| BASEC ID | Project title | Type of project | Type of clinical trial | Study phase (clinical trials only) | multi- / monocentric | Category | Principal investigator | Sponsor | Investigational sites | Lead EC | Local EC(s) | Approval date | Minors | Study Ended | |
|---|---|---|---|---|---|---|---|---|---|---|---|---|---|---|---|
| 2019-01883 |
CINC424G12201_A Phase II open-label, single-arm, multi-center study of ruxolitinib added to corticosteroids in pediatric subjects with moderate and severe chronic graft vs. host disease after allogen More ... |
clinical trial | drugs | phase 2 | monocentric | C | Prof. Dr. med Tayfun Güngör | Novartis Pharma Schweiz AG |
Kinderspital Zürich, Zürich |
Kantonale Ethikkommission Zürich | 21.01.2020 | yes | Study has ended | ||
| 2019-01882 | Does contact with the fingertip reduce postural variability in different cohorts? A comparison between children and adults | non clinical, involving persons | monocentric | A | PD. Dr. Oliver Faule | Universität Basel |
Universität Basel (DSBG), Basel |
Ethikkommission Nordwest- und Zentralschweiz EKNZ | 25.10.2019 | yes | |||||
| 2019-01881 | BIO|MASTER.BIOMONITOR III | clinical trial | medical devices | multicentric | A1 | Prof. PD Dr. med. Peter Ammann | BIOTRONIK SE & Co. KG |
Kantonsspital St. Gallen, St. Gallen Fondazione CardioCentro Ticino, Lugano Centre Hospitalier Universitaire Vaudois (CHUV), Lausanne |
Ethikkommission Ostschweiz (EKOS) | Commission cantonale d'Éthique de la Recherche sur l'être humain Vaud (CER-VD), Comitato etico cantonale Ticino | 29.10.2019 | Study has ended | |||
| 2019-01879 | Prospective observational study to explore pathophysiology associations between interstitial fibrosis and myocardial blood flow in heart transplant patients | non clinical, involving persons | monocentric | B | Professor Dr. Roger Hullin | CHUV - BU44_07_2208 |
CHUV, Lausanne |
Commission cantonale d'Éthique de la Recherche sur l'être humain Vaud (CER-VD) | 17.12.2019 | ||||||
| 2019-01878 |
Comparison of levetiracetam and phenobarbital as first-line treatment of neonatal seizures Vergleich der Verträglichkeit und Wirksamkeit von Levetiracetam vs. Phenobarbital als Primärbehandlung bei More ... |
personal data/biological material | monocentric | PD Dr. med. Dr. sc. Georgia Ramantani |
Neuropädiatrie, Universitäts-Kinderspital, Zürich |
Kantonale Ethikkommission Zürich | 04.11.2019 | ||||||||
| 2019-01877 | Study on endocrine dispruptor deposition in human adipose tissue and its association with metabolic dysfunction and genetic variants. | personal data/biological material | monocentric | Prof. Tony Fracasso | Centre Universitaire Romand de Médecine Légale - CHUV |
CURML, Lausanne |
Commission cantonale d'Éthique de la Recherche sur l'être humain Vaud (CER-VD) | 12.02.2020 | |||||||
| 2019-01876 | AGING HEART ZÜRICH – RETROSPECTIVE ANALYSIS | personal data/biological material | monocentric | PD Dr. med. Matthias Hermann | Universitätsspital Zürich |
Universitätsspital Zürich, Zürich |
Kantonale Ethikkommission Zürich | 15.01.2020 | |||||||
| 2019-01875 | Hotspot für Impfskeptiker – Charakteristika von Kindern mit unvollständigem Impfstatus in einer Kindernotfallstation in der Zentralschweiz | personal data/biological material | monocentric | Dr. Leopold Simma | Luzerner Kantonsspital |
LUKS, Luzern |
Ethikkommission Nordwest- und Zentralschweiz EKNZ | 30.10.2019 | Study has ended | ||||||
| 2019-01874 | Is a physiotherapy-led follow-up programme feasible in adult critical illness survivors after discharge home? A single-center trial | clinical trial | other clinical trials | monocentric | A | Natalie Ott | Institut für Therapien und Rehabilitation des Kantonsspital Winterthur |
Kantionsspital Winterthur, Winterthur |
Kantonale Ethikkommission Zürich | 21.11.2019 | Study has ended | ||||
| 2019-01873 | Towards development of neurofilament light chain as precision medicine biomarker for multiple sclerosis | personal data/biological material | monocentric | PD Dr Jens Kuhle | Unispital Basel |
Unispital Basel, Basel |
Ethikkommission Nordwest- und Zentralschweiz EKNZ | 09.10.2019 | |||||||
| 2019-01872 | SINGLE CELL HETEROGENEITY OF HUMAN ADIPOSE TISSUE. | non clinical, involving persons | monocentric | A | PD Dr. Irene Burger | Kantonsspital Baden |
Kantonsspital Baden, Baden |
Ethikkommission Nordwest- und Zentralschweiz EKNZ | 04.11.2019 | Study has ended | |||||
| 2019-01871 | HMGCR antibody positive necrotising myositis | personal data/biological material | monocentric | Prof. Peter Villiger | Universitätsklinik für RIA, Inselspital und Universität Bern |
Inselspital und Universität, Bern |
Kantonale Ethikkommission Bern | 19.05.2020 | |||||||
| 2019-01869 | A retrospective tissue analysis to assess the association between EB1 expression and C-MYC gene amplifications or rearrangements in diffuse large B-cell lymphoma tissue, and between EB1 expression and More ... | personal data/biological material | monocentric | Prof. Dr. med. Alexandar Tzankov | Basilea Pharmaceutica International Ltd. |
University Hospital Basel | Institute of Medical Genetics and Pathology, Basel |
Ethikkommission Nordwest- und Zentralschweiz EKNZ | 09.10.2019 | |||||||
| 2019-01867 | Randomised, double-blind, multi-centre, clinical trial to assess the safety and efficacy of SDX-3101, an innovative vibration therapy portable device for the treatment of chronic rhinosinusitis withou More ... | clinical trial | medical devices | multicentric | C | PD Dr. med. M. Soyka | SynDermix AG |
Universitätsspital Zürich, Zürich HNO Klinik Inselspital, 3010 Bern |
Kantonale Ethikkommission Zürich | Kantonale Ethikkommission Bern | 05.02.2020 | Study has ended | |||
| 2019-01865 | Lungenkrebs im Zeitalter der zielgerichteten Immuntherapien – eine retrospektive Auswertung der Daten von 2015 – 2018 des onkologischen Zentrums am Luzerner Kantonsspital (LUKS) | personal data/biological material | monocentric | Prof. Dr. med. Joachim Diebold | Chefarzt Pathologie |
Luzerner Kantonsspital, Luzern |
Ethikkommission Nordwest- und Zentralschweiz EKNZ | 07.11.2019 | |||||||
| 2019-01864 | Validité et fiabilité du test de marche de 6 minutes sur une distance de 6 mètres chez les personnes atteintes de sclérose en plaques | clinical trial | other clinical trials | monocentric | A | PhD Kenny Guex | Haute Ecole de Santé Vaud |
Haute Ecole de Santé Vaud, Lausanne |
Commission cantonale d'Éthique de la Recherche sur l'être humain Vaud (CER-VD) | 07.02.2020 | Study has ended | ||||
| 2019-01862 | Artificial Intelligence in oncological Imaging Network | personal data/biological material | monocentric | Prof. Dr. Christoph Stippich | NRA, USZ |
NRA, USZ, Zurich |
Kantonale Ethikkommission Zürich | 21.01.2020 | |||||||
| 2019-01861 | External validation of EPIC’s Readmission Risk model, the LACE+ index and SQLape as predictors of unplanned hospital readmissions: A monocentric, retrospective case-control study in Switzerland | personal data/biological material | monocentric | Aljoscha Benjamin Hwang | Luzerner Kantonsspital |
Luzerner Kantonsspital, Luzern |
Ethikkommission Nordwest- und Zentralschweiz EKNZ | 07.10.2019 | Study has ended | ||||||
| 2019-01860 | Clinical Impact of rapid identification of positive blood cultures vs. internal laboratory standard | personal data/biological material | monocentric | Dr Adrian Egli | University Hospital Basel |
Universitätsspital, Basel |
Ethikkommission Nordwest- und Zentralschweiz EKNZ | 25.10.2019 | |||||||
| 2019-01859 | A RANDOMIZED CLINICAL TRIAL OF ANDEXANET ALFA IN ACUTE INTRACRANIAL HEMORRHAGE IN PATIENTS RECEIVING AN ORAL FACTOR XA INHIBITOR | clinical trial | drugs | phase 4 | multicentric | C | Dr /David/ Seiffge | Alexion Pharmaceuticals, Inc. |
Inselspital, Bern University Hospital Basle_ Stroke Center Neurology, Basle UniversitätsSpital Zürich, Zürich Klinik Hirslanden, Zürich |
Kantonale Ethikkommission Bern | Ethikkommission Nordwest- und Zentralschweiz EKNZ, Kantonale Ethikkommission Zürich | 21.09.2020 | Study has ended | ||