| BASEC ID | Project title | Type of project | Type of clinical trial | Study phase (clinical trials only) | multi- / monocentric | Category | Principal investigator | Sponsor | Investigational sites | Lead EC | Local EC(s) | Approval date | Minors | Study Ended | |
|---|---|---|---|---|---|---|---|---|---|---|---|---|---|---|---|
| 2025-D0013 | Robotic-assisted bronchoscopy under moderate sedation with propofol: A single-center pilot study. | clinical trial | medical devices | monocentric | C1 | Dr. med. Carolin Steinack | Universitätsspital Zürich |
Universitätsspital Zürich, Zürich |
Kantonale Ethikkommission Zürich | 05.08.2025 | |||||
| 2025-D0012 |
A mobile application as supportive treatment of menstrual cycle irregularities. A randomized controlled trial. Supporting your natural cycle. |
clinical trial | medical devices | monocentric | A1 | Dr. med. Marietta Gulz | University Hospital Bern |
Frauenklinik Inselpspital Bern, Bern |
Kantonale Ethikkommission Bern | 30.07.2025 | |||||
| 2025-D0011 | Pelvic Functional magnetic stimulation on pain in endometriosis patients – a prospective non randomised, non blinded single centre observational trial | clinical trial | medical devices | monocentric | A1 | Dr. med. Daniela Hagen | Kantonsspital Winterthur |
Kantonsspital Winterthur, Winterthur |
Kantonale Ethikkommission Zürich | 05.09.2025 | |||||
| 2025-D0010 | A post-market, interventional, confirmative clinical investigation to evaluate the performance and the safety of “LMW - CL - HA – FACE/BODY” used as intended for the restoration of the physiological v More ... | clinical trial | medical devices | monocentric | A2 | Dr. med. Corrado Parodi | Rose Pharma SA |
Ospedale Regionale di Lugano, Viganello |
Comitato etico cantonale Ticino | 25.03.2025 | |||||
| 2025-D0009 | Global pilot study of rEnal and hepatic coMbINed denervatIon in subjects with Uncontrolled Hypertension with and without High Cardiovascular Risk (SPYRAL GEMINI Pilot Study) | clinical trial | medical devices | monocentric | C2 | Dr. Lucas Lauder | Medtronic Vascular, Inc. |
Universitätsspital Basel, Basel |
Ethikkommission Nordwest- und Zentralschweiz EKNZ | 11.08.2025 | |||||
| 2025-D0008 |
BIOTRONIK – A Prospective Multicenter Single-Arm Study to Assess the Safety and Effectiveness of the Orsiro Mission 48- mm Sirolimus-Eluting Coronary Stent System for the Treatment of Subjects with A More ... |
clinical trial | medical devices | multicentric | C2 | Prof. Dr. med.. Gregor Leibundgut | BIOTRONIK AG |
University Hospital Basel, Basel Istituto Cardiocentro Ticino, Via Tesserete 48 |
Ethikkommission Nordwest- und Zentralschweiz EKNZ | Comitato etico cantonale Ticino | 17.03.2025 | ||||
| 2025-D0007 | Randomized controlled trial comparing closed face masks vs surface guided radiation therapy for head and neck radiotherapy (NoMask Study) | clinical trial | medical devices | monocentric | A1 | Prof. Dr. med. Panagiotis Balermpas | Universitätsspital Zürich |
Universitätsspital Zürich, Zürich |
Kantonale Ethikkommission Zürich | 15.04.2025 | |||||
| 2025-D0005 | Intra-individual comparison of PET scans of the Biograph Vision 600 with the new Biograph Vision.X PET/CT | clinical trial | medical devices | monocentric | A1 | Pr Valentina Garibotto | HUG |
HUG, Geneva |
Commission Cantonale d'éthique de la recherche Genève (CCER) | 08.04.2025 | |||||
| 2025-D0004 | Safety and feasibility of ultrasound-assisted non-invasive measurement of compressibility of the thyroid gland in patients scheduled for surgical removal | clinical trial | medical devices | monocentric | C2 | PD Dr. med. Urs Borner | Insel Gruppe |
Insel Gruppe, Bern |
Kantonale Ethikkommission Bern | 28.05.2025 | |||||
| 2025-D0003 | Development of Artificial Intelligence algorithms from respiratory sounds recorded with the Pneumoscope in children and adolescents with wheezing disorders. | clinical trial | medical devices | monocentric | C2 | Isabelle Ruchonnet-Métrailler | Geneva University Hospitals |
HUG, Genève |
Commission Cantonale d'éthique de la recherche Genève (CCER) | 05.06.2025 | yes | ||||
| 2025-D0001 | Immediate loading of immediate single implants with a definitive crown in premolar regions: A prospective single-arm clinical trial | clinical trial | medical devices | monocentric | A1 | Dr. Med. Dent. Duygu Karasan | University of Geneva |
University of Geneva, Geneva |
Commission Cantonale d'éthique de la recherche Genève (CCER) | 07.05.2025 | |||||
| 2025-02655 | Accuracy of Maxillary Positioning in Semi-Guided vs. Splint-Based Orthognathic Surgery | personal data/biological material | monocentric | Prof. Dr. mult. Florian M. Thieringer | Universitätsspital Basel |
Universitätsspital Basel, Basel |
Ethikkommission Nordwest- und Zentralschweiz EKNZ | 16.02.2026 | |||||||
| 2025-02654 | Impact of clinical context information on the diagnostic accuracy of Large Language Models (LLMs) in radiologic image interpretation: a comparative evaluation of proprietary an open multimodal models | personal data/biological material | monocentric | Prof. Dr. med. T. Niemann, LA Kardiovaskuläre & Thorakale Radiologie |
Radiologie Kantonsspital Baden, 5404 Baden |
Ethikkommission Nordwest- und Zentralschweiz EKNZ | 16.01.2026 | ||||||||
| 2025-02653 |
Extended interval dosing treatment with Anti-CGRP(R) Monoclonal Antibodies in Migraine Prophylaxis (EXTRA-M Study) |
non clinical, involving persons | monocentric | A | Prof. dr.ssa med. Chiara Zecca | Ente Ospedaliero Cantonale, Ospedale Regionale di Lugano |
Ente Ospedaliero Cantonale, Ospedale Regionale di Lugano, Lugano |
Comitato etico cantonale Ticino | 17.02.2026 | ||||||
| 2025-02650 | Tumor microenvironment transcriptomic profiling of non-melanoma skin cancer in solid organ transplant recipients versus non-transplant patients: a single-centre prospective observational cohort study | non clinical, involving persons | monocentric | A | Dr.med. Alexandra Junge |
Universitätsklinik für Dermatologie, Bern |
Kantonale Ethikkommission Bern | 09.02.2026 | |||||||
| 2025-02645 | Textbook outcome on recovery after colorectal surgery within an ERAS program, a retrospective study | personal data/biological material | monocentric | Prof. Dr.med Dimitri Christoforidis | EOC |
EOC, Lugano |
Comitato etico cantonale Ticino | 21.01.2026 | |||||||
| 2025-02644 | Histological Mapping of the Extensor Hood Central Slip in Zone 3 and 4 | deceased persons | monocentric | Herr PD Dr. med. Thomas Giesen | Luzerner Kantonsspital |
Kantonsspital Luzern, Klinik für Hand- und plastische Chirurgie, Luzern |
Ethikkommission Nordwest- und Zentralschweiz EKNZ | 04.03.2026 | |||||||
| 2025-02640 | Ventilatory efficiency during exercise in chronic thromboembolic pulmonary hypertension (CTEPH) and pulmonary arterial hypertension (PAH) pre- and post-treatment. | personal data/biological material | monocentric | Prof Dr med Esther Irene Schwarz | University Hospital Zurich |
University Hospital Zurich, Zurich |
Kantonale Ethikkommission Zürich | 06.03.2026 | |||||||
| 2025-02638 | Switching to the biosimilar ranibizumab-nuna for the intravitreal treatment of retinal diseases – a real-world study | personal data/biological material | monocentric | PD Dr. med. Pascal Knecht-Bösch | Augenklinik Wettingen |
Augenklinik Wettingen, Wettingen |
Ethikkommission Nordwest- und Zentralschweiz EKNZ | 27.01.2026 | |||||||
| 2025-02637 | Cardiac Safety of anti-HER2 treatment in HER2-Positive and HER2-low Breast Cancer patients: Identifying Low- and High-Risk Patients for Echocardiographic Follow-up Simplification. | personal data/biological material | monocentric | Dre Sarah Hugelshofer | CHUV |
CHUV, Lausanne |
Commission cantonale d'Éthique de la Recherche sur l'être humain Vaud (CER-VD) | 26.02.2026 | |||||||