BASEC ID Project title Type of project Type of clinical trial Study phase (clinical trials only) multi- / monocentric Category Principal investigator Sponsor Investigational sites Lead EC Local EC(s) Approval date Minors Study Ended
2017-00636 An open-label early access phase IIIb study of trifluridine / tipiracil (S 95005/TAS-102) in patients with a pretreated metastatic colorectal cancer. clinical trial drugs phase 3 monocentric C Prof. Dr. Roger von Moos I.R.I.S. Kantonsspital Graubünden, Mediznischen Onkologie/Hämatologie, Chur
Kantonale Ethikkommission Zürich 21.07.2017 Study has ended
2017-00635 Assessment of tumor infiltrating lymphocytes and characterization of the inflammatory infiltrate before, during and after immunotherapy of patients with melanoma and non-small cell lung cancer. personal data/biological material monocentric Prof. Dr. med. Lukas Flatz Kantonsspital St. Gallen, St. Gallen
Ethikkommission Ostschweiz (EKOS) 11.04.2017
2017-00634 Evaluation of incidence and predictors for the development of pain following spinal cord injury non clinical, involving persons monocentric A Dr. Rachel Müller Swiss Paraplegic Research Swiss Paraplegic Research, Nottwil
Ethikkommission Nordwest- und Zentralschweiz EKNZ 31.05.2017
2017-00633 Spatiotemporal gait analysis and functional outcome after surgical treatment of calcaneal fracture in children non clinical, involving persons monocentric A Dr Aline Bregou Bourgeois, MD CHUV - Dpt Femme-mère Enfant CHUV, Lausanne
Commission cantonale d'Éthique de la Recherche sur l'être humain Vaud (CER-VD) 07.07.2017 yes Study has ended
2017-00631 Einsatz der Koronar-Computertomografie im klinischen Alltag - Übereinstimmung mit den aktuellen ESC-Guidelines; Vergleich der erhobenen Befunde mit der invasiven Koronarangiografie. personal data/biological material monocentric PD Dr. Micha Maeder Kantonsspital St.Gallen Kantonsspital St.Gallen, St.Gallen
Ethikkommission Ostschweiz (EKOS) 13.04.2017 Study has ended
2017-00630 Exposure to metal working fluids and early effect biomarkers: oxidative stress, inflammation and genotoxicity. non clinical, involving persons monocentric A Dr Sauvain Jean-Jacques INRS Institute for Work and Health, Lausanne
Commission cantonale d'Éthique de la Recherche sur l'être humain Vaud (CER-VD) 14.06.2017
2017-00629 Patient Satisfaction following Hardware Removal after Surgical Treatment of Lateral Malleolar Fractures non clinical, involving persons monocentric A Dr. med. PhD Matthias Erschbamer KSSG Orthopädie, St. Gallen
Ethikkommission Ostschweiz (EKOS) 20.04.2017
2017-00628 Verteilung von Alkohol, Kokain und deren Abbauprodukte in Kopfhaaren non clinical, involving persons monocentric A Prof. Dr. med. Dipl. phys. / Eva / Scheurer Institut für Rechtsmedizin der Universität Basel Institut für Rechtsmedizin der Universität Basel, Basel
Ethikkommission Nordwest- und Zentralschweiz EKNZ 14.06.2017 Study has ended
2017-00626 Placebo-controlled trial in subjects at ultra-high risk for psychosis with omega-3 fatty acids in Europe clinical trial drugs phase 3 monocentric B Prof. Susanne Walitza Brain Center Rudolf Magnus Psychiatrische Universitätsklinik, Zürich
Kantonale Ethikkommission Zürich 18.08.2017 yes
2017-00625 Etude REPRo: Analyse rétrospective de l’issue de l’exposition à des médicaments durant la grossesse signalés au service de pharmacologie et toxicologie cliniques de 1994 à 2016. personal data/biological material monocentric Dr. Victoria Rollason HUG HUG, Genève
Commission Cantonale d'éthique de la recherche Genève (CCER) 04.05.2017 Study has ended
2017-00624 Biomarker research CAIN457F2305: Bone metabolism and radiographic progression in ankylosing spondylitis; Does Secukinumab slow down/ inhibit spinal radiographic progression? personal data/biological material monocentric Dr. Rainer Hillenbrand NIBR Novartis Pharma AG, Basel
Ethikkommission Nordwest- und Zentralschweiz EKNZ 12.04.2017
2017-00623 Pattern of Use and Safety/Effectiveness of Nivolumab in Routine Oncology Practice personal data/biological material multicentric Dr. Augusto Pedrazzini Bristol-Myers Squibb Fondazione Oncologia Lago Maggiore, 6600 Locarno
Kantonsspital Baden, Med. Onkologie, Im Ergel 1, 5404 Baden
Fondazione Oncologia Lago Maggiore, Locarno
Kantonale Ethikkommission Zürich Ethikkommission Nordwest- und Zentralschweiz EKNZ, Comitato etico cantonale Ticino 06.06.2017
2017-00622 Palmar Arch Insufficiency as a Risk Factor for Radial Artery Occlusion after Transradial Catheterization – a Single-Centre Observational Study non clinical, involving persons monocentric A Prof Christian Seiler Cardiology, Bern Universitay Hospital, Bern
Kantonale Ethikkommission Bern 30.08.2017
2017-00621 Positive emotions and reward processing in individuals with and without developmental disorders non clinical, involving persons monocentric A Dr. Andrea Samson Uniersity of Geneva_Swiss Center for Affective Sciences (CISA) Swiss Center for Affective Sciences - University of Geneva, Geneva
Commission Cantonale d'éthique de la recherche Genève (CCER) 30.05.2017 yes
2017-00620 In-hospital medical thromboprophylaxis: a single-center prospective quality improvement study non clinical, involving persons monocentric A Dr Marc Blondon Geneva University Hospitals Geneva University Hospitals, Geneva
Commission Cantonale d'éthique de la recherche Genève (CCER) 30.05.2017
2017-00619 TofaSwiss Study - A real life experience with tofacitinib: Data from the Swiss SCQM registry on safety personal data/biological material monocentric Prof. Dr. med Jean Dudler SCQM Foundation Hospital of Fribourg, Fribourg
Commission cantonale d'Éthique de la Recherche sur l'être humain Vaud (CER-VD) 15.06.2017
2017-00618 A Post-Approval Registry of the TREO® Stent-Graft for Patients with Infrarenal Abdominal Aortic Aneurysms non clinical, involving persons monocentric A Dr Jos C. van den Berg Bolton Medical CENTRO VASCOLARE TICINO, Ospedale Regionale di Lugano, sede Civico, Lugano
Comitato etico cantonale Ticino 11.07.2017
2017-00617 Causal role of frontopolar cortex for motivation in healthy older adults: a transcranial direct current stimulation study clinical trial other clinical trials monocentric A Prof. Dr. Philippe Tobler Velux University of Zurich, Zürich
Kantonale Ethikkommission Zürich 03.07.2017
2017-00615 Predictors for optimal Timing of Antenatal Corticosteroids in Women with anticipated Preterm Birth personal data/biological material monocentric Prof. Dr. med Irene Hösli Chefärztin Frauenklinik USB Frauenklinik USB, Basel
Ethikkommission Nordwest- und Zentralschweiz EKNZ 22.05.2017
2017-00614 Conservative management of spine fractures in a specialized outpatient clinic: epidemiology, practice, challenges and outcomes personal data/biological material monocentric Stefan Schaeren Spine Surgery Spine Surgery, University Hospital Basel, Basel
Ethikkommission Nordwest- und Zentralschweiz EKNZ 05.05.2017