| BASEC ID | Project title | Type of project | Type of clinical trial | Study phase (clinical trials only) | multi- / monocentric | Category | Principal investigator | Sponsor | Investigational sites | Lead EC | Local EC(s) | Approval date | Minors | Study Ended | |
|---|---|---|---|---|---|---|---|---|---|---|---|---|---|---|---|
| 2018-02176 | A prospective, open label, single arm, clinical study to evaluate the effect of Safinamide on sleep quality and polysomnographic parameters in patients with Parkinson’s Disease: the Safe Sleep study | clinical trial | drugs | n/a | monocentric | A | Prof. Dr. med. Dr. phil. med. Alain Kaelin | Neurocenter of Southern Switzerland – Ente Ospedaliero Cantonale |
Neurocenter of Southern Switzerland – Ente Ospedaliero Cantonale, Lugano |
Comitato etico cantonale Ticino | 15.02.2019 | ||||
| 2018-02175 | Validation of a German version of the questionnaire ‘Needs Assessment Tool: Progressive Disease – Heart Failure (NAT: PD-HF) | non clinical, involving persons | monocentric | A | Prof. Dr. med. Steffen Eychmüller | University Centre for Palliative Care, Inselspital |
Inselspital, Bern |
Kantonale Ethikkommission Bern | 05.02.2019 | ||||||
| 2018-02174 | Lung clearance index for the early detection and monitoring of lung allograft dysfunction after adult lung transplantation | non clinical, involving persons | monocentric | A | Christian Benden | University of Zurich |
University Hospital Zurich, Zurich |
Kantonale Ethikkommission Zürich | 23.01.2019 | Study has ended | |||||
| 2018-02173 | Transanal Total Mesorectal Excision (TaTME) versus conventional TME (cTME) for MRI-defined low rectal cancer: A multi-center propensity score-matched analysis of oncological outcomes | personal data/biological material | monocentric | Dr. Jeremy Meyer | AMSTERDAM UMC |
Hôpitaux Universitaires de Genève, Genève |
Commission Cantonale d'éthique de la recherche Genève (CCER) | 14.05.2019 | |||||||
| 2018-02172 | Histopathologic and moleculargenetic analysis of factors in endosalpingiosis compared to ovarian cancer, tubal tissue, endometriosis as well as eutopic endometrial tissue | personal data/biological material | monocentric | Dr Eleftherios Pierre Samartzis | University Hospital Zurich, Dept. of Gynecology |
Dept. of Gynecology, University Hospital Zurich, Zurich |
Kantonale Ethikkommission Zürich | 19.12.2018 | |||||||
| 2018-02171 |
Wise Cortical Strip for Intraoperative Neurophysiological Monitoring - A prospective, interventional, multi-center, open-label, premarket study to evaluate safety, performance and usability of the W More ... |
clinical trial | medical devices | multicentric | C | Dr. med. Marian Neidert | Wise S.r.l. |
UniversitätsSpital, Zürich Insepspital Bern University Hospital, Bern Luzerner Kantonsspital, Luzern |
Kantonale Ethikkommission Zürich | Ethikkommission Nordwest- und Zentralschweiz EKNZ, Kantonale Ethikkommission Bern | 21.03.2019 | Study has ended | |||
| 2018-02170 | Entwicklung einer diagnostischen Probabilitätsfunktion (DPF) bei Patienten mit rezidivierenden Thoraxschmerzen zur Schätzung der Wahrscheinlichkeit einer relevanten koronaren Herzkrankheit | personal data/biological material | monocentric | PD. Dr. med. Christian Schmied | University Zurich |
Clinic for Cardiology, University Hospital, Zuerich |
Kantonale Ethikkommission Zürich | 17.12.2018 | Study has ended | ||||||
| 2018-02169 |
The effect of prebiotics on iron absorption in women with low iron stores: Determination of a dose-dependent effect of galacto-oligosaccharides on iron absorption, with and without addition of asc More ... |
clinical trial | other clinical trials | monocentric | A | Dr. Isabelle Herter-Aeberli | Laboratory of Human Nutrition, ETH Zurich |
Laboratory of human nutrition, ETH Zurich, Zürich |
Kantonale Ethikkommission Zürich | 08.03.2019 | Study has ended | ||||
| 2018-02168 | Early targeted biofilm-active antibiotic therapy in a 2-stage-exchange method for prosthetic hip-infection is associated with excellent infectiological and functional outcome | personal data/biological material | monocentric | Prof. Dr. med. Hubert Nötzli | Orthopädie Sonnenhof |
Orthopädie Sonnenhof, Bern |
Kantonale Ethikkommission Bern | 14.05.2019 | |||||||
| 2018-02167 | Proton Therapy of Neuroblastoma in the Paediatric Population at PSI: Experience and Outcome | personal data/biological material | monocentric | Prof.Dr.med. Damien C. Weber | Center for Proton Therapy at Paul Scherrer Institute |
Center for Proton Therapy at Paul Scherrer Institut, Villigen |
Ethikkommission Nordwest- und Zentralschweiz EKNZ | 10.12.2018 | Study has ended | ||||||
| 2018-02166 | Analysis of the Activity of the Human Immune System | non clinical, involving persons | monocentric | A | Dr. Mariagrazia Uguccioni | Institute for Research in Biomedicine |
Institute for Research in Biomedicine, Bellinzona |
Comitato etico cantonale Ticino | 12.12.2018 | ||||||
| 2018-02165 | Neue Prädiktoren zur klinischen Prognose durch die Analyse von Krankheitsverläufen der systemischen Sklerose | personal data/biological material | monocentric | Prof.Dr.med. Oliver Distler | Klinik für Rheumatologie |
Klinik für Rheumatologie, Zürich |
Kantonale Ethikkommission Zürich | 18.12.2018 | |||||||
| 2018-02164 | Overcoming psychomotor slowing in psychosis (OCoPS-P) – A 3-week, randomized, double-blind, placebo-controlled trial of add-on repetitive transcranial magnetic stimulation for psychomotor slowing in p More ... | clinical trial | medical devices | monocentric | A1 | Prof. Sebastian Walther | University Hospital of Psychiatry |
University of Bern, University Hospital of Psychiatry, Bern |
Kantonale Ethikkommission Bern | 12.03.2019 | Study has ended | ||||
| 2018-02163 | CAIN457M2301 - A randomized, double-blind, multicenter study assessing short (16 weeks) and long-term efficacy (up to 1 year), safety, and tolerability of 2 subcutaneous secukinumab dose regimens in a More ... | clinical trial | drugs | phase 3 | multicentric | B | PD Dr med Emmanuel Laffitte | Novartis Pharma Schweiz AG |
HUG, Geneve Inselspital Bern, Bern |
Commission Cantonale d'éthique de la recherche Genève (CCER) | Kantonale Ethikkommission Bern | 13.05.2019 | Study has ended | ||
| 2018-02162 |
CAIN457M2302 - A randomized, double-blind, multicenter study assessing short (16 weeks) and long-term efficacy (up to 1 year), safety, and tolerability of 2 subcutaneous secukinumab dose regimens in More ... |
clinical trial | drugs | phase 3 | multicentric | C | Dr med Christa-Maria Maniu | Novartis Pharma Schweiz AG |
CHUV, Lausanne UniversitätSpital Zürich, Zurich |
Commission cantonale d'Éthique de la Recherche sur l'être humain Vaud (CER-VD) | Kantonale Ethikkommission Zürich | 23.07.2019 | Study has ended | ||
| 2018-02160 | Visual migraine aura iconography | non clinical, involving persons | monocentric | A | PD Dr. med. Chiara Zecca | Ospedale Regionale di Lugano |
Ospedale Regionale di Lugano, Lugano |
Comitato etico cantonale Ticino | 06.05.2019 | Study has ended | |||||
| 2018-02159 | TEPStabil - Muscle function and dynamic and postural stability in patients receiving hip or knee arthroplasty | non clinical, involving persons | monocentric | A | Prof. Dr. Annegret Mündermann | University Hospital Basel |
University Hospital Basel, Basel |
Ethikkommission Nordwest- und Zentralschweiz EKNZ | 02.01.2019 | Study has ended | |||||
| 2018-02158 | Arrhythmias and Thromboembolism in Adult Patients with Transposition of the Great Arteries | personal data/biological material | monocentric | PD Dr. med. Thomas Wolber |
Universitäres Herzzentrum Zürich, Zürich |
Kantonale Ethikkommission Zürich | 08.01.2019 | ||||||||
| 2018-02157 | Prediction and prevention of thrombo-hemorragic complications in patients with liver cirrhosis: the role of thrombin generation assays and anticoagulant drugs | non clinical, involving persons | monocentric | A | Prof. Lorenzo Alberio | CHUV |
CHUV, Lausanne |
Commission cantonale d'Éthique de la Recherche sur l'être humain Vaud (CER-VD) | 10.01.2019 | Study has ended | |||||
| 2018-02156 | Nurse-facilitated multidisciplinary follow-up care in Heart Failure (UTILE): a pilot randomized controlled trial | clinical trial | other clinical trials | monocentric | A | PhD Petra Schäfer | Haute école de santé Fribourg / Hochschule für Gesundheit Freiburg |
Haute école de santé Fribourg / Hochschule für Gesundheitheit Freiburg (HEdS-FR, HES-SO), Fribourg/Freiburg |
Commission cantonale d'Éthique de la Recherche sur l'être humain Vaud (CER-VD) | 22.01.2019 | Study has ended | ||||