BASEC ID Project title Type of project Type of clinical trial Study phase (clinical trials only) multi- / monocentric Category Principal investigator Sponsor Investigational sites Lead EC Local EC(s) Approval date Minors Study Ended
2017-00233 European Multinational Prolongation Registry on Prevention of Thromboembolic Events In Atrial Fibrillation non clinical, involving persons monocentric A Tiziano Moccetti Daiichi Sankyo Europe GmbH Cardiocentro Ticino, Lugano
Comitato etico cantonale Ticino 30.03.2017
2017-00232 An exploratory proof-of mechanism study to assess the effect of Ruxolitinib on tumor infiltrating myeloid cells and additional immune subsets in prostate cancer patients clinical trial drugs n/a monocentric B MD Andrea Alimonti Institute of Oncology Research (IOR), Oncology Institute of Southern Switzerland (IOSI), Bellinzona
Comitato etico cantonale Ticino 18.08.2017 Study has ended
2017-00231 Single center follow up of patients suffering from AML and MDS with aberrant EVI1 expression personal data/biological material monocentric Dr Jonathan Bloch Service d'Hématologie CHUV CHUV, Lausanne
Commission cantonale d'Éthique de la Recherche sur l'être humain Vaud (CER-VD) 09.03.2017
2017-00230 Short-term functional toxicity of liver stereotactic body radiotherapy evaluated with 99mTc-mebrofenin hepatobiliary scintigraphy (HBS)
personal data/biological material monocentric Dr Berardino De Bari CHUV - service de radiothérapie CHUV, Lausanne
Commission cantonale d'Éthique de la Recherche sur l'être humain Vaud (CER-VD) 02.03.2017
2017-00229 Options and preferences concerning the resuscitation code
Communication during patient-physician encounters
non clinical, involving persons monocentric A Dre Eve Rubli Truchard Chaire de soins palliatifs gériatriques, CHUV Chaire de soins palliatifs gériatriques, CHUV, Lausanne
Commission cantonale d'Éthique de la Recherche sur l'être humain Vaud (CER-VD) 19.04.2017
2017-00228 ICON8B: A phase III randomised trial investigating the combination of dose-fractionated chemotherapy and bevacizumab compared to either strategy alone for the first-line treatment of women with newly More ... clinical trial drugs phase 3 multicentric B Prof. dr. med Cristiana Sessa MRC CTU CTU-EOC, Bellinzona
Inselspital, Bern University Hospital, 3010 Bern
Kantonsspital Frauenfeld, Frauenklinik, 8501 Frauenfeld
Comitato etico cantonale Ticino Ethikkommission Ostschweiz (EKOS), Kantonale Ethikkommission Bern 03.11.2017
2017-00227 High-intensity interval training as treatment strategy for heart failure patients with preserved ejection fraction: A prospective, single-blind, randomized controlled trial clinical trial other clinical trials multicentric B PD Dr. med. Thomas Dieterle Kantonsspital Baselland Cantonal Hospital Baselland, Liestal
Departement für Sport, Bewegung und Gesundheit der Universität Basel, Basel
Ethikkommission Nordwest- und Zentralschweiz EKNZ Ethikkommission Nordwest- und Zentralschweiz EKNZ 24.04.2017 Study has ended
2017-00226 Investigation of test-retest reliability of a neurophysiological cognitive test-battery non clinical, involving persons monocentric A Dr. Nicolas Langer University of Zurich University of Zurich, Zurich
Kantonale Ethikkommission Zürich 02.05.2017
2017-00225 Antithrombotics’ therapeutic optimization in hospitalized patients using physiologically- and population-based pharmacokinetic modeling non clinical, involving persons monocentric A Prof Jean-Luc Reny Hôpitaux Universitaires de Genève, Genève
Commission Cantonale d'éthique de la recherche Genève (CCER) 11.04.2017
2017-00224 Enhancing sleep dependent consolidation by non-invasive brain stimulation to boost motor skill acquisition in individuals after stroke clinical trial other clinical trials multicentric A Prof. Dr. med. Friedhelm Hummel EPFL, CNP EPFL, Geneva
EPFL Valais Wallis, SUVA, Sion
Commission Cantonale d'éthique de la recherche Genève (CCER) Commission cantonale d'Éthique de la Recherche sur l'être humain Vaud (CER-VD) 30.05.2017 Study has ended
2017-00223 Effect of phosphodiesterase-5 inhibition with Tadalafil on SystEmic Right VEntricular size and function – a multi-center, double-blind, randomized, placebo-controlled clinical trial – SERVE Trial clinical trial drugs phase 3 multicentric C Prof. Dr. Markus Schwerzmann Zentrum für angeborene Herzfehler Kardiologie, Inselspital, 3010 Bern
Kardiologie, Universitätsspital Basel, 4031 Basel
Service de Cardiologie HUG, 1205 Genève
Kardiologie, Kantonsspital St. Gallen, 9000 StGallen
Service de Cardiologi More ...
Kantonale Ethikkommission Bern Ethikkommission Nordwest- und Zentralschweiz EKNZ, Ethikkommission Ostschweiz (EKOS), Kantonale Ethikkommission Zürich, Commission cantonale d'Éthique de la Recherche sur l'être humain Vaud (CER-VD), More ... 25.04.2017 Study has ended
2017-00222 Einflussfaktoren auf Porinregulation von Gram negativen Bakterien während der antibiotischen Therapie personal data/biological material monocentric PD Dr. Dr. Adrian Egli Universitätsspital Basel University Hospital Basel, Basel
Ethikkommission Nordwest- und Zentralschweiz EKNZ 24.02.2017
2017-00220 An Observational Disease and Clinical Outcomes Registry of Patients with Lysosomal Acid Lipase (LAL) Deficiency non clinical, involving persons monocentric A PD Dr.med. Marianne Rohrbach Alexion Pharma GmbH Kinderspital Zürich, Zürich
Kantonale Ethikkommission Zürich 11.05.2017 yes Study has ended
2017-00219 Characteristics of Triple negative breast cancer (TNBC) and its subtypes in clinical imaging
personal data/biological material monocentric Dr. Constanze Elfgen Brust Zentrum Zürich Brust Zentrum , Zürich
Kantonale Ethikkommission Zürich 02.08.2017
2017-00218 Telephone-administered cognitive-behavioral relapse prevention for
patients with chronic and recurrent depression: A multi-center randomized
clinical trial
clinical trial other clinical trials multicentric A Prof. Dr. Birgit Watzke University of Zurich University of Zurich, Zürich
Universität Bern, Universitätsklinik für Psychiatrie und Psychotherapie, Bern
Privatklinik Meiringen Zentrum für seelische Gesundheit, Meiringen
Klinik SGM Langenthal, Lan More ...
Kantonale Ethikkommission Zürich Ethikkommission Nordwest- und Zentralschweiz EKNZ, Ethikkommission Ostschweiz (EKOS), Kantonale Ethikkommission Bern, Kantonale Ethikkommission Zürich, Commission cantonale d'Éthique de la Recherche s More ... 12.07.2017
2017-00217 Prevention of ischemia/reperfusion injury by C1 INH: Assessment of reperfusion injury in total knee arthroplasty. Pilot study clinical trial other clinical trials monocentric A Prof. Dr. Med. Dr. Phil. nat. Frank Klenke Cardiovascular research, DBMR, University of Bern Knee Surgery and Sports Traumatology, Dept. of Orthopaedics and Traumatology, University of Bern, Bern
Kantonale Ethikkommission Bern 02.08.2017
2017-00216 Impact de la sélection d’exercices pliométriques sur l’activation des ischio-jambiers chez les sprinters non clinical, involving persons monocentric A Mr Davide Malatesta Université de Lausanne, Lausanne
Commission cantonale d'Éthique de la Recherche sur l'être humain Vaud (CER-VD) 27.04.2017
2017-00215 GS-US-417-0302: A Randomized, Double-blind, Placebo-controlled, Multicenter, Phase
3 Study to Assess the Efficacy and Safety of Filgotinib Administered
for 24 weeks in Combination with Conventional More ...
clinical trial drugs phase 3 monocentric C PD Dr. med. Rüdiger Müller Gilead Sciences, Inc. Kantonsspital St. Gallen, Rheumatologie und Rehabilitation, St. Gallen
Ethikkommission Ostschweiz (EKOS) 11.04.2017 Study has ended
2017-00213 “Fast-Track versus Open-End Hospitalizations for Patients with Acute, Non-Disabling Ischemic Stroke Requiring Hospitalization: a Retrospective Cohort Study personal data/biological material monocentric PD Dr. De Marchis Stroke Center & Neurologische Klinik, Universitätsspital Basel Stroke Center & Neurologische Klinik, 4056 Basel
Ethikkommission Nordwest- und Zentralschweiz EKNZ 24.02.2017
2017-00212 A post-market registry of the BioMatrix Alpha™ (Cobalt Chromium Biolimus A9™ (BA9™) drug eluting stent non clinical, involving persons multicentric A PD Dr. med. Gregor Leibundgut Biosensors Europe SA Kantonsspital Baselland, Standort Liestal, Liestal
Stadtspital Triemli, Zürich
Ethikkommission Nordwest- und Zentralschweiz EKNZ Kantonale Ethikkommission Zürich 21.04.2017 Study has ended