| BASEC ID | Project title | Type of project | Type of clinical trial | Study phase (clinical trials only) | multi- / monocentric | Category | Principal investigator | Sponsor | Investigational sites | Lead EC | Local EC(s) | Approval date | Minors | Study Ended | |
|---|---|---|---|---|---|---|---|---|---|---|---|---|---|---|---|
| 2021-02451 | TRI0346 –Exploratory Metabolite Profiling and Bioanalytical Enantioselective Assessment of the Main Circulating Metabolite in Selected Plasma Samples Obtained Following Multiple Dosing of ENV396 in St More ... | personal data/biological material | monocentric | PhD Anne Gardin | Novartis Pharma AG - NIBR |
Novartis Pharma AG, Basel |
Ethikkommission Nordwest- und Zentralschweiz EKNZ | 17.12.2021 | |||||||
| 2021-02448 | Companion Diagnostic Study: ONCOMINE DX TARGET TEST CLINICAL TRIAL ASSAY PROTOCOL: BIOMARKER RET FUSIONS (SABRETOOTH) PROSPECTIVE STUDY – PRJ0002373 | personal data/biological material | monocentric | Alexandre Fort | Thermofisher |
Labcorp, Geneva |
Commission Cantonale d'éthique de la recherche Genève (CCER) | 21.12.2021 | |||||||
| 2021-02447 |
Restrictive vs Standard Fluid Management in Mechanically Ventilated Children Admitted to PICU - a Pilot Randomised Controlled Trial REDUCE-1 |
clinical trial | other clinical trials | monocentric | A | Prof. Dr. med. Luregn Schlapbach | The University of Queensland ABN 63 942 912 684 |
Universitäts-Kinderspital Zürich, Zürich |
Kantonale Ethikkommission Zürich | 17.05.2022 | yes | ||||
| 2021-02446 | Gait profiles of Alzheimer's and subcortical vascular dementia under single and dual task walking conditions | personal data/biological material | monocentric | Dr. med. Stephanie A. Bridenbaugh | University Department of Geriatric Medicine FELIX PLATTER |
University Department of Geriatric Medicine FELIX PLATTER, Basel |
Ethikkommission Nordwest- und Zentralschweiz EKNZ | 02.02.2022 | |||||||
| 2021-02444 | Determinants of sexual dimorphism in Head/Neck Squamous Cell Carcinoma. | personal data/biological material | monocentric | Prof. Paolo Dotto | CHUV - Bureau Promoteur de la Recherche |
CHUV, Lausanne |
Commission cantonale d'Éthique de la Recherche sur l'être humain Vaud (CER-VD) | 07.03.2022 | |||||||
| 2021-02443 | Protection of life versus quality of life in the old people living in nursing homes and their relatives during the COVID-19 pandemic | non clinical, involving persons | multicentric | A | Prof Claudia Ortoleva Bucher | Haute Ecole de la Santé La Source |
Haute Ecole de la Santé La Source, Lausanne Berner Fachhochschule, Bern University of Applied Sciences and Arts of Southern Switzerland, Manno |
Commission cantonale d'Éthique de la Recherche sur l'être humain Vaud (CER-VD) | Kantonale Ethikkommission Bern, Comitato etico cantonale Ticino | 02.03.2022 | |||||
| 2021-02441 | Infectious Complications of Indwelling Pleural Catheters. | personal data/biological material | monocentric | Dr. med. Marco Previsdomini |
Medicina intensiva ORBV, Bellinzona |
Comitato etico cantonale Ticino | 21.01.2022 | ||||||||
| 2021-02440 | Prévalence et facteurs prédictifs de l'automutilation et de la suicidalité chez les adolescents hospitalisés dans une unité hospitalière de psychiatrie pour adolescents : Une étude rétrospective sur d More ... | personal data/biological material | monocentric | Prof. Marco Armando | CHUV - UHPA |
CHUV, Lausanne |
Commission cantonale d'Éthique de la Recherche sur l'être humain Vaud (CER-VD) | 25.03.2022 | |||||||
| 2021-02439 | Feasibility and Pilot Study of Virtual Reality Aggression Prevention Training (VRAPT) for Forensic Psychiatric Patients | clinical trial | other clinical trials | monocentric | A | Cyril Boonmann | Psychiatric University Hospitals (UPK) Basel |
Psychiatric University Hospitals (UPK) Basel, Basel |
Ethikkommission Nordwest- und Zentralschweiz EKNZ | 12.04.2022 | yes | ||||
| 2021-02437 |
Multicenter Prospective Cohort Study on Current Treatments of Legg-Calvé-Perthes Disease (IPSG - International Perthes study Group) |
non clinical, involving persons | monocentric | A | Dr Sophie Merckaert | Texas Scottish Rite Hospital for children in Dallas |
CHUV, Lausanne |
Commission cantonale d'Éthique de la Recherche sur l'être humain Vaud (CER-VD) | 11.03.2022 | yes | |||||
| 2021-02436 | Self-rotation perception using visual and vestibular stimuli relies on prior information and sensory fusion | non clinical, involving persons | monocentric | A | Dr Christopher Bockisch | UniversitätsSpital Zürich |
UniversitätsSpital Zürich, Zürich |
Kantonale Ethikkommission Zürich | 08.03.2022 | ||||||
| 2021-02435 | Schwellwerte für die Frakturrisiko-Beurteilung bei Personen mit einer Rückenmarkverletzung anhand der Knochenmineraldichtemessungen im Knie | personal data/biological material | monocentric | Dr. sc. ETH Patrik Wyss | Schweizer Paraplegiker Zentrum |
Schweizer Paraplegiker Zentrum, Nottwil |
Ethikkommission Nordwest- und Zentralschweiz EKNZ | 05.01.2022 | Study has ended | ||||||
| 2021-02434 | Method optimization for the quantification of the NAD (Nicotinamide Adenine Dinucleotide) metabolome in human whole blood, plasma, and urine, and evaluation of baseline inter and intra-subject variabi More ... | non clinical, involving persons | monocentric | A | Nathalie Piccardi | Nestlé Health Science |
Société des Produits Nestlé, Lausanne |
Commission cantonale d'Éthique de la Recherche sur l'être humain Vaud (CER-VD) | 08.02.2022 | Study has ended | |||||
| 2021-02433 | STOP? II trial: Cluster randomized clinical trial to test the implementation of a toolbox for structured communication in the operating room | clinical trial | other clinical trials | multicentric | A | Prof Dr Guido Beldi | Bern University Hospital |
Inselspital, Bern CHUV, Lausanne |
Kantonale Ethikkommission Bern | Commission cantonale d'Éthique de la Recherche sur l'être humain Vaud (CER-VD) | 14.03.2022 | ||||
| 2021-02432 | Evolutionary and ecological epidemiology across scales: within- and between-host dynamics of Escherichia coli | non clinical, involving persons | monocentric | A | Dr Sonja Lehtinen | ETH Zurich |
ETH Zurich, Zurich |
Kantonale Ethikkommission Zürich | 25.01.2022 | yes | |||||
| 2021-02431 | Colorectal cancer screening decisions based on predicted risk: the PREcision ScreENing randomized controlled Trial (PRESENT) | clinical trial | other clinical trials | monocentric | A | Dr Kevin Selby | Unisanté |
Unisanté, Lausanne |
Commission cantonale d'Éthique de la Recherche sur l'être humain Vaud (CER-VD) | 02.03.2022 | |||||
| 2021-02429 | Langzeitnachbeobachtung der Blasenfunktion nach laparoskopischer Sacrocolpopexie bei Patientinnen mit präoperativ bestehender Blasenfunktionsstörung: eine prospektive Kohortenstudie | non clinical, involving persons | monocentric | A | PD Dr. med. Corina Christmann | Luzerner Kantonsspital |
Beckenbodenzentrum Luzerner Kantonsspital, Luzern |
Ethikkommission Nordwest- und Zentralschweiz EKNZ | 26.01.2022 | ||||||
| 2021-02428 | 20210023 - A phase 1/1b/2 study evaluating the safety, tolerability, pharmacokinetics, pharmacodynamics, and efficacy of AMG 193 alone and in combination with docetaxel in subjects with advanced MTAP- More ... | clinical trial | drugs | phase 1/2 | multicentric | C | Dr. med. Alfredo Addeo | Amgen Inc. |
Hopitaux Universitaires de Geneve, Geneve Universitätsklinik für Medizinische Onkologie, Inselspital Bern, Bern Istituto Oncologico della Svizzera Italiana, Bellinzona |
Commission Cantonale d'éthique de la recherche Genève (CCER) | Kantonale Ethikkommission Bern, Comitato etico cantonale Ticino | 13.06.2022 | |||
| 2021-02427 |
Wirkung von Beta-Blocker Einnahme, v.a. Propanolol, auf den Krankheitsverlauf und klinischen Outcome von Patienten mit der Diagnose eines cerebralen/spinalen Angioms. |
personal data/biological material | monocentric | Prof. Dr. med. Gerrit Schubert | Kantonsspital Aarau AG |
Kantonsspital Aarau, Aarau |
Ethikkommission Nordwest- und Zentralschweiz EKNZ | 18.12.2021 | |||||||
| 2021-02426 | Multimodal Magnetic Resonance Imaging (MRI) for diagnosis of spinal metastases and response assessment after Stereotactic Body Radiation Therapy (SBRT) | non clinical, involving persons | monocentric | A | Dr. med. Hossein Hemmatazad | Inselspital Bern |
Inselspital Bern, Universtitätsklinik für Radio-Onkologie, Bern |
Kantonale Ethikkommission Bern | 17.06.2022 | ||||||