| BASEC ID | Project title | Type of project | Type of clinical trial | Study phase (clinical trials only) | multi- / monocentric | Category | Principal investigator | Sponsor | Investigational sites | Lead EC | Local EC(s) | Approval date | Minors | Study Ended | |
|---|---|---|---|---|---|---|---|---|---|---|---|---|---|---|---|
| 2025-02161 | Full-Thickness Macular Hole Surgery: Visual Acuity Gain and Categorial Visual Acuity Improvement Rates in Real-World Swiss Care | personal data/biological material | monocentric | Prof. Dr. med. Andreas Ebneter |
Department of Ophthalmology HOCH-Cantonal Hospital St. Gallen, St. Gallen |
Ethikkommission Ostschweiz (EKOS) | 30.10.2025 | ||||||||
| 2025-02155 | A multicentre study of the prognostic value of juxtacortical paramagnetic rims (JPR) in multiple sclerosis. | personal data/biological material | monocentric | Prof. Cristina Granziera | Research Center for Clinical Neuroimmunology and Neuroscience Basel |
RC2NB - Research Center for Clinical Neuroimmunology and Neuroscience Basel, Basel |
Ethikkommission Nordwest- und Zentralschweiz EKNZ | 12.11.2025 | |||||||
| 2025-02152 | Renal cell carcinoma preclinical in vitro and ex vivo models | personal data/biological material | monocentric | Prof. Dr. med. Beat Roth | Inselspital , University Hospital of Bern |
Inselspital, University Hospital of Bern, Bern |
Kantonale Ethikkommission Bern | 27.11.2025 | |||||||
| 2025-02142 | Quantification of the Keyhole Concept in Cranial Neurosurgery | clinical trial | other clinical trials | monocentric | A | Dr. Jonathan Rychen | Universitätsspital Basel |
University Hospital Basel, Basel |
Ethikkommission Nordwest- und Zentralschweiz EKNZ | 01.12.2025 | |||||
| 2025-02138 | Longitudinal assessment of the Edinburgh Cognititve and Behavioural Amyotrophic Lateral Sclerosis screen (ECAS), version A, B and C | non clinical, involving persons | monocentric | A | Oleksandra Hoptar | HOCH Health Ostschweiz, Kantonsspital St. Gallen Kantonsspital St. Gallen, Muskelzentrum/ALS Clinic |
HOCH Health Ostschweiz, Kantonsspital St. Gallen, Muskelzentrum/ALS Clinic, St. Gallen |
Ethikkommission Ostschweiz (EKOS) | 23.10.2025 | ||||||
| 2025-02133 | Clinicogenomic prediction modelling in pancreatic cancer – an explorative retrospective cohort study | personal data/biological material | monocentric | Dr. med. Christoph Kümmerli | Clarunis Universitäres Bauchzentrum Basel |
Clarunis Universitäres Bauchzentrum Basel, Basel |
Ethikkommission Nordwest- und Zentralschweiz EKNZ | 04.12.2025 | |||||||
| 2025-02131 |
Stress shielding patterns and risk factors in anatomic total shoulder arthroplasty |
personal data/biological material | monocentric | PhD Dr. med. Matthijs Jacxsens | HOCH Health Ostschweiz |
HOCH Health Ostschweiz, St. Gallen |
Ethikkommission Ostschweiz (EKOS) | 23.10.2025 | |||||||
| 2025-02127 |
Tige Fémorale Modulaire, Conique, Cannelée, Non Cimentée (Restoration Stryker®) avec Cupule Hémisphérique à Double Mobilité (Symbol, Dedienne Santé ®) dans les révisions de PTH: Survie d’implant à More ... |
personal data/biological material | monocentric | Prof. Julien Wegrzyn | CHUV |
CHUV, Lausanne |
Commission cantonale d'Éthique de la Recherche sur l'être humain Vaud (CER-VD) | 27.10.2025 | |||||||
| 2025-02120 | Vacuum Bell Therapy as a Non-Surgical Alternative for Pectus Excavatum: Real-World Experience | personal data/biological material | monocentric | Dr. med. Konstantinos Gioutsos | Thoracic Surgery |
Inselspital, Bern University Hospital, Bern |
Kantonale Ethikkommission Bern | 14.11.2025 | |||||||
| 2025-02114 | Tracheostomy after bilateral lung transplantation: timing impact on short- and long-term outcomes in a retrospective single center cohort | personal data/biological material | monocentric | Prof. Thorsten Krueger | CHUV - Chirurgie Thoracique |
CHUV, Lausanne |
Commission cantonale d'Éthique de la Recherche sur l'être humain Vaud (CER-VD) | 27.10.2025 | |||||||
| 2025-02113 | Retrospektive Outcome-Analyse erwachsener Patienten nach allogener Stammzelltransplantation am Luzerner Kantonsspital 2014-2023 | personal data/biological material | monocentric | Lucas Simeon | LUKS Spitalbetriebe AG |
Luzerner Kantonsspital LUKS, Luzern |
Ethikkommission Nordwest- und Zentralschweiz EKNZ | 24.11.2025 | |||||||
| 2025-02108 | FEASIBILITY OF SUBJECTIVE REFRACTION MEASUREMENT WITH LIGHTFIELD TECHNOLOGY – STUDY II | non clinical, involving persons | monocentric | A | Prof. Dr. Daniela Nosch | Institut für Optometrie, FHNW |
Institut für Optometrie, Hochschule für Technik, FHNW, 4600 Olten |
Ethikkommission Nordwest- und Zentralschweiz EKNZ | 19.11.2025 | ||||||
| 2025-02102 | Vergleich robotischer und offener Gastrektomie hinsichtlich des Outcomes der Anastomosentechnik – eine retrospektive Kohortenstudie (2016–2025) (Masterarbeit) | personal data/biological material | monocentric | Dr. Marko Kraljevic | Clarunis |
Clarunis, Basel |
Ethikkommission Nordwest- und Zentralschweiz EKNZ | 03.11.2025 | |||||||
| 2025-02099 |
Historische Vergleichskohorte 2018–2019 zur Einordnung der INTUK-Endpunkte in einen natürlichen Versorgungsverlauf (Weiterverwendung von Routinedaten gemäss HFG Art. 34) |
personal data/biological material | monocentric | Prof. Dr. med. Michael Rufer | Triaplus AG - Klinik Zugersee |
Triaplus AG - Klinik Zugersee, Oberwil b. Zug |
Ethikkommission Nordwest- und Zentralschweiz EKNZ | 16.10.2025 | |||||||
| 2025-02098 | "The APHRODITE critria" revisited - results of a large single center cohort of infertile males | personal data/biological material | monocentric | Dr. med. James Geiger | Universitätsspital Basel Frauenklinik Reproduktionsmedizin und gynäkologische Endokrinologie |
Universitätsspital Basel Frauenklinik Reproduktionsmedizin und gynäkologische Endokrinologie, Basel |
Ethikkommission Nordwest- und Zentralschweiz EKNZ | 24.11.2025 | |||||||
| 2025-02094 | TRI0395 - Evaluation of ps6 IHC on FFPE Tumor Samples as Clinical Biomarker for Selected Inhibitors of mutated PI3Kα For Clinical Efficacy Improvement in mut-PIJ3CA HR+ Breast Cancer Patients | personal data/biological material | monocentric | Ernesta Dammassa | Novartis Pharma AG - Biomedical Research |
Novartis Pharma AG - Biomedical Research, Basel |
Ethikkommission Nordwest- und Zentralschweiz EKNZ | 15.10.2025 | |||||||
| 2025-02087 | Retrospective single-center study to evaluate changes in T-cell immunophenotype with aging | personal data/biological material | monocentric | Olaia Naveiras | CHUV - Hématologie |
CHUV, Lausanne |
Commission cantonale d'Éthique de la Recherche sur l'être humain Vaud (CER-VD) | 28.10.2025 | |||||||
| 2025-02085 | Genotypic/Phenotypic Profiling and Immunosuppressant-Related Clinical Event Incidence in Hematological Patients Post Bone Marrow Transplantation. | personal data/biological material | monocentric | Prof. Caroline Samer | Geneva University Hospital |
Geneva University Hospitals, Geneva |
Commission Cantonale d'éthique de la recherche Genève (CCER) | 18.11.2025 | |||||||
| 2025-02080 | Long-term effectiveness of apical surgery using two materials for retrograde root canal obturation: A 10-year retrospective study | non clinical, involving persons | monocentric | A | PD Dr. Clemens Raabe | Department of Oral Surgery and Stomatology |
Klinik für Oralchirurgie und Stomatologie, zmk Bern, Bern |
Kantonale Ethikkommission Bern | 02.12.2025 | ||||||
| 2025-02079 | Complication, clinical and radiological outcomes after reverse shoulder arthroplasty. A multicentric, retrospective and comparative study | personal data/biological material | monocentric | Dr.med. David Hollo | Cantonal Hospital Aarau AG |
Cantonal Hospital Aarau AG, Aarau |
Ethikkommission Nordwest- und Zentralschweiz EKNZ | 04.12.2025 | |||||||