| BASEC ID | Project title | Type of project | Type of clinical trial | Study phase (clinical trials only) | multi- / monocentric | Category | Principal investigator | Sponsor | Investigational sites | Lead EC | Local EC(s) | Approval date | Minors | Study Ended | |
|---|---|---|---|---|---|---|---|---|---|---|---|---|---|---|---|
| 2022-00162 | Combined beta- plus Auger electron therapy using a novel somatostatin receptor subtype 2 antagonist labelled with terbium-161 (161Tb-DOTA-LM3): Beta plus Study | clinical trial | drugs | n/a | monocentric | C | Dr. med. Julia Fricke | Universitätsspital Basel |
Division of Nuclear Medicine, University Hospital of Basel, Basel |
Ethikkommission Nordwest- und Zentralschweiz EKNZ | 31.03.2022 | ||||
| 2022-00160 | The effect of cooling with a bed topper and linen on itch in clinical routine - an exploratory study | clinical trial | other clinical trials | monocentric | A | PD Dr. med. Simon Mueller | University Hospital Basel |
University Hospital Basel, Basel |
Ethikkommission Nordwest- und Zentralschweiz EKNZ | 22.03.2022 | |||||
| 2022-00159 | Analysis of plasma proteins associated to DNA repair in Alzheimer’s disease | personal data/biological material | monocentric | PD Dr. Paolo Paganetti | Laboratori di Ricerca Traslazionale EOC |
Laboratori di Ricerca Traslazionale EOC, Bellinzona |
Comitato etico cantonale Ticino | 18.02.2022 | |||||||
| 2022-00158 | Kesimpta® (Ofatumumab) in Swiss Multiple sclerosis patients – an Observational Study (KOSMOS) | non clinical, involving persons | multicentric | A | Dr. Petra Stellmes | Novartis Pharma Schweiz AG |
Neurologie Loewenplatz, Luzern Inselspital Bern Universitätsklinik für Neurologie, Bern Luzerner Kantonspital, Luzern Neurobaden Praxis für Neurologie, Baden-Dättwil Neurologische Praxis Zug, Zug Neur More ... |
Ethikkommission Nordwest- und Zentralschweiz EKNZ | Ethikkommission Nordwest- und Zentralschweiz EKNZ, Ethikkommission Ostschweiz (EKOS), Kantonale Ethikkommission Bern, Kantonale Ethikkommission Zürich, Commission cantonale d'Éthique de la Recherche s More ... | 16.03.2022 | |||||
| 2022-00157 | PRophylactic cerebral Irradiation or active MAgnetic resonance imaging surveillance in small-cell Lung cancer patients (PRIMALung study) | clinical trial | other clinical trials | multicentric | A | Andratschke Nicolaus | European Organisation for Research and Treatment of Cancer (EORTC) |
UniversitaetsSpital Zurich, Zurich Inselspital, Bern University Hospital, Bern Kantonsspital St Gallen, St Gallen Reseau Hospitalier Neuchatelois - RHNe - La Chaux de Fonds, La Chaux-de-Fonds |
Kantonale Ethikkommission Zürich | Ethikkommission Ostschweiz (EKOS), Kantonale Ethikkommission Bern, Commission cantonale d'Éthique de la Recherche sur l'être humain Vaud (CER-VD) | 01.07.2022 | ||||
| 2022-00156 | Assessment of reward responses to oral erythritol using flavor preference learning and its effects on gastrointestinal hormones, glycemic control, appetite-related sensations and emotional state | clinical trial | other clinical trials | monocentric | A | PD Dr. Anne Christin Meyer-Gerspach | St. Clara Research Ltd |
St. Clara Research Ltd, Basel |
Ethikkommission Nordwest- und Zentralschweiz EKNZ | 25.02.2022 | |||||
| 2022-00155 |
Two cohort registry study for patients with advanced CSCC treated with Cemiplimab or other approaches |
non clinical, involving persons | multicentric | A | M.D. Egle Ramelyte | sanofi-aventis (schweiz) ag |
GUSZ Flughafen Dermatologische Klinik, 8058 Zürich Insel Gruppe AG, Universitätsklinik für Dermatologie, Freiburgstrasse, Bern Kantonspital Aarau AG, Aarau Universitätsspital, Basel Kantonsspital, St. More ... |
Kantonale Ethikkommission Zürich | Ethikkommission Nordwest- und Zentralschweiz EKNZ, Ethikkommission Ostschweiz (EKOS), Kantonale Ethikkommission Bern | 04.03.2022 | |||||
| 2022-00153 | Analysis of clinical-pathological features and response to treatments in an international cohort of patients affected by NUTM1-rearranged carcinomas: a multicentric retrospective observational study | personal data/biological material | monocentric | PD Dr. Med. Anastasios Stathis | Fondazione IRCCS Istituto Nazionale dei Tumori di Milano |
Istituto Oncologico della Svizzera Italiana, Bellinzona |
Comitato etico cantonale Ticino | 16.02.2022 | |||||||
| 2022-00152 | Biomechanical Comparison of Anterior Cruciate Ligament Reconstruction Using a Single Bundle Round or Ribbon-Like Hamstring Graft | deceased persons | monocentric | PD Dr med Peter Koch | Gelenkzentrum Winterthur AG |
numex GmbH, Winterhur |
Kantonale Ethikkommission Zürich | 04.03.2022 | |||||||
| 2022-00151 | Évaluation du niveau osseux résiduel autour des implants explantés : facteurs de risque locaux et systémiques | personal data/biological material | monocentric | Pr Catherine Giannopoulou | Université de Genève |
Clinique Universitaire de Médecine Dentaire, Faculté de Médecine, Genève |
Commission Cantonale d'éthique de la recherche Genève (CCER) | 02.03.2022 | |||||||
| 2022-00150 | Early versus deferred aortic valve replacement in patients with moderate aortic stenosis combined with mitral regurgitation: a randomized clinical trial | clinical trial | other clinical trials | multicentric | B | Prof. Thomas Pilgrim | Insel Gruppe AG |
Insel Gruppe AG, Bern Hôpital Cantonal de Genève, Genève |
Kantonale Ethikkommission Bern | Commission Cantonale d'éthique de la recherche Genève (CCER) | 20.04.2022 | ||||
| 2022-00149 | Pilot study for investigation of clinical factors associated with Contact Lens Discomfort | non clinical, involving persons | monocentric | A | Prof. Dr. Daniela Nosch | Menicon Co. Ltd. R&D Innovation centre |
Institut für Optometrie, FHNW, Olten |
Ethikkommission Nordwest- und Zentralschweiz EKNZ | 10.02.2022 | ||||||
| 2022-00148 | Investigating the potency of Ichnos Sciences bi- and tri- specific antibodies, in an ex vivo model of patient-derived tumour cell killing in Haematological malignancies. | personal data/biological material | monocentric | Dr Myriam Chimen | Ichnos Sciences Biotherapeutics SA |
Ichnos Sciences, Epalinges |
Commission cantonale d'Éthique de la Recherche sur l'être humain Vaud (CER-VD) | 08.03.2022 | |||||||
| 2022-00147 | Analyse des facteurs d’influence exogènes sur la pratique des expertises de crédibilité réalisées chez des mineurs qui allèguent des violences sexuelles. | personal data/biological material | monocentric | Ms Emilie Wouters | CHUV |
CHUV, Prilly |
Commission cantonale d'Éthique de la Recherche sur l'être humain Vaud (CER-VD) | 26.04.2022 | |||||||
| 2022-00146 |
Screen exposure in the first year of life of children born very prematurely Exposition aux écrans dans la première année de vie des enfants nés très prématurément |
non clinical, involving persons | monocentric | A | Docteur Cristina Borradori Tolsa | HUG - Hôpital des enfants |
HUG, Geneva |
Commission Cantonale d'éthique de la recherche Genève (CCER) | 03.03.2022 | yes | |||||
| 2022-00145 | Agility Training for Older Adults: A Randomized Controlled Trial | clinical trial | other clinical trials | monocentric | A | Prof. Dr. Oliver Faude | University of Basel |
University of Basel, Basel |
Ethikkommission Nordwest- und Zentralschweiz EKNZ | 15.03.2022 | |||||
| 2022-00144 | Evaluate the reliability of a method for assessing the perception of muscle contraction in the lower limb | non clinical, involving persons | monocentric | A | PhD Francis Degache | MotionLab |
MotionLab, Le Mont-sur-Lausanne |
Commission cantonale d'Éthique de la Recherche sur l'être humain Vaud (CER-VD) | 02.05.2022 | ||||||
| 2022-00142 |
LADON distal radius Lets Agree to Disagree on Operative versus Nonoperative (LADON) treatment for distal radius fractures in the elderly. |
non clinical, involving persons | multicentric | A | PD Dr Frank Beeres | Luzerner Kantonsspital |
Luzerner Kantonsspital, Luzern Kantonsspital Obwalden, Sarnen Kantonsspital Graubünden, Chur |
Ethikkommission Nordwest- und Zentralschweiz EKNZ | Ethikkommission Nordwest- und Zentralschweiz EKNZ, Kantonale Ethikkommission Zürich | 06.04.2022 | |||||
| 2022-00140 | Predictive value of Nu.Q™ biomarkers to help guiding the management of complex osteoarticular infections: a monocentric prospective observational cohort study | non clinical, involving persons | monocentric | A | Prof. Jacques Schrenzel | VolitionRx |
Geneva University Hospitals, Geneva |
Commission Cantonale d'éthique de la recherche Genève (CCER) | 16.08.2022 | ||||||
| 2022-00139 | MK-1026-003: A Phase 2 Study to Evaluate the Efficacy and Safety of MK-1026 in Participants with Hematologic Malignancies | clinical trial | drugs | phase 2 | multicentric | C | Prof. Dr. med. Thorsten Zenz | Merck Sharp & Dohme LLC Whitehouse Station, NJ (USA) |
Universitätsspital Zürich, Zürich Inselspital, Bern Instituto Oncologico della Svizzera Italiana (IOSI), Bellinzona |
Kantonale Ethikkommission Zürich | Kantonale Ethikkommission Bern, Comitato etico cantonale Ticino | 05.04.2022 | |||