| BASEC ID | Project title | Type of project | Type of clinical trial | Study phase (clinical trials only) | multi- / monocentric | Category | Principal investigator | Sponsor | Investigational sites | Lead EC | Local EC(s) | Approval date | Minors | Study Ended | |
|---|---|---|---|---|---|---|---|---|---|---|---|---|---|---|---|
| 2017-00592 | Concurrent chemoradiation with Volumetric Modulated Arc Therapy of patients treated for anal cancer. Acute toxicity and treatment outcome | personal data/biological material | monocentric | Dr Kaloyan Yordanov |
IOSI, Bellinzona |
Comitato etico cantonale Ticino | 27.04.2017 | ||||||||
| 2017-00590 | Impact of anhedonia on group cognitive-behavioral therapy outcomes in patients with insomnia | personal data/biological material | monocentric | Dr. med. Wolfgang Schmitt | Swiss Government Excellence Scholarship for Foreign Scholars and Artists |
University Psychiatric Depertment, Inselspital, Bern |
Kantonale Ethikkommission Bern | 14.06.2017 | |||||||
| 2017-00589 | Prise en charge, évolution et complications des fractures distales de l’ulna associées à une fracture de l’extrémité distale du radius | non clinical, involving persons | monocentric | A | Morgan Gauthier | Hôpitaux Universitaires de Genève |
Hôpitaux Universitaires de Genève, Genève |
Commission Cantonale d'éthique de la recherche Genève (CCER) | 13.06.2017 | ||||||
| 2017-00588 | Early versus Late initiation of direct oral Anticoagulants in post-ischaemic stroke patients with atrial fibrillatioN (ELAN): an international, multicentre, randomised-controlled, two-arm, assessor-bl More ... | clinical trial | drugs | n/a | multicentric | A | Dr. med. Thomas Horvath | Inselspital |
Inselspital, Bern Kantonsspital Luzern, Luzern Kantonsspital Aarau, Aarau Universitätsspital Basel, Basel Kantonsspital Baden, Baden Universitätsspital Genf, Genf Kantonsspital St. Gallen, St.Gallen K More ... |
Kantonale Ethikkommission Bern | Ethikkommission Nordwest- und Zentralschweiz EKNZ, Ethikkommission Ostschweiz (EKOS), Kantonale Ethikkommission Zürich, Commission cantonale d'Éthique de la Recherche sur l'être humain Vaud (CER-VD), More ... | 05.10.2017 | |||
| 2017-00587 | A Phase 1/2 Study of the Combination of Lirilumab (Anti-KIR) Plus Nivolumab (Anti-PD-1) or Lirilumab Plus Nivolumab and Ipilimumab in Advanced Refractory Solid Tumors | clinical trial | drugs | phase 1/2 | multicentric | C | Prof. Dr. Roger von Moos | Bristol-Myers Squibb International Corporation |
Kantonsspital Graubünden, Chur Département d’Oncologie CHUV, Lausanne |
Kantonale Ethikkommission Zürich | Commission cantonale d'Éthique de la Recherche sur l'être humain Vaud (CER-VD) | 04.07.2017 | Study has ended | ||
| 2017-00586 |
Evaluation of RAF + MEK inhibitor resistance in fresh biopsies, cell lines and mouse xenografts from human melanoma tumors |
personal data/biological material | monocentric | Dr. Michael Rugaard Jensen | NIBR |
Novartis Pharma AG, Basel |
Ethikkommission Nordwest- und Zentralschweiz EKNZ | 10.04.2017 | |||||||
| 2017-00585 | ADCHIP: A biomarker chip-assay in preserved red blood cells for the diagnosis of Alzheimer’s Disease | non clinical, involving persons | monocentric | A | Prof. Jean-Francois Demonet | Amoneta Diagnostics |
Leenaards Memory Center - CHUV, Lausanne |
Commission cantonale d'Éthique de la Recherche sur l'être humain Vaud (CER-VD) | 28.09.2017 | ||||||
| 2017-00584 |
SAKK 08/15 PROMET - Multicenter, Randomized Phase II Trial of Salvage Radiotherapy +/- Metformin for Patients with Prostate Cancer after Prostatectomy |
clinical trial | drugs | phase 2 | multicentric | B | Prof. Dr. med. Daniel Aebersold | SAKK | Inselspital in collaboration with the following institutions: Radio-Onkologiezentrum Biel-Seeland-Berner Jura AG (ROZ), Radio-Onkologie Berner Oberland (ROBO) and Radio-Onkologie Solothurn (ROSOL), Be More ... | Kantonale Ethikkommission Bern | Ethikkommission Nordwest- und Zentralschweiz EKNZ, Ethikkommission Ostschweiz (EKOS), Kantonale Ethikkommission Zürich, Commission cantonale d'Éthique de la Recherche sur l'être humain Vaud (CER-VD), More ... | 08.09.2017 | Study has ended | ||
| 2017-00583 | 15834_Phase 1b multi-indication study of anetumab ravtansine (BAY 94-9343) in patients with mesothelin expressing advanced or recurrent malignancies | clinical trial | drugs | phase 1 | multicentric | C | Prof. Dr. med. Roger von Moos | Bayer (Schweiz) AG |
Kantonsspital Graubünden Hauptstandort, Chur Institute of Oncology of Southern Switzerland, Bellinzona |
Kantonale Ethikkommission Zürich | Comitato etico cantonale Ticino | 17.07.2017 | Study has ended | ||
| 2017-00581 | Einfluss des Reflexbogens bestimmter Hand-/Unterarmmuskeln, auf die Ausprägung der Funktionshand bei Patienten mit Tetraplegie. | non clinical, involving persons | monocentric | A | Dr. I.-M. Velstra | Schweizer Paraplegiker Zentrum |
Schweizer Paraplegiker Zentrum, Clinical Trial Unit, Nottwil |
Ethikkommission Nordwest- und Zentralschweiz EKNZ | 30.05.2017 | Study has ended | |||||
| 2017-00580 |
Cerebral microbleeds and cognitive function: leading figures in dementia pathophysiology or fortuitous association? |
personal data/biological material | monocentric | Dr Aline Mendes | Hôpitaux Universitaires de Genève |
Geneva University Hospitals, Geneva |
Commission Cantonale d'éthique de la recherche Genève (CCER) | 06.06.2017 | |||||||
| 2017-00579 | Craniospinal Irradiation Treatments at PSI: follow-up Analysis and Treatment optimization | personal data/biological material | monocentric | Alessandra Bolsi | Center for Proton Therapy, Paul Scherrer Institute |
Center for Proton Therapy, Paul Scherrer Institute, Villigen |
Ethikkommission Nordwest- und Zentralschweiz EKNZ | 04.05.2017 | Study has ended | ||||||
| 2017-00578 |
Pilot – Study Comparison of image performance of TURBO-PET detector vs. standard detector using a dbPET scanner in breast cancer patients |
non clinical, involving persons | monocentric | A | Prof. John Prior | CHUV |
CHUV, Lausanne |
Commission cantonale d'Éthique de la Recherche sur l'être humain Vaud (CER-VD) | 29.12.2017 | ||||||
| 2017-00577 | Is Orthodontic Treatment Associated with Cervical Invasive Root Resorption? A Case-Control Study. | non clinical, involving persons | monocentric | A | Dr. Dan-Krister Rechenberg | University of Zurich |
University of Zurich, Center of Dental Medicine, Clinic of Preventive Dentistry, Periodontology and Cariology, Zürich |
Kantonale Ethikkommission Zürich | 08.06.2017 | ||||||
| 2017-00576 | A Phase 3, multicenter, randomized, double-blind, double-dummy, active-controlled study to assess the efficacy and safety of maribavir compared to valganciclovir for the treatment of cytomegalovirus ( More ... | clinical trial | drugs | phase 3 | monocentric | C | Prof. Dr. med. Nicolas Müller | Takeda Development Center Americas, Inc. (TDCA), |
Universitätshospital Zürich, Zürich |
Kantonale Ethikkommission Zürich | 23.06.2017 | yes | Study has ended | ||
| 2017-00575 | Contrast-Enhanced Ultrasound as Novel Imaging Modality for Follow-Up Imaging of Patients with Solid Organ Injuries – A Prospective Observational Study | non clinical, involving persons | monocentric | B | PD Dr. med. Beat Schnüriger | University Clinic for Visceral Surgery and Medicine, Division of Acute Care Surgery |
Universitätsklinik für Viszerale Chirurgie und Medizin, Bern |
Kantonale Ethikkommission Bern | 16.12.2019 | ||||||
| 2017-00573 | Assessment of bacterial translocation on the incidence of surgical site infection in abdominal surgery: Prospective cohort study. | non clinical, involving persons | monocentric | A | Prof.Dr./Guido/Beldi | Universitätsklinik für Viszerale Chirurgie und Medizin, Inselspital |
Inselspital, Bern |
Kantonale Ethikkommission Bern | 10.05.2017 | ||||||
| 2017-00572 | Combined endovascular and microsurgical treatment for cerebral dural arteriovenous fistulas in the hybrid operating room | personal data/biological material | monocentric | Prof. Javier Fandino | Kantonsspital Aarau |
Kantonsspital Aarau, Aarau |
Ethikkommission Nordwest- und Zentralschweiz EKNZ | 02.05.2017 | Study has ended | ||||||
| 2017-00571 |
Enhanced vincristine neurotoxicity in adult patients with haematological malignancies treated with fluconazole |
personal data/biological material | monocentric | Pierre-Yves Bochud | CHUV - BH 10 553 |
Centre Hospitalier Universitaire Vaudois, Lausanne |
Commission cantonale d'Éthique de la Recherche sur l'être humain Vaud (CER-VD) | 26.04.2017 | |||||||
| 2017-00570 | CPDR001G2101: A phase Ib study of PDR001 in combination with sorafenib in patients with advanced hepatocellular carcinoma (HCC). | clinical trial | drugs | phase 1 | monocentric | C | Prof. Jean-Francois Dufour | Novartis Pharma Schweiz AG |
Insel AG, Bern |
Kantonale Ethikkommission Bern | 17.08.2017 | Study has ended | |||