| BASEC ID | Project title | Type of project | Type of clinical trial | Study phase (clinical trials only) | multi- / monocentric | Category | Principal investigator | Sponsor | Investigational sites | Lead EC | Local EC(s) | Approval date | Minors | Study Ended | |
|---|---|---|---|---|---|---|---|---|---|---|---|---|---|---|---|
| 2016-01497 | Untersuchung prädiktiver und prognostischer Biomarker in Hirnmetastasen von Lungenkarzinomen und im Vergleich mit dem Primärtumor | personal data/biological material | monocentric | Sabina Berezowska | Institut für Pathologie der Universität Bern |
Institut für Pathologie, Universität Bern, Bern |
Kantonale Ethikkommission Bern | 21.09.2016 | |||||||
| 2016-01496 | Analyse der molekularen Mikroumgebung immunogener solider Tumoren | personal data/biological material | monocentric | PD Dr. med. Kirsten Mertz | Kantonsspital Baselland |
Kantonsspital Baselland, Institut für Pathologie, Liestal |
Ethikkommission Nordwest- und Zentralschweiz EKNZ | 07.11.2016 | |||||||
| 2016-01495 | Cell spillage after contained power morcellation using a specially designed in-bag system for laparoscopic myomectomy: a prospective cohort pilot study. | non clinical, involving persons | monocentric | A | Shahzia Lambat Emery | HUG |
HUG, Geneva |
Commission Cantonale d'éthique de la recherche Genève (CCER) | 23.02.2017 | Study has ended | |||||
| 2016-01494 | Lumacaftor-Ivacaftor combination therapy in Phe508del homozygous Cystic Fibrosis (CF) patients with endstage lung disease | personal data/biological material | monocentric | PD Dr. med. Christian Benden | Department of Pneumology |
Division of Pulmonology, University Hospital Zurich, Zurich |
Kantonale Ethikkommission Zürich | 20.12.2016 | |||||||
| 2016-01493 | Entyvio (vedolizumab) Long-term safety study: An international observational prospective cohort study comparing vedolizumab to other biologic agents in patients with ulcerative colitis or Crohn`s Dise More ... | non clinical, involving persons | multicentric | A | Luc Biedermann | Takeda Development Centre Europe Ltd. |
Division of Gastroenterology & Hepatology, University Hospital Zurich, Zurich Inselspital Bern, Bern Gastroenterologische Praxis Balsiger, Seibold & Partner, Bremgartenstrasse 119, CH-3012 Bern Kanto More ... |
Kantonale Ethikkommission Zürich | Ethikkommission Ostschweiz (EKOS), Kantonale Ethikkommission Bern | 20.02.2018 | Study has ended | ||||
| 2016-01492 | A Phase III Double-blind, Randomized, Placebo-Controlled Study assessing the Efficacy, Safety and Tolerability of Idebenone in Patients with Duchenne Muscular Dystrophy Receiving Glucocorticoid Steroi More ... | clinical trial | drugs | phase 3 | monocentric | C | Dr. Andrea Klein | Santhera Pharmaceuticals (Switzerland) Limited |
Center for neuromuscular disorders, Universitäts-Kinderspital beider Basel (UKBB), Basel |
Ethikkommission Nordwest- und Zentralschweiz EKNZ | 08.11.2016 | Study has ended | |||
| 2016-01491 | Combining EUropean Registry data to investigate efficacy and toxicity of TNF inhibitor mOnotherapy versus combination therapy with methotrexate in Psoriatic Arthritis – EUROMPA | personal data/biological material | monocentric | Prof Dr Burkhard Möller | Swiss Clinical Quality Management in Rheumatic Diseases |
Inselpital , Bern |
Kantonale Ethikkommission Bern | 17.11.2016 | |||||||
| 2016-01490 | DAPHNE study: Real-Life Observational Study to Evaluate the Impact of the CYP3A4/5/7 and P-gp Pharmacogenetics on the Efficacy and Safety of the Direct Oral Anticoagulants Rivaroxaban and Apixaban in More ... | non clinical, involving persons | monocentric | A | Victoria Rollason | Hôpitaux Universitaires de Genève |
Hôpitaux Universitaires de Genève, Geneva |
Commission Cantonale d'éthique de la recherche Genève (CCER) | 25.01.2017 | Study has ended | |||||
| 2016-01489 | Observatoire Romand des Tentatives de Suicide | non clinical, involving persons | multicentric | A | Dr Laurent Michaud | CHUV |
CHUV, Lausanne HUG, Genève HUG, Genève CNP, Neuchâtel, La-Chaux-de-Fonds Hôpital du Valais, Sion |
Commission cantonale d'Éthique de la Recherche sur l'être humain Vaud (CER-VD) | Commission cantonale d'Éthique de la Recherche sur l'être humain Vaud (CER-VD), Commission Cantonale d'éthique de la recherche Genève (CCER) | 27.10.2016 | yes | ||||
| 2016-01488 | Dipeptidyl peptidase-IV inhibitors, a risk factor for development of bullous pemphigoid?: A retrospective multicenter analysis in Switzerland and France | personal data/biological material | monocentric | Dr. med. et phil. Laurence FELDMEYER |
Universitätsklinik für Dermatologie; Inselspital; Universitätsspital Bern, Bern |
Kantonale Ethikkommission Bern | 01.12.2016 | ||||||||
| 2016-01487 | A Randomized phase III trial comparing conventional-dose chemotherapy using paclitaxel, ifosfamide, and cisplatin (TIP) with high dose chemotherapy using mobilizing paclitaxel plus ifosfamide followed More ... | clinical trial | drugs | phase 3 | multicentric | B | Dr Christian Britschgi | European Organization for Research and Treatment of Cancer |
UniversitaetsSpital Zurich, Zurich Inselspital, Bern Hôpitaux universitaires de Genève, 1211 Genève |
Kantonale Ethikkommission Zürich | Kantonale Ethikkommission Bern, Commission Cantonale d'éthique de la recherche Genève (CCER) | 22.05.2017 | |||
| 2016-01486 | Influence de l’anesthésie générale sur la mesure de la pression intracompartimentale dans le syndrome des loges | non clinical, involving persons | monocentric | B | Dr Benoît Borner | HUG |
HUG, Genève |
Commission Cantonale d'éthique de la recherche Genève (CCER) | 17.12.2020 | yes | |||||
| 2016-01485 | Adaptierung eines Instruments und Messung nicht-motorischer Veränderungen infolge tiefer Hirnstimulation von Parkinson Patienten | non clinical, involving persons | monocentric | A | Dr. Christian Ineichen | Universitätsspital Zürich |
University Hospital Zurich, Zurich |
Kantonale Ethikkommission Zürich | 05.04.2017 | ||||||
| 2016-01484 | Comparison of vertical right axillary mini-thoracotomy versus median sternotomy for correction of congenital heart defects | personal data/biological material | monocentric | Prof. Dr. med. Alexander Kadner | Center of Congenital Heart Disease, Department of Cardio-Vascular Surgery, Inselspital Bern |
Inselspital, Bern |
Kantonale Ethikkommission Bern | 26.10.2016 | |||||||
| 2016-01483 | Impact of flash glucose monitoring (FGM) on the management of type 1 diabetes in children and adolescents. A retrospective study. | personal data/biological material | monocentric | PD Dr. med. PhD Gabor Szinnai | Universitäts-Kinderspital beider Basel |
Universitäts-Kinderspital beider Basel, Basel |
Ethikkommission Nordwest- und Zentralschweiz EKNZ | 24.01.2017 | |||||||
| 2016-01482 | Refractive Outcome and Optimization of IOL-Constants after Implantation of the Precisight® Intraocular Lens. | clinical trial | medical devices | monocentric | C | Dr. Sylvain Roy | InfiniteVision Optics |
Genolier - Swiss Visio Network, Lausanne |
Commission cantonale d'Éthique de la Recherche sur l'être humain Vaud (CER-VD) | 13.12.2016 | Study has ended | ||||
| 2016-01481 | ARIADNE - CLCZ696B3401: Assessment of Real LIfe cAre – Describing EuropeaN Heart FailurE Management | personal data/biological material | multicentric | Dr. med. Matthias Paul | Novartis Pharma Schweiz AG |
Kantonsspital Luzern / Herzzentrum, Luzern Kantonsspital Baselland, Liestal Cabinet Dr. med. Saed Burgan, Geneva Kantonsspital Frauenfeld, Frauenfeld Cabinet Dr. Stéphane Chevallier , Yverdon-les-Bain More ... |
Ethikkommission Nordwest- und Zentralschweiz EKNZ | Ethikkommission Nordwest- und Zentralschweiz EKNZ, Ethikkommission Ostschweiz (EKOS), Kantonale Ethikkommission Zürich, Commission cantonale d'Éthique de la Recherche sur l'être humain Vaud (CER-VD), More ... | 07.11.2016 | Study has ended | |||||
| 2016-01480 | Validation de la version française enrichie accessibilisée et informatisée du test TICPV (Test of Interpersonal Competence and Personal Vulnerability,Wilson et al., 1996/2011) | non clinical, involving persons | multicentric | A | Prof. Geneviève Petitpierre | Université de Fribourg |
Université de Fribourg, Fribourg Service des spécialités psychiatriques (UPDM), Genève |
Commission cantonale d'Éthique de la Recherche sur l'être humain Vaud (CER-VD) | Commission Cantonale d'éthique de la recherche Genève (CCER) | 06.02.2017 | |||||
| 2016-01479 | COMB157G2301 - A randomized, double-blind, double-dummy, parallel-group study comparing the efficacy and safety of ofatumumab versus teriflunomide in patients with relapsing multiple sclerosis | clinical trial | drugs | phase 3 | multicentric | C | Prof. Dr. med. Tobias Derfuss | Novartis Pharma Schweiz AG |
Universitätsspital, Basel Luzerner Kantonsspital, Luzern |
Ethikkommission Nordwest- und Zentralschweiz EKNZ | Ethikkommission Nordwest- und Zentralschweiz EKNZ | 29.11.2016 | Study has ended | ||
| 2016-01477 | Obstetrical and epidemiological factors that influence symptoms and symptoms´ severity after obstetric anal sphincter injury | personal data/biological material | monocentric | Dr. med. Tilemachos Kavvadias |
University Hospital Basel , Basel |
Ethikkommission Nordwest- und Zentralschweiz EKNZ | 28.09.2016 | ||||||||