| BASEC ID | Project title | Type of project | Type of clinical trial | Study phase (clinical trials only) | multi- / monocentric | Category | Principal investigator | Sponsor | Investigational sites | Lead EC | Local EC(s) | Approval date | Minors | Study Ended | |
|---|---|---|---|---|---|---|---|---|---|---|---|---|---|---|---|
| 2021-D0074 | Prospective evaluation of the Laryngeal Mask Singularity® in adult patients under clinical conditions | clinical trial | medical devices | monocentric | A1 | PD Dr. Alexander Dullenkopf | Spital Thurgau Frauenfeld |
Spital Thurgau, Frauenfeld |
Ethikkommission Ostschweiz (EKOS) | 10.12.2021 | |||||
| 2021-D0072 | A Phase 3 (Pivotal Stage) Study of NBTXR3 Activated by Investigator’s Choice of Radiotherapy Alone or Radiotherapy in Combination with Cetuximab for Platinum-based Chemotherapy-ineligible Elderly Pati More ... | clinical trial | medical devices | multicentric | C1 | PD Dr. Laurent Muller | NANOBIOTIX S.A. |
Universitätsspital Basel, Basel Inselspital, Universitätsspital Bern, Bern |
Ethikkommission Nordwest- und Zentralschweiz EKNZ | Kantonale Ethikkommission Bern | 05.05.2022 | ||||
| 2021-D0071 | Single-center prospective clinical trial to validate the performance of the Aktiia optical blood pressure monitoring (OBPM) device at the wrist against double auscultation | clinical trial | medical devices | monocentric | C2 | Dr. Grégoire Wuerzner | Aktiia SA |
CHUV, Lausanne |
Commission cantonale d'Éthique de la Recherche sur l'être humain Vaud (CER-VD) | 10.01.2022 | |||||
| 2021-D0070 | Prospective Post-Market Clinical Follow-Up (PMCF) Study to Investigate the Clinical Outcomes of a Premium Monofocal Intraocular lens (IOL) in Comparison to an EDOF Lens | clinical trial | medical devices | monocentric | A1 | Dr. med. Kristof Vandekerckhove | PhysIOL sa/nv |
Centre oculaire Vista Alpina, Sierre |
Commission cantonale d'Éthique de la Recherche sur l'être humain Vaud (CER-VD) | 02.02.2022 | |||||
| 2021-D0068 | Intra-observer variability in the assessment of cervical stiffness with the Pregnolia System | clinical trial | medical devices | monocentric | A1 | Dr. med. Gundula Hebisch | Pregnolia AG |
Kantonsspital Frauenfeld, Frauenfeld |
Ethikkommission Ostschweiz (EKOS) | 21.12.2021 | |||||
| 2021-D0067 | Repetitive Transcranial Magnetic Stimulation (rTMS) for the treatment of affective symptoms in patients suffering from dementia: a randomised clinical trial | clinical trial | medical devices | monocentric | A1 | Pr Armin von Gunten | CHUV |
CHUV, Lausanne |
Commission cantonale d'Éthique de la Recherche sur l'être humain Vaud (CER-VD) | 27.01.2022 | |||||
| 2021-D0066 | Pilot study on response assessment during MR-guided radiation therapy for glioblastoma multiforme | clinical trial | medical devices | monocentric | A1 | Prof. Dr. Nicolaus Andratschke | Universitätsspital Zürich |
University Hospital of Zurich, Zurich |
Kantonale Ethikkommission Zürich | 18.01.2022 | |||||
| 2021-D0065 | Blink restoration in patients with facial nerve palsy (NEURO-BLINK) | clinical trial | medical devices | monocentric | C2 | Dr. med. Anthia Papazoglou | Cantonal Hospital Aarau |
Cantonal Hospital Aarau, Aarau |
Ethikkommission Nordwest- und Zentralschweiz EKNZ | 20.01.2022 | |||||
| 2021-D0064 | Evaluation of novel and adapted MR spectroscopy and metabolic imaging techniques for non-invasive monitoring of metabolite levels in humans in physiologic states of everyday life | clinical trial | medical devices | monocentric | C2 | Prof Roland Kreis | Inselgruppe AG |
University Bern, Bern |
Kantonale Ethikkommission Bern | 17.01.2022 | |||||
| 2021-D0062 | Comparison of the effectiveness of brightening cream vs laser therapy (QS Nd:YAG 1064nm laser) in skin hyperpigmentation after sclerotherapy by objective measurement: A randomized controlled monocent More ... | clinical trial | combination drugs/devices | monocentric | A1 | Dr.med. Kristine Heidemeyer | Dermatologie Inselspital |
Dermatologie Inselspital, Bern |
Kantonale Ethikkommission Bern | 10.01.2022 | |||||
| 2021-D0061 | Temporary push-on rings of antimicrobial alloys for transmucosal implant abutment systems: a randomized clinical study on early and mature biofilm formation | clinical trial | medical devices | monocentric | A1 | Dr. med. dent. Lucia K. Zaugg | UZB |
UZB, Department for Reconstructive Dentistry, Basel |
Ethikkommission Nordwest- und Zentralschweiz EKNZ | 15.12.2021 | |||||
| 2021-D0060 | A randomized trial of ultrasound-facilitated, catheter-directed, thrombolysis versus anticoagulation for acute intermediate-high risk pulmonary embolism: The higher-risk pulmonary embolism thrombolysi More ... | clinical trial | medical devices | multicentric | A1 | Professor Nils Kucher | Boston Scientific International SA |
University Hospital of Zurich, Zurich Universitätsspital Basel, Universitätsspital Basel Kardiologie Petersgrabe CHUV, CHUV, Bugnon 46, 1011 Lausanne, Suisse |
Kantonale Ethikkommission Zürich | Commission cantonale d'Éthique de la Recherche sur l'être humain Vaud (CER-VD), Ethikkommission Nordwest- und Zentralschweiz EKNZ | 15.03.2022 | ||||
| 2021-D0058 | Immediate implant placement in molar extraction sockets using fully tapered tissue level implants: a randomized controlled post-market clinical study in Germany, Hong Kong and Switzerland | clinical trial | medical devices | monocentric | A1 | Prof.Dr.med.dent. Ronald E. Jung | Institut Straumann AG |
University of Zurich, Center of Dental Medicine, Clinic of Reconstructive Dentistry, Zurich |
Kantonale Ethikkommission Zürich | 26.11.2021 | |||||
| 2021-D0056 | Comparison between transcranial and direct cortical stimulation of motor evoked potentials during the resection of supratentorial brain tumors in terms of prognostic accuracy for postoperative motor d More ... | clinical trial | medical devices | monocentric | A1 | PD Dr. med. Kathleen Seidel | Universitätsmedizin Göttingen |
Department of Neurosurgery, Bern |
Kantonale Ethikkommission Bern | 09.03.2022 | |||||
| 2021-D0055 | Improvement of memory in Mild Cognitive Impairment (MCI) using transcranial alternating current stimulation (tACS) guided by EEG and MRI: a randomized, sham-controlled, parallel-arm, double-blind stud More ... | clinical trial | medical devices | monocentric | C2 | Prof. Christoph Michel | University of Geneva |
University of Geneva, Geneva |
Commission Cantonale d'éthique de la recherche Genève (CCER) | 02.02.2022 | |||||
| 2021-D0053 | Feasibility and validity of robotic assessments with the ReHapticKnob to characterize kinaesthesia and haptic perception of the hand in patients with Parkinson’s disease: an exploratory study | clinical trial | medical devices | monocentric | C2 | Dr. med. Daria Dinacci | Rehabilitation Engineering Lab, ETH Zurich |
Clinica Hildebrand Centro di riabilitazione Brissago, Brissago |
Comitato etico cantonale Ticino | 06.12.2021 | |||||
| 2021-D0052 | The Possible Influence of Different Follow-up Modalities on Overall Survival in Ovarian Cancer: A Multicenter Observational Cohort Study | clinical trial | medical devices | multicentric | A1 | Prof. Dr. med. Pius Wyss | Stiftung Swiss Tumor Institute |
IMZ Zürich, Zürich Praxis im Frauenzentrum, Bern Spital Zollikerberg, Trichtenhauserstrasse 20 Praxis für Gyäkologie und Geburtshilfe, Stockerstrasse 42 Spital Limmattal, Urdorferstrasse 100 |
Kantonale Ethikkommission Zürich | Kantonale Ethikkommission Bern, Kantonale Ethikkommission Zürich | 30.11.2021 | ||||
| 2021-D0051 | HER2-directed Biosimilar OgivriTM in Breast Cancer: Real world Observational trial for the description of Quality of Life and Outcome using ePRO (OGIPRO- Trial) | clinical trial | medical devices | multicentric | A1 | Prof. Andreas Trojan | Mobile Health AG |
Onko Zentrum Zürich, Zürich Spitalzentrum Oberwallis (SZO), Brig Tumorcenter Hirslanden, Rain 34 Tumorzentrum ZeTuP Rapperswil-Jona, Alte Jonastrasse 24 Tumor- und Brustzentrum ZeTuP St.Gallen, Rorsch More ... |
Kantonale Ethikkommission Zürich | Commission cantonale d'Éthique de la Recherche sur l'être humain Vaud (CER-VD), Kantonale Ethikkommission Bern, Ethikkommission Ostschweiz (EKOS), Kantonale Ethikkommission Zürich, Ethikkommission Nor More ... | 03.12.2021 | ||||
| 2021-D0050 |
Leadless AV versus DDD pacing study (LEAVE DDD trial) A randomized controlled single-center trial on leadless versus conventional cardiac dual-chamber pacing |
clinical trial | medical devices | monocentric | A1 | PD Dr. Dr. Andreas Haeberlin | Bern University Hospital |
Bern University Hospital, Bern |
Kantonale Ethikkommission Bern | 25.01.2022 | |||||
| 2021-D0049 |
Treatment of Scapular Dyskinesis with Electrical Myostimulation Behandlung einer Schulterblattfehlhaltung mittels oberflächlicher elektrischer Muskelstimulation |
clinical trial | medical devices | monocentric | A1 | Dr. med. Michael Schär | Klinik für Orthopädie und Traumatologie, Inselspital, Bern |
Klinik für Orthopädie und Traumatologie, Inselspital, Bern |
Kantonale Ethikkommission Bern | 20.04.2022 | |||||