| BASEC ID | Project title | Type of project | Type of clinical trial | Study phase (clinical trials only) | multi- / monocentric | Category | Principal investigator | Sponsor | Investigational sites | Lead EC | Local EC(s) | Approval date | Minors | Study Ended | |
|---|---|---|---|---|---|---|---|---|---|---|---|---|---|---|---|
| 2016-02022 | Feasibility and evaluation of of checkpoint inhibitors (PD-L1, LAG-3, BTLA and TIM-3) immunocytochemical expression in cytological and/or histological specimens from lung and thyroid carcinomas | personal data/biological material | monocentric | Pr. Massimo Bongiovanni |
Synlab Pathology /Argot Lab, Lausanne |
Commission cantonale d'Éthique de la Recherche sur l'être humain Vaud (CER-VD) | 23.01.2017 | Study has ended | |||||||
| 2016-02021 | Posttransplant outcome and risk factors for recurrence in Swiss kidney transplant recipients with IgA nephropathy - The IgAN recurrence study | personal data/biological material | multicentric | PD Dr. Min Jeong Kim | University Hospital Basel |
Klink für Transplantationsimmunologie und Nephrologie, Universitätsspital Basel, Basel Universitätsklinik für Nephrologie, Hypertonie und Klinische Pharmakologie; Inselspital Bern, Bern Département de More ... |
Ethikkommission Nordwest- und Zentralschweiz EKNZ | Ethikkommission Ostschweiz (EKOS), Kantonale Ethikkommission Bern, Kantonale Ethikkommission Zürich, Commission cantonale d'Éthique de la Recherche sur l'être humain Vaud (CER-VD), Commission Cantonal More ... | 27.04.2017 | ||||||
| 2016-02020 | Traitement par cryothérapie des métastases ganglionnaires | personal data/biological material | monocentric | Professor, Alban Denys | CHUV |
CHUV , Lausanne |
Commission cantonale d'Éthique de la Recherche sur l'être humain Vaud (CER-VD) | 30.01.2017 | |||||||
| 2016-02019 | Atteinte physique et harcèlement chez les jeunes | non clinical, involving persons | monocentric | A | Dr Anthony DeBuys-Roessingh | DMCP - CHUV |
CHUV, Lausanne |
Commission cantonale d'Éthique de la Recherche sur l'être humain Vaud (CER-VD) | 03.05.2017 | yes | |||||
| 2016-02017 | Result of distal bypasses with arterial allografts | personal data/biological material | monocentric | Mrs. Sophie Masmejan | CHUV |
University Hospital of Lausanne, Lausanne |
Commission cantonale d'Éthique de la Recherche sur l'être humain Vaud (CER-VD) | 05.07.2017 | |||||||
| 2016-02015 | Non-interventional, multicenter, multinational venous stent study for the treatment of the post-thrombotic syndrome with common iliac vein compression | non clinical, involving persons | multicentric | A | Dr. Marc Schindewolf | optimed Medizinische Instrumente GmbH |
INSELSPITAL, Universitätsspital Bern, Bern UniversitätsSpital Zürich, Zürich |
Kantonale Ethikkommission Bern | Kantonale Ethikkommission Zürich | 14.12.2016 | Study has ended | ||||
| 2016-02014 | Evaluation of Ablation Index and VISITAG™ use for Pulmonary Vein Isolation (PVI) in Patients with Paroxysmal Atrial Fibrillation (PAF) | clinical trial | medical devices | monocentric | A | Dr. Richard Kobza | Biosense Webster, Inc. |
Luzerner Kantonsspital, Luzern |
Ethikkommission Nordwest- und Zentralschweiz EKNZ | 28.03.2017 | Study has ended | ||||
| 2016-02013 | Utilizing fresh tumor explants for RNA sequencing and establishment of ex vivo models for the assessment of the activity of cancer immunotherapy agents | non clinical, involving persons | multicentric | A | Prof. Dr. med. Christoph Renner | Roche Glycart AG |
Klinik Hirslanden, Zürich Hirslanden Klinik St. Anna, 6006 Luzern |
Kantonale Ethikkommission Zürich | Ethikkommission Nordwest- und Zentralschweiz EKNZ | 12.01.2017 | |||||
| 2016-02012 |
Preservation of kidney function in kidney transplant recipients by alkali therapy (Preserve-Transplant Study): a multi-center randomized single-blind placebo- controlled trial |
clinical trial | drugs | phase 4 | multicentric | B | Prof. Wagner | Universität Zürich |
Universität Zürich, Zürich Klinik für Nephrologie, Inselspital, Bern HUG (University Hospital Geneva), Genf |
Kantonale Ethikkommission Zürich | Kantonale Ethikkommission Bern, Commission Cantonale d'éthique de la recherche Genève (CCER) | 05.11.2021 | |||
| 2016-02011 |
Clinical outcomes of patients with relapsed malignant mesothelioma treated with Pembrolizumab in daily practice - a Swiss multicentre retrospective study |
personal data/biological material | multicentric | Dr. med. Yannis Metaxas | Kantonsspital Graubünden |
Kantonsspital Graubünden, Chur Universitätsklinik für Medizinische Onkologie, Inselspital Bern, Bern Universitätsspital Basel, Basel Onkologiezentrum - Solothurner Spitäler, Olten Medizinische Onkolog More ... |
Kantonale Ethikkommission Zürich | Ethikkommission Nordwest- und Zentralschweiz EKNZ, Ethikkommission Ostschweiz (EKOS), Kantonale Ethikkommission Bern, Kantonale Ethikkommission Zürich, Commission cantonale d'Éthique de la Recherche s More ... | 03.03.2017 | ||||||
| 2016-02010 | Embodiment of semantic representations in bilinguals | non clinical, involving persons | monocentric | A | Prof. Dr. med. Jean-Marie Annoni |
LCNS, Université de Fribourg, Faculté des Sciences, Département de Médecine, Neurologie, Fribourg |
Commission cantonale d'Éthique de la Recherche sur l'être humain Vaud (CER-VD) | 31.01.2017 | |||||||
| 2016-02009 | The p3 concept in the treatment of delayed unions and non-unions: A retrospective case series | personal data/biological material | monocentric | Professor Dr. med. Norbert Suhm |
Department of Orthopaedics and Traumatology University Hospital of Basel, Basel |
Ethikkommission Nordwest- und Zentralschweiz EKNZ | 24.04.2017 | ||||||||
| 2016-02008 | A retrospective study using already collected biological samples and clinical data in patients treated with checkpoint inhibitors against solid tumors: “Discovering gene signatures that could predict More ... | personal data/biological material | monocentric | Prof. George Coukos | CHUV, Oncology |
CHUV, Lausanne |
Commission cantonale d'Éthique de la Recherche sur l'être humain Vaud (CER-VD) | 30.01.2017 | |||||||
| 2016-02007 |
A Phase III, Randomized, Open Label Trial of Nivolumab in combination with Ipilimumab versus Pemetrexed with Cisplatin or Carboplatin as First Line Therapy in unresectable Pleural Mesothelioma (Check More ... |
clinical trial | drugs | phase 3 | multicentric | C | Prof. Dr., Peters, Solange | Bristol-Myers Squibb International Corporation |
Centre Hospitalier Universitaire Vaudois (CHUV), Centre du Cancer Lausanne, Lausanne INSELSPITAL, Universitätsspital Bern, Universitätsklinik für Medizinische Onkologie, Freiburgstrasse 10, 3010 Bern More ... |
Commission cantonale d'Éthique de la Recherche sur l'être humain Vaud (CER-VD) | Kantonale Ethikkommission Bern, Kantonale Ethikkommission Zürich | 19.05.2017 | |||
| 2016-02006 | Early Mortality and Long-Term Survival after Lung Transplantation for Idiopathic Pulmonary Fibrosis | personal data/biological material | monocentric | PD Dr. med. Ilhan Inci |
UniveristätsSpital Zürich , Zürich |
Kantonale Ethikkommission Zürich | 22.02.2017 | ||||||||
| 2016-02004 | Comparative pharmacokinetic profile of two new different formulations of S-adenosyl-L-methionine as food supplement in healthy volunteers | clinical trial | other clinical trials | monocentric | A | Milko Radicioni, MD | Gnosis S.p.A. |
CROSS Research S.A., Arzo |
Comitato etico cantonale Ticino | 13.12.2016 | Study has ended | ||||
| 2016-02003 |
Impact of perioperative maintenance or interruption of low-dose Aspirin on recurrence rate and thrombotic Events after burr-hole drainage of chronic subdural hematoma: a randomized, placebocontrolle More ... |
clinical trial | drugs | phase 4 | multicentric | B | Dr. Jehuda Soleman | University Hospital Basle |
University Hospital Basel, Basel Neurochirurgische Klinik, Inselspital Bern, Bern Luzerner Kantonsspital, Luzern Kantonsspital Aarau, Aarau Kantonsspital St Gallen, St Gallen Kantonsspital Graubünden, More ... |
Ethikkommission Nordwest- und Zentralschweiz EKNZ | Ethikkommission Nordwest- und Zentralschweiz EKNZ, Ethikkommission Ostschweiz (EKOS), Kantonale Ethikkommission Bern, Kantonale Ethikkommission Zürich | 05.04.2017 | |||
| 2016-02002 | LUKS-Leads Register | personal data/biological material | monocentric | PD Dr. med. Richard Kobza | Luzerner Kantonsspital |
Luzerner Kantonsspital, Luzern |
Ethikkommission Nordwest- und Zentralschweiz EKNZ | 02.01.2017 | |||||||
| 2016-02001 | Effect of Augmented Reality Exergaming on Physical Activity in Overweight Adults (Active Through Augmented Reality – AVATAR) | non clinical, involving persons | monocentric | A | Prof. Dr. Arno Schmidt-Trucksäss | University of Basel |
University of Basel, Basel |
Ethikkommission Nordwest- und Zentralschweiz EKNZ | 11.01.2017 | ||||||
| 2016-02000 | Effects of three single oral doses of trazodone on the QTc interval duration in healthy volunteers | clinical trial | drugs | phase 1 | monocentric | C | MD Milko Radicioni | ACRAF S.p.A. |
CROSS Research S.A., Arzo |
Comitato etico cantonale Ticino | 13.12.2016 | Study has ended | |||