| BASEC ID | Project title | Type of project | Type of clinical trial | Study phase (clinical trials only) | multi- / monocentric | Category | Principal investigator | Sponsor | Investigational sites | Lead EC | Local EC(s) | Approval date | Minors | Study Ended | |
|---|---|---|---|---|---|---|---|---|---|---|---|---|---|---|---|
| 2025-01991 | Lipidomics profile changes with Levothyroxine treatment vs. placebo to explore potential mechanisms for reducing cardiovascular disease risk among adults with subclinical hypothyroidism | personal data/biological material | monocentric | Prof. Nicolas Rodondi | BIHAM, University of Berne |
BIHAM, University of Bern, Bern |
Kantonale Ethikkommission Bern | 04.12.2025 | |||||||
| 2025-01990 | The role of preoperative MRI in patients with resectable and borderline-resectable pancreatic cancer: a Swiss single-center retrospective analysis | personal data/biological material | monocentric | Prof. Dr. med. Martin Bolli | Luzerner Kantonspital |
Luzerner Kantonspital, Lucerne |
Ethikkommission Nordwest- und Zentralschweiz EKNZ | 29.10.2025 | |||||||
| 2025-01986 | PSYchological factors influencing treatment Decision-Making in Prostate adenoCarcinoma: a retrospective and prospective interdisciplinary study – PSY D-M PCa | non clinical, involving persons | monocentric | A | Dr. med. Davide Bosetti | Centro Prostata della Svizzera Italiana EOC (CPSI) |
Centro Prostata della Svizzera Italiana EOC (CPSI), Bellinzona |
Comitato etico cantonale Ticino | 27.11.2025 | ||||||
| 2025-01983 | SoLeMet - Establishment and validation of a bioanalytical method to measure levels of biomarkers of CYP2D6 metabolic activity in healthy volunteers – a prospective observational study | non clinical, involving persons | monocentric | A | Prof. Dr. med. Henriette Meyer zu Schwabedissen / Prof. Dr. Samuel Allemann | Universität Basel |
University of Basel | Department Pharmaceutical Sciences | Biopharmacy Pharmaceutical Care, Basel |
Ethikkommission Nordwest- und Zentralschweiz EKNZ | 04.11.2025 | ||||||
| 2025-01978 | Surgical Treatment of Malignant Mitral Valve Prolapse: Literature Review and Single-Centre Case Series | personal data/biological material | monocentric | Prof. Matthias Kirsch | CHUV - Chirurgie cardiaque |
CHUV, Lausanne |
Commission cantonale d'Éthique de la Recherche sur l'être humain Vaud (CER-VD) | 06.10.2025 | |||||||
| 2025-01976 | Traumatherapie: Veränderungen der Symptomschwere | personal data/biological material | monocentric | Dr. phil. Louisa Lorenz | Klinik im Hasel AG |
Klinik im Hasel AG, Baden |
Ethikkommission Nordwest- und Zentralschweiz EKNZ | 15.10.2025 | |||||||
| 2025-01975 | Machine Learning for Predicting Chemotherapy-Induced Adverse Drug Reactions and Chemotoxicity in Patients with Solid Malignomas: A retrospective cohort study | personal data/biological material | monocentric | PD Dr. med. Marcus Vetter | Canton Hospital Baselland |
Zentrum Onkologie & Hämatologie, Kantonsspital Baselland, Liestal |
Ethikkommission Nordwest- und Zentralschweiz EKNZ | 18.11.2025 | |||||||
| 2025-01971 | A2NOF: A Cemented Short Stem for Femoral Neck Fractures: A Non-Interventional Observational Report | personal data/biological material | monocentric | Prof. Dr. med. Dr. Karl Stoffel | Orthopädie und Traumatologie |
Orthopädie und Traumatologie, Universitätsspital Basel, Basel |
Ethikkommission Nordwest- und Zentralschweiz EKNZ | 20.10.2025 | |||||||
| 2025-01968 | Auswirkung eines Multiagentensystems zur Detektion von Medikationsfehler auf die Prävalenz von durch Antikoagulantien verursachte Blutungen und Kosten-Nutzen-Analyse des Multiagentensystems | personal data/biological material | monocentric | Seraina Herzig | Kantonsspital Aarau AG |
Kantonsspital Aarau, Aarau |
Ethikkommission Nordwest- und Zentralschweiz EKNZ | 26.11.2025 | |||||||
| 2025-01967 | CKJX839A12309 - A randomized, double-blind, placebo-controlled study to evaluate efficacy and safety of early in hospital initiation of inclisiran treatment in patients with acute coronary syndromes: More ... | clinical trial | drugs | phase 3 | multicentric | C | Dr. med. Matthias Bossard | Novartis Pharma Schweiz AG |
Luzerner Kantonsspital, Luzern Inselspital, Universitätsspital Bern 41 Universitätsklinik für Kardiologie, Herz Gefäss Zentrum, Bern Département de cardiologie, Hôpitaux Universitaires de Genève, Gene More ... |
Ethikkommission Nordwest- und Zentralschweiz EKNZ | Kantonale Ethikkommission Bern, Commission Cantonale d'éthique de la recherche Genève (CCER) | 28.11.2025 | |||
| 2025-01961 | Evaluation of an advanced practice nurse supported care model in delirium management in a hospital: a multi method study | personal data/biological material | monocentric | Michael Simon | University of Basel, Institute of Nursing Science |
Universität Basel, Institut für Pflegewissenschaft, Basel |
Ethikkommission Nordwest- und Zentralschweiz EKNZ | 14.11.2025 | |||||||
| 2025-01960 | Fetal Tissue Engineering | personal data/biological material | multicentric | Prof. Dr. med. Ueli Möhrlen | Universitäts-Kinderspital Zürich |
Universitäts-Kinderspital, Zürich Universitätsspital, Zürich |
Kantonale Ethikkommission Zürich | Kantonale Ethikkommission Zürich | 02.12.2025 | ||||||
| 2025-01953 | Exploring the Relationship Between Blood Glucose Levels and Age | personal data/biological material | monocentric | Quinten Johnson | ETH Zürich |
ETH Zürich, Zürich |
Kantonale Ethikkommission Zürich | 14.10.2025 | |||||||
| 2025-01946 | Evaluation of an APN-led Transitional Pain Service to Prevent Chronic Postsurgical Pain after Spinal Surgery: A Pilot Study at University Hospital Basel | clinical trial | other clinical trials | monocentric | A | Dr. Sabine Valenta | Institut für Pflegewissenschaft, Universität Basel |
Universität Basel, Institut für Pflegewissenschaft (INS), Basel |
Ethikkommission Nordwest- und Zentralschweiz EKNZ | 30.10.2025 | |||||
| 2025-01940 | DO-HEALTH BioAge III Organ aging clock | personal data/biological material | monocentric | Prof. Dr. med., DrPH Heike A. Bischoff-Ferrari | Universitäre Altersmedizin FELIX PLATTER |
Universitäre Altersmedizin FELIX PLATTER, Basel |
Ethikkommission Nordwest- und Zentralschweiz EKNZ | 08.10.2025 | |||||||
| 2025-01935 | Readmission to psychiatric inpatient care: temporal trends and contributing factors - An explorative single-center study using routinely collected data | personal data/biological material | monocentric | Beatrice Gehri | Institute of Nursing Science |
Institute of Nursing Science, University Basel, Basel |
Ethikkommission Nordwest- und Zentralschweiz EKNZ | 27.10.2025 | |||||||
| 2025-01932 |
Retrospective analysis of clinical and morphology characteristics and outcomes of infantile hemangiomas (IH) in preterm vs. term infants |
personal data/biological material | monocentric | PD Dr. med. Martin Theiler Pang | University Children's Hospital Zurich |
University Children's Hospital Zurich, Pediatric Skin Center, Dermatology Department, Zurich |
Kantonale Ethikkommission Zürich | 28.11.2025 | |||||||
| 2025-01929 | Network Biomarkers for Gait in Parkinson’s Disease: Integrating Kinematics and Brain Fibers | personal data/biological material | monocentric | Prof. Dr. William R. Taylor | Department of Health Sciences and Technology, ETH Zürich |
Department of Health Sciences and Technology, ETH Zürich, Zürich |
Kantonale Ethikkommission Zürich | 24.10.2025 | |||||||
| 2025-01928 | Fluorescence visualization and Image Quality Evaluation of Digital visualization during standard of care procedure in the cerebral vascular area as well as blood flow during plastic and reconstructive More ... | non clinical, involving persons | monocentric | A | Prof. Dr. med. Raphael Guzman | Leica Microsystems (Schweiz) AG |
University Hospital Basel, Department of Neurosurgery, Basel |
Ethikkommission Nordwest- und Zentralschweiz EKNZ | 26.11.2025 | ||||||
| 2025-01926 | Fistula Immuno-Biological Evaluation of Recurrence (FIBER) | personal data/biological material | monocentric | Dr. med. Michael Huguenin-Dezot | Universitätsklinik für Viszerale Chirurgie und Medizin Bauchzentrum Bern, Inselspital |
Universitätsklinik für Viszerale Chirurgie und Medizin Bauchzentrum Bern, Inselspital, Bern |
Kantonale Ethikkommission Bern | 19.11.2025 | |||||||