| BASEC ID | Project title | Type of project | Type of clinical trial | Study phase (clinical trials only) | multi- / monocentric | Category | Principal investigator | Sponsor | Investigational sites | Lead EC | Local EC(s) | Approval date | Minors | Study Ended | |
|---|---|---|---|---|---|---|---|---|---|---|---|---|---|---|---|
| 2019-01171 | The impact of patient age on postoperative outcomes, treatment costs, and long-term outcomes following pancreatic surgery | personal data/biological material | monocentric | Prof. Dr. Beat Gloor | Inselspital Bern University Clinic for Visceral Surgery und Medicin |
Inselspital Bern, University Clinic for Visceral Surgery und Medicin Bern, Bern |
Kantonale Ethikkommission Bern | 07.08.2019 | |||||||
| 2019-01170 | Specialised Paediatric PAlliativE CaRe: Assessing family, healthcare professionals and health system outcomes in a multi-site context of various care settings (SPhAERA) | non clinical, involving persons | multicentric | A | Dr. sc. med. Karin Zimmermann | University-Children's Hospital Zurich |
University-Children's Hospital Zurich, Zurich Inselspital Bern University Hospital, Department of Pediatrics, Bern Children's Hospital Aarau, Aarau University Children's Hospital Basel, Basel |
Kantonale Ethikkommission Zürich | Ethikkommission Nordwest- und Zentralschweiz EKNZ, Kantonale Ethikkommission Bern | 10.10.2019 | yes | ||||
| 2019-01169 | Clinical and immunological patterns of non-infectious aortic graft inflammation in bovine vs non-biological grafts | non clinical, involving persons | monocentric | A | Prof. Dr. med. Dr. h.c. Thierry Carrel | Insel Group AG, Dept. of Cardiovascular Surgery, University Hospital Bern |
Dept. of Cardiovascular Surgery, Bern |
Kantonale Ethikkommission Bern | 30.07.2019 | Study has ended | |||||
| 2019-01167 | Prevalence of hyperkalemia and other electrolyte disorders in patients with acute kidney injury in the emergency department – a retrospective study | personal data/biological material | monocentric | PD Dr. med. univ. Gregor Lindner | Bürgerspital Solothurn |
Bürgerspital Solothurn, Solothurn |
Ethikkommission Nordwest- und Zentralschweiz EKNZ | 11.07.2019 | Study has ended | ||||||
| 2019-01166 | A single center, randomized control study to compare efficacy and safety of femto-laser created clear corneal incisions with manually created clear corneal incisions during cataract surgery | clinical trial | medical devices | monocentric | A1 | Prof. Dr. med. Bojan Pajic | Ziemer Ophthalmic Systems AG |
Augenzentrum ORASIS AG, Reinach |
Ethikkommission Nordwest- und Zentralschweiz EKNZ | 26.08.2019 | |||||
| 2019-01165 | Studying human immune cell phenotypes and trafficking from periphery across the human brain barriers into CNS tissue in CNS autoimmunity - A monocentric longitudinal observational study | non clinical, involving persons | monocentric | A | Dr.med. Anke Salmen | Universitätsklinik für Neurologie, Inselspital Bern |
Universitätsklinik für Neurologie, Bern |
Kantonale Ethikkommission Bern | 01.10.2019 | ||||||
| 2019-01164 | Analysis of the tumor microenvironment in tumors located in the central nervous system. | personal data/biological material | monocentric | Dr Valérie Dutoit | University of Geneva |
University of Geneva, Geneva |
Commission Cantonale d'éthique de la recherche Genève (CCER) | 06.08.2019 | Study has ended | ||||||
| 2019-01163 | Clinical and radiographic outcomes following non-surgical mechanical therapy of peri-implantitis with or without adjunctive diode laser application: A 12-month double-blinded randomized clinical trial | clinical trial | medical devices | monocentric | A1 | Prof. Giovanni Salvi | University of Bern |
Department of Periodontology, University of Bern, Bern |
Kantonale Ethikkommission Bern | 06.11.2019 | Study has ended | ||||
| 2019-01162 |
PROPHETIC Studie Prognostication of Outcome in Patients with Out-of Hospital Cardiac Arrest Hospitalized in Intensive Care |
non clinical, involving persons | multicentric | A | Prof. Sabina Hunziker | University Hospital Basel |
Universitätsspital Basel, Basel Kantonsspital Aarau, Aarau |
Ethikkommission Nordwest- und Zentralschweiz EKNZ | Ethikkommission Nordwest- und Zentralschweiz EKNZ | 07.10.2019 | |||||
| 2019-01161 | FEASIBILITY OF AN INTERACTIVE TABLET-BASED EXERCISE PROGRAM FOR PEOPLE WITH CHRONICAL DISEASES | clinical trial | other clinical trials | monocentric | A | Mr. Damiano Zemp | EOC |
EOC, Mendrisio |
Comitato etico cantonale Ticino | 16.08.2019 | Study has ended | ||||
| 2019-01160 |
Whole-brain irradiation with hippocampal sparing and dose escalation on metastases: neurocognitive testing and biological imaging A phase II prospective randomized multicentre study |
clinical trial | other clinical trials | multicentric | B | Prof. Dr. med. Matthias Guckenberger | Klinik für Radio-Onkologie |
UniversitätsSpital Zürich, Zürich Klinik Hirslanden, 8032 Zürich |
Kantonale Ethikkommission Zürich | Kantonale Ethikkommission Zürich | 04.11.2019 | Study has ended | |||
| 2019-01158 | The effect of Comorbidity on Outcome in Patients Hospitalized For Acute Heart Failure in Lausanne (LAU-AHF) | personal data/biological material | monocentric | Professor Dr. Roger Hullin | CHUV - BU44-2208 |
Centre Hospitalier Universitaire Vaudois, Lausanne |
Commission cantonale d'Éthique de la Recherche sur l'être humain Vaud (CER-VD) | 18.07.2019 | Study has ended | ||||||
| 2019-01157 |
CNIS793X2101 - A phase I/Ib, open-label, multi-center dose escalation study of NIS793 in combination with PDR001 in adult patients with advanced malignancies |
clinical trial | drugs | phase 1 | monocentric | C | Prof. Dr. med. Markus Jörger | Novartis Pharma Schweiz AG |
Kantonsspital, St. Gallen |
Ethikkommission Ostschweiz (EKOS) | 09.08.2019 | Study has ended | |||
| 2019-01156 | Urgent large bowel decompression: is Caecostomy a valid alternative to loop colostomy? | personal data/biological material | monocentric | Dr. Michele Arigoni | Ospedale Reginale di Locarno |
Ospedale Regionale di Locarno, Locarno |
Comitato etico cantonale Ticino | 09.07.2019 | |||||||
| 2019-01155 | Bacterial infections in patients with cirrhosis: Impact of an antibiotic stewardship program on in-hospital stay and mortality | personal data/biological material | monocentric | Prof. Annalisa Berzigotti | UVCM Hepatologie |
UVCM Hepatologie, Bern |
Kantonale Ethikkommission Bern | 19.12.2019 | Study has ended | ||||||
| 2019-01154 | 3D primary cell culture as a new model for precision medicine in gastro-entero-pancreatic neuroendocrine neoplasms (GEP-NEN) | personal data/biological material | multicentric | Prof. Aurel Perren | Institut für Pathologie, Universität Bern |
Institut für Pathologie, Universität Bern, Bern University of Basel, Basel HÔPITAUX UNIVERSITAIRES GENÈVE, Geneva CHUV, Lausanne University Hospital Zurich, Zurich |
Kantonale Ethikkommission Bern | Ethikkommission Nordwest- und Zentralschweiz EKNZ, Kantonale Ethikkommission Zürich, Commission cantonale d'Éthique de la Recherche sur l'être humain Vaud (CER-VD), Commission Cantonale d'éthique de l More ... | 02.12.2019 | ||||||
| 2019-01153 | Human Pegivirus and immune response after allogeneic stem cell transplantation: other than a commensal virus? | personal data/biological material | monocentric | Dr Diem-Lan Vu Cantero | Service of infectious diseases |
Geneva University Hospitals, Geneva |
Commission Cantonale d'éthique de la recherche Genève (CCER) | 09.07.2019 | |||||||
| 2019-01152 | TRI0209 – Single-cell dissection of the cellular ecosystem in hepatocellular carcinoma | personal data/biological material | monocentric | Dr Guglielmo Roma | Novartis Pharma AG - NIBR |
Novartis Pharma AG - NIBR, Basel |
Ethikkommission Nordwest- und Zentralschweiz EKNZ | 07.08.2019 | |||||||
| 2019-01151 | Patientenselektion und Langzeitverlauf bei Patienten mit einer Pace & Ablate Strategie zur interventionellen Frequenzkontrolle bei symptomatischem permanenten Vorhofflimmern – eine retrospektive multi More ... | personal data/biological material | multicentric | Dr. med. Nikola Kozhuharov | Universitätsklinik für Kardiologie, Inselspital |
Universitätsklinik für Kardiologie, Inselspital, Bern Universitätsspital Basel, Kardiologie, Basel Universitätsspital Genf, Genf |
Kantonale Ethikkommission Bern | Ethikkommission Nordwest- und Zentralschweiz EKNZ, Commission Cantonale d'éthique de la recherche Genève (CCER) | 11.09.2019 | ||||||
| 2019-01150 |
DANTE FLOT8 - A randomized, open-label Phase II/III efficacy and safety study of atezolizumab in combination with FLOT versus FLOT alone in patients with gastric cancer and adenocarcinoma of the oeso More ... |
clinical trial | drugs | phase 3 | multicentric | B | Dr. med. Alexander Siebenhüner | Institut für Klinische Krebsforschung IKF GmbH |
Klinik für Hämatologie und Onkologie Hirslanden Zürich AG, Zürich Spital STS AG, Thun Inselspital, Bern Kantonsspital Baden, Brugg und Baden Kantonsspital Olten, Olten St. Claraspital, Basel Tumor Zen More ... |
Kantonale Ethikkommission Zürich | Ethikkommission Nordwest- und Zentralschweiz EKNZ, Ethikkommission Ostschweiz (EKOS), Kantonale Ethikkommission Bern, Kantonale Ethikkommission Zürich, Commission cantonale d'Éthique de la Recherche s More ... | 19.12.2019 | |||