| BASEC ID | Project title | Type of project | Type of clinical trial | Study phase (clinical trials only) | multi- / monocentric | Category | Principal investigator | Sponsor | Investigational sites | Lead EC | Local EC(s) | Approval date | Minors | Study Ended | |
|---|---|---|---|---|---|---|---|---|---|---|---|---|---|---|---|
| 2025-02371 | Feasibility and clinical implications of real-time cerebral autoregulation monitoring in major noncardiac surgery with the Medtronic Cotrending algorithm (AUTOREGULATE-NONCARDIAC-COTRENDING) | personal data/biological material | monocentric | Dr. med. Patrick M. Wanner | Anesthesiology, University Hospital Basel |
Anesthesiology, University Hospital Basel, Basel |
Ethikkommission Nordwest- und Zentralschweiz EKNZ | 17.12.2025 | |||||||
| 2025-02361 | Multi-omics profiling of tumor microenvironment of ovarian cancer | personal data/biological material | monocentric | Prof. Intidhar Labidi-Galy | HUG service d'Oncologie |
HUG- service d'oncologie, Genève |
Commission Cantonale d'éthique de la recherche Genève (CCER) | 22.12.2025 | |||||||
| 2025-02359 | Cytochrome P450 phenotyping in patients with severe neurodevelopmental disorders and pharmacoresistant challenging behaviors: a retrospective descriptive study | personal data/biological material | monocentric | Dr Vincent Guinchat | CHUV; section psychiatrique développement mental |
CHUV section psychiatrique développement mental, Prilly |
Commission cantonale d'Éthique de la Recherche sur l'être humain Vaud (CER-VD) | 04.12.2025 | |||||||
| 2025-02357 | A Phase 3, Randomized, Double-blind, Placebo-controlled, 3-Part Study to Evaluate the Efficacy and Safety of Orally Administered Deucrictibant XR Tablet for Prophylaxis and Deucrictibant Soft Capsule More ... | clinical trial | drugs | phase 3 | monocentric | C | Prof. Karin Hartmann | Pharvaris Netherlands B.V. |
Universitätsspital Basel, Basel |
Ethikkommission Nordwest- und Zentralschweiz EKNZ | 05.01.2026 | ||||
| 2025-02356 | COMPANION DIAGNOSTIC : Clinical Performance Study Protocol for Use of VENTANA PD-L1 (SP263) CDx Assay for Determining PD-L1 Expression Level in Advanced Biliary Tract Cancer Specimens from the Phase I More ... | personal data/biological material | monocentric | Dr. Olivier Venzin | Roche Tissue Diagnostic |
Labcorp CLS, Meyrin |
Commission Cantonale d'éthique de la recherche Genève (CCER) | 16.12.2025 | |||||||
| 2025-02353 |
Early-onset Rektumkarzinom |
personal data/biological material | monocentric | PD Dr. med. univ. Walter Brunner |
Klinik für Allgemein-, Viszeral-, Endokrin- und Transplantationschirurgie Kantonsspital St. Gallen, HOCH Health Ostschweiz, St. Gallen |
Ethikkommission Ostschweiz (EKOS) | 20.11.2025 | ||||||||
| 2025-02348 | SELECT-PF Clinical Survey Data Collection Plan | personal data/biological material | monocentric | Dr. Sven Knect | Medtronic Bakken Research Center B.V. |
Universitätsspital Basel, Basel |
Ethikkommission Nordwest- und Zentralschweiz EKNZ | 22.12.2025 | |||||||
| 2025-02347 | Outcomes of Patients Managed in a Newly Established Hypertension Clinic | personal data/biological material | monocentric | Dr. med. Federico Moccetti | Luzerner Kantonsspital |
Luzerner Kantonsspital, Luzern |
Ethikkommission Nordwest- und Zentralschweiz EKNZ | 25.11.2025 | |||||||
| 2025-02346 | Identification of Risk Factors for the Development of Pneumococcal Meningitis in Patients with Invasive Pneumococcal Disease: A Retrospective, Nested Case-Control Study | personal data/biological material | monocentric | PD Dr. med. Fabian Liechti | Inselspital, Bern University Hospital |
Inselspital, Bern University Hospital, Dpt. of General Internal Medicine, Bern |
Kantonale Ethikkommission Bern | 22.12.2025 | |||||||
| 2025-02345 | A Single Centre, Longitudinal, Observational Study to Assess the Evolution of Nystagmus from Child to Adulthood | non clinical, involving persons | monocentric | A | Melody Hedinger | Luzerner Kantonsspital |
Luzerner Kantosspital, Luzern |
Ethikkommission Nordwest- und Zentralschweiz EKNZ | 24.12.2025 | yes | |||||
| 2025-02339 | VITAKIDS – Vitamin status of Swiss children: what’s on the menu? | personal data/biological material | monocentric | Prof. Angéline Chatelan | Haute école de santé, HES-SO Genève |
Haute école de santé (HES-SO Genève), Carouge (Genève) |
Commission Cantonale d'éthique de la recherche Genève (CCER) | 07.01.2026 | |||||||
| 2025-02338 | Retrospective Analysis of Norovirus and Other Infectious Causes of Gastroenteritis | personal data/biological material | monocentric | PD Dr. Karoline Leuzinger | University Hospital Basel |
University Hospital Basel, Basel |
Ethikkommission Nordwest- und Zentralschweiz EKNZ | 17.12.2025 | |||||||
| 2025-02326 | A double-blind, randomized, placebo-controlled, two arm, phase II clinical trial in parallel groups to evaluate the efficacy and tolerability of a rectal treatment with budesonide suppositories compar More ... | clinical trial | drugs | phase 2 | multicentric | B | Dr. med. Franc Radovic | Dr. FALK PHARMA GmbH |
Universitätsspital Basel, Basel Kantonsspital Graubünden, Chur |
Ethikkommission Nordwest- und Zentralschweiz EKNZ | Kantonale Ethikkommission Zürich | 18.12.2025 | |||
| 2025-02323 | Daily Therapy Load During Inpatient Rehabilitation After Spinal Cord Injury – A Pilot Study | non clinical, involving persons | monocentric | A | Dr. sc. ETH Mario Widmer | Schweizer Paraplegiker-Forschung |
Swiss Paraplegic Research, Nottwil |
Ethikkommission Nordwest- und Zentralschweiz EKNZ | 15.12.2025 | ||||||
| 2025-02322 | Lifestyle Physical Activity Coaching in Inpatients Treated for Depression (PACINPAT+): Randomized Controlled Trial on Physical Activity, Depression and Quality of Life | clinical trial | other clinical trials | multicentric | A | Prof. Dr. Markus Gerber | Department für Sport, Bewegung und Gesundheit |
Department für Sport, Bewegung und Gesundheit, Basel Psychiatric Services Solothurn, Solothurn Sonnenhalde AG, Riehen |
Ethikkommission Nordwest- und Zentralschweiz EKNZ | Ethikkommission Nordwest- und Zentralschweiz EKNZ | 23.12.2025 | ||||
| 2025-02321 | The Swiss Vaccination Coverage Survey - Vaccination coverage of children aged 2, 8 and 16 years living in Switzerland | non clinical, involving persons | monocentric | A | Phung Lang | Epidemiology, Biostatistics and Prevention Institute, University of Zurich |
Epidemiology, Biostatistics and Prevention Institute, University of Zurich, Zurich |
Kantonale Ethikkommission Zürich | 18.12.2025 | yes | |||||
| 2025-02320 | Real world evaluation of AI based Auto-Segmentation in Radiotherapy: Assessing the Clinical Relevance and Need for Quality Assurance. | personal data/biological material | monocentric | Prof. Sarah Brueningk | Inselspital University Hospital Bern |
Inselspital University Hospital Bern, Bern |
Kantonale Ethikkommission Bern | 14.01.2026 | |||||||
| 2025-02319 | Assessing representativeness of trial cohorts for target populations: comparison of UKBB KIDS-STEP and ADEQUATE participants to non-participating children fulfilling eligibility criteria | personal data/biological material | monocentric | Prof Dr. med. Julia Bielicki | Universitäts-Kinderspital beider Basel |
University Children's Hospital Basel UKBB, Basel |
Ethikkommission Nordwest- und Zentralschweiz EKNZ | 17.12.2025 | |||||||
| 2025-02317 | Evolution of surgical management of non-small-cell lung cancer (NSCLC): a 10-year single-center experience | personal data/biological material | monocentric | Prof. Dr. med Michel Gonzalez | CHUV - Chirurgie Thoracique |
CHUV, Lausanne |
Commission cantonale d'Éthique de la Recherche sur l'être humain Vaud (CER-VD) | 27.11.2025 | |||||||
| 2025-02315 | ASPECTS in small vessel disease (SVD) – Is the ASPECTS score reliable in patients with large vessel occlusion and moderate to severe SVD? | personal data/biological material | monocentric | Dr. Dr. Tolga Dittrich | HOCH Cantonal Hospital St. Gallen |
Department of Neurology, HOCH Cantonal Hospital St. Gallen, St. Gallen |
Ethikkommission Ostschweiz (EKOS) | 13.11.2025 | |||||||