| BASEC ID | Project title | Type of project | Type of clinical trial | Study phase (clinical trials only) | multi- / monocentric | Category | Principal investigator | Sponsor | Investigational sites | Lead EC | Local EC(s) | Approval date | Minors | Study Ended | |
|---|---|---|---|---|---|---|---|---|---|---|---|---|---|---|---|
| 2023-01218 | Monotherapy with a P2Y12 inhibitor followed by a direct-acting oral anticoagulant in patients with ATRial fIbrillation undergoing suprafleX coronary stent implantation (MATRIX-2) | clinical trial | other clinical trials | multicentric | B | Prof. Stephan Windecker | Insel Gruppe AG Bern University Hospital |
Inselspital, Bern University Hospital, Bern Universitätsspital Basel, Klinik für Kardiologie, Basel Hôpitaux Universitaires de Genève,, Genève Cardiocentro Ticino Institute, Ente Ospedaliero Cantonale More ... |
Kantonale Ethikkommission Bern | Ethikkommission Nordwest- und Zentralschweiz EKNZ, Kantonale Ethikkommission Zürich, Commission Cantonale d'éthique de la recherche Genève (CCER), Comitato etico cantonale Ticino | 29.09.2023 | ||||
| 2023-01217 | Fully digital occlusion planning in orthognathic surgery | personal data/biological material | multicentric | Prof. Dr. med. Dr. med. dent. Philipp Metzler | Kantonsspital Aarau |
Kantonsspital Aarau, Aarau Universitätsspital Basel, Basel |
Ethikkommission Nordwest- und Zentralschweiz EKNZ | Ethikkommission Nordwest- und Zentralschweiz EKNZ | 24.07.2023 | ||||||
| 2023-01216 | Infrared thermography to monitor breast cancer patients during neoadjuvant chemotherapy: An exploratory analysis | non clinical, involving persons | monocentric | A | Dr. med. Lorenzo Rossi | Istituto Oncologico della Svizzera Italiana |
Istituto Oncologico della Svizzera Italiana, Bellinzona |
Comitato etico cantonale Ticino | 23.08.2023 | ||||||
| 2023-01215 | Prädiktive Faktoren für den Aufenthaltsort von Patient:innen nach einer Neurorehabilitation – Eine prospektive Machbarkeitsstudie | non clinical, involving persons | monocentric | A | PhD Clare Maguire | REHAB Basel |
REHAB Basel, Basel |
Ethikkommission Nordwest- und Zentralschweiz EKNZ | 13.09.2023 | ||||||
| 2023-01214 | Changes in body composition, self-reported symptoms and costs in one menstrual cycle: An explorative evaluation and cost analysis | non clinical, involving persons | monocentric | A | Prof. Dr. Heiner Baur | Berner Fachhochschule |
Berner Fachhochschule, Bern |
Kantonale Ethikkommission Bern | 24.08.2023 | ||||||
| 2023-01213 | Semaglutide-to-Tirzepatid-Switch (STS-3)-Studie: Prospektive Beobachtungsstudie eines zusätzlichen Effekts auf die glykämische Kontrolle und das Körpergewicht bei Patienten mit Diabetes, die von einer More ... | personal data/biological material | multicentric | Prof. Dr. Gottfried Rudofsky | Praxis Prof. Rudofsky |
Praxis Prof. Rudofsky, Olten Stoffwechselzentrum St. Gallen, St. Gallen |
Ethikkommission Nordwest- und Zentralschweiz EKNZ | Ethikkommission Ostschweiz (EKOS) | 23.08.2023 | ||||||
| 2023-01212 | The causal effect of surgical and orthotics treatments to improve walking in persons with a neurological disorder, including cerebral palsy and those toe walking. | personal data/biological material | multicentric | Dr. Morgan Sangeux | UKBB |
UKBB, Basel HUG, Genève |
Ethikkommission Nordwest- und Zentralschweiz EKNZ | Commission Cantonale d'éthique de la recherche Genève (CCER) | 24.08.2023 | ||||||
| 2023-01211 | A Phase 3, Multicenter, Randomized, Double-Blind, Placebo-Controlled Study to Assess the Efficacy and Safety of REL-1017 as Adjunctive Treatment for Major Depressive Disorder | clinical trial | drugs | phase 3 | monocentric | C | Prof. Dr. med. Andrea Raballo | MGGM LLC |
Organizzazione sociopsichiatrica cantonale, Mendrisio |
Comitato etico cantonale Ticino | 21.02.2024 | ||||
| 2023-01210 | Management of benign and pre-invasive breast lesions: Comparison of rates of histologic underestimation in minimally invasive breast biopsies between 2000-2007 and 2008-2022 and investigation of patie More ... | personal data/biological material | monocentric | Dr. med. Cristian Bronz | Universitätsspital Zürich |
Universitätsspital Zürich, Zürich |
Kantonale Ethikkommission Zürich | 30.08.2023 | |||||||
| 2023-01209 | A real-world retrospective analysis of non-small cell lung cancer (NSCLC) patients in a single centre: clinical outcome and prognostic value of molecular alterations | personal data/biological material | monocentric | Dr. med. Patrizia Froesch | Istituto Oncologico della Svizzera Italiana (IOSI) |
Istituto Oncologico della Svizzera Italiana (IOSI), Bellinzona |
Comitato etico cantonale Ticino | 13.07.2023 | |||||||
| 2023-01208 | SUNSHINE_BIO: Understanding the molecular basis of differential responses to prostate cancer treatments in a comprehensive retrospective cohort. | personal data/biological material | monocentric | Dr. med. Ricardo Pereira Mestre | Istituto oncologico della Svizzera Italiana (IOSI) |
Instituto Oncologico della Svizzera Italiana (IOSI), Bellinzona |
Comitato etico cantonale Ticino | 06.09.2023 | |||||||
| 2023-01207 |
A Phase 1, First-in-Human, Open-label Study Evaluating the Safety, Tolerability, Pharmacokinetics, and Efficacy of TT125-802 in Subjects with Advanced Solid Tumors Étude de phase 1, de première adm More ... |
clinical trial | drugs | phase 1 | multicentric | C | Dr Krisztian Homicsko | Tolremo Therapeutics AG |
Département d'Oncologie, Service d’Immuno-Oncologie, Centre Hospitalier Universitaire Vaudois (CHUV), Lausanne Ospedale Regionale di Bellinzona e Valli, Bellinzona |
Commission cantonale d'Éthique de la Recherche sur l'être humain Vaud (CER-VD) | Comitato etico cantonale Ticino | 27.11.2023 | |||
| 2023-01206 | Validation du kit ELISA IgG anti-β2GP1 pour l’évaluation des risques de prééclampsie au premier trimestre de grossesse. | personal data/biological material | monocentric | Dr Marie Cohen | UNIGE |
University of Geneva, Geneva |
Commission Cantonale d'éthique de la recherche Genève (CCER) | 16.10.2023 | |||||||
| 2023-01205 | Comparaison des profils de patients.e.s atteints.e.s d'une insuffisance cardiaque terminale et de patients.e.s atteint.e.s d'un cancer avancé suivi.e.s par l'équipe mobile de soins palliatifs intrahos More ... | personal data/biological material | monocentric | Dr. Michel Beauverd | CHUV - Soins palliatifs |
CHUV, Lausanne |
Commission cantonale d'Éthique de la Recherche sur l'être humain Vaud (CER-VD) | 31.07.2023 | |||||||
| 2023-01204 | Fat oxidation and muscle deoxygenation kinetics during graded exercise in hypoxia | non clinical, involving persons | monocentric | A | Dr. / Davide / Malatesta | ISSUL - UNIL |
ISSUL - UNIL, Lausanne |
Commission cantonale d'Éthique de la Recherche sur l'être humain Vaud (CER-VD) | 16.08.2023 | ||||||
| 2023-01202 | A Comparison of the Neuromechanical Characteristics of Different Exercises Commonly Used to Test and Train Lower Limb Extension Power in Athletes. | non clinical, involving persons | monocentric | A | Dr. phil. Nicola Maffiuletti | Schulthess Klinik |
Schulthess Klinik, Zürich |
Kantonale Ethikkommission Zürich | 15.08.2023 | ||||||
| 2023-01201 | Barbed suture in pancreaticojejuneal anastomosis: a potential ally against pancreatic fistula. | personal data/biological material | monocentric | Dr. Rosita Sortino | St. Claraspital |
Clarunis, Basel |
Ethikkommission Nordwest- und Zentralschweiz EKNZ | 07.07.2023 | |||||||
| 2023-01200 | Étude rétrospective de la complexité bio-psycho-sociale et système de soins des patients hospitalisés en unité de Soins Palliatifs à la Fondation Rive-Neuve sur l’année 2019 (ECSP). | personal data/biological material | monocentric | FRIEDRICH STIEFEL, Prof. Dr. med. | CHUV - Psychiatrie de Liaison |
Centre Hospitalier Universitaire Vaudois (CHUV), Lausanne |
Commission cantonale d'Éthique de la Recherche sur l'être humain Vaud (CER-VD) | 24.08.2023 | |||||||
| 2023-01199 | A Multi-Cohort, Randomised, Placebo-Controlled Phase 2a Study to Assess the Safety, Pharmacokinetics, Pharmacodynamics and Clinical Activity of Ascending Doses of RXC007 in Patients with Idiopathic Pu More ... | clinical trial | drugs | phase 2 | monocentric | C | Prof. Anne Bergeron | Redx Pharma Plc |
Hôpitaux Universitaires de Genève, Geneva |
Commission Cantonale d'éthique de la recherche Genève (CCER) | 23.10.2023 | ||||
| 2023-01196 | Metacognitive Intervention in youth with Oncological disease | clinical trial | other clinical trials | monocentric | A | Prof.Dr.phil. Regula Everts | Inselspital Bern |
Inselspital, Bern |
Kantonale Ethikkommission Bern | 31.08.2023 | yes | ||||