BASEC ID Project title Type of project Type of clinical trial Study phase (clinical trials only) multi- / monocentric Category Principal investigator Sponsor Investigational sites Lead EC Local EC(s) Approval date Minors Study Ended
2016-01351 Brentuximab Vedotin and BeEAM high-dose chemotherapy (B-BeEAM) with autologous stem cell transplantation for CD30+ lymphomas, a phase I/II study (the BAL-trial). clinical trial drugs phase 2 monocentric B Prof. Thomas Pabst Inselspital, Universitätsklinik für Medizinische Onkologie Inselspital, Universitätsklinik für Medizinische Onkologie, Bern
Kantonale Ethikkommission Bern 14.08.2017
2016-01350 REPRISE EDGE: REpositionable Percutaneous Replacement of NatIve StEnotic Aortic Valve through Implantation of LOTUS EDGE Valve System – Evaluation of Performance and Safety clinical trial medical devices monocentric C Prof. Dr. Thomas Pilgrim Boston Scientific International S.A. Inselspital Bern, Bern
Kantonale Ethikkommission Bern 07.11.2016 Study has ended
2016-01349 Prognostic value of preoperative SPECT/CT in patients undergoing high tibial osteotomy due to medial compartment osteoarthritis: a retrospective study personal data/biological material monocentric PD Dr. med. Hirschmann Michael Kantonsspital Baselland, Department für Orthopädie und Traumatologie des Bewegungsapparates Kantonsspital Baselland, Klinik für Orthopädie und Traumatologie des Bewegungsapparates, Baselland
Ethikkommission Nordwest- und Zentralschweiz EKNZ 09.09.2016
2016-01348 Hip Arthroscopy versus Total Hip Arthroplasty in patients above 40 years of age personal data/biological material monocentric Prof. Claudio Dora Universtitätsklinik Balgrist Universtitätsklinik Balgrist, Zürich
Kantonale Ethikkommission Zürich 20.09.2016
2016-01347 Wirkung von körperlichen Interventionsformen auf körperliche Fitness, Befindlichkeit, kognitive Performanz, und Schlaf bei Patientinnen und Patienten mit diagnostizierter Multipler Sklerose (MS) clinical trial other clinical trials multicentric A PD Dr. Serge Brand Department of Sport, Exercise and Health, Basel
Klinik Valens, Valens
Ethikkommission Nordwest- und Zentralschweiz EKNZ Ethikkommission Ostschweiz (EKOS) 28.09.2016
2016-01346 Retrospective Evaluation of patients with esophageal food bolus impaction personal data/biological material monocentric PD Dr. med. Benjamin Misselwitz University Hospital, Division of Gastroenterology and Hepatology University Hospital Zurich, Zürich
Kantonale Ethikkommission Zürich 20.09.2016
2016-01345 Highly conformal hypofractionated radiotherapy (IGRT) in patients with biochemically relapsed oligometastatic adenocarcinoma of the prostate: a phase II prospective pilot study. clinical trial other clinical trials monocentric B Dr. med. Ngwa Che Azinwi IOSI IOSI, Bellinzona
Comitato etico cantonale Ticino 02.12.2016
2016-01344 Internet gaming disorder (IGD) in adolescents: a pilot study regarding the treatment potential of Multidimensional Family Therapy (MDFT) clinical trial other clinical trials monocentric A Mr./Philip/Nielsen Fondation Phénix Fondation Phénix, Geneva
Commission Cantonale d'éthique de la recherche Genève (CCER) 27.09.2016 yes
2016-01343 Assessment of the Hindfoot Using Three-Dimensional Computed Tomography Models personal data/biological material monocentric MD/Hintermann/Beat Kantonsspital Baselland Kantonsspital Baselland, Liestal
Ethikkommission Nordwest- und Zentralschweiz EKNZ 11.10.2016
2016-01342 Abbreviated breast MRI for cancer screening: are MIP projections of DCE sufficient for cancer detection? personal data/biological material monocentric Professor Jean-Yves Meuwly Centre Hospitalier universitaire vaudois (CHUV) CHUV, Lausanne
Commission cantonale d'Éthique de la Recherche sur l'être humain Vaud (CER-VD) 06.09.2016
2016-01341 Prévalence et facteurs de risque du sans-abrisme chez les usagers de drogues sous substitution: étude cas-témoins non clinical, involving persons monocentric A Ms Vanessa Vaucher HUG HUG, Genève
Commission Cantonale d'éthique de la recherche Genève (CCER) 20.12.2016
2016-01338 Etude des irradiations reçues par les patients lors des imageries peropératoires en radioscopie 2D, 3D et CT-scan en orthopédie pédiatrique d'urgence et programmée: étude exploratoire, comparative, mu More ... non clinical, involving persons multicentric A Prof. Dr. med. / Pierre / Lascombes Hôpitaux Universitaires de Genève Hôpitaux Universitaires de Genève, Genève
Centre Hospitalier Universitaire Vaudois, Lausanne
Commission Cantonale d'éthique de la recherche Genève (CCER) Commission cantonale d'Éthique de la Recherche sur l'être humain Vaud (CER-VD) 17.01.2017 yes
2016-01337 Early Identification of Patients needing immediate Palliative Care in the Emergency Department by a Novel Screening Tool - The first Swiss Emergency Department-based Palliative Care Program personal data/biological material monocentric Prof. Dr. med. D. Keller Lang Institut für Notfallmedizin des UniversitätsSpital Zürich Institut für Notfallmedizin des UniversitätsSpital Zürich, Zürich
Kantonale Ethikkommission Zürich 20.09.2016 Study has ended
2016-01336 Development and validation of a screener for clinical high risk states of psychosis in German speaking children, adolescents and young adults

[Entwicklung und Validierung eines Screening-Instrument More ...
non clinical, involving persons multicentric A Dr. phil. Chantal Michel Universitätsklinik für Kinder- und Jugendpsychiatrie und Psychotherapie Universitätsklinik für Kinder- und Jugendpsychiatrie und Psychotherapie, Bern
Department für Psychiatrie, Psychotherapie und Psychosomatik der Psychiatrischen Universitätsklinik Zürich, Zurich
Kantonale Ethikkommission Bern Kantonale Ethikkommission Zürich 01.12.2016 yes Study has ended
2016-01335 New ocular biomarkers for early detection of Alzheimer's disease non clinical, involving persons monocentric A Prof. Jean-François Démonet Centre Leenaards de la mémoire Centre Leenaards de la Mémoire (CLM), Lausanne
Commission cantonale d'Éthique de la Recherche sur l'être humain Vaud (CER-VD) 23.06.2017
2016-01334 CAIN457F3302- MAXIMISE (Managing AXIal Manifestations in Psoriatic Arthritis with SEcukinumab), a randomized, double-blind, double-dummy, placebo-controlled, multicenter, 52 week-study to assess the e More ... clinical trial drugs phase 3 multicentric B Prof. Dr. med. Andrea Rubbert-Roth Novartis Pharma Schweiz AG Kantonsspital St. Gallen, St. Gallen
Universitätsspital Basel, Basel
HFR Fribourg - Hôpital Cantonal, Fribourg
UniversitätsSpital Zürich, Zürich
Ethikkommission Ostschweiz (EKOS) Ethikkommission Nordwest- und Zentralschweiz EKNZ, Kantonale Ethikkommission Zürich, Commission cantonale d'Éthique de la Recherche sur l'être humain Vaud (CER-VD) 11.11.2016 Study has ended
2016-01333 Efficacy of Ondansetron in the treatment of low anterior resection syndrome (LARS): a multi-centre, randomized, double blind, placebo-controlled crossover study clinical trial drugs n/a multicentric B MD Dimitri Christoforidis Ospedale Regionale di Lugano, Civico e Italiano Ospedale Regionale di Lugano, Civico e Italiano, Lugano
CHUV, Lausanne
Comitato etico cantonale Ticino Commission cantonale d'Éthique de la Recherche sur l'être humain Vaud (CER-VD) 21.10.2016 Study has ended
2016-01332 Comparison of congenital and posttraumatic pathologies of the musculoskeletal system using 3D printed specimen and cross section image analysis personal data/biological material monocentric Prof. Dr. med. Christian Pfirrmann Universitätsklinik Balgrist Universitätsklinik Balgrist, Zürich
Kantonale Ethikkommission Zürich 23.11.2016
2016-01331 Pleural tap-guided antimicrobial treatment of pleuropneumonia in children personal data/biological material monocentric Prof. Dr. med. Christoph Berger Universitäts-Kinderspital Zürich Universitäts-Kinderspital Zürich, Zürich
Kantonale Ethikkommission Zürich 20.09.2016
2016-01330 Untersuchung des Effekts eines kognitiven Verfahrens auf die Angst vor Schlangen non clinical, involving persons monocentric A Prof. Dr. med. Dominique de Quervain Büro 305 Universität Basel, Basel
Ethikkommission Nordwest- und Zentralschweiz EKNZ 16.09.2016