| BASEC ID | Project title | Type of project | Type of clinical trial | Study phase (clinical trials only) | multi- / monocentric | Category | Principal investigator | Sponsor | Investigational sites | Lead EC | Local EC(s) | Approval date | Minors | Study Ended | |
|---|---|---|---|---|---|---|---|---|---|---|---|---|---|---|---|
| 2023-01106 | The rescue pedicle screw as a freehand adjacent segment-sparing revision strategy for implant loosening - A technical note and comparative biomechanical study on human cadavers | deceased persons | monocentric | Prof. Dr. med. Mazda Farshad | Universitätsklinik Balgrist |
Universitätsklinik Balgrist, Zürich |
Kantonale Ethikkommission Zürich | 25.07.2023 | |||||||
| 2023-01105 | Psychotherapiewirksamkeit in einem Ambulatorium für Abhängigkeitserkrankungen | personal data/biological material | monocentric | Dr. Susanne Leiberg | Klinik im Hasel, Ambulatorium Lenzburg |
Klinik im Hasel, Lenzburg |
Ethikkommission Nordwest- und Zentralschweiz EKNZ | 30.08.2023 | |||||||
| 2023-01104 | 20190341- A Phase 3 multicenter, randomized, open label Study Evaluating Efficacy of Sotorasib Platinum Doublet Combination versus Pembrolizumab Platinum Doublet Combination as a Front-Line Therapy in More ... | clinical trial | drugs | phase 3 | multicentric | C | Prof Dr Med Sacha Rothschild | Amgen Switzerland AG |
Kantonsspital Baden, Baden Medizinische Universitätsklinik Kantonsspital Aarau, Aarau Universitaetsspital Basel, Basel Universitätsspital Zürich, Zuerich |
Ethikkommission Nordwest- und Zentralschweiz EKNZ | Ethikkommission Nordwest- und Zentralschweiz EKNZ, Kantonale Ethikkommission Zürich | 03.10.2023 | |||
| 2023-01103 | Detection of biomarkers in oral and oropharyngeal squamous cell carcinoma using breath analysis with respect to the oral microbiome | non clinical, involving persons | monocentric | A | Prof. Dr. med. Dr. med. dent. Harald Essig | University Hospital Zurich |
University Hospital Zurich, Zurich |
Kantonale Ethikkommission Zürich | 05.09.2023 | ||||||
| 2023-01102 | A Phase 3, Open-label, Randomized Study To Compare the Efficacy and Safety of Odronextamab (REGN1979), an Anti‑CD20 x Anti-CD3 Bispecific Antibody, Versus Investigator’s Choice in Previously Untreated More ... | clinical trial | drugs | phase 3 | multicentric | C | Dr. Fatime Kransiqi | Regeneron Pharmaceuticals, Inc. |
University Hospital Basel, Medical Oncology, Petersgraben 4, Basel Inselspital / Bern University Hospital, Medizinische Onkologie, Freiburgstrasse 41, Bern Kantonsspital Baden, Im Ergel 1, 5404 Baden, More ... |
Ethikkommission Nordwest- und Zentralschweiz EKNZ | Ethikkommission Nordwest- und Zentralschweiz EKNZ, Ethikkommission Ostschweiz (EKOS), Kantonale Ethikkommission Bern, Kantonale Ethikkommission Zürich | 29.11.2023 | |||
| 2023-01101 | Analysis of Genetic Testing for Predisposition to Breast and Ovarian Cancers in a High-Risk Population, Masterarbeit | personal data/biological material | monocentric | Prof. Dr. med. Cornelia Leo | Kantonsspital Baden |
Kantonsspital Baden, interdisziplinäres Brustzentrum, Baden |
Ethikkommission Nordwest- und Zentralschweiz EKNZ | 30.06.2023 | |||||||
| 2023-01100 | Feasibility of virtual reality assistance in prostate biopsy under local anesthesia. | clinical trial | other clinical trials | monocentric | A | Dr Daniel Benamran | HUG |
Hôpitaux Universitaires de Genève, Genève |
Commission Cantonale d'éthique de la recherche Genève (CCER) | 06.11.2023 | |||||
| 2023-01099 | Les besoins éducatifs particuliers dans les études supérieures | non clinical, involving persons | monocentric | A | Murielle Martin | Haute école de travail social et |
HETSL, Lausanne |
Commission cantonale d'Éthique de la Recherche sur l'être humain Vaud (CER-VD) | 07.07.2023 | ||||||
| 2023-01098 | Pilot Study exploring reliability of Ocular Impedance Recording | non clinical, involving persons | monocentric | A | Prof. Dr. Daniela Nosch | FHNW |
FHNW, Institut für Optometrie, 4600 Olten |
Ethikkommission Nordwest- und Zentralschweiz EKNZ | 13.07.2023 | ||||||
| 2023-01096 | High-throughput identification of disrupted molecular pathways in schizophrenia patients. | deceased persons | monocentric | Pr. Denis Jabaudon | UNIGE |
UNIGE, Geneva |
Commission Cantonale d'éthique de la recherche Genève (CCER) | 06.07.2023 | |||||||
| 2023-01091 | Zurich Lymphregistry | non clinical, involving persons | monocentric | A | Prof. Nicole Lindenblatt | University Hospital Zurich |
University Hospital Zurich, Zurich |
Kantonale Ethikkommission Zürich | 06.10.2023 | ||||||
| 2023-01089 | A Phase Ib open-label, multi-center, dose escalation trial of BI 764532 given as monotherapy administered by repeated intravenous infusions in patients with glioma expressing DLL3 | clinical trial | drugs | phase 1/2 | multicentric | C | Professor Patrick Roth | Boehringer Ingelheim RCV GmbH & Co KG |
University Hospital Zurich, Zurich Kantonsspital Aarau, Aarau Lausanne University Hospital Center, Lausanne |
Kantonale Ethikkommission Zürich | Ethikkommission Nordwest- und Zentralschweiz EKNZ, Commission cantonale d'Éthique de la Recherche sur l'être humain Vaud (CER-VD) | 29.09.2023 | |||
| 2023-01088 | SAFIR-E une intervention familiale interprofessionnelle pour les familles des patients atteints d’une lésion cérébrale acquise : un projet d’implantation | non clinical, involving persons | monocentric | A | Monsieur Dionys Rutz | CHUV - DNC - Physiothérapie |
CHUV, Lausanne |
Commission cantonale d'Éthique de la Recherche sur l'être humain Vaud (CER-VD) | 11.08.2023 | ||||||
| 2023-01087 | Defibrillation in accidental hypothermia: a retrospective study of the International Hypothermia Registry | personal data/biological material | monocentric | Evelien Cools | Hôpitaux Universitaires Genève |
Hôpitaux Universitaires Genève, Switzerland |
Commission Cantonale d'éthique de la recherche Genève (CCER) | 13.09.2023 | |||||||
| 2023-01086 | Anaesthesiological Care for Thrombectomy in Stroke (ACT in Stroke): - A Randomized Controlled Multicentre Study | clinical trial | other clinical trials | monocentric | A | Prof Marios Psychogios | Klinikum rechts der Isar der Technischen Universität München |
Universiätsspital Basel, Basel |
Ethikkommission Nordwest- und Zentralschweiz EKNZ | 20.07.2023 | |||||
| 2023-01085 | REVACO: Vaccination delay during the COVID-19 pandemic in children | non clinical, involving persons | monocentric | A | Dr. Pierre-Alex Crisinel | CHUV - DFME - BH11-967 |
CHUV, Lausanne |
Commission cantonale d'Éthique de la Recherche sur l'être humain Vaud (CER-VD) | 31.07.2023 | yes | |||||
| 2023-01084 | Effect of vitamin D3, omega-3s and a simple strength training exercise program on indices of bone strength in European older adults: a secondary analysis of the DO-HEALTH randomized controlled trial. | personal data/biological material | monocentric | Prof. Dr. med., DrPH Heike A. Bischoff-Ferrari | Zentrum Alter und Mobilität, Universität Zürich |
Zentrum Alter und Mobilität, Universität Zürich, Zurich |
Kantonale Ethikkommission Zürich | 03.11.2023 | |||||||
| 2023-01083 | Spinal injections in lumbosacral epidural lipomatosis | non clinical, involving persons | monocentric | A | PD Dr. med. Thorsten Jentzsch | Balgrist University Hospital |
Balgrist University Hospital, Zürich |
Kantonale Ethikkommission Zürich | 23.02.2024 | ||||||
| 2023-01082 | Beobachtungsstudie neuroradiologischer Untersuchungen hämorrhagischer und nicht-hämorrhagischer vaskulärer Läsionen. | personal data/biological material | monocentric | PD Dr. Tilman Schubert | University Hospital Zürich |
University Hospital Zurich, Zürich |
Kantonale Ethikkommission Zürich | 05.09.2023 | |||||||
| 2023-01081 | Inflammatory memory signatures in nasal polyposis | non clinical, involving persons | monocentric | A | Dr. Antoine Reinhard | CHUV |
CHUV, Lausanne |
Commission cantonale d'Éthique de la Recherche sur l'être humain Vaud (CER-VD) | 13.09.2023 | ||||||