| BASEC ID | Project title | Type of project | Type of clinical trial | Study phase (clinical trials only) | multi- / monocentric | Category | Principal investigator | Sponsor | Investigational sites | Lead EC | Local EC(s) | Approval date | Minors | Study Ended | |
|---|---|---|---|---|---|---|---|---|---|---|---|---|---|---|---|
| 2015-00049 |
"Cervical Range of Motion in Neck pain patients: A mixed methods study" (Beweglichkeit der Halswirbelsäule von Nackenschmerzpatienten) |
non clinical, involving persons | monocentric | A | Dr. Jaap Swaneburg | Balgrist University Clinic |
Balgrist University Clinic, Zurich |
Kantonale Ethikkommission Zürich | 18.01.2016 | Study has ended | |||||
| 2015-00044 | M13-549: A Phase III, Randomized, Double-Blind Study Comparing ABT-494 to Placebo in Subjects with Moderately to Severely Active Rheumatoid Arthritis Who Are on a Stable Dose of Conventional Synthetic More ... | clinical trial | drugs | phase 3 | multicentric | C | Prof. Dr. Jean Dudler | AbbVie AG |
HFR Kantonsspital Freiburg, Rheumatologie, 1708 Freiburg Kantonsspital Aarau, Abteilung Rheumatologie, Aarau |
Commission cantonale d'Éthique de la Recherche sur l'être humain Vaud (CER-VD) | Ethikkommission Nordwest- und Zentralschweiz EKNZ | 23.02.2016 | Study has ended | ||
| 2015-00043 | M13-545: A Phase 3, Randomized, Double-Blind Study Comparing ABT-494 Once Daily Monotherapy to Methotrexate (MTX) Monotherapy in MTX-Naïve Subjects with Moderately to Severely Active Rheumatoid Arthri More ... | clinical trial | drugs | phase 3 | monocentric | C | Prof. Dr. Jean Dudler | AbbVie AG |
Service de rhumatologie HFR Fribourg – Hôpital Cantonal, Fribourg |
Commission cantonale d'Éthique de la Recherche sur l'être humain Vaud (CER-VD) | 14.03.2016 | Study has ended | |||
| 2015-00042 |
SAKK 16/14 Anti-PD-L1 antibody MEDI4736 in addition to neoadjuvant chemotherapy in patients with stage IIIA(N2) non-small cell lung cancer (NSCLC). A multicenter single-arm phase II trial. |
clinical trial | drugs | phase 2 | multicentric | C | Dr. med. Sacha Rothschild | SAKK |
Universitätsspital Basel, Basel Inselspital Bern, Bern Spital STS AG Thun, Thun Kantonspital Aarau, Aarau Kantonsspital Baden, Baden Luzerner Kantonsspital, Luzern St. Claraspital, Basel Hôpitaux Univ More ... |
Ethikkommission Nordwest- und Zentralschweiz EKNZ | Ethikkommission Nordwest- und Zentralschweiz EKNZ, Ethikkommission Ostschweiz (EKOS), Kantonale Ethikkommission Bern, Kantonale Ethikkommission Zürich, Commission cantonale d'Éthique de la Recherche s More ... | 30.03.2016 | |||
| 2015-00041 | Factors predicting the forgotten joint score after total knee arthroplasty. | personal data/biological material | monocentric | MD Henrik Behrend | Dep of Orthopaedic Surgery, KSSG |
KSSG, St. Gallen |
Ethikkommission Ostschweiz (EKOS) | 07.12.2015 | |||||||
| 2015-00040 |
A Phase 3, Double-Blind, Randomized, Long-Term, Placebo-Controlled, Multicenter Study Evaluating the Safety and Efficacy of Obeticholic Acid in Subjects with Nonalcoholic Steatohepatitis |
clinical trial | drugs | phase 3 | multicentric | C | Prof. Dr. Annalisa Berzigotti | Intercept Pharma Switzerland GmbH |
University Clinic of Visceral Surgery and Medicine, Bern Kantonsspital St. Gallen, St. Gallen EPATOCENTRO TICINO, Lugano USZ, University of Zurich, Zürich |
Kantonale Ethikkommission Bern | Ethikkommission Ostschweiz (EKOS), Kantonale Ethikkommission Zürich, Comitato etico cantonale Ticino | 01.06.2016 | |||
| 2015-00039 | BIOTRONIK – Safety and clinical performance of the self-expanding transcatheter BIOVALVE prosthesis in subjects with severe symptomatic calcified aortic valve stenosis suitable for transfemoral transc More ... | clinical trial | medical devices | monocentric | C2 | Prof. Robert Bauernschmitt | BIOTRONIK AG - Clinical Affairs |
UniversitätsSpital Zürich - Klinik für Herz- und Gefässchirurgie, Zürich |
Kantonale Ethikkommission Zürich | 08.03.2016 | |||||
| 2015-00038 |
Auswirkungen der Implementierung eines Gerinnungsmanagement- Algorithmus bei herzchirurgischen Patienten – Eine Qualitätskontrolle Impact of a coagulation management algorithm in cardiac surgery - More ... |
personal data/biological material | monocentric | Prof. Dr. Christoph Hofer | Institut für Anästhesiologie und Intensivmedizin Stadtspital Triemli |
Institut für Anästhesiologie und Intensivmedizin Stadtspital Triemli, Zurich |
Kantonale Ethikkommission Zürich | 22.12.2015 | |||||||
| 2015-00037 | Predictive biomarkers of individual trajectories in elderly persons with subtle cognitive decline | non clinical, involving persons | monocentric | A | Professor Panteleimon Giannakopoulos | Hôpitaux Universitaires de Genève |
Hôpitaux Universitaires de Genève, Genève |
Commission Cantonale d'éthique de la recherche Genève (CCER) | 08.12.2016 | ||||||
| 2015-00035 | DEVELOPMENT OF A SYSTEM TO ASSESS LOCOMOTION OF FRAIL OLDER ADULTS IN TWO DIFFERENT ENVIRONMENTS | non clinical, involving persons | monocentric | A | Dr. Amandine Dubois | University of Fribourg |
University of Fribourg, Fribourg |
Commission cantonale d'Éthique de la Recherche sur l'être humain Vaud (CER-VD) | 02.02.2016 | Study has ended | |||||
| 2015-00034 | Prevalence of HPV infection using self-sampling screening and monitoring the Earlier Impact of HPV-Vaccination Program in Switzerland | clinical trial | medical devices | monocentric | A | Prof Patrick Petignat | Geneva university hospital |
Hopital universitaire de Geneve, geneva |
Commission Cantonale d'éthique de la recherche Genève (CCER) | 05.01.2016 | Study has ended | ||||
| 2015-00033 | A Phase I/II, multicenter, open-label, dose-escalation study of the safety and pharmacokinetics of cobimetinib in pediatric and young adult patients with previously treated solid tumors | clinical trial | drugs | phase 1 | monocentric | C | Dr. Nicolas Gerber | F. Hoffmann-La Roche Ltd. |
Universitäts-Kinderspital, Zürich |
Kantonale Ethikkommission Zürich | 15.07.2016 | yes | Study has ended | ||
| 2015-00032 |
The effect of biopolymer based lipid emulsions on GI function, GI peptide response and satiation in healthy volunteers; a randomized, double blind, unbalanced threeway crossover study. |
clinical trial | other clinical trials | monocentric | B | Dr. Andreas Setingoetter | University Hospital Zurich |
University Hospital Zurich, Zurich |
Kantonale Ethikkommission Zürich | 01.04.2016 | Study has ended | ||||
| 2015-00031 | Double-blind, randomized, placebo-controlled, phase III study on the efficacy and tolerability of a 48-week treatment with two different doses of budesonide effervescent tablets vs. placebo for mainte More ... | clinical trial | drugs | phase 3 | multicentric | C | Dr. med. Alain Schoepfer | Dr. Falk Pharma GmbH |
University Hospital Lausanne/CHUV Division of Gastroenterology and Hepatology, Lausanne Praxis für Gastroenterologie, Römerstraße 7, CH-4600 Olten Universitätsklinik Basel Abteilung für Gastroenterolo More ... |
Commission cantonale d'Éthique de la Recherche sur l'être humain Vaud (CER-VD) | Ethikkommission Nordwest- und Zentralschweiz EKNZ, Kantonale Ethikkommission Zürich | 25.05.2016 | Study has ended | ||
| 2015-00030 | Etude sur le vécu de l'instauration du mode d'alimentation du nouveau-né à la maternité chez les mères ayant accouché au CHUV en fonction de leurs critères de choix et de leurs connaissances prénatale More ... | non clinical, involving persons | monocentric | A | Ms Avignon Valérie | Centre hospitalier Universitaire Vaudois |
CHUV, Lausanne |
Commission cantonale d'Éthique de la Recherche sur l'être humain Vaud (CER-VD) | 06.01.2016 | ||||||
| 2015-00029 | Impact of 2014-2015 influenza season on the activity and workload of an emergency service | personal data/biological material | monocentric | Professeur Bertrand Yersin | Service des Urgences du CHUV |
CHUV, Lausanne |
Commission cantonale d'Éthique de la Recherche sur l'être humain Vaud (CER-VD) | 25.01.2016 | |||||||
| 2015-00027 | Myo-inositol and chiro-inositol quantification in plasma and urine : method development and potential interaction with pregnancy state | non clinical, involving persons | monocentric | A | Dr Maurice Beaumont | Nestlé Research Center |
Nestlé Research Center, Lausanne |
Commission cantonale d'Éthique de la Recherche sur l'être humain Vaud (CER-VD) | 18.11.2015 | Study has ended | |||||
| 2015-00026 | Implementation of the Flow Mediated Dilation Method at NRC/Metabolic Unit: training of operators on healthy volunteers | non clinical, involving persons | monocentric | A | Maurice Beaumont, MD, PhD | Nestlé Research Center |
Nestlé Research Center, Lausanne |
Commission cantonale d'Éthique de la Recherche sur l'être humain Vaud (CER-VD) | 06.01.2016 | Study has ended | |||||
| 2015-00024 | Effects of empagliflozin an SGLT2-inhibitor on healthy volunteers with induced hypotonic hyponatremia - the DIVE-study | clinical trial | drugs | n/a | monocentric | C | Prof / Mirjam / Christ | Endokrinologie, Universitätsspital Basel |
Endocrinology , Basel |
Ethikkommission Nordwest- und Zentralschweiz EKNZ | 08.01.2016 | Study has ended | |||
| 2015-00023 | GS-US-326-1100: A Combined Phase 2/3, Double-Blind, Randomized, Placebo-Controlled, Induction and Maintenance Study Evaluating the Safety and Efficacy of GS-5745 in Subjects with Moderately to Severel More ... | clinical trial | drugs | phase 2 | multicentric | C | Prof. Dr Gerhard Rogler | Gilead Sciences |
USZ, Zürich Gastroenterologische Praxis Balsiger, Seibold & Partner, Bern USB Gastroenterologie und Hepathologie , Basel |
Kantonale Ethikkommission Zürich | Ethikkommission Nordwest- und Zentralschweiz EKNZ, Kantonale Ethikkommission Bern | 18.03.2016 | Study has ended | ||