| BASEC ID | Project title | Type of project | Type of clinical trial | Study phase (clinical trials only) | multi- / monocentric | Category | Principal investigator | Sponsor | Investigational sites | Lead EC | Local EC(s) | Approval date | Minors | Study Ended | |
|---|---|---|---|---|---|---|---|---|---|---|---|---|---|---|---|
| 2020-02921 | Cerebrospinal fluid extracellular vesicles as a source of molecular biomarkers of disease progression in multiple sclerosis | non clinical, involving persons | monocentric | B | Dr Claire Bridel | HUG |
HUG, Genève |
Commission Cantonale d'éthique de la recherche Genève (CCER) | 15.02.2021 | ||||||
| 2020-02920 | Retrospektive Analyse von Netzhautablösungen mit Makulabeteiligung | personal data/biological material | monocentric | Dr. med. Christof Hänsli | Berner Augenklinik am Lindenhofspital |
Berner Augenklinik am Lindenhofspital, Bern |
Kantonale Ethikkommission Bern | 19.02.2021 | Study has ended | ||||||
| 2020-02918 | Retinale endotheliale Dysfunktion bei Raynaud-Phänomen – Fall-Kontroll-Studie | non clinical, involving persons | monocentric | A | PD Dr. med. Thomas Neumann | KSSG |
KSSG, St. Gallen |
Ethikkommission Ostschweiz (EKOS) | 14.01.2021 | ||||||
| 2020-02916 | Liver Cancer Treated with Selective Internal Radiation Therapy: The Role of Body Composition Analysis in the Assessment of Tumour Response and Patient Outcomes | personal data/biological material | monocentric | Dr Rafael Duran | CHUV - Radiodiagnostic |
Centre Hospitalier Universitaire Vaudois (CHUV), Lausanne |
Commission cantonale d'Éthique de la Recherche sur l'être humain Vaud (CER-VD) | 09.08.2021 | |||||||
| 2020-02915 | Etude rétrospective des patients atteints d’hépatites cholestatiques chroniques associées à l’identification de variants au sein des gènes incriminés dans les formes familiales de cholestase | personal data/biological material | monocentric | Dre Monserrat Fraga | CHUV |
CHUV, Lausanne |
Commission cantonale d'Éthique de la Recherche sur l'être humain Vaud (CER-VD) | 03.02.2021 | Study has ended | ||||||
| 2020-02913 | A cohort study to elucidate the effects of Metformin on steroid hormones and social behaviour in affected subjects with autism – a first pilot study | clinical trial | drugs | n/a | monocentric | A | Prof. Markus Mohaupt |
Lindenhofspital, Bern |
Kantonale Ethikkommission Bern | 06.04.2021 | Study has ended | ||||
| 2020-02912 | KISS Study (Keep bIfurcation Single stenting Simple) | clinical trial | medical devices | monocentric | A1 | Dr. Vladimir Rubimbura | CERIC (CEnter for European Research Initiatives in Cardiovascular medicine) |
CHUV Centre Hospitalier Universitaire Vaudois, Lausanne |
Commission cantonale d'Éthique de la Recherche sur l'être humain Vaud (CER-VD) | 23.03.2021 | Study has ended | ||||
| 2020-02911 | The use of the EXCOR® Active driving unit for mobilization of pediatric patients with ventricular assist device support | clinical trial | medical devices | multicentric | C3 | Martin Schweiger | Berlin Heart GmbH |
Kispi ZH, Zürich CHUV, Lausanne |
Kantonale Ethikkommission Zürich | Commission cantonale d'Éthique de la Recherche sur l'être humain Vaud (CER-VD) | 23.02.2021 | yes | |||
| 2020-02910 | Clinical and molecular characterization of patients with Hereditary Angioedema at the Division of Allergy of the University Hospital Basel and at the Department of Oncology/Hematology at the Universit More ... | non clinical, involving persons | monocentric | A | Prof. Dr. med. Karin Hartmann | Universität Basel |
Universität Basel, Basel |
Ethikkommission Nordwest- und Zentralschweiz EKNZ | 26.03.2021 | yes | |||||
| 2020-02909 | Non-motor burden in patients with Parkinson disease and essential tremor undergoing deep brain stimulation – a retrospective study (PDET-NMS-DBS) | personal data/biological material | monocentric | Prof. Dr. med. Christian Baumann | University Hospital Zurich |
University Hospital Zurich, Department of Neurology, Zurich |
Kantonale Ethikkommission Zürich | 02.02.2021 | |||||||
| 2020-02908 | GN41851/ FENhance 1: PHASE III MULTICENTER, RANDOMIZED, DOUBLE-BLIND, DOUBLE-DUMMY, PARALLEL-GROUP STUDY TO EVALUATE THE EFFICACY AND SAFETY OF FENEBRUTINIB COMPARED WITH TERIFLUNOMIDE IN ADULT PATIE More ... | clinical trial | drugs | phase 3 | multicentric | C | Dr. med. Oliver Findling | Roche Pharma (Schweiz) AG |
Kantonsspital Aarau, Aarau Universitätsklinik für Neurologie, Inselspital Bern, Bern Neurologia, Ospedale Regionale di Lugano Civico, Lugano |
Ethikkommission Nordwest- und Zentralschweiz EKNZ | Kantonale Ethikkommission Bern, Comitato etico cantonale Ticino | 22.04.2021 | |||
| 2020-02907 | An open-label observation parallel study to evaluate the effect of treatment with Cladribine on the immune response following vaccination in patients with Multiple Sclerosis within the Swiss Multiple More ... | personal data/biological material | monocentric | PD Dr.med Matthias Mehling | University Hospital Basel |
University Hospital Basel, Basel |
Ethikkommission Nordwest- und Zentralschweiz EKNZ | 10.12.2020 | |||||||
| 2020-02906 | MK-1308A-004: A Phase 2, Multicenter, Clinical Study to Evaluate the Safety and Efficacy of MK-1308A (Coformulated MK-1308/MK-3475) in Combination with Lenvatinib (E7080/MK-7902) in First-line Therapy More ... | clinical trial | drugs | phase 2 | multicentric | C | Prof. Dr. Andreas Kremer | Merck Sharp & Dohme LLC |
UniversitätsSpital Zürich, Zürich Inselspital Bern, Bern Kantonsspital St. Gallen, St. Gallen Centre Hospitalier Universitaire Vaudois, Lausanne |
Kantonale Ethikkommission Zürich | Ethikkommission Ostschweiz (EKOS), Kantonale Ethikkommission Bern, Commission cantonale d'Éthique de la Recherche sur l'être humain Vaud (CER-VD) | 23.02.2021 | Study has ended | ||
| 2020-02905 | Ocular surface samples donation for research purposes at F. Hoffmann-La Roche Ltd, Basel and Kaiseraugst | non clinical, involving persons | monocentric | A | Dr. Federica Storti | F. Hoffmann-La Roche Ltd |
F. Hoffmann-La Roche Ltd, pRED Ophthalmology, Basel |
Ethikkommission Nordwest- und Zentralschweiz EKNZ | 22.01.2021 | ||||||
| 2020-02904 | The association of physical activity and sedentary behavior with cognitive function, mental health and health-related quality of life in older adults with subjective cognitive decline (SCD): Baseline More ... | personal data/biological material | monocentric | Prof. Dr. med. Heike Annette Bischoff-Ferrari, DrPH | Klinik für Geriatrie |
Klinik für Geriatrie, Zürich |
Kantonale Ethikkommission Zürich | 22.12.2020 | |||||||
| 2020-02903 |
Head-to-head comparison of 68Ga-PSMA-11 and 18F-PSMA-1007 for the detection of recurrent prostate cancer in PSMA-ligand PET/CT A prospective, single centre, open label, dual-arm, randomised, cross-ov More ... |
clinical trial | drugs | n/a | monocentric | C | Prof. Dr. med. Ali Afshar-Oromieh | Inselspital |
Inselspital, Bern |
Kantonale Ethikkommission Bern | 27.05.2022 | Study has ended | |||
| 2020-02902 | Assessment of the diagnostic value of 7T MRI in diseases of the central nervous system | personal data/biological material | monocentric | Dr. med. Piotr Radojewski | Institute of Diagnostic and Interventional Neuroradiology |
Institute of Diagnostic and Interventional Neuroradiology, University Hospital, Bern |
Kantonale Ethikkommission Bern | 09.04.2021 | |||||||
| 2020-02901 | Perception of the impact of COVID-19 in cancer patients: a single-institutional prospective observational study (survey) | non clinical, involving persons | monocentric | A | Dr. med Piercarlo Saletti | Clinica Luganese Moncucco |
Clinica Luganese Moncucco, Lugano |
Comitato etico cantonale Ticino | 05.02.2021 | ||||||
| 2020-02900 | An External Control, Observational, Retrospective Study Assessing the Effect of Pralsetinib Compared with Best Available Therapy for Patients with RET-Fusion Positive Advanced Non-Small Cell Lung Canc More ... | personal data/biological material | monocentric | Oliver Gautschi | Blueprint Medicines |
Lucerne Cantonal Hospital, Lucerne |
Ethikkommission Nordwest- und Zentralschweiz EKNZ | 17.12.2020 | |||||||
| 2020-02899 | Implementation of a clinical screening and response system for perioperative myocardial infarction/injury after noncardiac surgery: feasibility and medicoeconomic impact | non clinical, involving persons | multicentric | A | Dr. Christian Puelacher | University Hospital Basel |
University Hospital Basel, Basel Canton Hospital Lucerne, Lucerne Hospital Olten, Olten Bürgerspital Solothurn, Solothurn University Hospital Geneva, Geneva |
Ethikkommission Nordwest- und Zentralschweiz EKNZ | Ethikkommission Nordwest- und Zentralschweiz EKNZ, Commission Cantonale d'éthique de la recherche Genève (CCER) | 01.03.2021 | |||||