| BASEC ID | Project title | Type of project | Type of clinical trial | Study phase (clinical trials only) | multi- / monocentric | Category | Principal investigator | Sponsor | Investigational sites | Lead EC | Local EC(s) | Approval date | Minors | Study Ended | |
|---|---|---|---|---|---|---|---|---|---|---|---|---|---|---|---|
| 2023-01446 | A Randomized, Double-blind, Placebo-controlled, 12-month Phase 3 Study to Evaluate the Effect of Venglustat on Neuropathic and Abdominal Pain in Male and Female Participants ≥16 Years of Age with Fabr More ... | clinical trial | drugs | phase 3 | monocentric | C | PD Dr. med. Albina Nowak-Wilhelm | Sanofi-Aventis Recherche & Développement |
Universitäts Spital Zürich, Zürich |
Kantonale Ethikkommission Zürich | 09.02.2024 | yes | |||
| 2023-01443 | Defining Benchmarks for Simultaneous Pancreas- and Kidney Transplantation | personal data/biological material | monocentric | Dr. med. Fabian Rössler | Universitätsspital Zürich - Department of Surgery and Transplantation |
Universitätsspital Zürich, Zürich |
Kantonale Ethikkommission Zürich | 06.10.2023 | |||||||
| 2023-01442 | Untersuchung von Komorbiditäten, Lebensstil- und Umweltfaktoren bei AQP4-AK und MOG-AK vermittelten Neuromyelitis optica Spektrum Erkrankungen | non clinical, involving persons | monocentric | A | Dr. Marina Herwerth |
Klinik für Neurologie, Universitätsspital Zürich, Zürich |
Kantonale Ethikkommission Zürich | 22.09.2023 | |||||||
| 2023-01441 | Taste and Smell Deficits in Neurological Disease and Healthy Controls | non clinical, involving persons | monocentric | A | Professor Paolo Gasparini | Lake Lucerne Institute |
Lake Lucerne Institute, Lucerne |
Ethikkommission Nordwest- und Zentralschweiz EKNZ | 25.01.2024 | ||||||
| 2023-01440 | Swiss Sjoegren Cohort | non clinical, involving persons | multicentric | A | Dr. Lisa Christ | Department of Rheumatology and Immunology, University Hospital Bern, Inselspital |
Department of Rheumatology and Immunology, University Hospital Bern, Inselspital, Bern Universitätsspital Basel, Department Rheumatologie, Basel Kantonsspital Aarau, Klinik für Rheumatologie und Immun More ... |
Kantonale Ethikkommission Bern | Ethikkommission Nordwest- und Zentralschweiz EKNZ, Kantonale Ethikkommission Zürich, Commission cantonale d'Éthique de la Recherche sur l'être humain Vaud (CER-VD), Commission Cantonale d'éthique de l More ... | 05.10.2023 | |||||
| 2023-01439 | Infant-type hemispheric glioma: An international individual patient data meta-analysis investigating prognostic factors | personal data/biological material | monocentric | PD Dr Andre von Bueren | HUG |
HUG, Switzerland |
Commission Cantonale d'éthique de la recherche Genève (CCER) | 07.08.2023 | |||||||
| 2023-01437 | Comparison of IB Lab PANDA© and BoneXpert© software for bone age estimation of radiographs of the left hand in children | personal data/biological material | monocentric | PD Dr. med. Jasmin Busch | Insel Gruppe AG |
Inselspital, Bern |
Kantonale Ethikkommission Bern | 17.10.2023 | |||||||
| 2023-01436 |
Companion Diagnostic, Biocartis BC-020066 : Idylla™ EGFR_IUO/3.20 Mutation Test a Clinical Trial Assay in the AstraZeneca Phase III NeoADAURA Clinical Trial (D516AC00001) Clinical Study Protocol |
personal data/biological material | monocentric | Ekaterina Gelman | Biocartis NV |
Labcorp CLS, Meyrin |
Commission Cantonale d'éthique de la recherche Genève (CCER) | 14.08.2023 | Study has ended | ||||||
| 2023-01435 | ALCL-VBL: International cooperative prospective study for children and adolescents with standard risk ALK-positive anaplastic large cell lymphoma (ALCL) estimating the efficacy of Vinblastine | clinical trial | drugs | phase 3 | multicentric | C | PD Dr. med. Francesco Ceppi | German Pediatric Oncology Group GPOH gGmbH |
CHUV, Lausanne Inselspital Bern, Bern Kantonsspital Aarau, Aarau Universitäts-Kinderspital beider Basel UKBB, Basel Luzerner Kantonsspital, Luzern HUG Hôpitaux Universitaires Genève, Geneva Ostschweiz More ... |
Commission cantonale d'Éthique de la Recherche sur l'être humain Vaud (CER-VD) | Ethikkommission Nordwest- und Zentralschweiz EKNZ, Ethikkommission Ostschweiz (EKOS), Kantonale Ethikkommission Bern, Kantonale Ethikkommission Zürich, Commission Cantonale d'éthique de la recherche G More ... | 12.12.2023 | yes | ||
| 2023-01433 | Immunological characterisation of CAR T-cell therapy in patients with B-cell malignancies (ICCAR-T study) | non clinical, involving persons | monocentric | A | PD Dr. med. Urs Steiner |
Department of Rheumatology and Immunology, University Hospital Bern, Bern |
Kantonale Ethikkommission Bern | 20.12.2023 | |||||||
| 2023-01432 |
Thirst in Patients with Heart Failure A cross sectional study assessing the intensity, frequency, and distress caused by thirst in patients with heart failure |
non clinical, involving persons | monocentric | A | Annina Strickler | Universitätsspital Zürich (USZ) |
Universitätsspital Zürich (USZ), Zürich |
Kantonale Ethikkommission Zürich | 19.09.2023 | ||||||
| 2023-01431 |
Kardiorenales Syndrom: Arten, Risikofaktoren, pathophysiologische Mechanismen, Therapien und Patient*innenergebnisse |
personal data/biological material | monocentric | Elena Rho | University Hospital Zurich |
Division of Nephrology University Hospital Zürich, Zürich |
Kantonale Ethikkommission Zürich | 31.10.2023 | |||||||
| 2023-01430 | Tic&Tac | personal data/biological material | monocentric | Dr. Myriam Chimen | La Société des Produits Nestlé |
La Société des Produits Nestlé, Lausanne |
Commission cantonale d'Éthique de la Recherche sur l'être humain Vaud (CER-VD) | 09.08.2023 | |||||||
| 2023-01428 | The role of contextual information and arousal systems in unusual perceptual experiences | non clinical, involving persons | monocentric | A | Prof. Philipp Sterzer | UPK Basel |
UPK Basel, Basel |
Ethikkommission Nordwest- und Zentralschweiz EKNZ | 12.09.2023 | ||||||
| 2023-01427 | Automated speech analysis to monitor Movement disorders symptoms and optimize deep brain stimulation (DBS) – SPEECH-MD | personal data/biological material | monocentric | Prof. Dr. med. Paul Krack | Inselspital |
Inselspital, Bern |
Kantonale Ethikkommission Bern | 25.08.2023 | |||||||
| 2023-01425 | Matched-Pair-Analyse des lympho-nodal metastasierten Vulvakarzinoms bezüglich seiner pathogenetischen Subtypen zur Evaluierung von immunhistochemischen Markern der epithelial- mesenchymalen Transition More ... | personal data/biological material | monocentric | Prof. Dr. Christine Brambs | Luzerner Kantonsspital |
Luzerner Kantonsspital, Luzern |
Ethikkommission Nordwest- und Zentralschweiz EKNZ | 30.08.2023 | |||||||
| 2023-01424 | False positive serology for connective tissue diseases in patients receiving intravenous immunoglobulin | personal data/biological material | monocentric | Dr. Caroline Berkemeier | University Hospital Basel |
Universitätsspital Basel, Basel |
Ethikkommission Nordwest- und Zentralschweiz EKNZ | 27.07.2023 | |||||||
| 2023-01422 | Analisi molecolari per analizzare i fattori predittivi di risposta all’immunoterapia nei pazienti affetti da tumore della sfera ORL (testa-collo) all’Istituto Oncologico della Svizzera italiana. | personal data/biological material | monocentric | Dr. med. Vittoria Espeli | Instituto Oncologico della Svizzera Italiana (IOSI) |
Istituto Oncologico della Svizzera Italiana (IOSI), Bellinzona |
Comitato etico cantonale Ticino | 13.09.2023 | |||||||
| 2023-01421 | PREcooPera:A Window-of-Opportunity trial of giredestrant +/- triptorelin vs. anastrozole + triptorelin in premenopausal patients with ER-positive/HER2-negative early breast cancer | clinical trial | drugs | phase 2 | multicentric | C | Prof. Dr. med. Peter Dubsky | ETOP IBCSG Partner foundation |
Hirslanden Klinik St. Anna, Luzern Kantonsspital Baden, Department of Gynecology, Baden Brustzentrum Basel Bethesda Spital, Basel Spital Thurgau, Frauenfeld Instituto Oncologico della Swizzera Italian More ... |
Ethikkommission Nordwest- und Zentralschweiz EKNZ | Ethikkommission Nordwest- und Zentralschweiz EKNZ, Ethikkommission Ostschweiz (EKOS), Kantonale Ethikkommission Zürich, Commission cantonale d'Éthique de la Recherche sur l'être humain Vaud (CER-VD), More ... | 09.10.2023 | |||
| 2023-01419 | Hybrid breast reconstruction using reverse expansion and autologous fat grafting: a single center consecutive data analysis | non clinical, involving persons | monocentric | A | Professor Yves Harder | EOC |
EOC, Viganello |
Comitato etico cantonale Ticino | 30.10.2023 | ||||||