BASEC ID Project title Type of project Type of clinical trial Study phase (clinical trials only) multi- / monocentric Category Principal investigator Sponsor Investigational sites Lead EC Local EC(s) Approval date Minors Study Ended
2022-00162 Combined beta- plus Auger electron therapy using a novel somatostatin receptor subtype 2 antagonist labelled with terbium-161 (161Tb-DOTA-LM3): Beta plus Study clinical trial drugs n/a monocentric C Dr. med. Julia Fricke Universitätsspital Basel Division of Nuclear Medicine, University Hospital of Basel, Basel
Ethikkommission Nordwest- und Zentralschweiz EKNZ 31.03.2022
2022-00160 The effect of cooling with a bed topper and linen on itch in clinical routine - an exploratory study clinical trial other clinical trials monocentric A PD Dr. med. Simon Mueller University Hospital Basel University Hospital Basel, Basel
Ethikkommission Nordwest- und Zentralschweiz EKNZ 22.03.2022
2022-00159 Analysis of plasma proteins associated to DNA repair in Alzheimer’s disease personal data/biological material monocentric PD Dr. Paolo Paganetti Laboratori di Ricerca Traslazionale EOC Laboratori di Ricerca Traslazionale EOC, Bellinzona
Comitato etico cantonale Ticino 18.02.2022
2022-00158 Kesimpta® (Ofatumumab) in Swiss Multiple sclerosis patients – an Observational Study (KOSMOS) non clinical, involving persons multicentric A Dr. Petra Stellmes Novartis Pharma Schweiz AG Neurologie Loewenplatz, Luzern
Inselspital Bern Universitätsklinik für Neurologie, Bern
Luzerner Kantonspital, Luzern
Neurobaden Praxis für Neurologie, Baden-Dättwil
Neurologische Praxis Zug, Zug
Neur More ...
Ethikkommission Nordwest- und Zentralschweiz EKNZ Ethikkommission Nordwest- und Zentralschweiz EKNZ, Ethikkommission Ostschweiz (EKOS), Kantonale Ethikkommission Bern, Kantonale Ethikkommission Zürich, Commission cantonale d'Éthique de la Recherche s More ... 16.03.2022
2022-00157 PRophylactic cerebral Irradiation or active MAgnetic resonance imaging surveillance in small-cell Lung cancer patients (PRIMALung study) clinical trial other clinical trials multicentric A Andratschke Nicolaus European Organisation for Research and Treatment of Cancer (EORTC) UniversitaetsSpital Zurich, Zurich
Inselspital, Bern University Hospital, Bern
Kantonsspital St Gallen, St Gallen
Reseau Hospitalier Neuchatelois - RHNe - La Chaux de Fonds, La Chaux-de-Fonds
Kantonale Ethikkommission Zürich Ethikkommission Ostschweiz (EKOS), Kantonale Ethikkommission Bern, Commission cantonale d'Éthique de la Recherche sur l'être humain Vaud (CER-VD) 01.07.2022
2022-00156 Assessment of reward responses to oral erythritol using flavor preference learning and its effects on gastrointestinal hormones, glycemic control, appetite-related sensations and emotional state clinical trial other clinical trials monocentric A PD Dr. Anne Christin Meyer-Gerspach St. Clara Research Ltd St. Clara Research Ltd, Basel
Ethikkommission Nordwest- und Zentralschweiz EKNZ 25.02.2022
2022-00155 Two cohort registry study for patients with advanced CSCC treated
with Cemiplimab or other approaches
non clinical, involving persons multicentric A M.D. Egle Ramelyte sanofi-aventis (schweiz) ag GUSZ Flughafen Dermatologische Klinik, 8058 Zürich
Insel Gruppe AG, Universitätsklinik für Dermatologie, Freiburgstrasse, Bern
Kantonspital Aarau AG, Aarau
Universitätsspital, Basel
Kantonsspital, St. More ...
Kantonale Ethikkommission Zürich Ethikkommission Nordwest- und Zentralschweiz EKNZ, Ethikkommission Ostschweiz (EKOS), Kantonale Ethikkommission Bern 04.03.2022
2022-00153 Analysis of clinical-pathological features and response to treatments in an international cohort of patients affected by NUTM1-rearranged carcinomas: a multicentric retrospective observational study personal data/biological material monocentric PD Dr. Med. Anastasios Stathis Fondazione IRCCS Istituto Nazionale dei Tumori di Milano Istituto Oncologico della Svizzera Italiana, Bellinzona
Comitato etico cantonale Ticino 16.02.2022
2022-00152 Biomechanical Comparison of Anterior Cruciate Ligament Reconstruction Using a Single Bundle Round or Ribbon-Like Hamstring Graft deceased persons monocentric PD Dr med Peter Koch Gelenkzentrum Winterthur AG numex GmbH, Winterhur
Kantonale Ethikkommission Zürich 04.03.2022
2022-00151 Évaluation du niveau osseux résiduel autour des implants explantés : facteurs de risque locaux et systémiques personal data/biological material monocentric Pr Catherine Giannopoulou Université de Genève Clinique Universitaire de Médecine Dentaire, Faculté de Médecine, Genève
Commission Cantonale d'éthique de la recherche Genève (CCER) 02.03.2022
2022-00150 Early versus deferred aortic valve replacement in patients with moderate aortic stenosis combined with mitral regurgitation: a randomized clinical trial clinical trial other clinical trials multicentric B Prof. Thomas Pilgrim Insel Gruppe AG Insel Gruppe AG, Bern
Hôpital Cantonal de Genève, Genève
Kantonale Ethikkommission Bern Commission Cantonale d'éthique de la recherche Genève (CCER) 20.04.2022
2022-00149 Pilot study for investigation of clinical factors associated with Contact Lens Discomfort non clinical, involving persons monocentric A Prof. Dr. Daniela Nosch Menicon Co. Ltd. R&D Innovation centre Institut für Optometrie, FHNW, Olten
Ethikkommission Nordwest- und Zentralschweiz EKNZ 10.02.2022
2022-00148 Investigating the potency of Ichnos Sciences bi- and tri- specific antibodies, in an ex vivo model of patient-derived tumour cell killing in Haematological malignancies. personal data/biological material monocentric Dr Myriam Chimen Ichnos Sciences Biotherapeutics SA Ichnos Sciences, Epalinges
Commission cantonale d'Éthique de la Recherche sur l'être humain Vaud (CER-VD) 08.03.2022
2022-00147 Analyse des facteurs d’influence exogènes sur la pratique des expertises de crédibilité réalisées chez des mineurs qui allèguent des violences sexuelles. personal data/biological material monocentric Ms Emilie Wouters CHUV CHUV, Prilly
Commission cantonale d'Éthique de la Recherche sur l'être humain Vaud (CER-VD) 26.04.2022
2022-00146 Screen exposure in the first year of life of children born very prematurely

Exposition aux écrans dans la première année de vie des enfants nés très prématurément
non clinical, involving persons monocentric A Docteur Cristina Borradori Tolsa HUG - Hôpital des enfants HUG, Geneva
Commission Cantonale d'éthique de la recherche Genève (CCER) 03.03.2022 yes
2022-00145 Agility Training for Older Adults: A Randomized Controlled Trial clinical trial other clinical trials monocentric A Prof. Dr. Oliver Faude University of Basel University of Basel, Basel
Ethikkommission Nordwest- und Zentralschweiz EKNZ 15.03.2022
2022-00144 Evaluate the reliability of a method for assessing the perception of muscle contraction in the lower limb non clinical, involving persons monocentric A PhD Francis Degache MotionLab MotionLab, Le Mont-sur-Lausanne
Commission cantonale d'Éthique de la Recherche sur l'être humain Vaud (CER-VD) 02.05.2022
2022-00142 LADON distal radius
Lets Agree to Disagree on Operative versus Nonoperative (LADON) treatment for distal radius fractures in the elderly.
non clinical, involving persons multicentric A PD Dr Frank Beeres Luzerner Kantonsspital Luzerner Kantonsspital, Luzern
Kantonsspital Obwalden, Sarnen
Kantonsspital Graubünden, Chur
Ethikkommission Nordwest- und Zentralschweiz EKNZ Ethikkommission Nordwest- und Zentralschweiz EKNZ, Kantonale Ethikkommission Zürich 06.04.2022
2022-00140 Predictive value of Nu.Q™ biomarkers to help guiding the management of complex osteoarticular infections: a monocentric prospective observational cohort study non clinical, involving persons monocentric A Prof. Jacques Schrenzel VolitionRx Geneva University Hospitals, Geneva
Commission Cantonale d'éthique de la recherche Genève (CCER) 16.08.2022
2022-00139 MK-1026-003: A Phase 2 Study to Evaluate the Efficacy and Safety of MK-1026 in Participants with Hematologic Malignancies clinical trial drugs phase 2 multicentric C Prof. Dr. med. Thorsten Zenz Merck Sharp & Dohme LLC Whitehouse Station, NJ (USA) Universitätsspital Zürich, Zürich
Inselspital, Bern
Instituto Oncologico della Svizzera Italiana (IOSI), Bellinzona
Kantonale Ethikkommission Zürich Kantonale Ethikkommission Bern, Comitato etico cantonale Ticino 05.04.2022