| BASEC ID | Project title | Type of project | Type of clinical trial | Study phase (clinical trials only) | multi- / monocentric | Category | Principal investigator | Sponsor | Investigational sites | Lead EC | Local EC(s) | Approval date | Minors | Study Ended | |
|---|---|---|---|---|---|---|---|---|---|---|---|---|---|---|---|
| 2024-02483 | TRI0385 - Evaluation of pathway inhibitors in fresh biopsies, cell lines and mouse xenografts from human breast cancer tumors | personal data/biological material | monocentric | Michael Rugaard Jensen, PhD | Novartis Pharma AG - Biomedical Research |
Novartis Pharma AG - Biomedical Research, Basel |
Ethikkommission Nordwest- und Zentralschweiz EKNZ | 12.12.2024 | |||||||
| 2024-02477 | Swiss REal World Registry for first line combination treatment of Enfortumab VEdotin And PembroLizumab in metastatic urothelial cancer- REVEAL | personal data/biological material | multicentric | Dr. med. Stefanie Fischer | Kantonsspital St. Gallen |
Klinik für Medizinische Onkologie und Hämatologie, Kantonsspital St. Gallen, St. Gallen Medizinische Onkologie, Inselspital Bern, Bern Onkologie und Hämatologie, Kantonsspital Baden, Baden Onkologie, More ... |
Ethikkommission Ostschweiz (EKOS) | Ethikkommission Nordwest- und Zentralschweiz EKNZ, Kantonale Ethikkommission Bern, Kantonale Ethikkommission Zürich, Commission Cantonale d'éthique de la recherche Genève (CCER) | 16.01.2025 | ||||||
| 2024-02473 | Extensor Triple-Flap Integrated Tenolysis; a retrospective 17 patients case series | personal data/biological material | monocentric | PD Dr. Med. Thomas Giesen |
Praxis of PD Dr. Med. Thomas Giesen (SOS Mano), Manno |
Comitato etico cantonale Ticino | 20.01.2025 | ||||||||
| 2024-02459 | Real World Data Insights: Comparing Clinical and Urodynamic Outcomes in Neurogenic Detrusor Overactivity Treatment with 200 U BoNT-A versus 300 U and 300 U versus 400 U BoNT-A | personal data/biological material | monocentric | PD Dr. med. M. Hund-Georgiadis | REHAB Basel |
REHAB Basel, Basel |
Ethikkommission Nordwest- und Zentralschweiz EKNZ | 17.12.2024 | |||||||
| 2024-02458 | Sensorimotor mismatch responses in freely moving humans - combining virtual reality and EEG recordings | non clinical, involving persons | monocentric | A | Dr Georg Keller | Friedrich Miescher Institute for Biomedical Research |
Friedrich Miescher Institute for Biomedical Research (FMI), Basel |
Ethikkommission Nordwest- und Zentralschweiz EKNZ | 20.01.2025 | ||||||
| 2024-02456 | A pilot study to develop personalised methods to quantify macronutrient intake and consumption | non clinical, involving persons | monocentric | A | Fabien Rebeaud | Liom Health AG |
Liom Health AG, Pfaeffikon SZ |
Ethikkommission Nordwest- und Zentralschweiz EKNZ | 23.12.2024 | ||||||
| 2024-02455 | Branch pulmonary artery reconstruction with the bovine jugular vein Contegra® patch | personal data/biological material | monocentric | Prof. Dr. med. Hitendu Dave | Kinderspital Zürich |
Universitäts- Kinderspital Zürich – Eleonorenstiftung, Zürich |
Kantonale Ethikkommission Zürich | 17.01.2025 | |||||||
| 2024-02447 | Evaluation of a clinical respiratory muscle strength training program and estimation of training improvements in persons with spinal cord injury | personal data/biological material | monocentric | Dr. Gabi Mueller | Swiss Paraplegic Research |
Swiss Paraplegic Research, Nottwil |
Ethikkommission Nordwest- und Zentralschweiz EKNZ | 18.12.2024 | |||||||
| 2024-02438 | Retrospective international multicenter study comparing polyurethan versus non-polyurethan covered implants in immediate prepectoral implant-based breast reconstruction in the setting of postmastectom More ... | personal data/biological material | monocentric | Prof. Dr. Walter Weber | Universitätsspital Basel (USB) |
Universitätsspital Basel, Basel |
Ethikkommission Nordwest- und Zentralschweiz EKNZ | 14.01.2025 | |||||||
| 2024-02434 | Hyponatremia in severe hypothyroidism (“The HYPO2 study”) | personal data/biological material | monocentric | Dr. Julia Beck | University Hospital Basel |
University Hospital Basel, Department of Endocrinology, Diabetes and Metabolism, Basel |
Ethikkommission Nordwest- und Zentralschweiz EKNZ | 10.01.2025 | |||||||
| 2024-02433 | Validation of the PAncreatic Surgery Composite Endpoint (PACE) | personal data/biological material | monocentric | Christoph Kümmerli | Clarunis University Digestive Health Care Center Basel |
Clarunis Digestive Health Care Center, Basel |
Ethikkommission Nordwest- und Zentralschweiz EKNZ | 12.12.2024 | |||||||
| 2024-02432 |
SAKK 16/xx_gender Sex specific differences in safety and efficacy outcomes in operable Stage III Non-Small Cell Lung Cancer Retrospective analysis of the trials SAKK 16/96, 16/00, 16/01, 16/08 and More ... |
personal data/biological material | monocentric | PD Dr. med. Sabine Schmid | SAKK |
Inselspital, Bern |
Kantonale Ethikkommission Bern | 07.01.2025 | |||||||
| 2024-02427 | Enhanced Vision and Imaging Test for Enabling Treatment Trials in Early and Intermediate AMD | non clinical, involving persons | monocentric | A | PD Dr. med. Maximilian Pfau | Eye Clinic, University Hospital Basel |
Eye Clinic, University Hospital Basel, Basel |
Ethikkommission Nordwest- und Zentralschweiz EKNZ | 08.01.2025 | ||||||
| 2024-02422 | Endoscopic submucosal dissection for colorectal lesions: outcomes in a Swiss communitiy hospital | personal data/biological material | monocentric | Prof. Dr. med. Radu Tutuian | Bürgerspital Solothurn |
Bürgerspital Solothurn, Solothurn |
Ethikkommission Nordwest- und Zentralschweiz EKNZ | 19.12.2024 | |||||||
| 2024-02417 | Reduce tobacco use in people living with HIV in Switzerland: A pragmatic randomized trial within the Swiss HIV Cohort Study | clinical trial | other clinical trials | monocentric | A | Dr. Marcel Stoeckle | University Hospital Basel |
University Hospital Basel, Basel |
Ethikkommission Nordwest- und Zentralschweiz EKNZ | 08.01.2025 | |||||
| 2024-02408 | Towards a smarter management for patients admitted with community-acquired pneumonia: a national multicenter observational study | personal data/biological material | monocentric | Dr Thomas Brahier | CHUV |
CHUV, Lausanne |
Commission cantonale d'Éthique de la Recherche sur l'être humain Vaud (CER-VD) | 16.01.2025 | |||||||
| 2024-02405 | Efficacy and Safety of MiLEP: Focus on Urethral Stricture and Continence Outcomes | non clinical, involving persons | monocentric | A | Dr. med. univ. Patrick Rein | Praxis für Urologie |
Praxis für Urologie Heerbrugg, 9435 Heerbrugg |
Ethikkommission Ostschweiz (EKOS) | 16.01.2025 | ||||||
| 2024-02396 |
Estimating the Underdiagnosis Rate of Idiopathic Normal Pressure Hydrocephalus in Patients with Cognitive Impairment: A Retrospective Analysis Using the NPH Radscale |
personal data/biological material | monocentric | Dr. Florian Ebel | Universität Basel Neurochirurgie |
USB Neurochirurgie, Basel |
Ethikkommission Nordwest- und Zentralschweiz EKNZ | 23.12.2024 | |||||||
| 2024-02394 | Évaluation de la fonction d'équilibre chez une population adulte et pédiatrique souffrant de déficits vestibulaires | non clinical, involving persons | monocentric | A | PD Dr Nils Guinand | HUG-CURIC Service ORL |
HUG-CURIC Service ORL, Genève |
Commission Cantonale d'éthique de la recherche Genève (CCER) | 20.01.2025 | yes | |||||
| 2024-02387 | Difficult airway during general anaesthesia: a mixed-methods retrospective observational trial | personal data/biological material | monocentric | PD Dr. med. Alexander Fuchs | Inselspital Bern |
Department of Anesthesiology and Pain Medicine, Inselspital Bern, Bern |
Kantonale Ethikkommission Bern | 20.12.2024 | |||||||