| BASEC ID | Project title | Type of project | Type of clinical trial | Study phase (clinical trials only) | multi- / monocentric | Category | Principal investigator | Sponsor | Investigational sites | Lead EC | Local EC(s) | Approval date | Minors | Study Ended | |
|---|---|---|---|---|---|---|---|---|---|---|---|---|---|---|---|
| 2018-00553 | Outcome von Patienten nach Doppelklappeneingriffen am USB (Doktorarbeit) | personal data/biological material | monocentric | Prof. Dr. med. Martin T. R. Grapow | Herzchirurgie Klinikum 1 Universitätssptal Basel |
Herzchirurgie Klinikum 1 Universitätssptal Basel, Basel |
Ethikkommission Nordwest- und Zentralschweiz EKNZ | 16.04.2018 | |||||||
| 2018-00552 | Interactions between human innate immune cells and antibodies in health and disease | non clinical, involving persons | monocentric | A | Prof. Jörg D. Seebach | HUG-UniGE |
HUG-UniGE, Geneva |
Commission Cantonale d'éthique de la recherche Genève (CCER) | 11.07.2018 | ||||||
| 2018-00551 | Observance médicamenteuse et perception des effets indésirables du lithium sur la sexualité des personnes souffrant de trouble bipolaire | non clinical, involving persons | monocentric | A | Dr LUCAS Bénédicte | HUG |
HUG, Genève |
Commission Cantonale d'éthique de la recherche Genève (CCER) | 03.05.2018 | ||||||
| 2018-00550 | MULTIMODAL INVESTIGATION OF DISTINCT HYPNOTIC STATES | clinical trial | other clinical trials | monocentric | A | Dr. Mike Brügger | Zentrum für Zahnmedizin, Universität Zürich |
Center of Dental Medicine, University of Zurich, Zurich |
Kantonale Ethikkommission Zürich | 06.06.2018 | |||||
| 2018-00549 | Swiss study on longitudinal physical activity in youth- The-SOPHYA 2 study | non clinical, involving persons | monocentric | A | Prof. Dr. Nicole Porbst-Hensch | Swiss TPH |
Swiss TPH, Basel |
Ethikkommission Nordwest- und Zentralschweiz EKNZ | 07.05.2018 | yes | |||||
| 2018-00548 | Pulmonary vein isolation with versus without continued antiarrhythmic drug treatment in subjects with persistent atrial fibrillation: a prospective multi-centre randomized controlled clinical study | clinical trial | other clinical trials | monocentric | A | PD Dr. Richard Kobza | Department of Cardiology, AZ Sint-Jan AV |
Luzerner Kantonsspital, Luzern |
Ethikkommission Nordwest- und Zentralschweiz EKNZ | 25.06.2018 | |||||
| 2018-00547 | A Phase 3, Open-label Study Evaluating the Long-term Safety and Efficacy of VX-659 Combination Therapy in Subjects With Cystic Fibrosis Who Are Homozygous or Heterozygous for the F508del Mutation | clinical trial | drugs | phase 3 | multicentric | C | PD Dr. Alexander Möller | Vertex Pharmaceuticals |
Kinderspital Zürich, Zürich Lindenhofspital - Quartier Bleu, Bern |
Kantonale Ethikkommission Zürich | Kantonale Ethikkommission Bern | 11.12.2018 | yes | Study has ended | |
| 2018-00544 | Get Ready for Activity – Ambient Day Scheduling with Dementia | clinical trial | other clinical trials | monocentric | A | Prof. Dr. Edith Maier | FHS St.Gallen |
FHS St.Gallen, St.Gallen |
Ethikkommission Ostschweiz (EKOS) | 13.04.2018 | |||||
| 2018-00543 | „Prospective, randomized, controlled, parallel group study to compare a new needle navigation device for CT-guided interventions to the conventional free-hand method“ | clinical trial | medical devices | monocentric | A1 | Prof. Dr. med. Luca Remonda | Kantonsspital Aarau |
Kantonsspital Aarau, Aarau |
Ethikkommission Nordwest- und Zentralschweiz EKNZ | 22.05.2018 | Study has ended | ||||
| 2018-00542 | CQGE031C2202 - A multicenter, randomized, double-blind, placebo-controlled phase 2b dose-finding study to investigate the efficacy and safety of ligelizumab (QGE031) in adolescent patients | clinical trial | drugs | phase 2 | multicentric | C | PD Dr. Dr. Antonio Cozzio | Novartis Pharma Schweiz AG |
Kantonsspital, St. Gallen Kinderspital Zürich - Eleonorenstiftung, Zürich |
Ethikkommission Ostschweiz (EKOS) | Kantonale Ethikkommission Zürich | 31.07.2018 | yes | Study has ended | |
| 2018-00541 |
Tuned versus untuned ankle-foot orthoses in children and adolescents with cerebral palsy (Individualisierte Unterschenkelorthesen bei Kindern und Jugendlichen mit Zerebralparese) |
clinical trial | other clinical trials | monocentric | A | PD Dr. med. Erich Rutz | Universitäts-Kinderspital beider Basel (UKBB) |
UKBB, Basel |
Ethikkommission Nordwest- und Zentralschweiz EKNZ | 17.05.2018 | yes | Study has ended | |||
| 2018-00540 | Feasibility, validity and normative values of the computerized symbol digit modalities test (SDMT) in a Swiss pediatric cohort – a pilot study | non clinical, involving persons | monocentric | A | Dr. Karen Lidzba | Inselgruppe |
Inselgruppe, Kinderkliniken, Neuropädiatrie, Bern |
Kantonale Ethikkommission Bern | 06.06.2018 | yes | Study has ended | ||||
| 2018-00539 | Komplikationen und Outcome bei der Therapie der akuten myeloischen Leukämie (AML) | personal data/biological material | monocentric | Prof. Dr. med. Markus G. Manz | Division of Hematology |
University Hospital Zurich, Zurich |
Kantonale Ethikkommission Zürich | 08.05.2018 | |||||||
| 2018-00537 | Bazedoxifene as a possible strategy for treatment of pancreatic and gastric adenocarcinoma through the inhibition of IL6/GP130 signaling. | personal data/biological material | monocentric | Claudia Burkhardt | Hôpitaux Universitaires de Genève |
Hôpitaux Universitaires de Genève, Genève |
Commission Cantonale d'éthique de la recherche Genève (CCER) | 31.07.2018 | |||||||
| 2018-00536 | A phase III, multicenter, randomized, open-label study comparing Atezolizumab (Anti-PD-L1 antibody) in combination with adjuvant Anthracycline/Taxane-based chemotherapy versus chemotherapy alone in pa More ... | clinical trial | drugs | phase 3 | multicentric | C | Dr. Urs Breitenstein | F. Hoffmann-La Roche Ltd. |
Brust-Zentrum AG, Zürich Tumor Zentrum Aarau, Aarau Centre Hospitalier Universitaire Vaudois, Lausanne Brust-Zentrum AG, Zürich |
Kantonale Ethikkommission Bern | Ethikkommission Nordwest- und Zentralschweiz EKNZ, Kantonale Ethikkommission Zürich, Commission cantonale d'Éthique de la Recherche sur l'être humain Vaud (CER-VD) | 16.04.2019 | Study has ended | ||
| 2018-00535 | 3D planned reconstruction of severe ulna minus variance | non clinical, involving persons | monocentric | A | Prof. Andreas Schweizer | Universitätsklinik Balgrist |
Universitätsklinik Balgrist, Zürich |
Kantonale Ethikkommission Zürich | 27.04.2018 | Study has ended | |||||
| 2018-00534 | Modifizierter Agility Run Test: Psychometrische Eigenschaften in Kindern mit neurologischen Gangstörungen | clinical trial | other clinical trials | monocentric | A | Dr. Rob Labruyère | Rehabilitation Center for Children and Adolescents |
Rehabilitationszentrum für Kinder und Jugendliche, Affoltern am Albis |
Kantonale Ethikkommission Zürich | 25.05.2018 | yes | Study has ended | |||
| 2018-00533 | Effects of a time-delayed, pulsatile caffeine formula on sleep inertia, morning cognition, affect and subjective sleepiness in healthy volunteers | clinical trial | other clinical trials | monocentric | A | Prof. Dr. Hans-Peter Landolt | Universitiy of Zurich |
University of Zurich, Zurich |
Kantonale Ethikkommission Zürich | 22.05.2018 | Study has ended | ||||
| 2018-00531 | How emotion and stress and the mental modulation thereof affect memory in healthy subjects across development | non clinical, involving persons | monocentric | A | Prof. Patrik Vuilleumier | University of Geneva |
University of Geneva, Geneva |
Commission Cantonale d'éthique de la recherche Genève (CCER) | 24.10.2018 | yes | |||||
| 2018-00530 |
PIK3CA-related overgrowth spectrum (PROS) – Clinical characteristics, genetics, connective tissue abnormalities, and response to selective inhibitors |
non clinical, involving persons | monocentric | A | Dr. med. Martin Raphael Theiler Pang | University Children's Hospital Zurich |
University Children's Hospital, Zurich |
Kantonale Ethikkommission Zürich | 16.05.2018 | yes | |||||