BASEC ID Project title Type of project Type of clinical trial Study phase (clinical trials only) multi- / monocentric Category Principal investigator Sponsor Investigational sites Lead EC Local EC(s) Approval date Minors Study Ended
2018-02102 COMB157G2399 - An open-label, single arm, multi-center extension study evaluating long-term safety, tolerability and effectiveness of ofatumumab in subjects with relapsing multiple sclerosis clinical trial drugs phase 3 multicentric C Prof. Dr. med. Tobias Derfuss Novartis Pharma Schweiz AG Universitätsspital, Basel
Ospedale Regionale di Lugano, Lugano
Ethikkommission Nordwest- und Zentralschweiz EKNZ Comitato etico cantonale Ticino 08.03.2019
2018-02101 Dissecting the tolerogenic immune response to the synergic activity of polyomavirus BK and IDO personal data/biological material monocentric PD Dr med Maurizio Provenzano University Hospital of Zurich University Hospital of Zurich, Schlieren
Kantonale Ethikkommission Zürich 03.12.2018
2018-02100 Analyse rétrospective de l'électrophysiologie intraopératoire personal data/biological material monocentric Dr sc. Colette Boëx Hôpitaux Universitaires de Genève University Hospital of Geneva, Geneva
Commission Cantonale d'éthique de la recherche Genève (CCER) 04.12.2018
2018-02099 Importance of exercise training therapy timing with regard to cardiotoxicity and patient preference in early breast cancer and lymphoma patients undergoing adjuvant chemo-therapy clinical trial other clinical trials monocentric A Prof. Dr. med. Matthias Wilhelm Preventive Cardiology & Sports Medicine Präventive Kardiologie & Sportmedizin, Universitätsklinik für Kardiologie, Inselspital, Bern
Kantonale Ethikkommission Bern 14.03.2019 Study has ended
2018-02098 Facteurs contribuant à l’hémolyse in vitro d’un échantillon sanguin non clinical, involving persons monocentric A Dr Michel Rossier Sarstedt AG Hôpital du Valais, Sion
Commission cantonale d'Éthique de la Recherche sur l'être humain Vaud (CER-VD) 12.03.2019 Study has ended
2018-02097 MK-7902-003: A Phase 3 Randomized, Placebo-controlled Trial to Evaluate the Safety and Efficacy of Pembrolizumab (MK-3475) and Lenvatinib (E7080/MK-7902)Versus Pembrolizumab Alone as First-line Interv More ... clinical trial drugs phase 3 multicentric C Prof. Dr. med. Reinhard Dummer Merck Sharp & Dohme LLC UniversitätsSpital Zürich, Zürich
Universitätsspital Basel, Basel
Kantonsspital Graubünden, Chur
Kantonsspital Winterthur, Winterthur
Kantonale Ethikkommission Zürich Ethikkommission Nordwest- und Zentralschweiz EKNZ, Kantonale Ethikkommission Zürich 30.01.2019 Study has ended
2018-02096 Cognitive fatigue and fatigability in multiple sclerosis: brain mechanisms and biomarkers. non clinical, involving persons monocentric A PhD Stefano Magon University Hospital Basel University Hospital Basel, Basel
Ethikkommission Nordwest- und Zentralschweiz EKNZ 19.12.2018 Study has ended
2018-02095 Le rôle de l'expertise psychiatrique légale dans les mesures coercitives à des fins d'assistance (Vaud, Valais et Genève) personal data/biological material multicentric Professeure associée Cristina Ferreira HESAV HESAV, Lausanne
HESAV, Lausanne
Commission cantonale d'Éthique de la Recherche sur l'être humain Vaud (CER-VD) Commission Cantonale d'éthique de la recherche Genève (CCER) 01.02.2019 Study has ended
2018-02094 Evaluation of the safety of fat grafting in the prevention of pressure injuries (Masterthese) personal data/biological material monocentric PD Dr. med. Reto Wettstein University Hospital Basel University Hospital Basel, Basel
Ethikkommission Nordwest- und Zentralschweiz EKNZ 19.12.2018 Study has ended
2018-02093 Long time follow up in a bariatric surgery center, outcomes in weight loss and comorbidities personal data/biological material monocentric Dr. med. Romano Schneider Universitätsspital Basel Universitätsspital Basel, Basel
Ethikkommission Nordwest- und Zentralschweiz EKNZ 04.12.2018
2018-02092 Controlled Attenuated Parameter (CAP) for the Assessment of Liver Steatosis in an Unselected Patient Population personal data/biological material monocentric Dr. Stephan Baumeler KSSG KSSG, St. Gallen
Ethikkommission Ostschweiz (EKOS) 21.11.2018
2018-02091 Indication, Impact d'un examen IRM sur la patiente et son suivi gynécologique, chez les jeunes femmes avec suspicion d'endométriose au CHUV. non clinical, involving persons monocentric A Dre. Martine Jacot-Guillarmod CHUV, Lausanne
Commission cantonale d'Éthique de la Recherche sur l'être humain Vaud (CER-VD) 30.01.2019 Study has ended
2018-02090 RESCUE ESES: a Randomized European trial of Steroids versus Clobazam Usage for Encephalopathy with Electrical Status Epilepticus in Sleep clinical trial drugs phase 3 monocentric B PD Dr. med. Georgia Ramantani PhD University Medical Centre Utrecht Universitäts-Kinderspital Zürich, Zürich
Kantonale Ethikkommission Zürich 08.01.2019 yes
2018-02089 Central Pain Processing, Psychosocial and Lifestyle Factors as potential Predictors and / or Moderators for Outcome after Rotator Cuff Repair: A Study Design for a Prospective Longitudinal Cohort Stud More ... personal data/biological material monocentric Ariane Schwank Kantonsspital Winterthur Kantonsspital Winterthur, Winterthur
Kantonale Ethikkommission Zürich 30.01.2019
2018-02088 Effects of restricting intravenous fluids vs. standard care fluid therapy in patients with septic shock
The Conservative vs. Liberal Approach to fluid therapy of Septic Shock in Intensive Care (CLASS More ...
clinical trial other clinical trials multicentric A PD Dr.med. Carmen A. Pfortmueller University of Kopenhangen Department of Intensive Care, Inselspital, Bern University Hospital, Bern
Klinik für Intensivmedizin, Basel
Kantonale Ethikkommission Bern Ethikkommission Nordwest- und Zentralschweiz EKNZ 20.06.2019 Study has ended
2018-02087 CBLZ945X2101 - A phase I/II, open-label, multi-center study of the safety and efficacy of BLZ945 as single agent and in combination with PDR001 in adults patients with advanced solid tumors clinical trial drugs phase 1/2 multicentric C Prof. Nicolas Mach Novartis Pharma Schweiz AG HUG, Genève
UniversitätsSpital Zürich USZ, Zürich
Commission Cantonale d'éthique de la recherche Genève (CCER) Kantonale Ethikkommission Zürich 06.02.2019 Study has ended
2018-02086 Pulmonary function test association with clinical, laboratory, histological and radiological characteristic - a prospective study non clinical, involving persons monocentric A Prof Dr Daiana Stolz Clinic of Pneumology, University Hospital Basel, Basel
Ethikkommission Nordwest- und Zentralschweiz EKNZ 22.02.2019
2018-02085 Evaluation de la performance diagnostique de l’imagerie hybride hfSPECT/US dans la recherche préopératoire d’adénome parathyroïdien non clinical, involving persons monocentric A Prof. John Prior CHUV CHUV, Lausanne
Commission cantonale d'Éthique de la Recherche sur l'être humain Vaud (CER-VD) 03.01.2019 Study has ended
2018-02084 Analyse rétrospective d'une cohorte d'enfants présentant une extravasation personal data/biological material monocentric Dr Francois Vermeulen HUG HUG, Genève
Commission Cantonale d'éthique de la recherche Genève (CCER) 08.01.2019
2018-02083 1702 HALT - Targeted therapy with or without dose intensified radiotherapy for oligo-progressive disease in oncogene-addicted lung tumours clinical trial other clinical trials multicentric A Guckenberger Matthias EORTC UniversitaetsSpital Zurich, Zurich
Hôpitaux universitaires de Genève - HUG - site de Cluse-Roseraie, Genève
Kantonsspital St Gallen, St Gallen
Oncology Institute of Southern Switzerland (IOSI) - Onco More ...
Kantonale Ethikkommission Zürich Ethikkommission Ostschweiz (EKOS), Kantonale Ethikkommission Zürich, Commission Cantonale d'éthique de la recherche Genève (CCER), Comitato etico cantonale Ticino 29.04.2019