| BASEC ID | Project title | Type of project | Type of clinical trial | Study phase (clinical trials only) | multi- / monocentric | Category | Principal investigator | Sponsor | Investigational sites | Lead EC | Local EC(s) | Approval date | Minors | Study Ended | |
|---|---|---|---|---|---|---|---|---|---|---|---|---|---|---|---|
| 2019-01162 |
PROPHETIC Studie Prognostication of Outcome in Patients with Out-of Hospital Cardiac Arrest Hospitalized in Intensive Care |
non clinical, involving persons | multicentric | A | Prof. Sabina Hunziker | University Hospital Basel |
Universitätsspital Basel, Basel Kantonsspital Aarau, Aarau |
Ethikkommission Nordwest- und Zentralschweiz EKNZ | Ethikkommission Nordwest- und Zentralschweiz EKNZ | 07.10.2019 | |||||
| 2019-01161 | FEASIBILITY OF AN INTERACTIVE TABLET-BASED EXERCISE PROGRAM FOR PEOPLE WITH CHRONICAL DISEASES | clinical trial | other clinical trials | monocentric | A | Mr. Damiano Zemp | EOC |
EOC, Mendrisio |
Comitato etico cantonale Ticino | 16.08.2019 | Study has ended | ||||
| 2019-01160 |
Whole-brain irradiation with hippocampal sparing and dose escalation on metastases: neurocognitive testing and biological imaging A phase II prospective randomized multicentre study |
clinical trial | other clinical trials | multicentric | B | Prof. Dr. med. Matthias Guckenberger | Klinik für Radio-Onkologie |
UniversitätsSpital Zürich, Zürich Klinik Hirslanden, 8032 Zürich |
Kantonale Ethikkommission Zürich | Kantonale Ethikkommission Zürich | 04.11.2019 | Study has ended | |||
| 2019-01158 | The effect of Comorbidity on Outcome in Patients Hospitalized For Acute Heart Failure in Lausanne (LAU-AHF) | personal data/biological material | monocentric | Professor Dr. Roger Hullin | CHUV - BU44-2208 |
Centre Hospitalier Universitaire Vaudois, Lausanne |
Commission cantonale d'Éthique de la Recherche sur l'être humain Vaud (CER-VD) | 18.07.2019 | Study has ended | ||||||
| 2019-01157 |
CNIS793X2101 - A phase I/Ib, open-label, multi-center dose escalation study of NIS793 in combination with PDR001 in adult patients with advanced malignancies |
clinical trial | drugs | phase 1 | monocentric | C | Prof. Dr. med. Markus Jörger | Novartis Pharma Schweiz AG |
Kantonsspital, St. Gallen |
Ethikkommission Ostschweiz (EKOS) | 09.08.2019 | Study has ended | |||
| 2019-01156 | Urgent large bowel decompression: is Caecostomy a valid alternative to loop colostomy? | personal data/biological material | monocentric | Dr. Michele Arigoni | Ospedale Reginale di Locarno |
Ospedale Regionale di Locarno, Locarno |
Comitato etico cantonale Ticino | 09.07.2019 | |||||||
| 2019-01155 | Bacterial infections in patients with cirrhosis: Impact of an antibiotic stewardship program on in-hospital stay and mortality | personal data/biological material | monocentric | Prof. Annalisa Berzigotti | UVCM Hepatologie |
UVCM Hepatologie, Bern |
Kantonale Ethikkommission Bern | 19.12.2019 | Study has ended | ||||||
| 2019-01154 | 3D primary cell culture as a new model for precision medicine in gastro-entero-pancreatic neuroendocrine neoplasms (GEP-NEN) | personal data/biological material | multicentric | Prof. Aurel Perren | Institut für Pathologie, Universität Bern |
Institut für Pathologie, Universität Bern, Bern University of Basel, Basel HÔPITAUX UNIVERSITAIRES GENÈVE, Geneva CHUV, Lausanne University Hospital Zurich, Zurich |
Kantonale Ethikkommission Bern | Ethikkommission Nordwest- und Zentralschweiz EKNZ, Kantonale Ethikkommission Zürich, Commission cantonale d'Éthique de la Recherche sur l'être humain Vaud (CER-VD), Commission Cantonale d'éthique de l More ... | 02.12.2019 | ||||||
| 2019-01153 | Human Pegivirus and immune response after allogeneic stem cell transplantation: other than a commensal virus? | personal data/biological material | monocentric | Dr Diem-Lan Vu Cantero | Service of infectious diseases |
Geneva University Hospitals, Geneva |
Commission Cantonale d'éthique de la recherche Genève (CCER) | 09.07.2019 | |||||||
| 2019-01152 | TRI0209 – Single-cell dissection of the cellular ecosystem in hepatocellular carcinoma | personal data/biological material | monocentric | Dr Guglielmo Roma | Novartis Pharma AG - NIBR |
Novartis Pharma AG - NIBR, Basel |
Ethikkommission Nordwest- und Zentralschweiz EKNZ | 07.08.2019 | |||||||
| 2019-01151 | Patientenselektion und Langzeitverlauf bei Patienten mit einer Pace & Ablate Strategie zur interventionellen Frequenzkontrolle bei symptomatischem permanenten Vorhofflimmern – eine retrospektive multi More ... | personal data/biological material | multicentric | Dr. med. Nikola Kozhuharov | Universitätsklinik für Kardiologie, Inselspital |
Universitätsklinik für Kardiologie, Inselspital, Bern Universitätsspital Basel, Kardiologie, Basel Universitätsspital Genf, Genf |
Kantonale Ethikkommission Bern | Ethikkommission Nordwest- und Zentralschweiz EKNZ, Commission Cantonale d'éthique de la recherche Genève (CCER) | 11.09.2019 | ||||||
| 2019-01150 |
DANTE FLOT8 - A randomized, open-label Phase II/III efficacy and safety study of atezolizumab in combination with FLOT versus FLOT alone in patients with gastric cancer and adenocarcinoma of the oeso More ... |
clinical trial | drugs | phase 3 | multicentric | B | Dr. med. Alexander Siebenhüner | Frankfurter Institut für Klinische Krebsforschung IKF GmbH |
Klinik für Hämatologie und Onkologie Hirslanden Zürich AG, Zürich Spital STS AG, Thun Inselspital, Bern Kantonsspital Baden, Brugg und Baden Kantonsspital Olten, Olten St. Claraspital, Basel Tumor Zen More ... |
Kantonale Ethikkommission Zürich | Ethikkommission Nordwest- und Zentralschweiz EKNZ, Ethikkommission Ostschweiz (EKOS), Kantonale Ethikkommission Bern, Kantonale Ethikkommission Zürich, Commission cantonale d'Éthique de la Recherche s More ... | 19.12.2019 | |||
| 2019-01149 | Empirical comparison of different prediction methods to common problems in emergency medicine | personal data/biological material | monocentric | PD Dr. Wolf Hautz | Inselspital Bern |
Universitäres Notfallzentrum, Inselspital Bern, Bern |
Kantonale Ethikkommission Bern | 13.08.2019 | |||||||
| 2019-01148 | Evaluation of the satisfaction and tolerance of intra uterin device in women under 25 years | non clinical, involving persons | multicentric | A | Dre Martine Jacot-Guillarmod | CHUV - DFME |
CHUV, Lausanne Consultation de santé sexuelle -planning familial de la fondation PROFA (CSS), Lausanne |
Commission cantonale d'Éthique de la Recherche sur l'être humain Vaud (CER-VD) | Commission cantonale d'Éthique de la Recherche sur l'être humain Vaud (CER-VD) | 20.11.2019 | yes | Study has ended | |||
| 2019-01147 | Determination of anatomical characteristics to prevent conversion in posterior retroperitoneal adrenalectomy. | personal data/biological material | monocentric | PD Dr. med. Christian Nebiker |
Kantonsspital Aarau, Aarau |
Ethikkommission Nordwest- und Zentralschweiz EKNZ | 29.07.2019 | ||||||||
| 2019-01146 | Functional consequences of genetic variations in endometriosis | personal data/biological material | monocentric | Professor Michael Mueller | Institute for Molecular Bioscience |
Frauenklinik Inselspital, Bern |
Kantonale Ethikkommission Bern | 06.11.2019 | |||||||
| 2019-01145 | CSL300_3001 (former VKTX01) : A PIVOTAL PHASE 3 TRIAL TO EVALUATE THE SAFETY AND EFFICACY OF CLAZAKIZUMAB FOR THE TREATMENT OF CHRONIC ACTIVE ANTIBODY MEDIATED REJECTION IN KIDNEY TRANSPLANT RECIPIENT More ... | clinical trial | drugs | phase 3 | multicentric | C | Prof. Dr. Thomas Müller | CSL Behring LLC (CSLB) |
UniversitätsSpital Zürich, Zürich Department of Nephrology and Hypertension, University of Bern, Inselspital, CH – 3010 Bern |
Kantonale Ethikkommission Zürich | Kantonale Ethikkommission Bern | 03.12.2019 | Study has ended | ||
| 2019-01144 | Bioengineering a fully patterned human stomach-on-a-chip | non clinical, involving persons | monocentric | A | Dr. François Gorostidi | EPFL |
CHUV, Lausanne |
Commission cantonale d'Éthique de la Recherche sur l'être humain Vaud (CER-VD) | 14.01.2020 | ||||||
| 2019-01143 | Suprafascial vancomycin powder for prevention of surgical site infections after instrumented posterior spinal fusion: A randomized controlled phase-II trial | clinical trial | drugs | phase 2 | multicentric | B | PD Dr. med. Ralph Schär | Universitätsklinik für Neurochirurgie |
Universitätsklinik für Neurochirurgie, Bern Lindenhofspital Bern, Bern Spitalzentrum Biel, Biel Inselspital, Universitätsklinik für Orthopädie, Bern Hirslanden Klinik St. Anna, Klinik für Neuro- und More ... |
Kantonale Ethikkommission Bern | Ethikkommission Nordwest- und Zentralschweiz EKNZ, Ethikkommission Ostschweiz (EKOS), Kantonale Ethikkommission Bern, Kantonale Ethikkommission Zürich | 17.11.2020 | |||
| 2019-01142 | Langzeitwirksamkeit der Erhaltungs-Elektrokonvulsionstherapie (EKT) bei Patienten mit depressivem Syndrom und Wirksamkeit der EKT-Behandlung der Katatonie | personal data/biological material | monocentric | Dr. med. Dr. phil. Tobias Bracht | Universitäre Psychiatrische Dienste Bern |
Universitäre Psychiatrische Dienste Bern, Bern |
Kantonale Ethikkommission Bern | 21.01.2020 | |||||||