| BASEC ID | Project title | Type of project | Type of clinical trial | Study phase (clinical trials only) | multi- / monocentric | Category | Principal investigator | Sponsor | Investigational sites | Lead EC | Local EC(s) | Approval date | Minors | Study Ended | |
|---|---|---|---|---|---|---|---|---|---|---|---|---|---|---|---|
| 2024-01768 | A Phase II, Open-label Study to Evaluate the Safety, Tolerability, Pharmacokinetics, Immunogenicity, and Antitumor Activity of Volrustomig Priming Regimens in Combination with other Anticancer Agents More ... | clinical trial | drugs | phase 2 | multicentric | C | Dr. med. Laetitia Mauti | AstraZeneca AB |
Kantonsspital Winterthur, Winterthur Universitätsspital Basel, Basel Hôpitaux Universitaires de Genève, Genève CHUV, Centre hospitalier universitaire vaudois, Lausanne UniversitätsSpital Zürich, Züric More ... |
Kantonale Ethikkommission Zürich | Ethikkommission Nordwest- und Zentralschweiz EKNZ, Kantonale Ethikkommission Zürich, Commission cantonale d'Éthique de la Recherche sur l'être humain Vaud (CER-VD), Commission Cantonale d'éthique de l More ... | 17.12.2024 | |||
| 2024-01767 |
The Swiss Integrated Care (INCA) Study: Establishing a Cohort Study of Patients in Supported Family Care |
non clinical, involving persons | monocentric | A | Prof. Dr. Viktor von Wyl | University of Zurich |
University of Zurich, Zurich |
Kantonale Ethikkommission Zürich | 10.01.2025 | ||||||
| 2024-01766 | Thyroidectomy for Graves' Disease or Amiodarone-induced Thyrotoxicosis: Is it still necessary to achieve a preoperative euthyroid state? – A prospective observational multicenter European study | personal data/biological material | multicentric | Dr. Andrea Goldmann | Kantonsspital Winterthur |
Kantonsspital Winterthur, Winterthur Inselspital Bern, Bern Clarunis St. Claraspital, Basel Kantonsspital Baselland, Liestal University of Geneva, Geneva Kantonsspital St. Gallen, St. Gallen Hospitale More ... |
Kantonale Ethikkommission Zürich | Ethikkommission Nordwest- und Zentralschweiz EKNZ, Ethikkommission Ostschweiz (EKOS), Kantonale Ethikkommission Bern, Kantonale Ethikkommission Zürich, Commission cantonale d'Éthique de la Recherche s More ... | 01.04.2025 | ||||||
| 2024-01765 | A Phase 3, Randomized, Open-Label, Active-Controlled Study to Evaluate a Switch to an Oral Weekly Islatravir/Lenacapavir Regimen in People With HIV‑1 Who Are Virologically Suppressed on Standard of Ca More ... | clinical trial | drugs | phase 3 | multicentric | C | Prof. Dr. med. Matthias Cavassini | Gilead Sciences, Inc. |
CHUV, Lausanne Inselspital, Bern HUG, Genève |
Commission cantonale d'Éthique de la Recherche sur l'être humain Vaud (CER-VD) | Kantonale Ethikkommission Bern, Commission Cantonale d'éthique de la recherche Genève (CCER) | 23.12.2024 | |||
| 2024-01764 | Utilization of Volatile Organic Compounds for Monitoring Treatment Responses, Detection of Postoperative Complications and Tumor Follow Up in Esophageal Cancer | non clinical, involving persons | monocentric | A | Dr. med. Dr. sc. nat. Marcel Schneider | UniversitätsSpital Zürich |
Department of Visceral- and Transplant Surgery, University Hospital Zurich, Zurich |
Kantonale Ethikkommission Zürich | 10.01.2025 | ||||||
| 2024-01763 | A Phase 3, Randomized, Double-Blind, Active-Controlled Study to Evaluate a Switch to an Oral Weekly Islatravir/Lenacapavir Regimen in People With HIV-1 Who Are Virologically Suppressed on Bictegravir/ More ... | clinical trial | drugs | phase 3 | multicentric | C | Prof. Dr. med. Matthias Cavassini | Gilead Sciences, Inc. |
CHUV, Lausanne Inselspital, Bern USZ, Zürich |
Commission cantonale d'Éthique de la Recherche sur l'être humain Vaud (CER-VD) | Kantonale Ethikkommission Bern, Kantonale Ethikkommission Zürich | 23.12.2024 | |||
| 2024-01762 | A comparative study of the Quantra® QStat System with rotational thromboelastometry (ROTEM® sigma) and standard laboratory coagulation tests in an obstetric population | non clinical, involving persons | monocentric | A | Dre Alexia Cuenoud | CHUV - Anesthésiologie |
CHUV, Lausanne |
Commission cantonale d'Éthique de la Recherche sur l'être humain Vaud (CER-VD) | 05.05.2025 | ||||||
| 2024-01761 | MK-1022-011: A Phase 1/2 Study to Evaluate the Safety and Efficacy of Patritumab Deruxtecan in Gastrointestinal Cancers | clinical trial | drugs | phase 1/2 | multicentric | C | Dr. med. Thibaud Kössler | Merck Sharp & Dohme LLC |
Hôpitaux Universitaires Genève (HUG), Genève UniversitätsSpital Zürich, Zürich |
Commission Cantonale d'éthique de la recherche Genève (CCER) | Kantonale Ethikkommission Zürich | 07.11.2024 | |||
| 2024-01760 | Epidemiologische Analyse von Krankheiten und Risikofaktoren anhand von Autopsien. | personal data/biological material | monocentric | Dr. Umberto Maccio | Universitätsspital Zürich |
Universitätsspital Zürich, Institut für Pathologie und Molekularpathologie, Zürich |
Kantonale Ethikkommission Zürich | 17.12.2024 | |||||||
| 2024-01758 |
1 year minimum follow up after AMIC plastic of focal chondral defects of the first metatarsal head in beginning MTP I arthritis |
non clinical, involving persons | monocentric | A | PD Dr. med. Stephan Wirth | Universitätsklinik Balgrist |
Universitätsklinik Balgrist, Zürich |
Kantonale Ethikkommission Zürich | 15.11.2024 | ||||||
| 2024-01757 | Eine Beobachtungsstudie zur Anwendung von aerosoliertem Capsaicin zur Sekretmobilisation bei Patient:innen auf der Intensivstation | personal data/biological material | monocentric | PD Dr. med Philipp Bühler | Kantonsspital Winterthur |
Kantonsspital Winterthur, Winterthur |
Kantonale Ethikkommission Zürich | 01.11.2024 | |||||||
| 2024-01756 | In-hospital obesity measurement: discrepancy between prevalence and actual documentation | personal data/biological material | monocentric | Dr. méd. Alend Saadi | RHNe - Chirurgie |
Réseau Hospitalier Neuchâtelois, Neuchâtel |
Commission cantonale d'Éthique de la Recherche sur l'être humain Vaud (CER-VD) | 03.12.2024 | |||||||
| 2024-01755 | Neural correlates of craving in alcohol use disorder. | non clinical, involving persons | monocentric | A | PD Dr. med. Marcus Herdener | University of Zurich |
University of Zurich, Zurich |
Kantonale Ethikkommission Zürich | 10.12.2024 | ||||||
| 2024-01754 | Investigation of physiological networks of sleep for memory consolidation in temporal lobe epilepsy with HD-EEG | non clinical, involving persons | monocentric | A | Project Leader (Prof Serge Vulliémoz, PhD) | Hôpitaux Universitaires de Genève |
Hôpitaux Universitaires de Genève, Geneva |
Commission Cantonale d'éthique de la recherche Genève (CCER) | 28.01.2025 | ||||||
| 2024-01753 | Survival and quality of life in patient with alcoholic steatohepatitis according to treatment | non clinical, involving persons | monocentric | A | PD Dr. med. Sena Blümel | GAE USZ |
Klinik für Gastroenterologie und Hepatologie, Universitätsspital Zürich, Zürich |
Kantonale Ethikkommission Zürich | 07.03.2025 | ||||||
| 2024-01752 | Descriptive epidemiology, evaluation of infection control measures, and assessment of transmission parameters of influenza virus at an acute care hospital in Switzerland: 2010-2024 | personal data/biological material | monocentric | Prof. Stephan Harbarth | Hôpitaux Universitaires de Genève |
Hôpitaux Universitaires de Genève, Genève |
Commission Cantonale d'éthique de la recherche Genève (CCER) | 09.12.2024 | |||||||
| 2024-01751 | Targeting “inflammaging” by NAD boosting plus CD38 inhibitiOn as longevity nutritional strategy in fRAil oLder subjects: the CORAL study. Exploratory phase | non clinical, involving persons | monocentric | A | Prof Patrizia D'Amelio | CHUV - Gériatrie |
CHUV University Hospital, Lausanne |
Commission cantonale d'Éthique de la Recherche sur l'être humain Vaud (CER-VD) | 11.11.2024 | ||||||
| 2024-01749 | Etude rétrospective de capacité d'effort et de la qualité de vie des patients admis en réhabilitation respiratoire en Suisse | personal data/biological material | monocentric | Pr Pierre-Olivier Bridevaux | Hôpital du Valais |
Hôpital du Valais, Martigny |
Commission cantonale d'Éthique de la Recherche sur l'être humain Vaud (CER-VD) | 27.01.2025 | |||||||
| 2024-01748 | L’effet vécu des médicaments antidépresseurs : exploration qualitative phénoménologique | non clinical, involving persons | monocentric | A | Dr. Michael Saraga | CHUV - Psychiatrie |
CHUV, Lausanne |
Commission cantonale d'Éthique de la Recherche sur l'être humain Vaud (CER-VD) | 26.11.2024 | ||||||
| 2024-01747 | LACPYSEP - Lactate to pyruvate ratio to assess tissue dysoxia in septic shock. | non clinical, involving persons | monocentric | A | Dr Zied Ltaief | CHUV - SMIA |
CHUV, Lausanne |
Commission cantonale d'Éthique de la Recherche sur l'être humain Vaud (CER-VD) | 16.10.2024 | ||||||