BASEC ID Project title Type of project Type of clinical trial Study phase (clinical trials only) multi- / monocentric Category Principal investigator Sponsor Investigational sites Lead EC Local EC(s) Approval date Minors Study Ended
2021-D0074 Prospective evaluation of the Laryngeal Mask Singularity® in adult patients under clinical conditions clinical trial medical devices monocentric A1 PD Dr. Alexander Dullenkopf Spital Thurgau Frauenfeld Spital Thurgau, Frauenfeld
Ethikkommission Ostschweiz (EKOS) 10.12.2021
2021-D0072 A Phase 3 (Pivotal Stage) Study of NBTXR3 Activated by Investigator’s Choice of Radiotherapy Alone or Radiotherapy in Combination with Cetuximab for Platinum-based Chemotherapy-ineligible Elderly Pati More ... clinical trial medical devices multicentric C1 PD Dr. Laurent Muller NANOBIOTIX S.A. Universitätsspital Basel, Basel
Inselspital, Universitätsspital Bern, Bern
Ethikkommission Nordwest- und Zentralschweiz EKNZ Kantonale Ethikkommission Bern 05.05.2022
2021-D0071 Single-center prospective clinical trial to validate the performance of the Aktiia optical blood pressure monitoring (OBPM) device at the wrist against double auscultation clinical trial medical devices monocentric C2 Dr. Grégoire Wuerzner Aktiia SA CHUV, Lausanne
Commission cantonale d'Éthique de la Recherche sur l'être humain Vaud (CER-VD) 10.01.2022
2021-D0070 Prospective Post-Market Clinical Follow-Up (PMCF) Study to Investigate the Clinical Outcomes of a Premium Monofocal Intraocular lens (IOL) in Comparison to an EDOF Lens clinical trial medical devices monocentric A1 Dr. med. Kristof Vandekerckhove PhysIOL sa/nv Centre oculaire Vista Alpina, Sierre
Commission cantonale d'Éthique de la Recherche sur l'être humain Vaud (CER-VD) 02.02.2022
2021-D0068 Intra-observer variability in the assessment of cervical stiffness with the Pregnolia System clinical trial medical devices monocentric A1 Dr. med. Gundula Hebisch Pregnolia AG Kantonsspital Frauenfeld, Frauenfeld
Ethikkommission Ostschweiz (EKOS) 21.12.2021
2021-D0067 Repetitive Transcranial Magnetic Stimulation (rTMS) for the treatment of affective symptoms in patients suffering from dementia: a randomised clinical trial clinical trial medical devices monocentric A1 Pr Armin von Gunten CHUV CHUV, Lausanne
Commission cantonale d'Éthique de la Recherche sur l'être humain Vaud (CER-VD) 27.01.2022
2021-D0066 Pilot study on response assessment during MR-guided radiation therapy for glioblastoma multiforme clinical trial medical devices monocentric A1 Prof. Dr. Nicolaus Andratschke Universitätsspital Zürich University Hospital of Zurich, Zurich
Kantonale Ethikkommission Zürich 18.01.2022
2021-D0065 Blink restoration in patients with facial nerve palsy (NEURO-BLINK) clinical trial medical devices monocentric C2 Dr. med. Anthia Papazoglou Cantonal Hospital Aarau Cantonal Hospital Aarau, Aarau
Ethikkommission Nordwest- und Zentralschweiz EKNZ 20.01.2022
2021-D0064 Evaluation of novel and adapted MR spectroscopy and metabolic imaging techniques for non-invasive monitoring of metabolite levels in humans in physiologic states of everyday life clinical trial medical devices monocentric C2 Prof Roland Kreis Inselgruppe AG University Bern, Bern
Kantonale Ethikkommission Bern 17.01.2022
2021-D0062 Comparison of the effectiveness of brightening cream vs laser therapy (QS Nd:YAG 1064nm laser) in skin hyperpigmentation after sclerotherapy by objective measurement: A randomized controlled monocent More ... clinical trial combination drugs/devices monocentric A1 Dr.med. Kristine Heidemeyer Dermatologie Inselspital Dermatologie Inselspital, Bern
Kantonale Ethikkommission Bern 10.01.2022
2021-D0061 Temporary push-on rings of antimicrobial alloys for transmucosal implant abutment systems: a randomized clinical study on early and mature biofilm formation clinical trial medical devices monocentric A1 Dr. med. dent. Lucia K. Zaugg UZB UZB, Department for Reconstructive Dentistry, Basel
Ethikkommission Nordwest- und Zentralschweiz EKNZ 15.12.2021
2021-D0060 A randomized trial of ultrasound-facilitated, catheter-directed, thrombolysis versus anticoagulation for acute intermediate-high risk pulmonary embolism: The higher-risk pulmonary embolism thrombolysi More ... clinical trial medical devices multicentric A1 Professor Nils Kucher Boston Scientific International SA University Hospital of Zurich, Zurich
Universitätsspital Basel, Universitätsspital Basel
Kardiologie
Petersgrabe
CHUV, CHUV, Bugnon 46, 1011 Lausanne, Suisse
Kantonale Ethikkommission Zürich Commission cantonale d'Éthique de la Recherche sur l'être humain Vaud (CER-VD), Ethikkommission Nordwest- und Zentralschweiz EKNZ 15.03.2022
2021-D0058 Immediate implant placement in molar extraction sockets using fully tapered tissue level implants: a randomized controlled post-market clinical study in Germany, Hong Kong and Switzerland clinical trial medical devices monocentric A1 Prof.Dr.med.dent. Ronald E. Jung Institut Straumann AG University of Zurich, Center of Dental Medicine, Clinic of Reconstructive Dentistry, Zurich
Kantonale Ethikkommission Zürich 26.11.2021
2021-D0056 Comparison between transcranial and direct cortical stimulation of motor evoked potentials during the resection of supratentorial brain tumors in terms of prognostic accuracy for postoperative motor d More ... clinical trial medical devices monocentric A1 PD Dr. med. Kathleen Seidel Universitätsmedizin Göttingen Department of Neurosurgery, Bern
Kantonale Ethikkommission Bern 09.03.2022
2021-D0055 Improvement of memory in Mild Cognitive Impairment (MCI) using transcranial alternating current stimulation (tACS) guided by EEG and MRI: a randomized, sham-controlled, parallel-arm, double-blind stud More ... clinical trial medical devices monocentric C2 Prof. Christoph Michel University of Geneva University of Geneva, Geneva
Commission Cantonale d'éthique de la recherche Genève (CCER) 02.02.2022
2021-D0053 Feasibility and validity of robotic assessments with the ReHapticKnob to characterize kinaesthesia and haptic perception of the hand in patients with Parkinson’s disease: an exploratory study clinical trial medical devices monocentric C2 Dr. med. Daria Dinacci Rehabilitation Engineering Lab, ETH Zurich Clinica Hildebrand Centro di riabilitazione Brissago, Brissago
Comitato etico cantonale Ticino 06.12.2021
2021-D0052 The Possible Influence of Different Follow-up Modalities on Overall Survival in Ovarian Cancer: A Multicenter Observational Cohort Study clinical trial medical devices multicentric A1 Prof. Dr. med. Pius Wyss Stiftung Swiss Tumor Institute IMZ Zürich, Zürich
Praxis im Frauenzentrum, Bern
Spital Zollikerberg, Trichtenhauserstrasse 20
Praxis für Gyäkologie und Geburtshilfe, Stockerstrasse 42
Spital Limmattal, Urdorferstrasse 100
Kantonale Ethikkommission Zürich Kantonale Ethikkommission Bern, Kantonale Ethikkommission Zürich 30.11.2021
2021-D0051 HER2-directed Biosimilar OgivriTM in Breast Cancer: Real world Observational trial for the description of Quality of Life and Outcome using ePRO (OGIPRO- Trial) clinical trial medical devices multicentric A1 Prof. Andreas Trojan Mobile Health AG Onko Zentrum Zürich, Zürich
Spitalzentrum Oberwallis (SZO), Brig
Tumorcenter Hirslanden, Rain 34
Tumorzentrum ZeTuP Rapperswil-Jona, Alte Jonastrasse 24
Tumor- und Brustzentrum ZeTuP St.Gallen, Rorsch More ...
Kantonale Ethikkommission Zürich Commission cantonale d'Éthique de la Recherche sur l'être humain Vaud (CER-VD), Kantonale Ethikkommission Bern, Ethikkommission Ostschweiz (EKOS), Kantonale Ethikkommission Zürich, Ethikkommission Nor More ... 03.12.2021
2021-D0050 Leadless AV versus DDD pacing study (LEAVE DDD trial)
A randomized controlled single-center trial on leadless versus conventional cardiac dual-chamber pacing
clinical trial medical devices monocentric A1 PD Dr. Dr. Andreas Haeberlin Bern University Hospital Bern University Hospital, Bern
Kantonale Ethikkommission Bern 25.01.2022
2021-D0049 Treatment of Scapular Dyskinesis with Electrical Myostimulation

Behandlung einer Schulterblattfehlhaltung mittels oberflächlicher elektrischer Muskelstimulation
clinical trial medical devices monocentric A1 Dr. med. Michael Schär Klinik für Orthopädie und Traumatologie, Inselspital, Bern Klinik für Orthopädie und Traumatologie, Inselspital, Bern
Kantonale Ethikkommission Bern 20.04.2022