| BASEC ID | Project title | Type of project | Type of clinical trial | Study phase (clinical trials only) | multi- / monocentric | Category | Principal investigator | Sponsor | Investigational sites | Lead EC | Local EC(s) | Approval date | Minors | Study Ended | |
|---|---|---|---|---|---|---|---|---|---|---|---|---|---|---|---|
| 2020-00347 | SPO - Swiss Personalized Oncology: exploratory data analysis (EDA) performed on multicenter oncology data. | personal data/biological material | multicentric | Prof. Dr. med.Dr.phil. Andreas Wicki |
Universitätsspital Zürich, Zürich Inselspital Bern, Bern University Hospital Basel USB, Basel Kantonsspital Liestal, Abteilung Hämatologie und Onkologie, Liestal Hôpital Universitaire de Genève, HUG, More ... |
Ethikkommission Nordwest- und Zentralschweiz EKNZ | Ethikkommission Nordwest- und Zentralschweiz EKNZ, Kantonale Ethikkommission Bern, Kantonale Ethikkommission Zürich, Commission cantonale d'Éthique de la Recherche sur l'être humain Vaud (CER-VD), Com More ... | 26.11.2020 | |||||||
| 2020-00345 | A Retrospective Evaluation of Vancomycin Therapeutic Drug Monitoring at the University Hospital Basel | personal data/biological material | monocentric | PD Dr. med. Anne Leuppi-Taegtmeyer | University Hospital Basel |
University Hospital Basel, Basel |
Ethikkommission Nordwest- und Zentralschweiz EKNZ | 07.10.2020 | |||||||
| 2020-00344 | GS-US-365-4237: A Phase 2, Blinded, Randomized, Placebo-Controlled Study Evaluating the Efficacy and Safety of GS-4875 in Subjects with Moderately to Severely Active Ulcerative Colitis | clinical trial | drugs | phase 2 | multicentric | C | PD Dr. med. Luc Biedermann | Gilead Sciences, Inc. |
USZ, Zürich Berner IBD Study Group, Berne Inselspital, Berne |
Kantonale Ethikkommission Zürich | Kantonale Ethikkommission Bern | 18.06.2020 | Study has ended | ||
| 2020-00343 | Predictive factors of cirrhosis regression in patients with advanced chronic liver disease | personal data/biological material | monocentric | Prof. Dr. med. Annalisa Berzigotti | Bern Center for Precision Medicine |
UVCM Hepatologie, 3010 Bern |
Kantonale Ethikkommission Bern | 09.06.2020 | Study has ended | ||||||
| 2020-00342 | A Phase 2b/3 Prospective, Randomised, Double-Blind, Sham-Controlled Trial of VTS270 (2-hydroxypropyl-β-cyclodextrin) in Subjects with Neurological Manifestations of Niemann-Pick Type C1 (NPC1) Disease | clinical trial | drugs | phase 2 | monocentric | C | Dr. med. et phil. nat. Matthias Gautschi | Vtesse LLC, a Mallinckrodt Pharmaceutical Company |
INSELSPITAL, Universitätsspital Bern, Bern |
Kantonale Ethikkommission Bern | 03.07.2020 | yes | Study has ended | ||
| 2020-00341 | A Multicenter, Open-label, Randomized Phase 2 Study to Compare the Efficacy and Safety of Lenvatinib in Combination with Ifosfamide and Etoposide versus Ifosfamide and Etoposide in Children, Adolescen More ... | clinical trial | drugs | phase 2 | multicentric | C | Dr. Nicolas U. Gerber | Eisai Ltd |
Abteilung für Onkologie Universitäts-Kinderspital, Zürich CHUV (centre hospitalier universitaire Vaudois) , Départment femme-mère-enfant, Service de pédiatrie, Unité d'hématologie oncologie pédiatriqu More ... |
Kantonale Ethikkommission Zürich | Commission cantonale d'Éthique de la Recherche sur l'être humain Vaud (CER-VD) | 16.07.2020 | yes | Study has ended | |
| 2020-00340 | Bridging plate in complex wrist fracture: long term follow up | non clinical, involving persons | monocentric | A | Pr Jean-Yves Beaulieu | Hôpitaux Universitaires de Genève |
Hôpitaux Universitaires de Genève, Geneva |
Commission Cantonale d'éthique de la recherche Genève (CCER) | 18.05.2020 | ||||||
| 2020-00339 | Encorafenib plus binimetinib in patients with locally advanced, unresectable or metastatic BRAFV600-mutated melanoma: a multi-centric, national, prospective, longitudinal, non-interventional study in More ... | non clinical, involving persons | multicentric | A | Dr. med. Sofiya Latifyan | Pierre Fabre Pharma AG |
Centre Hospitalier Universitaire Vaudois (CHUV) Division d’oncologie personalisée analytique, 1011 Lausanne Universitätsklinik für Dermatologie, Inselspital, 3010 Bern Kantonsspital Aarau, Onkologie, More ... |
Commission cantonale d'Éthique de la Recherche sur l'être humain Vaud (CER-VD) | Ethikkommission Nordwest- und Zentralschweiz EKNZ, Ethikkommission Ostschweiz (EKOS), Kantonale Ethikkommission Bern, Kantonale Ethikkommission Zürich, Commission cantonale d'Éthique de la Recherche s More ... | 13.05.2020 | |||||
| 2020-00338 |
The PISCES Study: A Multicenter Phase 2, Open-Label Study of Intratumoral Tavokinogene Telseplasmid (tavo, pIL-12) plus Electroporation in Combination with Intravenous Pembrolizumab in Patients wit More ... |
clinical trial | gene therapy | monocentric | C | Prof. Dr. Reinhard Dummer | Oncosec Medical Incorporated |
USZ Zurich Airport, Dermatology, Zurich |
Kantonale Ethikkommission Zürich | 28.09.2021 | Study has ended | ||||
| 2020-00337 |
Sepsis and septic shock in the elderly patients: care trajectory : predicting factors. Sepsis et choc septique du sujet âgé aux HUG : facteurs influençant la trajectoire de soins. |
personal data/biological material | monocentric | Dr Xavier Roux | HUG |
HUG, Geneva |
Commission Cantonale d'éthique de la recherche Genève (CCER) | 23.08.2021 | |||||||
| 2020-00336 | Dépistage MRSA avec le test rapide Xpert MRSA: Faut-il considérer les faux positifs? | personal data/biological material | monocentric | Dominique Blanc | CHUV |
CHUV, Lausanne |
Commission cantonale d'Éthique de la Recherche sur l'être humain Vaud (CER-VD) | 27.05.2020 | Study has ended | ||||||
| 2020-00335 | TRI0223 - Multi-specific antibodies for harnessing T cells in lymphoma humanized mice | personal data/biological material | monocentric | PhD Elisabetta Traggiai | Novartis Pharma AG - NIBR |
Novartis Pharma AG - NIBR, NIBR |
Ethikkommission Nordwest- und Zentralschweiz EKNZ | 04.03.2020 | |||||||
| 2020-00334 | L’ACCELEROMETRIE POUR L’IDENTIFICATION DES PREFERENCES® NATURELLES : AERIENNE – TERRIENNE ET MEMBRE INFERIEUR PROPULSEUR – SUPPORT | non clinical, involving persons | monocentric | A | Dr. / Davide / Malatesta | Volodalen |
UNIL, Lausanne |
Commission cantonale d'Éthique de la Recherche sur l'être humain Vaud (CER-VD) | 29.06.2020 | Study has ended | |||||
| 2020-00333 | Red Blood Cell Transfusion in Obstetrics and its Implication for Patient Blood Management: A Retrospective Analysis in Switzerland from 1998 to 2016 | personal data/biological material | monocentric | Prof. Dr. med. Daniel Surbek | University Hospital Bern, Inselspital |
University Hospital Bern, Inselspital, Bern |
Kantonale Ethikkommission Bern | 19.05.2020 | |||||||
| 2020-00332 | Follow-up of intraductal papillary mucinous neoplasms (IPMN) of the pancreas – a retrospective observational study | personal data/biological material | monocentric | Prof Dr med Bernhard Egger | HFR Fribourg |
HFR Fribourg, Villars-sur-Glâne |
Commission cantonale d'Éthique de la Recherche sur l'être humain Vaud (CER-VD) | 18.05.2020 | Study has ended | ||||||
| 2020-00331 | Source and network analyses of epileptic activity during wakefulness and sleep | personal data/biological material | monocentric | Pr Serge Vulliémoz | Hôpitaux Universitaires de Genève |
Hôpitaux Universitaires de Genève, Genève |
Commission Cantonale d'éthique de la recherche Genève (CCER) | 07.04.2020 | |||||||
| 2020-00330 | Identification and characterization of human sperm variation and its role in embryonic development. | non clinical, involving persons | monocentric | A | Prof. Christian de Geyter | University Hospital Basel |
University Hospital, University of Basel, Basel |
Ethikkommission Nordwest- und Zentralschweiz EKNZ | 03.08.2020 | ||||||
| 2020-00329 | DEVELOPMENT, IMPLEMENTATION AND OUTCOME OF A MULTIFUNCTIONAL AGENT WITH ALERT-BASED ALGORITHMS FOR ELECTRONIC PARACETAMOL ORDERS IN A TERTIARY CARE HOSPITAL IN SWITZERLAND | personal data/biological material | monocentric | Dr. med. Alireza Salili | Kantonsspital Aarau |
Medizinische Uniklinik, Kantonsspital, Aarau |
Ethikkommission Nordwest- und Zentralschweiz EKNZ | 17.03.2020 | |||||||
| 2020-00328 | Patient Specific Optimized Therapy (PSOT) Study | non clinical, involving persons | monocentric | A | Dr. Angelo Auricchio | EPD Solutions (Philips Medical System) |
Cardiocentro Ticino, Lugano |
Comitato etico cantonale Ticino | 18.06.2020 | Study has ended | |||||
| 2020-00327 | Evaluation of InterStim Micro System Performance and Safety (ELITE) | non clinical, involving persons | monocentric | A | Dr.med. Lukas Marti | Medtronic, Inc. |
Kantonsspital St. Gallen, Klinik für Allgemein-, Viszeral-, Endokrin- und Transplantationschirurgie, St. Gallen |
Ethikkommission Ostschweiz (EKOS) | 20.08.2020 | Study has ended | |||||