| BASEC ID | Project title | Type of project | Type of clinical trial | Study phase (clinical trials only) | multi- / monocentric | Category | Principal investigator | Sponsor | Investigational sites | Lead EC | Local EC(s) | Approval date | Minors | Study Ended | |
|---|---|---|---|---|---|---|---|---|---|---|---|---|---|---|---|
| 2023-01493 | Single Centre Drug-Drug Interaction study with Levothyroxine/Magnesium-Citrate and Levothyroxine/Magnesium-Aspartate in healthy subjects | clinical trial | drugs | n/a | monocentric | B | Dr. med. Jérôme Bonzon | USZ |
USZ, Zürich |
Kantonale Ethikkommission Zürich | 06.10.2023 | ||||
| 2023-01491 | Diagnostische Milzbiopsien am Kantonsspital St. Gallen und am Kantonsspital Winterthur: Retrospektive Erfassung der Risikofaktoren und Erhebung der Patientenzufriedenheit zur Erarbeitung einer Informa More ... | personal data/biological material | multicentric | Prof. Dr. med. Felicitas Hitz | Kantonsspital St. Gallen |
Kantonsspital St. Gallen, St. Gallen Kantonsspital Winterthur, Winterthur |
Ethikkommission Ostschweiz (EKOS) | Kantonale Ethikkommission Zürich | 16.11.2023 | ||||||
| 2023-01489 | CAAA617D12302: An International, Prospective, Open-label, Multi-center, Randomized Phase III Study comparing lutetium (177Lu) vipivotide tetraxetan (AAA617) versus Observation to delay castration or d More ... | clinical trial | drugs | phase 3 | multicentric | B | PD Dr. med. Janusch Blautzik | Novartis Pharma Schweiz AG |
Hirslanden Klinik St. Anna, Luzern Hôpitaux universitaire de Genève, Geneva Stadtspital Zürich,, Zürich |
Ethikkommission Nordwest- und Zentralschweiz EKNZ | Kantonale Ethikkommission Zürich, Commission Cantonale d'éthique de la recherche Genève (CCER) | 22.11.2023 | |||
| 2023-01488 | Single Centre Retrospective Analysis of Aortic Valve Repairs and Replacements in Neonatal, Infant and Paediatric Patients | personal data/biological material | monocentric | Prof. Dr. med. univ Martin Schweiger | University Children's Hospital Zurich |
University Children's Hospital Zurich, Zurich |
Kantonale Ethikkommission Zürich | 09.02.2024 | |||||||
| 2023-01486 | The role of Helicobacter pylori infection on gastrointestinal symptoms and complications in patients after gastric bypass surgery | personal data/biological material | monocentric | med. pract. Azin Navaei | Stoffwechselpraxis Luzern |
Stoffwechselpraxis Luzern, Luzern |
Ethikkommission Nordwest- und Zentralschweiz EKNZ | 05.10.2023 | |||||||
| 2023-01485 | Nur gezielte oder gezielte & systematische Prostatabiopsien: prädiktiver Wert von mpMRI und klinischen Parametern für die Notwendigkeit der systematischen Biopsie. | personal data/biological material | monocentric | Prof. Irene A. Burger | Nuklearmedizin |
Kantonsspital Baden, Baden |
Ethikkommission Nordwest- und Zentralschweiz EKNZ | 03.10.2023 | |||||||
| 2023-01484 | Association of ultrasound features of the myometrium suggestive of adenomyosis and clinical symptoms | non clinical, involving persons | monocentric | A | Prof Dr Gwendolin Manegold-Brauer | SWISS GO TRIAL GROUP |
Universitätsspital Basel, Basel |
Ethikkommission Nordwest- und Zentralschweiz EKNZ | 31.01.2024 | ||||||
| 2023-01483 | eVOLVE-Meso - A Phase III, Randomized, Open-Label, Multicenter, Global Study of Volrustomig (MEDI5752) in Combination with Carboplatin plus Pemetrexed Versus Platinum plus Pemetrexed or Nivolumab plus More ... | clinical trial | drugs | phase 3 | multicentric | C | Prof. Dr. med. Martin Früh | AstraZeneca AG |
Kantonsspital St. Gallen, St. Gallen Inselspital, Universitätsspital Bern, Bern HFR, Freiburg Universitätsspital Basel, Basel Kantonsspital Baden, Baden |
Ethikkommission Ostschweiz (EKOS) | Ethikkommission Nordwest- und Zentralschweiz EKNZ, Kantonale Ethikkommission Bern | 02.11.2023 | |||
| 2023-01482 |
Erfahrungsbericht des neurochirurgischen Managements spinaler Frakturen sowie deskriptive Analyse von klinischen, bildgebenden und strahlenschutzrelevanten Parametern beim Einsatz des SpineJac More ... |
personal data/biological material | monocentric | PD Dr. med. Markus Bruder | Kantonsspital Aarau |
Kantonsspital Aarau, Aarau |
Ethikkommission Nordwest- und Zentralschweiz EKNZ | 14.09.2023 | |||||||
| 2023-01481 |
Toward technology enhanced patient information with 3D printed and mixed reality models in neuro-oncology |
non clinical, involving persons | monocentric | A | Dr. med. Lukas Andereggen | Kantonsspital Aarau |
Kantonsspital Aarau, Aarau |
Ethikkommission Nordwest- und Zentralschweiz EKNZ | 04.10.2023 | ||||||
| 2023-01480 | Covid-19 Schutzmassnahmen während der vierten Welle mit dem Vorherrschen der Deltavariante in einer Milizformation der Schweizer Armee | personal data/biological material | monocentric | MD Michael P. Brönnimann | Inselspital Bern |
DIPR Inselspital, Bern |
Kantonale Ethikkommission Bern | 20.09.2023 | |||||||
| 2023-01479 | Do stricter criteria for intraoperative parathyroid hormone assays prevent persistent hyperparathyroidism? Evaluation of an alternative protocol. | personal data/biological material | monocentric | Dr. med. Henning Wolf | Kantonsspital Aarau |
Kantonsspital Aarau, Aarau |
Ethikkommission Nordwest- und Zentralschweiz EKNZ | 08.09.2023 | |||||||
| 2023-01478 | 20200105 - A Phase 3, Open-label, Multicenter, Randomized Study to Evaluate the Efficacy and Safety of Romosozumab Compared with Bisphosphonates in Children and Adolescents With Osteogenesis Imperfec More ... | clinical trial | drugs | phase 3 | multicentric | C | Dr. med. Aline Bregou | Amgen Switzerland AG |
Centre Hospitalier Universitaire Vaudois, Lausanne Universitäts-Kinderspital beider Basel, Basel |
Commission cantonale d'Éthique de la Recherche sur l'être humain Vaud (CER-VD) | Ethikkommission Nordwest- und Zentralschweiz EKNZ | 06.02.2024 | yes | ||
| 2023-01477 | Navigated percutaneous screw fixation combined with total hip arthroplasty for not reconstructable acetabular fractures in geriatric patients | personal data/biological material | monocentric | PD Dr. med. Peter Wahl | Kantonsspital Winterthur |
Kantonsspital Winterthur, Winterthur |
Kantonale Ethikkommission Zürich | 11.01.2024 | |||||||
| 2023-01476 | Characteristics and prognosis of "acute promyelocytic-leukemia-like" (APL-like) NPM1-mutated acute myeloid leukemia (NPM1m-AML) | personal data/biological material | monocentric | Dre Vasiliki Papadopoulou | CHUV |
CHUV, Lausanne |
Commission cantonale d'Éthique de la Recherche sur l'être humain Vaud (CER-VD) | 08.09.2023 | |||||||
| 2023-01475 | Child and parent emotion-related risk and resilience factors associated with the transition from acute to chronic pain after surgery: A prospective longitudinal study | non clinical, involving persons | multicentric | A | PD Dr. Helen Koechlin | University Children's Hospital Zurich |
University Children's Hospital, Zurich University Children's Hospital, Basel University Hospital Balgrist, Zurich |
Kantonale Ethikkommission Zürich | Ethikkommission Nordwest- und Zentralschweiz EKNZ, Kantonale Ethikkommission Zürich | 24.11.2023 | yes | ||||
| 2023-01472 | Feasibility of a motor-cognitive training program in patients with traumatic brain injury during acute hospitalization | clinical trial | other clinical trials | monocentric | A | Dr. Eleftheria Giannouli | Kantonspital St. Gallen |
ETH Zurich, Zurich |
Ethikkommission Ostschweiz (EKOS) | 08.08.2023 | |||||
| 2023-01471 | Performance of continuous glucose monitoring Free Style Libre 3 and DexcomG7 in patients with diabetes mellitus on haemodialysis | non clinical, involving persons | monocentric | A | Dr. med. Elena Gamarra | Ente Ospedaliero Cantonale |
Ente Ospedaliero Cantonale, Ospedale Italiano, Viganello |
Comitato etico cantonale Ticino | 09.02.2024 | ||||||
| 2023-01470 | Development of an AI tool for the identification and characterization of intracorporeal drug containers (“body-packets”) | personal data/biological material | monocentric | Prof. Pierre-Alexandre Poletti |
Service de radiologie, HUG, Genève |
Commission Cantonale d'éthique de la recherche Genève (CCER) | 16.04.2024 | ||||||||
| 2023-01469 | Randomized, Open-label, Multicenter, Phase 3 Trial of Repotrectinib Versus Crizotinib in Participants with Locally Advanced or Metastatic Tyrosine Kinase Inhibitor TKI)-naïve ROS1-positive Non-Small C More ... | clinical trial | drugs | phase 3 | monocentric | C | Prof. Dr. Dr. Sacha Rothschild | Bristol-Myers Squibb Services Unlimited Company |
Kantonsspital Baden AG, Baden |
Ethikkommission Nordwest- und Zentralschweiz EKNZ | 07.12.2023 | ||||