| BASEC ID | Project title | Type of project | Type of clinical trial | Study phase (clinical trials only) | multi- / monocentric | Category | Principal investigator | Sponsor | Investigational sites | Lead EC | Local EC(s) | Approval date | Minors | Study Ended | |
|---|---|---|---|---|---|---|---|---|---|---|---|---|---|---|---|
| 2020-00033 | Clinical outcome prediction and phenotyping in arthritis using different machine learning strategies: an analysis of the SCQM dataset. | personal data/biological material | monocentric | Prof. Thomas Hügle | CHUV - Rhumatologie |
Rheumatology, CHUV, Lausanne |
Commission cantonale d'Éthique de la Recherche sur l'être humain Vaud (CER-VD) | 03.04.2020 | |||||||
| 2020-00032 | Non-inferiority of ultrasound for the diagnosis of upper extremity fractures in children | clinical trial | other clinical trials | monocentric | A | David Troxler | Universitäts-Kinderspital beider Basel |
Universitätsspital beider Basel, Basel |
Ethikkommission Nordwest- und Zentralschweiz EKNZ | 18.03.2020 | yes | Study has ended | |||
| 2020-00031 | Identification of novel mediators of inflammation and epithelial barrier function in chronic rhinosinusitis | personal data/biological material | monocentric | PD Dr. Michael Soyka | Universität Zürich |
UZH/USZ, Zürich |
Kantonale Ethikkommission Zürich | 17.02.2020 | |||||||
| 2020-00029 | A piloty study to examine synovial fluid extracellular vesicles as new diagnostic approach for knee osteoarthritis | non clinical, involving persons | monocentric | A | Prof. Christian Candrian | EOC |
Ospedale Regionale di Lugano, EOC, Lugano |
Comitato etico cantonale Ticino | 26.03.2020 | Study has ended | |||||
| 2020-00027 | Recognition of Thoracolumbar Spine Injury on CT Scout Views in Blunt Trauma | personal data/biological material | monocentric | Prof. Wolf Hautz | UNZ Inselspital Bern |
UNZ Inselspital Bern, Bern |
Kantonale Ethikkommission Bern | 21.04.2020 | |||||||
| 2020-00026 | MK-3475-02B: A Phase 1/2 Open-Label Rolling-Arm Umbrella Platform Design of Investigational Agents With or Without Pembrolizumab or Pembrolizumab Alone in Participants with Melanoma: Substudy 02B | clinical trial | drugs | phase 1/2 | multicentric | C | Prof. Dr. med. Reinhard Dummer | Merck Sharp & Dohme LLC |
UniversitätsSpital Zürich, Zürich Hôpitaux Universitaires de Genève (HUG), Genève Centre Hospitalier Universitaire Vaudois (CHUV), Lausanne |
Kantonale Ethikkommission Zürich | Commission cantonale d'Éthique de la Recherche sur l'être humain Vaud (CER-VD), Commission Cantonale d'éthique de la recherche Genève (CCER) | 02.04.2020 | |||
| 2020-00025 |
Improving communication toward ICU families to facilitate understanding and reduce stress. A multicenter observational, prospective study (Studio osservazionale, prospettico, multicentrico, per la va More ... |
non clinical, involving persons | monocentric | A | Dr. med. Marco Previsdomini |
Medicina intensiva ORBV, Bellinzona |
Comitato etico cantonale Ticino | 28.01.2020 | |||||||
| 2020-00023 | Salutogenèse et promotion de la santé un exemple chez les RMNA | non clinical, involving persons | monocentric | A | Joëlle Dubach |
Université de Genève, Delémont |
Ethikkommission Nordwest- und Zentralschweiz EKNZ | 14.05.2020 | |||||||
| 2020-00022 | Retrospective benchmarking study for Rapid Recovery of Fragility Hip Fractures in Europe | personal data/biological material | monocentric | Dr.med. Till Berk | UniversitätsSpital Zürich |
University Hospital Zurich, Zurich |
Kantonale Ethikkommission Zürich | 05.02.2020 | |||||||
| 2020-00021 | Early miscarriage in women after different fertility treatments (EARLYMIS) | personal data/biological material | monocentric | MSc Vera Mitter | Universitätsklinik für Frauenheilkunde |
University Hospital, Bern |
Kantonale Ethikkommission Bern | 27.02.2020 | |||||||
| 2020-00020 | Somatic mosaicism in human prion disease | deceased persons | monocentric | Prof. Adriano Aguzzi |
University Hospital of Zurich, Institute of Neuropathology, Zürich |
Kantonale Ethikkommission Zürich | 03.03.2020 | ||||||||
| 2020-00019 | MK-3475-02A: A Phase 1/2 Open-Label Rolling-Arm Umbrella Platform Design of Investigational Agents With or Without Pembrolizumab or Pembrolizumab Alone in Participants with Melanoma: Substudy 02A | clinical trial | drugs | phase 1/2 | multicentric | C | Prof. Dr. med Reinhard Dummer | Merck Sharp & Dohme LLC |
UniversitätsSpital Zürich, Zürich Hôpitaux Universitaires de Genève (HUG), Genève Centre Hospitalier Universitaire Vaudois (CHUV), Lausanne |
Kantonale Ethikkommission Zürich | Commission cantonale d'Éthique de la Recherche sur l'être humain Vaud (CER-VD), Commission Cantonale d'éthique de la recherche Genève (CCER) | 02.04.2020 | |||
| 2020-00018 | Wirksamkeit einer Behandlung mit Biologika, Signalübermittlungshemmer und konventionelle Immunsuppressiva bei rheumatoider Arthritis (RA) in der schweizerischen Kohorte SCQM. | personal data/biological material | monocentric | Prof/Diego/Kyburz |
Universitätsspital Basel, Basel |
Ethikkommission Nordwest- und Zentralschweiz EKNZ | 09.01.2020 | ||||||||
| 2020-00017 | Establishment of a LVAD destination program in a Swiss non cardiac transplant university hospital: 5 year experience | personal data/biological material | monocentric | Prof. Dr. Martin Grapow | Herzchirurgie Basel |
Hirslanden Zürich, Zürich |
Ethikkommission Nordwest- und Zentralschweiz EKNZ | 21.01.2020 | |||||||
| 2020-00015 | Treatment of anastomotic leakage after esophagectomy (TENTACLE esophagus) and after low anterior resection (TENTACLE rectum) | personal data/biological material | monocentric | Dr. Nicola Colucci |
Visceral Surgery, surgical department, Geneva University Hospital, Geneva |
Commission Cantonale d'éthique de la recherche Genève (CCER) | 24.02.2020 | ||||||||
| 2020-00014 | Circulating tumor cells in cancer | non clinical, involving persons | multicentric | A | PD Dr. med Marcus Vetter | University Hospital Basel |
Kantonsspital Baselland, Liestal, Liestal Kantonsspital Baselland, Liestal, Liestal |
Ethikkommission Nordwest- und Zentralschweiz EKNZ | Ethikkommission Nordwest- und Zentralschweiz EKNZ | 22.06.2020 | |||||
| 2020-00013 | MK-3475-02C: A Phase 1/2 Open-Label Rolling-Arm Umbrella Platform Design of Investigational Agents With or Without Pembrolizumab or Pembrolizumab Alone in Participants with Melanoma: Substudy 02C | clinical trial | drugs | phase 1/2 | multicentric | C | Prof. Dr. med. Reinhard Dummer | Merck Sharp & Dohme LLC |
UniversitätsSpital Zürich, Zürich Hôpitaux Universitaires de Genève (HUG), Genève Centre Hospitalier Universitaire Vaudois (CHUV), Lausanne |
Kantonale Ethikkommission Zürich | Commission cantonale d'Éthique de la Recherche sur l'être humain Vaud (CER-VD), Commission Cantonale d'éthique de la recherche Genève (CCER) | 02.04.2020 | |||
| 2020-00012 | Effekt auf den Glaskörper und die Retina einer Verhinderung eines Augendruckabfalls während der Kataraktoperation | personal data/biological material | monocentric | Prof. Dr. med. Daniel Mojon | Augenärzte am Bahnhof St. Gallen |
Augenärzte am Bahnhof, St.Gallen |
Ethikkommission Ostschweiz (EKOS) | 14.01.2020 | |||||||
| 2020-00009 | Pilotstudie zur Vergleichbarkeit eines Blutdruckmess-Algorithmus (RIVA Digital) mit konventionellen manschettenbasierten Blutdruckmessungen (Masterthese) | non clinical, involving persons | monocentric | A | PD Dr. med. Michael Mayr | Universitätsspital Basel |
Universitätsspital Basel, Basel |
Ethikkommission Nordwest- und Zentralschweiz EKNZ | 16.06.2020 | ||||||
| 2020-00008 | A Comparison of Ventricular Function in the Apical 4 Chamber and Subcostal 4 Chamber TTE Views: A Pilot Study. | non clinical, involving persons | monocentric | A | Eckhard Mauermann |
University Hospital Basel, Basel |
Ethikkommission Nordwest- und Zentralschweiz EKNZ | 05.08.2020 | |||||||