ... | clinical trial | drugs | phase 1/2 | multicentric | C | Dr. med. Rouven Müller | Novartis Pharma Schweiz AG |
Universitätsspital Zürich, Zürich Inselspital Bern, Bern CHUV, Lausanne |
Kantonale Ethikkommission Zürich | Kantonale Ethikkommission Bern, Commission cantonale d'Éthique de la Recherche sur l'être humain Vaud (CER-VD) | 28.06.2022 | |||
| 2022-00225 | Perioperative Glycaemic Variability as a Physiologic Marker of Glucose-Insulin-Potassium Efficacy in Adult Cardiac Surgery: A Retrospective Study | personal data/biological material | monocentric | Dr Raoul Schorer | Hôpitaux Universitaires de Genève |
Hôpitaux Universitaires de Genève, Genève |
Commission Cantonale d'éthique de la recherche Genève (CCER) | 11.05.2022 | |||||||
| 2022-00223 | Place du ganglion sentinelle dans le cancer du sein : étude rétrospective comparant le double marquage au vert d’indocyanine et Bleu Patenté et le double marquage au 99mTc et Bleu Patenté, expérience More ... | personal data/biological material | monocentric | Fathi | Service de gynécologie et d'obstétrique, HFR Fribourg |
Khomsi, Fribourg |
Commission cantonale d'Éthique de la Recherche sur l'être humain Vaud (CER-VD) | 20.07.2022 | |||||||
| 2022-00222 | Die Etablierung des m(i)RNA-Profilings zur Identifizierung von Körperflüssigkeiten in der forensischen Fallarbeit | non clinical, involving persons | monocentric | A | Dr. Iris Schulz | IRM Basel |
Institut für Rechtsmedizin, Basel |
Ethikkommission Nordwest- und Zentralschweiz EKNZ | 29.03.2022 | ||||||
| 2022-00221 | Assessing new caries detection methods for posterior teeth using a hybrid reference standard_ in vivo pilot study. | non clinical, involving persons | monocentric | A | Abdel Aziz Marwa | Unige |
UniGe, Geneve |
Commission Cantonale d'éthique de la recherche Genève (CCER) | 21.03.2022 | ||||||
| 2022-00220 | Salivary allopregnanolone and mood across the peripartum in healthy pregnant women | non clinical, involving persons | monocentric | A | Prof. Dr. rer. nat. Ulrike Ehlert | Universität Zürich |
Universität Zürich, Zürich |
Kantonale Ethikkommission Zürich | 18.03.2022 | ||||||
| 2022-00218 | Machbarkeitsstudie zur Identifizierung fetaler kardiovaskulärer Anatomie mittels nicht gegateter dynamischer fetaler Magnetresonanztomographie des Herzens | personal data/biological material | monocentric | Prof. Dr. med. Julia Geiger | Kinderspital Zürich |
Kinderspital Zürich, Zürich |
Kantonale Ethikkommission Zürich | 04.03.2022 | |||||||
| 2022-00217 | Management of Acute Exacerbations of Chronic Obstructive Pulmonary Disease (AECOPD) in secondary care in a public hospital in Switzerland- a medical audit | personal data/biological material | monocentric | Prof. Dr. med. Jörg Daniel Leuppi |
Kantonsspital Baselland, Liestal |
Ethikkommission Nordwest- und Zentralschweiz EKNZ | 24.02.2022 | ||||||||
| 2022-00215 | “Connected caesarean section”: A link between mothers and their newborns to improve maternal childbirth experience: A pilot trial | clinical trial | other clinical trials | monocentric | A | Prof. Antje Horsch | IUFRS-UNIL- FBM - CHUV |
CHUV, Lausanne |
Commission cantonale d'Éthique de la Recherche sur l'être humain Vaud (CER-VD) | 10.03.2022 | |||||