| BASEC ID | Project title | Type of project | Type of clinical trial | Study phase (clinical trials only) | multi- / monocentric | Category | Principal investigator | Sponsor | Investigational sites | Lead EC | Local EC(s) | Approval date | Minors | Study Ended | |
|---|---|---|---|---|---|---|---|---|---|---|---|---|---|---|---|
| 2017-00636 | An open-label early access phase IIIb study of trifluridine / tipiracil (S 95005/TAS-102) in patients with a pretreated metastatic colorectal cancer. | clinical trial | drugs | phase 3 | monocentric | C | Prof. Dr. Roger von Moos | I.R.I.S. |
Kantonsspital Graubünden, Mediznischen Onkologie/Hämatologie, Chur |
Kantonale Ethikkommission Zürich | 21.07.2017 | Study has ended | |||
| 2017-00635 | Assessment of tumor infiltrating lymphocytes and characterization of the inflammatory infiltrate before, during and after immunotherapy of patients with melanoma and non-small cell lung cancer. | personal data/biological material | monocentric | Prof. Dr. med. Lukas Flatz |
Kantonsspital St. Gallen, St. Gallen |
Ethikkommission Ostschweiz (EKOS) | 11.04.2017 | ||||||||
| 2017-00634 | Evaluation of incidence and predictors for the development of pain following spinal cord injury | non clinical, involving persons | monocentric | A | Dr. Rachel Müller | Swiss Paraplegic Research |
Swiss Paraplegic Research, Nottwil |
Ethikkommission Nordwest- und Zentralschweiz EKNZ | 31.05.2017 | ||||||
| 2017-00633 | Spatiotemporal gait analysis and functional outcome after surgical treatment of calcaneal fracture in children | non clinical, involving persons | monocentric | A | Dr Aline Bregou Bourgeois, MD | CHUV - Dpt Femme-mère Enfant |
CHUV, Lausanne |
Commission cantonale d'Éthique de la Recherche sur l'être humain Vaud (CER-VD) | 07.07.2017 | yes | Study has ended | ||||
| 2017-00631 | Einsatz der Koronar-Computertomografie im klinischen Alltag - Übereinstimmung mit den aktuellen ESC-Guidelines; Vergleich der erhobenen Befunde mit der invasiven Koronarangiografie. | personal data/biological material | monocentric | PD Dr. Micha Maeder | Kantonsspital St.Gallen |
Kantonsspital St.Gallen, St.Gallen |
Ethikkommission Ostschweiz (EKOS) | 13.04.2017 | Study has ended | ||||||
| 2017-00630 | Exposure to metal working fluids and early effect biomarkers: oxidative stress, inflammation and genotoxicity. | non clinical, involving persons | monocentric | A | Dr Sauvain Jean-Jacques | INRS |
Institute for Work and Health, Lausanne |
Commission cantonale d'Éthique de la Recherche sur l'être humain Vaud (CER-VD) | 14.06.2017 | ||||||
| 2017-00629 | Patient Satisfaction following Hardware Removal after Surgical Treatment of Lateral Malleolar Fractures | non clinical, involving persons | monocentric | A | Dr. med. PhD Matthias Erschbamer |
KSSG Orthopädie, St. Gallen |
Ethikkommission Ostschweiz (EKOS) | 20.04.2017 | |||||||
| 2017-00628 | Verteilung von Alkohol, Kokain und deren Abbauprodukte in Kopfhaaren | non clinical, involving persons | monocentric | A | Prof. Dr. med. Dipl. phys. / Eva / Scheurer | Institut für Rechtsmedizin der Universität Basel |
Institut für Rechtsmedizin der Universität Basel, Basel |
Ethikkommission Nordwest- und Zentralschweiz EKNZ | 14.06.2017 | Study has ended | |||||
| 2017-00626 | Placebo-controlled trial in subjects at ultra-high risk for psychosis with omega-3 fatty acids in Europe | clinical trial | drugs | phase 3 | monocentric | B | Prof. Susanne Walitza | Brain Center Rudolf Magnus |
Psychiatrische Universitätsklinik, Zürich |
Kantonale Ethikkommission Zürich | 18.08.2017 | yes | |||
| 2017-00625 | Etude REPRo: Analyse rétrospective de l’issue de l’exposition à des médicaments durant la grossesse signalés au service de pharmacologie et toxicologie cliniques de 1994 à 2016. | personal data/biological material | monocentric | Dr. Victoria Rollason | HUG |
HUG, Genève |
Commission Cantonale d'éthique de la recherche Genève (CCER) | 04.05.2017 | Study has ended | ||||||
| 2017-00624 | Biomarker research CAIN457F2305: Bone metabolism and radiographic progression in ankylosing spondylitis; Does Secukinumab slow down/ inhibit spinal radiographic progression? | personal data/biological material | monocentric | Dr. Rainer Hillenbrand | NIBR |
Novartis Pharma AG, Basel |
Ethikkommission Nordwest- und Zentralschweiz EKNZ | 12.04.2017 | |||||||
| 2017-00623 | Pattern of Use and Safety/Effectiveness of Nivolumab in Routine Oncology Practice | personal data/biological material | multicentric | Dr. Augusto Pedrazzini | Bristol-Myers Squibb |
Fondazione Oncologia Lago Maggiore, 6600 Locarno Kantonsspital Baden, Med. Onkologie, Im Ergel 1, 5404 Baden Fondazione Oncologia Lago Maggiore, Locarno |
Kantonale Ethikkommission Zürich | Ethikkommission Nordwest- und Zentralschweiz EKNZ, Comitato etico cantonale Ticino | 06.06.2017 | ||||||
| 2017-00622 | Palmar Arch Insufficiency as a Risk Factor for Radial Artery Occlusion after Transradial Catheterization – a Single-Centre Observational Study | non clinical, involving persons | monocentric | A | Prof Christian Seiler |
Cardiology, Bern Universitay Hospital, Bern |
Kantonale Ethikkommission Bern | 30.08.2017 | |||||||
| 2017-00621 | Positive emotions and reward processing in individuals with and without developmental disorders | non clinical, involving persons | monocentric | A | Dr. Andrea Samson | Uniersity of Geneva_Swiss Center for Affective Sciences (CISA) |
Swiss Center for Affective Sciences - University of Geneva, Geneva |
Commission Cantonale d'éthique de la recherche Genève (CCER) | 30.05.2017 | yes | |||||
| 2017-00620 | In-hospital medical thromboprophylaxis: a single-center prospective quality improvement study | non clinical, involving persons | monocentric | A | Dr Marc Blondon | Geneva University Hospitals |
Geneva University Hospitals, Geneva |
Commission Cantonale d'éthique de la recherche Genève (CCER) | 30.05.2017 | ||||||
| 2017-00619 | TofaSwiss Study - A real life experience with tofacitinib: Data from the Swiss SCQM registry on safety | personal data/biological material | monocentric | Prof. Dr. med Jean Dudler | SCQM Foundation |
Hospital of Fribourg, Fribourg |
Commission cantonale d'Éthique de la Recherche sur l'être humain Vaud (CER-VD) | 15.06.2017 | |||||||
| 2017-00618 | A Post-Approval Registry of the TREO® Stent-Graft for Patients with Infrarenal Abdominal Aortic Aneurysms | non clinical, involving persons | monocentric | A | Dr Jos C. van den Berg | Bolton Medical |
CENTRO VASCOLARE TICINO, Ospedale Regionale di Lugano, sede Civico, Lugano |
Comitato etico cantonale Ticino | 11.07.2017 | ||||||
| 2017-00617 | Causal role of frontopolar cortex for motivation in healthy older adults: a transcranial direct current stimulation study | clinical trial | other clinical trials | monocentric | A | Prof. Dr. Philippe Tobler | Velux |
University of Zurich, Zürich |
Kantonale Ethikkommission Zürich | 03.07.2017 | |||||
| 2017-00615 | Predictors for optimal Timing of Antenatal Corticosteroids in Women with anticipated Preterm Birth | personal data/biological material | monocentric | Prof. Dr. med Irene Hösli | Chefärztin Frauenklinik USB |
Frauenklinik USB, Basel |
Ethikkommission Nordwest- und Zentralschweiz EKNZ | 22.05.2017 | |||||||
| 2017-00614 | Conservative management of spine fractures in a specialized outpatient clinic: epidemiology, practice, challenges and outcomes | personal data/biological material | monocentric | Stefan Schaeren | Spine Surgery |
Spine Surgery, University Hospital Basel, Basel |
Ethikkommission Nordwest- und Zentralschweiz EKNZ | 05.05.2017 | |||||||